趙沛基

趙沛基，男，博士，雲南大學生命科學院研究員。

基本介紹

  • 中文名：趙沛基
  • 國籍：中國
  • 畢業院校：中國科學院昆明植物研究所
  • 學位/學歷：博士
  • 專業方向：微生物學
人物經歷,研究方向,主要論文,

人物經歷

  1. 1993.09 ~ 1997.07雲南大學生物系生物技術專業，獲理學學士學位；
2. 2001.09 ~ 2004.07 中國科學院昆明植物研究所，獲理學碩士學位；
3. 2005.09 ~ 2008.07中國科學院昆明植物研究所，獲理學博士學位；
4. 1997.07 ~ 2003.07 中國科學院昆明植物研究所，研究實習員；
5. 2003.07 ~ 2007.12中國科學院昆明植物研究所，助理研究員；
6. 2008.01 ~ 2016.04 中國科學院昆明植物研究所，副研究員；
7. 2012.09 ~ 2013.03 美國The University of Nebraska–Lincoln化學系, 訪問學者；
8. 2009.01碩士研究生導師；
9. 2016.5 ~ 2016.11, 雲南大學省部共建雲南生物資源保護與利用國家重點實驗室，副研究員；
10. 2016.12 ~ 至今, 雲南大學省部共建雲南生物資源保護與利用國家重點實驗室，研究員

研究方向

圍繞“微生物代謝產物生物合成”研究方向，運用天然產物化學、生化與分子生物學等學科知識與實驗技術，開展微生物次生代謝產物的發現、生物合成及其調控機制的研究：
1. 微生物來源活性天然產物的分離鑑定；
2. 活性天然產物的生物合成。

主要論文

  1. Pei-Ji Zhao*, Yan-Long Yang, Liangchen Du, Ji-Kai Liu, Ying Zeng*. Elucidating the biosynthetic pathway for vibralactone, a novel pancreatic lipase inhibitor with a fused bicyclic β-lactone. Angewandte Chemie - International Edition. 2013, 52 (8): 2298-2302.
  2. Yan Li, Pei-Ji Zhao,(Co-author) Qian-Jin Kang, Juan Ma, Lin-Quan Bai*, Zi-Xin Deng. Dual carbamoylations on the polyketide and glycosyl moiety by Asm21 result in extended ansamitocin biosynthesis.Chemistry & Biology. 2011, 18 (12): 1571-1580.
  3. Peiji Zhao, Linquan Bai*, Juan Ma, Ying Zeng, Lei Li, Yirong Zhang, Chunhua Lu, Huanqin Dai, Zhaoxian Wu, Yaoyao Li, Xuan Wu, Gang Chen, Xiaojiang Hao, Yuemao Shen*, Zixin Deng, Heinz G. Floss. Amide N-glycosylation by Asm25, an N-glycosyltransferase of ansamitocins. Chemistry & Biology. 2008, 15, 863-874.
  4. Yin-He Yang, Xiao-Li Fu, Liang-Qun Li, Ying Zeng, Cheng-Yun Li, Yi-Neng He, Pei-Ji Zhao*. Naphthomycins L−N, Ansamycin Antibiotics from Streptomyces sp. CS. Journal of Natural Products. 2012, 75, 1409-1413.
  5. Pei-Ji Zhao, Suo Gao, Li-Ming Fan, Jing-Lei Nie, Hong-Ping He, Ying Zeng, Yue-Mao Shen, Xiao-Jiang Hao*. Approach to the Biosynthesis of Atisine-type Diterpenoid Alkaloids.Journal of Natural Products.2009, 72(4): 645-659.
  6. Fei-Xue Yu, Zhe Li, Yao Chen, Yin-He Yang, Guo-Hong Li, Pei-Ji Zhao*. Four new steroids from the endophytic fungus Chaetomium sp. M453 derived of Chinese herbal medicine Huperzia serrata. Fitoterapia, 2017,117: 41–46.
  7. Fei-Xue Yu, Yao Chen, Yin-He Yang, Pei-Ji Zhao*. Four new dimeric spiro-azaplilone derivatives cochliodones E-H from the entophytic fungus Chaetomium sp. M336. Phytochemistry Letters, 2016, 16, 263-267.
  8. Jing Li, Jin Xie, Yin-He Yang, Xiao-Lian Li, Ying Zeng, Pei-Ji Zhao*. Pestalpolyols A–D, cytotoxic polyketides from Pestalotiopsis sp. cr013. Planta Medica, 2015, 81: 1285-1289.
  9. Yan-Mei Chen, Yin-He Yang, Xiao-Nian Li, Cheng Zou and Pei-Ji Zhao*. Diterpenoids from the Endophytic Fungus Botryosphaeria sp. P483 of the Chinese Herbal Medicine Huperzia serrate.Molecules. 2015, 20, 16924-16932.
  10. Jin Xie, Jing Li, Yin-He Yang, Yu-Hui Chen, Pei-Ji Zhao*. Two new ambuic acid analogs from Pestalotiopsis sp. cr013. Phytochemistry Letters, 2014, 10: 291-294.
  11. Juan Ma, Yue-Mao Shen, Ying Zeng, Pei-Ji Zhao*. Two New N-(O-Carbamoylglucopyranosyl)-N- dimethylansamitocins from Actinosynnema pretiosum. Helvetica Chimica Acta. 2012, 95(9):1630–1636.
  12. Jun-Tian Li, Xiao-Li Fu, Chun Tan, Ying Zeng, Qi Wang，Pei-Ji Zhao*. Two new chroman derivations from endophytic Penicillium sp. DCS523. Molecules. 2011, 16, 686-693.
  13. Xiao-Mei Zhang, Guo-Hong Li, Juan Ma, Ying Zeng, Wei-Guang Ma, Pei-Ji Zhao*. Endophytic fungus Trichothecium roseum LZ93 antagonizing pathogenic fungi In Vitro and its secondary metabolites. Journal of Microbiology. 2010, 48(6): 784-790.

相關詞條

熱門詞條

聯絡我們