周樹堂(博士生導師)

周樹堂(博士生導師)

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周樹堂,男,博士研究員博士生導師中國科學院動物研究所昆蟲發育與生殖基因調控研究組組長。

基本介紹

人物簡介,主要成就,研究方向,出版著作,

人物簡介

1981-09-01—1985-06-30 河南農業大學 本科
1998-06-15—2002-12-30 加拿大Queen's University 博士
2002年畢業於加拿大Queen’s University,獲生物化學和分子生物學博士學位。2003-2004年在Queen’s University蛋白質功能中心和生物化學系從事博士後研究,2005年後在美國Duke University Medical Center任助理研究員、助理教授。2009年入選中國科學院“百人計畫”,2010年起擔任中國科學院動物研究所研究員、博士生導師、昆蟲發育與生殖基因調控研究組組長,2011年獲“百人計畫”擇優支持。
周樹堂

主要成就

長期從事發育生物學,轉錄調控機制,細胞因子與信號通路,功能基因進化及環境脅迫適應等方面的研究。曾獲美國PRS NIH/NICHD Young Investigator Award,擔任Journal of Allergy and Therapy編委。近年的研究成果發表於PNAS, Insect Biochemistry and Molecular Biology, Journal of Cell Science, American Journal of Physiology等SCI期刊上。授權國際專利1項。

研究方向

綜合運用分子生物學、生物化學細胞生物學等手段,研究昆蟲生殖發育與變態的基因調控機制,昆蟲與寄主植物的相互作用和昆蟲適應環境脅迫的分子機理。包括昆蟲激素(保幼激素、蛻皮激素、肽激素等)或環境與寄主因子誘導下的基因轉錄與調控、蛋白表達與修飾、信號傳導等。

出版著作

1、S. Zhou*, E.Potts, F. Cuttitta, W.M. Foster, and M.E. Sunday*. Gastrin-releasing peptide blockade: broad-spectrum anti-inflammatory therapy for asthma.* Co-corresponding authors. Submitted.
2、S. Zhou, S. Degan, E.N. Potts, W.M. Foster and M.E. Sunday. 2009. NPAS3 is a trachealess homolog critical for lung development and homeostasis. Proceeding of the National Academy of Science. 106, 11699–11704.
3、B.M. Levesque*, S. Zhou*, L. Shan, Y. Kong and M.E. Sunday. 2007. NPAS1 regulates branching morphogenesis in embryonic lung. American Journal of Respiratory Cell and Molecular Biology. 36, 427-434. * contributed equally as co-first authors
4、S. Zhou, M. Tejada, G.R. Wyatt, V.K. Walker. 2006. A DNA-binding protein, tfp1, involved in juvenile hormone-regulated gene expression in Locusta migratoria. Insect Biochemistry and Molecular Biology. 36: 724-734.
5、S. Zhou, B.A. Webb, R. Eves, and A.S. Mak. 2006. Effects of Tyr-phosphorylation of cortactin on podosome-formation in A7r5 vascular smooth muscle cells. AJP-Cell Physiology.290, C463-471.
6、B.A. Webb, S. Zhou, R. Eves, and A.S. Mak. 2006. Phosphorylation of cortactin by p21-activated kinase. Archives of Biochemistry Biophysics. 456, 183-193.
7、R. Eves, B.A. Webb, S. Zhou, and A.S. Mak. 2006. Caldesmon is an integral component of podosomes in smooth muscle cells. Journal of Cell Science. 119, 1691-1702.
8、B.A. Webb, R. Eves, S. Crawley, S. Zhou, G.P., Côté and A.S. Mak. 2005. p21-activated kinase induces podosome formation in A7r5 vascular smooth muscle cells in a PIX-dependent manner. AJP-Cell Physiology. 289: C898-907.
9、D.C. Hayward, T.S. Dhadialla, S. Zhou, M.J. Kuiper, E.E. Ball, G.R. Wyatt, V.K. Walker. 2003. Ligand specificity and developmental expression of RXR and ecdysone receptor in the migratory locust. Journal of Insect Physiology. 49, 1135-1144.
10、S. Zhou, J. Zhang, M. Hirai, Y. Chinzei, H. Kayser, G.R. Wyatt, V.K. Walker. 2002. A DNA-binding protein involved in gene regulation by juvenile hormone. Molecular and Cellular Endocrinology. 190, 177-185.
11、S. Zhou, J. Zhang, M.D. Fam, G.R. Wyatt, V.K. Walker. 2002. Sequences of elongation factors-1a and -1g and stimulation by juvenile hormone in Locusta migratoria. Insect Biochemistry and Molecular Biology. 32, 1567-1576.

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