靜息張力

考察用靜息張力表征離體蟾蜍腓腸肌等長收縮能力的有效性。

基本介紹

  • 中文名:靜息張力
  • 有效性等長收縮能力
  • 目的:反映肌肉收縮能力
  • 實驗對象:體蟾蜍腓腸肌
操作方法,英文翻譯,關鍵字,

操作方法

SOD抑制劑和維生素C聯合作用蟾蜍腓腸肌,記錄電刺激(12VDC,2ms波寬,2s間隔)下等長收縮張力變化,單指數函式加權擬合90%峰張力後的鬆弛過程測定鬆弛速度和靜息張力表徵收縮能力。結果 收縮1.0min後對照靜息張力在7.0min內單調下降而藥物處理後靜息張力先降後升,7.0min後處理組靜息張力相對初始值的增加值顯著高於對照組。同時,對照鬆弛速度大多單調下降,藥物處理後鬆弛速度多數先升後降,且10.0min內其鬆弛速度總低於相同時刻的對照組。結論 靜息張力可反映肌肉收縮能力。

英文翻譯

ObjectiveTocharacterizetheisometriccontractilityofBufogastrocnemiusexvivoinlightoftheresttension.MethodsBufogastrocnemiustreatedwithSODinhibitorandascorbatewasstimulatedelectrically(12VDC,2msdurationwitha2sinterval)torecordthetensionwithin10min.Weightedfittingtotherelaxationcurveofthetensionbelow90%ofthepeaktensionwithamono-exponentialmodelyieldedtheresttensionandrelaxationrate.ResultsThecontrolgastrocnemiusshowedmonotonicdecreaseoftheresttension,buttreatmentwithSODinhibitorandascorbateresultedinadecreaseoftheresttensionfollowedbyafastincreasewithina1.0mincontraction.Theincreaseoftheresttensionat7.0minofcontractionofthetreatedmusclewassignificantlygreaterthanthatofthecontrolmuscle.Thecontrolmuscleshowedamonotonicdecreaseoftherelaxationratein10min,whereastreatmentwithSODinhibitorandascorbateproducedincreasedrelaxationratefollowedbymonotonicdecreasetillaplateauwasreached.Inthecourseofthe10minrecording,therelaxationrateofthetreatedmusclewaslowerthanthatofthecontrolafterthesamedurationofcontraction.ConclusionResttensionisacharacteristicindextorepresenttheskeletalmusclecontractility.

關鍵字

蟾蜍腓腸肌,等長收縮能力,肌肉損傷,靜息張力,鬆弛速度;Bufogastrocnemius,isometriccontractility,muscledamage,resttension,relaxationrate

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