基本介紹
- 中文名：黃行許
- 外文名：Huang X
- 職業：教授
- 畢業院校：江西農業大學
- 代表作品：Efficient genome modification in mice by CRISPR/Cas9 nickase without off-target effects
研究內容,代表論文,
研究內容
研發特異性調節轉錄因子功能性反應元件以及表觀遺傳修飾的策略，並以此揭示配子發生過程中的轉錄和表觀遺傳修飾調節的機制及其生物學意義。
代表論文
Wang L, Zhang J, Duan J, Gao X, Zhu W, Song C, Yang L, Zhang J, Li G, Ci W, Li W, Zhou Q, Tang F, He C, Huang X*, Liu J*. Programming and inheritance of parental DNA methylome in mammal. Cell 2014, 157(4): 979-991.
Shen B, Zhang J, Zhang W, Zhou J, Wang J, Chen L, Wang L, Hogkins A, Iyer V, Huang X*, Skarnes W*. Efficient genome modification in mice by CRISPR/Cas9 nickase without off-target effects. Nature Methods 2014, 11(4): 399-402.
Niu Y, Shen B, Cui Y, Chen Y, Wang J, Wang L, Kang Y, Zhao X, Si W, Li W, Xiang AP, Zhou J, Guo X, Si C, Hu B, Dong G, Wang H, Zhou Z, Li T, Tan T, Pu X, Wang F, Ji S, Zhou Q, Huang X*, Ji W*, Sha J*. Generation of gene-modified cynomolgus monkey via Cas9/RNA-mediated gene targeting in one-cell embryos. Cell 2014, 156(4): 836-843. (Comment in: Science 2014, 343: 476-477. Nature 2014, 506: 8-8.) (This paper is on the recommended list at facultyof1000.com) (Selected by Nature as one of the events in the years in sciences: Wins and Losses) (Selected by Cell as one of the 10 Best articles in 2014).
Ma Y, Zhang X, Shen B, Lu Y, Chen W, Ma J, Bai L, Huang X*, Zhang L*. Generating rats with conditional alleles using CRISPR/Cas9. Cell Research 2014, 24(1): 122-125.
Shen B, Zhang J, Wu H, Wang J, Ma K, Li Z, Zhang X, Zhang P, Huang X*. Mouse gene knockout by Cas9/RNA-mediated site-specific gene targeting. Cell Research 2013, 23(5): 720-723.
