截至2020年9月,關國良發表SCI論文220餘篇,以第一或通訊作者在New England Journal of Medicine、The Lancet Neurology、Nature Genetics、Brain、JAMA Neurology、Neurology等醫學期刊發表多篇論文,谷歌學術引用超過19600次。以第一作者在New England Journal of Medicine雜誌上發表關於癲癇預後的文章,是有記錄以來癲癇研究中被引用最多的原創臨床研究文章(引用超過4300次)。
代表性論文
Naganur VD, Kusmakar S, Chen Z, Palaniswami MS, Kwan P, O'Brien TJ. The utility of an automated and ambulatory device for detecting and differentiating epileptic and psychogenic non-epileptic seizures. Epilepsia Open. 2019 May 13;4(2):309-317. doi: 10.1002/epi4.12327.
Alsfouk BA, Alsfouk AA, Chen Z, Kwan P, Brodie MJ. Pharmacological outcomes in teenagers with newly diagnosed epilepsy: A 30-year cohort study. Epilepsia. 2019 Jun;60(6):1083-1090. doi: 10.1111/epi.15664.
Foster E, Holper S, Chen Z, Kwan P. Presentation and management of community-onset vs hospital-onset first seizures. Neurol Clin Pract. 2018 Oct;8(5):421-428. doi: 10.1212/CPJ.0000000000000524.
Wong JKL, Gui H, Kwok M, Ng PW, Lui CHT, Baum L, Sham PC, Kwan P, Cherny SS. Rare variants and de novo variants in mesial temporal lobe epilepsy with hippocampal sclerosis. Neurol Genet. 2018 Jun 11;4(3):e245. doi: 10.1212/NXG.0000000000000245.
Krauss GL, Perucca E, Kwan P, Ben-Menachem E, Wang X-F, Shih JJ, Patten A, Yang H, Williams B, Laurenza A. Final safety, tolerability, and seizure outcomes in patients with focal epilepsy treated with adjunctive perampanel for up to 4 years in an open-label extension of phase III randomized trials: Study 307. Epilepsia. 2018; 59 (4): 866 – 876.
Sivathamboo S, Perucca P, Velakoulis D, Jones NC, Goldin J, Kwan P, O’Brien TJ. Sleep disordered breathing in epilepsy: Epidemiology, mechanisms and treatment. Sleep. 2018; doi: 10.1093/sleep/zsy015. [Epub ahead of print].
Thevathasan A, Naylor J, Churilov L, Mitchell PJ, Dowling RJ, Yan B, Kwan P. Association between hemorrhagic transformation after endovascular therapy and poststroke seizures. Epilepsia. 2018; 59 (2): 403-409.
Chen Z, Churilov L, Chen Z, Naylor J, Koome M, Yan B, Kwan P. Association between implementation of a code stroke system and poststroke epilepsy. Neurology. 2018; 90(13): e1126-e1133. doi: 10.1212/WNL.0000000000005212.
McCormack M…..EPIGEN Consortium;, Pirmohamed M, Carleton BC; Canadian Pharmacogenomics Network for Drug Safety;, Cendes F, Lopes-Cendes I, Liao WP, O'Brien TJ, Sisodiya SM; EpiPGX Consortium;, Cherny S, Kwan P, Baum L; International League Against Epilepsy Consortium on Complex Epilepsies;, Cavalleri GL. Genetic variation in CFH predicts phenytoin-induced maculopapular exanthema in European-descent patients. Neurology. 2018; 90(4):e332-e341. doi: 10.1212/WNL.0000000000004853.
Soraya GV, Chan J, Nguyen TC, Hyunh DC, Abeyrathne CD, Chana G, Todaro M, Skafidas E, Kwan P. An Interdigitated Electrode Biosensor Platform for Rapid HLA-B*15:02 Genotyping for Prevention of Drug Hypersensitivity. Biosensors Bioelectronics. 2018; 111:174-183. doi: 10.1016/j.bios.2018.01.063.
Chen, Z., Brodie, M.J., Liew, D., Kwan, P. Treatment outcomes in patients with newly diagnosed epilepsy treated with established and new antiepileptic drugs a 30-year longitudinal cohort study. JAMA Neurology. 2018; 75(3):279-286. doi: 10.1001/jamaneurol.2017.3949.
Liu S, Shen Y, Shultz SR, Nguyen A, Hovens C, Adlard PA, Bush AI, Chan J, Kwan P, O’Brien TJ, Jones NC. Accelerated kindling epileptogenesis in Tg4510 tau transgenic mice, but not in tau knockout mice. Epilepsia. Accepted 20 June 2017.
Shi YW, Min FL, Zhou D, Qin B, Wang J, Hu FY, Cheung YK, Zhou JH, Hu XS, Zhou JQ, Zhou LM, Zheng ZZ, Pan J, He N, Liu ZS, Hou YQ, Lim KS, Ou YM, Hui-Ping Khor A, Ng CC, Mao BJ, Liu XR, Li BM, Kuan YY, Yi YH, He XL, Deng XY, Su T, Kwan P, Liao WP. HLA-A*24:02 as a common risk factor for antiepileptic drug-induced cutaneous adverse reactions. Neurology. 2017; 88(23):2183-2191. doi: 10.1212/WNL.0000000000004008.
Perucca P, Scheffer IE, Harvey AS, James PA, Lunke S, Thorne N, Gaff C, Regan BM, Damiano JA, Hildebrand MS, Berkovic SF, O'Brien TJ, Kwan P. Real-world utility of whole exome sequencing with targeted gene analysis for focal epilepsy. Epilepsy Res. 2017; 131:1-8. doi: 10.1016/j.eplepsyres.2017.02.001.
Chen Z, Liew D, Kwan P. Real-world cost-effectiveness of pharmacogenetic screening for epilepsy treatment. Neurology 2016; 86(12), 1086-94.
Chan J, Jones NC, Bush AI, O’Brien TJ and Kwan P. A mouse model of Alzheimer's disease displays increased susceptibility to kindling and seizure-associated death. Epilepsia. 2015; 56(6): e73-7. doi: 10.1111/epi.12993.