程建軍，美國伊利諾伊大學芝加哥校區博士後。
基本介紹
- 中文名：程建軍
- 職業：博士後
- 畢業院校：美國伊利諾伊大學芝加哥校區
- 代表作品：Developing Serotonin 2C (5-HT2C) Receptor Agonists for the Treatment of CNS Disorders
個人簡介,研究內容,代表論文,
個人簡介
2001.09 – 2005.06，山東大學藥學院，藥學學士；
2005.09 – 2010.07，中國科學院上海藥物研究所，藥物化學博士（導師：楊玉社）；
2010.07 – 2013.10，上海匯倫生命科技有限公司，高級研究員、部門經理；
2013.11 – 2016.03，美國伊利諾伊大學芝加哥校區，博士後（導師：Alan P. Kozikowski）；
2016.03至今，上海科技大學iHuman研究所，Research Associate Professor 、PI。
研究內容
基於GPCR靶點的藥物設計、合成和開發。
代表論文
1. Cheng, J.; Giguere, P. M.; Schmerberg, C. M.; Pogorelov, V. M.; Rodriguiz, R. M.; Huang, X.-P.; Zhu, H.; McCorvy, J. D.; Wetsel, W. C.; Roth, B. L.; Kozikowski, A. P.* Further Advances in Optimizing (2-Phenylcyclopropyl)methylamines as Novel Serotonin 2C Agonists: Effects on Hyperlocomotion, Prepulse Inhibition, and Cognition Models. J Med Chem, 2016, 59, 578–591.
2. Cheng, J.; Kozikowski, A. P.* We Need 2C but Not 2B: Developing Serotonin 2C (5-HT2C) Receptor Agonists for the Treatment of CNS Disorders. ChemMedChem ,2015, 10, 1963–1967.
3. Cheng, J.; Giguere, P. M.; Onajole, O. K.; Lv, W.; Gaisin, A.; Gunosewoyo, H.; Schmerberg, C. M.; Pogorelov, V. M.; Rodriguiz, R. M.; Giulio Vistoli, G.; Wetsel, W. C.; Roth, B. L.; Kozikowski, A. P.* Optimization of 2-Phenylcyclopropylmethylamines as Selective Serotonin 2C Receptor Agonists and Their Evaluation as Potential Antipsychotic Agents. J Med Chem, 2015, 58, 1992–2002.
4. Cheng, J.; Giguere, P. M.; Lv, W.; Roth, B. L.; Kozikowski, A. P.* Design and Synthesis of (2-(5-Chloro-2,2-dimethyl-2,3-dihydrobenzofuran-7-yl)cyclopropyl)-methanamine as a Selective Serotonin 2C Agonist. Tetrahedron Lett, 2015, 56, 3420–3422.
5. Cheng, J.*; Qin, J.; Guo, S.; Qiu, H.; Zhong, Y. Design, Synthesis and Evaluation of Novel HDAC Inhibitors as Potential Antitumor Agents. Bioorg Med Chem Lett ,2014, 24, 4768–4772.
6. Cheng, J.; Liqiang Fu, L.; Chenyu Ling, C.; Yang, Y.* Total Synthesis of S-(–)-Stepholidine Using (S)-tert-Butanesulfinylimine. Heterocycles, 2010, 81, 2581–2592.
7. Cheng, J.-J.; Yang, Y.-S.* Enantioselective Total Synthesis of (–)-(S)-Stepholidine. J Org Chem, 2009, 74, 9225–9228.
