2002年畢業於山東大學化學院，獲理學博士學位。2003-2005年在美國Louisiana State University 化學系做博士後從事卟啉、酞菁配合物光動力治療光敏劑的設計、合成及性能研究；2007-2009在美國University of Texas Southwestern Medical Center做博士後研究員從事大環金屬配合物癌症靶向生物探針的設計、合成及生物活性的研究；2009年7月回國，在山東大學晶體所任教授，碩士生導師。
研究方向
1、卟啉、酞菁癌症靶向光動力治療光敏劑及顯影劑的設計及生物性能測試
光動力治療（photodynamic therapy, PDT）是近幾十年來發展起來的一種癌症治療技術。該技術利用光激發癌細胞內部的光敏劑分子（photosensitizer ,PS）產生高細胞毒性的單線態氧從而在細胞內部殺死癌細胞，而使正常組免受傷害。它與手術、化療和放療等三大傳統的治療腫瘤手段相比，具有許多優點和特點。自上世紀70年代進入臨床研究以來，PDT在惡性腫瘤的治療中取得了令人矚目的成就，已成為腫瘤防治研究中的一個十分活躍的領域。它不僅能有效地治療體表腫瘤，同樣亦可治療呼吸道、胃腸道、顱腦、眼、膀胱等部位的腫瘤。美國、日本、荷蘭和加拿大等國的衛生部門已相繼確認了這一腫瘤新療法的合法性。PDT在治療非腫瘤疾病方面也得到了廣泛的重視，在不久的將來可能成為治療皮膚病、老年黃斑病變和白血病等頑疾的有效手段。作為PDT的光敏劑，卟啉 （Porphyrin, Por）及其衍生物酞菁（Phthalocyanine, Pc）一直以來發揮著領銜的作用。迄今，美國食品和醫藥管理局（Food and Drug Administration, FDA）唯一批准臨床套用於腫瘤治療的PDT光敏劑，Photofrin,就是一種血卟啉衍生物（HpD）的提純物，在美國用來治療食道癌和肺癌。在世界範圍內，Photofrin已經廣泛套用於治療各種惡性腫瘤並取得了很大成功。本課題旨在設計併合成出成分單一，高單線態氧產率、高選擇性的酞菁類光敏劑並進行相應的生物功能測試，為光動力治療開發新型、高效的癌症治療及顯影藥物。
2008 Conference Award from University of Texas Southwestern MedicalCenter USA
近期代表性論文
1. Dongmei Xu, Jing Qiao,‡ Nannan Wu,Wei Liu,*, Fenglong Wang, Longfei Lv, Jiabao Pan,Yazhuo Dong,§ and Jiurong Liu*,Facile Synthesis of Three-Dimensional Porous Co/MnO CompositesDerived from Bimetal Oxides for Highly Efficient ElectromagneticWave AbsorptionACS Sustainable Chem. Eng.2019, 7, 8687−8695
2.Kai Le, Zhou Wang, Fenglong Wang, Qi Wang, Qian Shao,Vignesh Murugadoss,Shide Wu,Wei Liu,*a Jiurong Liu, * Qiang Gao* and Zhanhu Guo *Sandwich-like NiCo layered double hydroxide reduced graphene oxide nanocomposite cathodes for high energy density asymmetric supercapacitorsDalton Trans.,2019, 48,5193
3.Jiabao Pan, Yang Yang, Wenjuan Fang,Wei Liu*, Kai Le, Dongmei Xu, and Xiangzhi Li*Fluorescent phthalocyanine−graphene conjugate with enhanced NIR absorbance for imaging and multi-modality therapyACS Appl. Nano Mater.2018,1, 2785−2795
4.Yuxing Ni , Kai Le, Wenjing Du, Wenjuan Fang, Xi Chen,Wei Liu,∗Yana Wang, Jiurong Liu.High response to nitrogen dioxide derived from antimony peroxide modified tin oxide porous nanocomposites serving as gas sensing materialSensors and Actuators B: Chemical2017,247,216–223
5.Wenjing Du, Nannan Wu, Zhou Wang, Jiurong Liu,∗Dongmei Xu,Wei LiuHigh response and selectivity of platinum modified tin oxide porous spheres for nitrogen dioxide gas sensing at low temperature.Sensors and Actuators B,2018257, 427–435
6.Song Qiu, Hailong Lyu, Jiurong Liu*, Yuzhen Liu, Nannan Wu, andWei Liu. Facile Synthesis of Porous Nickel/Carbon Composite Microspheres with Enhanced Electromagnetic Wave Absorption by Magnetic and Dielectric Losses.ACS Appl. Mater. Interfaces2016, 8, 20258−20266
7.Liqiang Luan, Wenjuan Fang,Wei Liu,* Minggang Tian, Yuxing Ni, Xi Chen and Xiaoqiang Yu.Phthalocyanine-cRGD conjugate: synthesis, photophysical properties and in vitro biological activity for targeting photodynamic therapy.Org. Biomol. Chem.,2016, 14, 2985–2992
8.Yuxiang Chen, Wenjuan Fang, Kang Wang*,Wei Liu, and Jianzhuang Jiang,*NonperipheralTetrakis(dibutylamino)phthalocyanines. New Types of 1,8,15,22-Tetrakis(substituted)phthalocyanine Isomers,Inorg. Chem.2016,55, 9289−9296.
9.Huili Cao, Xinzhen Wang, Hongbo Gu, Jiurong Liu,* Liqiang Luan,Wei Liu,*Yiran Wang and Zhanhu Guo*Carbon coated manganese monoxide octahedron negative-electrode for lithium-ion batteries with enhanced performance.RSC Adv., 2015, 5, 34566
10.Shimei Guo, Shenyu Wang, Nannan Wu, Jiurong Liu,* Yuxing Ni andWei Liu*Facile synthesis of porous Fe2TiO5 microparticulates serving as anode material with enhanced electrochemical performances.RSC Adv., 2015,5, 103767.
11.Liqiang Luan, Wenjuan Fang,Wei Liu*, nggang Tian, Yuxing Ni, Xi Chen, Xiaoqiang Yu, Jing He, Yang Yang and Xiangzhi Li. 4-tert-Butylphenoxy substituted phthalocyanine with RGD motif as highly selective one-photon and two-photon imaging probe for mitochondria and cancer cell,Journal of Porphyrins and Phthalocyanines,2016, 20: 397–406.
12.Guiyang Hao，Wei Liu，Gedaa Hassan，Orhan K. Öz，Zoltan Kovacs Xiankai Sun*A comparative study of trans- and cis-isomers of a bone-seeking agent, DO2A2P.Bioorg.& Med. Chem. Lett.2015, 25，571–574.
13.Shimei Guo, Jiurong Liu,* Song Qiu,Wei Liu,*Yiran Wang, Nannan Wu, Jiang Guo and Zhanhu Guo.Porous ternary TiO2/MnTiO3@C hybrid microspheres as anode materials with enhanced electrochemical performances.J. Mater. Chem. A,2015, 3, 23895
14.Jiawei Shi, Liqiang Luan, Wenjuan Fang, Tianyu Zhao,Wei Liu*, Deliang Cui. High-sensitive low-temperature NO2sensor based on Zn(II) phthalocyanine with liquid crystalline properties.Sensors and Actuators B2014,204, 218–223.
15.Liqiang Luan, Lanlan Ding, Jiawei Shi, Wenjuan Fang, Yuxing Ni,Wei Liu*Effect of Axial Ligands on the Molecular Configurations, Stability, Reactivity and Photodynamic Activities of Silicon Phthalocyanines.Chem. Asian J. 2014,9，3491-3497.
16.Xinzhen Wang, Song Qiu, Guixia Lu, Cuizhu He, Jiurong Liu,* Liqiang Luan andWei Liu*Fabrication of porous MnO microspheres with carbon coating for lithium ion battery application.CrystEngComm, 2014, 16, 1802–1809
17.Ding Lanlan, Luan Liqiang, Jiawei Shi,Wei Liu*. Phthalocyanine Based Photosensitizers for Photodynamic Therapy.Chinese Journal of Inorganic Chemistry.2013, 29, 1591-1598.
18.Liqiang Luan, Lanlan Ding, Weijia Zhang, Jiawei Shi, Xiaoqiang Yu,Wei Liu*. A Naphthalocyanine Based Near-Infrared Photosensitizer: Synthesis and In Vitro Photodynamic Activities.Bioorg. & Med. Chem. Lett.2013, 23，3775-3779.
19.Xinzhen Wang,Wei Liu,Jiurong Liu*,Fenglong Wang,Jing Kong,Song Qiu,Cuizhu He, andLiqiang Luan.Synthesis of Nestlike ZnO Hierarchically Porous Structures and Analysis of Their Gas Sensing Properties.ACS Appl. Mater. Interfaces,2012,4(2), 817–825
20.Cuizhu He, Song Qiu, Xinzhen Wang, Jiurong Liu,* Liqiang Luan,Wei Liu*,Masahiro Itoh and Ken-ichi Machida. Facile synthesis of hollow porous cobalt spheres and their enhanced electromagnetic properties.J. Mater. Chem.,2012,22, 22160
Jing Kong，Wei Liu*, FenglongWang, XinzhenWang, LiqiangLuan, JiurongLiu , YuanWang, Zijun Zhang , MasahiroItoh , Ken-ichiMachida. Fabrication of monodispersed nickel flower-like architectures via a solvent-thermal process and analysis of their magnetic and electromagnetic properties.Journal of Solid State Chemistry,2011, 184, 2994–3001
Ajay N. Singh,Wei Liu, Guiyang Hao, Amit Kumar, Anjali Gupta, Orhan K.Oz, Jer-Tsong Hsieh, and Xiankai Sun.Multivalent Bifunctional Chelator Scaffolds for Gallium-68 Based Positron Emission Tomography Imaging Probe Design: Signal Amplification via Multivalency.Bioconjugate Chem.,2011,22(8), 1650–1662
Jian Zhou,Wei Liu, Rey-Chen Pong, Guiyang Hao and XiankaiSun et.al. Analysis of Oligo-arginine Cell-permeable Peptides Uptake by Prostate Cells.Amino Acid，2012, 42, 1253-60
Hao, Guiyang; Singh, Ajay N.;Liu, Wei; Sun, Xiankai. PET with Non-standard Nuclides.Current Topics in Medicinal Chemistry,2010, 10, 1096-1112.
Liu, Wei; Hao, Guiyang; Long, Michael A.; Anthony, Tiffani; Hsieh, Jer-Tsong; Sun, Xiankai*. Imparting Multivalency to a Bifunctional Chelator: A Scaffold Design for Targeted PET Imaging Probes.Angewandte Chemie, International Edition,2009, 48, 7346-7349
