鐘世安

鐘世安，男，中共黨員，博士（後），中南大學教授，博士生導師，天然產物及藥物合成化學團隊負責人,“531人才工程”計畫資助。2008年留學澳大利亞昆士蘭大學，在《Chemistry - A European Journal》、《Polymer Degradationand Stability》、《Journal of hazard materials》、《Electrochimica Acta》、《Materials Science and Engineering: C》《Colloids and Surfaces B: Biointerfaces》等國內外SCI刊物上共發表論文120餘篇；出版教材5本，專著3本，申請國家發明專利30項，獲國家授權專利21項。

基本介紹

• 中文名：鐘世安
• 國籍：中國
• 職業：博士生導師
• 性別：男

人物經歷

1996-1999 中南工業大學化學系碩士研究生,獲碩士學位

1999-2002 中南大學化學化工學院博士研究生, 獲博士學位

2001-2003 中南大學化學化工學院講師

2003-2005 中南大學材料科學與工程學院參加博士後科研工作

2003-2008 中南大學化學化工學院副教授

2008-2009 澳大利亞昆士蘭大學留學

2011-現在 中南大學化學化工學院教授，博士生導師

研究方向

1、天然藥物化學

2、納米靶向性控釋藥物

3、現代分離科學與技術

4、高分子醫用材料

研究生招生方向

1、製藥工程 (碩士研究生、博士研究生招生）

2、生物化工(碩士研究生招生）

主要貢獻

在研課題

當前位置: 中文主頁 >> 科研項目

• [1] 國家自然科學基金：刺激-回響性分子印跡複合微球的組裝及其可控吸附與釋放性能研究，立項代碼：21276283
  
• [2] 國家自然科學基金：磁性埃洛石納米管聚合體系的組裝及對外循環腫瘤細胞的吸附與分離研究，立項代碼：21576295
  
• [3] 教育部留學歸國人員基金項目：可降解人工骨骼材料的設計與製備
  
• [4] 科技部科技攻關計畫項目：分子印跡技術分離純化藤茶中活性成分的研究
  
• [5] 2018年湖南省普通高校教學改革研究項目:(湘教通[2018]436號)，有機化學”開放式精品示範課程建設與實踐
  
• [6] 奇硒菌粉活性成分分離純化、結構表征及抗腫瘤活性研究
  
• [7] 益生元黑茶的研發及產業化研究
  
• [8] 金絲桃素的製備方法
  
• [9] 中藥複方泡足片的研發
  
• [10] 電熱式保健型熱敷鹽的研發
  

發明專利

申請國家發明專利30項，其中獲21項授權，以第一發明人的專利情況：

• [1] 薯蕷中分離提取薯蕷皂素、澱粉纖維素和黃色素的工藝，授權號：ZL 200610031158.0
  
• [2] 柑橘類果皮中果膠的提取與製備工藝，授權號：ZL200510032091
  
• [3] 一種山蒼籽核仁深加工及綜合利用工藝，授權號：ZL200810031868
  
• [4] 柚類青果、次果、果皮綜合利用的加工工藝，授權號：ZL200710035811
  
• [5] 基於氧化石墨烯犧牲材料製備表面分子印跡微球的方法及套用，授權號：ZL201610228706.2
  
• [6] 一種核殼結構的溫敏性磁性蛋白質印跡微球的製備方法及套用，授權號：ZL201510193366.X
  
• [7] 一種光智慧型化矽膠表面分子印跡微球及其製備方法，授權號：ZL201210505221.5
  
• [8] 一種埃洛石納米管藥物緩釋材料及其製備方法，授權號：ZL201510061065.1
  
• [9] 一種刺激回響型聚吡咯納米管靶向藥物載體及製備方法，授權號：201510974522.6
  
• [10] 玉竹的深加工及綜合利用工藝，授權號：ZL201110414997.1
  
• [11] 用藤茶製備楊梅素的方法和焦亞硫酸鹽的套用，授權號：ZL201310189757.5
  
• [12] 金絲桃素的合成方法，授權號：ZL201410380705.0
  
• [13] 製備對2,4-二氯苯氧乙酸具有特異性吸附的磁性埃洛石分子印跡聚合物的方法，授權號：ZL201310624108.3
  
• [14] 一種泡騰片的製備方法，授權號：ZL201610381965.9
  
• [15] 基於疏水羥基磷灰石納米穩定粒子的皮克林乳液聚合製備表面分子印跡微球的方法及套用，授權號：ZL 2016111297542
  
• [16] 一種2’-脫氧腺苷的合成方法，授權號：ZL 201610381965.9
  
• [17] 一種埃洛石納米管藥物載體及埃洛石納米管載體藥物的製備方法，授權號：ZL2017101991132
  

論文

共發表ESI等高水平論文120餘篇，近來以第一作者或通訊作者發表的部分代表性論文有：

1.Synthesis of Size-tunable Hollow Polypyrrole Nanostructures and Their Assembly into Folate Targeting and pH-responsive Anti-cancer Drug Delivery [J]. European: Chemistry - A European Journal, 2017, 68,17279-17289

2. Molecularly imprinted polymers based on zeolite imidazolate framework-8 for selective removal of 2,4-dichlorophenoxyacetic acid[J]. Colloids and Surfaces A-physicochemical and engineering aspects, 2019, 570 :244–250

3. An improved synthesis ofthe5‑HT1A receptor agonist Eptapirone free base[J]. Chemical Papers, 2019, DOI:10.1007/s11696-019-00685-1

4. Polymethacrylic acid encapsulated TiO2 nanotubes for sustained drug release and enhanced antibacterial activities[J]. New J. Chem. 2019, DOI: 10.1039/c8nj04568b

5. Molecularly imprinted polymers fabricated using Janus particle-stabilized Pickering emulsions and charged monomer polymerization[J]. New J. Chem., 2018, 42, 7355

6. Molecularly imprinted polymers fabricated via Pickering emulsions stabilized solely by food-grade casein colloidal nanoparticles for selective protein recognition [J]. Analytical and Bioanalytical Chemistry, 2018, 410:3133–3143

7.An effective and convenient synthesis of cordycepin from adenosine [J]. Chemical Papers, 10.1007/s11696-017-0

8.Assembling of stimuli-responsive tumor targeting polypyrrole nanotubes drug carrier system for controlled release[J]. Materials Science and Engineering: C , 2018, 89: 316~327

9.A Pt/TiO2 Nanotube Array Electrode for Glucose Detection and Its Photoelectrocatalysis Self-Cleaning Ability [J]. J. Electrochem. Soc, 2017, 164(2): B66-B73

10. Multifunctional Halloysite Nanotubes for Targeted Delivery and Controlled Release of Doxorubicin In-Vitro and In-Vivo Studies [J]. Nanotechnology, 2017, 28: 37-42

11. Nanoscale trifunctional bovine hemoglobin for fabricating molecularly imprinted polydopamine via Pickering emulsions-hydrogels polymerization [J]. Colloids and Surfaces B: Biointerfaces, 2017, 159C: 131-138

12. Hydrophilic surface molecularly imprinted naringin prepared via reverse atom transfer radical polymerization with excellent recognition ability in a pure aqueous phase [J]. RSC Advances, 2017, 7(45): 28082-28091

13. Interconnectivity of macroporous molecularly imprinted polymers fabricated by hydroxyapatite-stabilized Pickering High internal phase emulsions-hydrogels for the selective recognition of protein [J]. Colloids and Surfaces B: Biointerfaces, 2017, 155: 142-149

14. Combination of adsorption by functionalized halloysite nanotubes and encapsulation by polyelectrolyte coatings for sustained drug delivery [J]. RSC Advances, 2016, 6(59): 54463-54470

15. The synthesis of temperature-sensitive molecularly imprinted film on novel support beads and its application for bovine serum albumin separation [J]. Colloids and Surfaces A, 2016, 504: 367-375

16. Bio-inspired magnetic molecularly imprinted polymers based on Pickering emulsions for selective protein recognition [J]. NEW JOURNAL OF CHEMISTRY, 2016, 40(10): 8745-8752

17. Halloysite-based dopamine-imprinted polymer for selective protein capture [J]. JOURNAL OF SEPARATION SCIENCE, 2016, 39(12): 2431-2437

18. Graphene oxide as a sacrificial material for fabricating molecularly imprinted polymers via Pickering emulsion polymerization [J]. RSC ADVANCES, 2016, 6(78): 74654-74661

19. Functionalization of halloysite nanotubes by enlargement and hydrophobicity for sustained release of analgesic [J]. Colloids and Surfaces A, 2015, 487: 154-16

20. Fabrication and evaluation of protein imprinted polymer based on magnetic halloysite nanotubes [J]. RSC Advances, 2015, 2015(5): 61-68

21. One-step synthesis of boronic acid group modified silica particles by the aid of epoxy silanes [J]. Applied Surface Science, 2015, 351: 353–357

22. Water-compatible halloysite-imprinted polymer by Pickering emulsion polymerization for the selective recognition of herbicides [J]. Journal of Separation Science, 2015, 38: 1365

23. One-pot preparation of boronic acid and PEG bi-functionalized silica particles for separation and purification of catecholamine from rat serum [J]. New Journal of Chemistry, 2015, 39: 8848-8854

24. A novel molecularly imprinted materials based on magnetic halloysite nanotubes for rapid enrichment 2, 4- dichlorophenoxyacetic acid in water [J]. Journal of hazardous materials, 2014, 276: 58-65

25. A novel self-cleaning, non-enzymatic glucose sensor working under a very low applied potential based on a Pt nanoparticle-decorated TiO2 nanotube array electrode [J]. Electrochimica Acta,, 2014, 115: 269-276

26. Efficient conversion of myricetin from Ampelopsis grossedentata extracts and its purification by MIP- SPE [J]. Journal of Chromatography B, 2014, 945-946: 39-45

27. Preparation and characterization of molecularly imprinted organic–inorganic hybrid materials by sol–gel processing for selective recognition of ibuprofen [J]. Journal of sol-gel science and technology, 2013, 66(1): 59–67

28. Silica particles coated with azobenzene-containing photoresponsive molecule-imprinted skin layer [J]. Colloid and Polymer Science, 2013, 291(9): 92049–2059

29. Synthesis of novel photoresponsive molecularly imprinted polymer microspheres with special binding properties [J]. Journal of Applied Polymer Science, 2013, 130(15): 869-876

30. Design and computational simulation of stimuli-responsive polymer by sol-gel for selective recognition of (4-chloro-2-methylphenoxy)acetic acid [J]. Polymer international, 2012, 61: 1778–1785

31. Dendritic polymers based on poly(ethylene glycol)-co-poly(glycolic acid)-co-methacrylate and 2.0 G-polyamidoamine- metharylamide: Design, Characterization, and in vitro degradation, and drug release properties [J]. Polymer Degradationand Stability, 2012, 97: 234-241

32. Synthesis of molecularly imprinted organic-inorganic hybrid azobenzene materials by sol gels for radiation induced selective recognition of 2,4-Dichlorophenoxy- acetic acid [J]. Radiation Physical Chemistry, 2011, 80(2): 130-135

33. Computer Simulation and Preparation of Molecularly Imprinted Polymer Membranes with Chlorogenic Acid as Template [J]. Polymer international, 2011, 60: 592-598
　　

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