Trypsin(胰蛋白酶)是英語名詞,音標為/ˈtrɪp.sɪn/,指脊椎動物胰腺分泌的絲氨酸蛋白酶,功能為催化蛋白質水解為小肽,以酶原形態(trypsinogen)分泌,經腸道激活後參與消化。該酶具有底物特異性,選擇性切割精氨酸或賴氨酸羧基端的肽鍵,其抑制劑(如大豆胰蛋白酶抑制劑)在生物醫學領域有重要研究價值。
1876年德國生理學家威廉·屈內首次分離並命名該酶。20世紀研究發現其通過激活消化酶級聯反應維持蛋白質代謝,並在病毒複製、腫瘤轉移中起調控作用。現代生物技術中廣泛用於細胞培養的組織消解,其結晶形態(trypsin crystallized)及外用製劑(trypsin for external use)已套用於臨床與實驗室。
基本介紹
- 外文名:trypsin
- 詞性:名詞
- 英式發音:['trɪpsɪn]
- 美式發音:[ˈtrɪpsɪn]
單詞釋義
單詞用法
短語搭配
雙語例句
- Decellularized porcine heart valves were prepared by using Trypsin-ethylenediamine tetraacetic acid and DNase. 利用胰酶-乙二胺四乙酸、核酸酶處理豬心瓣膜製備脫細胞支架。
- The activity of bovine trypsin is less influenced by tween. 吐溫對牛胰蛋白酶活性的影響較少。
- The enzyme was a kind of serine protease with trypsin - like activity. 此酶屬絲氨酸蛋白酶類,胰蛋白酶類。
- Objective To establish PCR assay of Porcine Parvovirus detection in Trypsin. 目的建立原材料胰蛋白酶中豬細小病毒的PCR檢測方法。
- C Trypsin Inhibitor - This negative compound reduces your ability to digest protein. 胰蛋白酶抑制劑-這種消極的複合降低您的能力去消化蛋白質。
- The inhibitory activity is influenced by treatment with trypsin, pepsin and proteinase K. 用蛋白酶處理,其抑菌活性受胰蛋白酶、胃蛋白酶和蛋白酶K的影響;
- This paper researched a method of heat treating to inactivate trypsin in dolichos lablab. 該文主要研究熱處理鈍化扁豆液中胰蛋白酶抑制子的方法。
- The inhibitory activity was influenced by treatment with trypsin, pepsin and proteinase K. 用蛋白酶處理,其抑菌活性受胰蛋白酶、胃蛋白酶和蛋白酶K的影響;
- The technique for bio-liquefaction of black-bone chicken was studied with porcine trypsin. 採用豬胰臟作為胰酶的主要來源,對烏雞的酶解工藝進行了研究。
- Toxins were activated by trypsin to mimic the protease activation that occurs in the insect gut. 用胰蛋白酶激活毒素來模仿在昆蟲腸道蛋白酶激活發生。
- The aim of the paper was to study the inactivation of soybean trypsin inhibitor by ferrisulphas. 文章的目的在於研究硫酸亞鐵對大豆胰蛋白酶抑制劑的鈍化作用。
- M6 gold complexes showed no ability to bind to surface of erythrocytes treated by trypsin or neuraminidase. M6的膠體金複合物不能與經胰酶和神經氨酸酶處理過的紅細胞發生結合。
- The resulting product shows powerful trypsin inhibitory activity that near 97% of the activity of natural HTI. 合成品對牛胰酶有很強的抑制能力,其活性約為天然產物的97%。
- Results Porcine skin fibroblast line was established and the tissue piece method was superior to trypsin methods. 結果建立了豬皮膚成纖維細胞系組織塊培養法優於胰酶法。
- Trypsin was immobilized on the Mesoporous Molecular Sieve MCM-41 with the aid of the coupling agent, glutaraldehyde. 以介孔分子篩m CM - 41作為載體,戊二醛作為交聯劑,對胰蛋白酶進行了固定化。
- Conclusion: Trypsin enzymic digestion and differential attachment was suitable for culture of ventricular fibroblast. 結論:胰酶消化、差速貼壁法是一種適合的心室成纖維細胞的培養方法。
- The aim of this paper is to prepare magnetic particle of crosslinked Alginate Sodium and to apply it to immobilize Trypsin. 本文的目的是製備交聯海藻酸鈉磁性微球,並用於固定化胰蛋白酶。
- The results showed that all the preparations from the larval intestines contained chymotrypsin-like and trypsin-like enzymes. 結果表明:三種幼蟲腸道都含有類胰凝乳蛋白酶和類胰蛋白酶。
- To hydrolyze the sea cucumber collagen, four proteases are used as follows:3942 neutral proteinase, trypsin, papain, bromelain. 本實驗選用3942中性蛋白酶、胰蛋白酶、木瓜蛋白酶、鳳梨蛋白酶四種酶對膠原蛋白進行水解。
- AIM: Aqueous extract from Chinese nutgall was tested for its ability to inhibit trypsin-like activity produced by P. gingivalis. 目的:觀察五倍子水提取物對牙齦卟啉單胞菌胰酶樣蛋白酶活性的影響。
- Methods: The effect of conjugated bile acids on the rate of protein hydrolysis by trypsin and chymotrypsin was examined in vitro. 方法:體外實驗檢測結合膽汁酸對胰蛋白酶和糜蛋白酶水解蛋白速率的影響。
- Comparative study on preparation of phosphopeptide from yolk protein and casein hydrolyzed by trypsin was conducted in this paper. 對用胰酶水解酪蛋白和蛋黃蛋白製備磷酸肽進行了比較研究。
- Trypsin and flavorzyme were regarded as the compound enzyme in comparison with hydrolysis rate and bitterness value of other proteinase. 通過對蛋白酶水解度和苦味值的比較,確定了胰蛋白酶和複合風味蛋白酶作為復配酶。
- No putative trypsin hydrolysis site was found in C peptide, however, 4 and 3 potential sites were found in A and B peptides respectively. 胰蛋白酶水解位點分析表明C肽無裂解位點,而A肽和B肽則分別具有3個和4個潛在水解位點。
- Pancreatitis is activated by trypsin-induced pancreatic tissue inflammation caused by their own digestion, and is also a clinical Common. 胰腺炎是由胰酶激活後引起的胰腺組織自身消化所致炎症,亦是一種臨床常見病。
- The recycled reversed micelles were reused and the results show total extraction rate is 19.8% and trypsin specific activity is 2.8 times. 將回收的反膠束再次用於萃取試驗,胰蛋白酶總萃取率達到19.8%,比活力純化倍數為2.8。
- Trypsin was modified by a series of PEG derivatives, then the properties of modified enzymes were evaluated and were compared with native enzyme. 採用各種類型的聚乙二醇衍生物修飾胰蛋白酶,對所修飾酶的酶學性質進行了評價並與原酶比較。

