neuraminidase

neuraminidase，英語單詞，主要用作名詞。作名詞時意為“神經氨酸苷酶；唾液酸苷酶”等。

基本介紹

• 外文名：neuraminidase
• 詞性：名詞
• 發音：njʊrəˈmɪnɪˌdes

單詞釋義

英 [ˌnjʊərəˈmɪnɪdeɪz] 美 [ˌnʊrəˈmɪnɪˌdes; ˌnʊrəˈmɪnɪˌdez; ˌnjʊrəˈmɪnɪˌdes]

n. [生化] 神經氨酸苷酶，[生化] 唾液酸苷酶

短語搭配

neuraminidase inhibitors 神經氨酸酶抑制劑 ; 抑制劑 ; 酶抑制劑

Neuraminidase Inhibitor 神經氨酸酶抑制劑 ; 神經胺酶抑制劑 ; 神經氨酸

Neuraminidase NA 神經氨酸酶

neuraminidase gene 神經氨酸酶基因

neuraminidase from vibrio cholerae 神經氨酸酶

influenza virus neuraminidase inhibitors 流感神經氨酸酶抑制劑

neuraminidase assay 神經氨酸酶測定

Neuraminidase from Clostridium perfringens 神經氨酸酶

雙語例句

• This epitope is sensitive to neuraminidase, but insensitive to protease. 這一抗原決定簇對神經氨(糖)酸苷酶敏感，但對蛋白酶不敏感。
• The H5N1 virus is expected to be susceptible to the neuraminidase inhibitors. H5N1病毒預期對神經氨酸酶抑制劑敏感。
• The next big target is another surface protein, neuraminidase (see "Moving target"). 其次是另一種表面蛋白神經氨酸酶（見 “轉移攻擊 ” ）。
• Simultaneously, physician should pay attention to the resistance of neuraminidase inhibitor. 同時提醒關注神經氨酸酶抑制劑套用的耐藥問題。
• M6 gold complexes showed no ability to bind to surface of erythrocytes treated by trypsin or neuraminidase. M6的膠體金複合物不能與經胰酶和神經氨酸酶處理過的紅細胞發生結合。
• Objective: to select the peptide binding to influenza virus neuraminidase from phage display 12 peptide library. 目的：從噬菌體呈現12肽庫中篩選與流感病毒神經氨酸酶特異性結合的肽。
• It codes for the neuraminidase enzyme - the N1 in H1N1 - which controls the expansion of the virus from infected cells. 因為其指定的神經氨酸酶遺傳密碼——H 1 N 1中的N1——控制著被感染細胞的病毒擴散。
• Neuraminidase (NA) is an important protein on the surface of virion and plays an important role in immune and lethality. 神經氨酸酶（NA）是流感病毒表面的一種重要蛋白質，在免疫和致病方面起重要作用。
• The viruses showed no mutations associated with resistance to the neuraminidase inhibitors, including oseltamivir (Tamiflu). 這些病毒顯示沒有與包括奧斯他韋(達菲)在內的神經氨酶抑制劑耐藥性有關的突變。
• CONCLUSION Pyrrolidine derivatives exhibited potent neuraminidase inhibitory activities, and is worth of further investigation. 結論吡咯烷類化合物對神經氨酸酶有較高的抑制活性，值得進一步研究。
• The virus that was currently detected in the us and Mexico is susceptible to neuraminidase inhibitors but resistant to amantadanes. 但是，近期在美國和墨西哥發現的病毒對抑制劑很敏感，卻對amantadanes有抵抗力。
• To overcome drug resistance, researchers are searching for alternative sites on neuraminidase against which new drugs can be targeted. 為了克服耐藥性，科學家正在神經氨酸酶上尋找一個替代的位置，並針對其開發新藥。
• The efficacy of the neuraminidase inhibitors depends, among others, on their early administration (within 48 hours after symptom onset). 神經氨酸酶抑制劑的療效特別取決於其早期使用(在症狀出現後48小時之內)。
• The agglutination test showed that PNA agglutinates neuraminidase-treated erythrocytes, thymocytes, and acute lymphatic leukemia cells. 凝集試驗表明PNA能凝集NA處理的紅細胞、胸腺細胞及急性淋巴細胞性白血病細胞；
• Zanamivir and oseltamivir bind differently at the neuraminidase catalytic site and this contributes to different drug resistance profiles. 扎那米韋和奧塞·米韋結合在神經氨酸酶的不同催化位點，這就導致了這種耐藥情況不同的發生。
• These drugs act against an enzyme called neuraminidase, which allows newly formed viruses to leave infected cells and spread around the body. 這些藥物抑制一種叫做神經氨酸酐酶的酶，這種酶可以促使新生成的病毒離開被感染的細胞向周身散播。
• Rats received two intravenous injections of either heparinase III to digest HS or neuraminidase to remove neuraminic acids (positive control). 實驗大鼠接受兩次肝素酶III注射以消化HS，或兩次神經氨酸酶注射以除去神經氨酸（陽性對照）。
• OBJECTIVE To synthesize a series of novel pyrrolidine derivatives as neuraminidase inhibitors and test their inhibitory activities against neuraminidase. 目的合成新型吡咯烷類神經氨酸酶抑制劑，並測定其抑制神經氨酸酶的活性。
• After the virus infects the cells of the respiratory system and begins replicating, neuraminidase cuts the newly formed copies free to invade other cells. 呼吸系統內的細胞染上病毒，而且病毒開始複製之後，神經氨酸酵素會將新生的病毒切下以便侵犯其他細胞。
• Antiviral resistance to neuraminidase inhibitors has been clinically negligible so far but is likely to be detected during widespread use during a pandemic. 到目前為止，對神經氨酸酶抑制劑的抗病毒製劑耐藥性，在臨床上很微弱，但在大流行期間廣泛使用這類抑制劑時可能會出現。
• There are two classes of such medicines, 1) adamantanes (amantadine and remantadine), and 2) inhibitors of influenza neuraminidase (oseltamivir and zanamivir). 這種藥物有兩類：1）烷胺類藥物（金剛烷胺和金剛乙胺），2）流感的神經氨酸酶抑制劑（奧司他韋和扎那米韋）。
• For the neuraminidase inhibitors, the main constraints - which are substantial - involve limited production capacity and a price that is prohibitively high for many countries. 就神經氨酸酶抑制劑而言，有一些重大的限制因素，主要是生產能力有限，同時，在許多國家，其價格高得難以負擔。
• The result show that, neuraminidase is one of the main immune protective antigen for the Hps, which provides a theoretical basis for further study of the Hps subunit vaccine. 結果表明神經氨酸酶是Hps的主要免疫保護性抗原之一，為進一步研究Hps亞單位疫苗提供理論依據。
• The virus strain was identified Avian Influenza virus a, the sub-serotypes of hemagglutinin (ha) and neuraminidase (NA) were not determined. And the strain had excellent immunogenicity. 經血清學鑑定為A型禽流感病毒(HA、NA亞型未測定)，該病毒株具有良好的免疫原性。
• Acetylneuraminic acid, the substrate of neuraminidase, which display a inhibitory effects on neuraminidase, has a close relationship with the infection and spread of many kinds of virus. 而唾液酸是唾液酸苷酶的底物，對唾液酸苷酶具有抑制作用，與很多種病毒的感染和傳播關係密切。
• METHODS a series of pyrrolidine derivatives were synthesized from L-hydroxyproline, and the neuraminidase inhibitory activities of these compounds were tested using high throughput screening. 方法以L -羥脯氨酸為原料，合成一系列神經氨酸酶抑制劑，並用高通量活性篩選方法檢測其對神經氨酸酶的抑制活性。