1998-2006年:先後主持承擔了20餘項科研項目,其中國家自然科學基金5項(批准號為39770539、30100131、30571328、30671138、U0631005):4個國家基金面上項目和1項重點項目,1項“十一五”“863”課題,2項國際科學基金(International Foundation for Science, IFS,課題編號:B2580/1,B2580/2)、1項國際原子能機構項目。作為主要學術骨幹參與承擔了“973”項目“農業動物遺傳資源的分子標記評估及其優質基因的分離和利用研究”(2001-2005)、“重要複雜性狀的比較基因組”(2006-2008)的研究工作。
(5)2005年9 月被邀請出席在哈爾濱召開的黑龍江國際生物技術峰會(International Agro-Biotechnology Conference, Heilongjiang, China ),並在大會上作題為“Transcriptional profiling in the pig using oligonucleotide microarrays”的特邀報告。
(7)2005年1月出席在美國聖地亞哥召開的第十三次國際動植物基因組會議(Plant & Animal Genome XIII Conference),並在分會上作題為“Transcriptional profiling in normal tissues and Salmonella choleraesuis infected lung using the porcine 70mer oligo array”的報告。
(8)2004年1月出席在美國聖地亞哥召開的第十二次國際動植物基因組會議(Plant & Animal Genome XII Conference),並作牆報展示。
(9)2003年1月出席在美國聖地亞哥召開的第十一次國際動植物基因組會議(Plant & Animal Genome XI Conference),並作牆報展示。
5)Sequence, polymorphisms, and marker test technology for disease resistance (NFKB1), Application no. 60660124 (美國)。完成人: Christopher K Tuggle, Zhao Shuhong (趙書紅),Marnie Mellencamp,John Bastiaansen, Lucina Galina
發表論文
1) Ma Guojian, Huang Jing, Sun Nunu, Zhu Mengjin, Wu Zhenfang, Zhao Shuhong(通訊作者), Molecular characterization of porcine GBP1 and GBP2 genes. Molecular Immunology, 2008, doi:10.106/J.molimm (Eu ahead of print). IF = 4.768
2) Zhao SH, Recknor J, Lunney JK, Nettleton D, Kuhar D, Orley S, Tuggle CK. Validation of a first-generation long-oligonucleotide microarray for transcriptional profiling in the pig. Genomics. 2005, 86(5):618-25. IF =3.558
3) Ting-Hua Huang, Bin Fan, Max F. Rothschild, Zhi-Liang Hu, Kui Li, Shu-Hong Zhao(通訊作者), MiRFinder: An improved approach and software Implementation for genome-wide fast microRNA precursor scan, BMC bioinformatics, 2007 Sep 17;8(1):341. IF = 3.617
4) Zhengmao Zhu, Yong Li, Delin Mo, Kui Li and Shuhong Zhao(通訊作者). Molecular characterization and expression analysis of the porcine caveolin-3 gene. Biochemical and Biophysical Research Communications,2006, 346: 7-13IF = 2.855
5) Shu-Hong Zhao, Daniel Kuhar, Joan K. Lunney, Harry Dawson, Catherine Guidry, Jolita J. Uthe, Shawn M. D. Bearson, Justin Recknor, Dan Nettleton, Christopher K. Tuggle. Gene expression profiling in Salmonella Choleraesuis infected porcine lung using a long oligonucleotide microarray. Mammalian Genome. 2006, 17: 777-89 IF = 2.279
6) Zhao SH, Simmons DG, Cross JC, Scheetz TE, Casavant TL, Soares MB, Tuggle CK, PLET1 (C11orf34), a highly expressed and processed novel gene in pig and mouse placenta, is transcribed but poorly spliced in human.Genomics. 2004, 84(1): 114-25. IF =3.558
7) Feng Z, Tang ZL, Li K, Liu B, Yu M, Zhao SH (通訊作者). Molecular characterization of the BTG2 and BTG3 genes in fetal muscle development of pigs. Gene. 2007 Nov 15;403(1-2):170-177. IF =2.721
8) Zhu Z M, Zhang J B, Li K, Zhao S H(通訊作者). Cloning, mapping and association study with carcass traits of the porcine SDHD gene. Animal Genetics. 2005, 36, 191-195. IF =1.520
9) S.-H. Zhao, D. Nettleton, W. Liu, C. Fitzsimmons, C.W. Ernst,N. E. Raney, and C. K. Tuggle*,Complementary DNA macroarray analyses of differential gene expression in porcine fetal and postnatal muscle.Journal of Animal Science. 2003. 81:2179–2188 IF =1.983
10) Zhou QY, Huang JN, Xiong YZ, Zhao SH (通訊作者). Imprinting analyses of the porcine GATM and PEG10 genes in placentas on days 75 and 90 of gestation. Genes and Genetic Systems, 2007, 82:265-9.
11) Feng Y, Huang TH, Fan B, Zhao SH (通訊作者). Mapping of six miRNAs expressed in porcine skeletal muscle. Anim. Genet. 2008, 39:91-92
12) Qiu H,Zhao S, Yu M, Fan B, Liu B.Expression patterns and subcellular localization of porcine (Sus Scrofa) lectin, galactose-binding, soluble 1 gene. Acta Biochim Biophys Sin. 2008, 40(1):85-90.
13) Jing Yu, Quanyong Zhou, Mengjin Zhu, Changchun Li, Bang Liu, Bin Fan,Shu-Hong Zhao(通訊作者). The Porcine FoxO1, FoxO3a and FoxO4 Genes: Cloning, Mapping, Expression and Association Analysis with Meat Production Traits. Asian-Australasian Journal of Animal Sciences, 2007, 20: 627-633
14) Feng Z, Zhou QY, Ma GJ, Li K, Zhao SH (通訊作者). Mapping of porcine BTG1, BTG4, TOB2, USP2 and PEG3 using somatic cell and radiation hybrid panels. Anim Genet. 2007 Oct;38 (5):536-7.
15) Zhu M,Zhao S (通訊作者). Candidate Gene Identification Approach: Progress and Challenges. Int J Biol Sci 2007; 3:420-427.
16) Chen-Chang XU, Quan-Yong ZHOU, Li-Jie SU, Chang-Chun LI, Shu-Hong ZHAO, Imprinting Analysis of the MEST Gene in 75 and 90 Day Placentas and Prenatal Porcine Tissues, Acta Biochimica et Biophysica Sinica, 2007, Aug;39(8):633-9.
17) Jing Huang, Zheng-Mao Zhu, Shu-Hong Zhao (通訊作者)SNP detection, Imprinting, and Expression analysis in prenatal skeletal muscle of the Porcine Succinate Dehydrogenase Complex, Subunit D (SDHD) Gene. Research Journal of Animal Science, 2007, 1: 102-106
18) Li X, Zhu Z, Mo D, Wang H, Yang S, Zhao S, Li K. Comparative molecular characterization of ADSS1 and ADSS2 genes in pig (Sus scrofa). Comp Biochem Physiol B Biochem Mol Biol. 2007 Feb 1; [Epub ahead of print]
19) Tang Z, Li Y, Wan P, Li X, Zhao S,Liu B, Fan B, Zhu M, Yu M, Li K. LongSAGE analysis of skeletal muscle at three prenatal stages in Tongcheng and Landrace pigs. Genome Biology, 2007,8::R115
20) Uthe JJ, Royaee A, Lunney JK, Stabel TJ, Zhao SH, Tuggle CK, Bearson SM. Porcine differential gene expression in response to Salmonella enterica serovars Choleraesuis and Typhimurium. Molecular Immunology, 2007 Mar 2; [Epub ahead of print]
21) LIU, K.; ZHAO, S.; LIU, B.; BIN FAN, B.; LI, CH; YU, M. Assignment of solute carrier family 2 (facilitated glucose transporter), members SLC2A2, SLC2A3, SLC2A5, SLC2A8 and SLC2A12 to porcine chromosomes by somatic cell and radiation hybrid panel mapping. Archives of Animal Breeding, 2007, 50: 114-115
22) H. F. Qiu, X. W. Xu, S. H. Zhao, B. Fan, M. Yerle and B. Liu. Somatic cell hybrid and RH mapping of the porcine LGALS1, ITGA7, ITGB1, LGALS3, NOL12, GGA1, SH3BP1 and PDXP genes. Animal Genetics, 2007. 38 (3): 315-316.
30) Tang Zhong-Lin, Li Yong, Zhao Shu-Hong, Liu Bang, Fan Bin and Li Kui. 農業生物技術學報(Chinese Journal of Agricultural Biotechnology) , 2007, 4: 111-115.
31) Li Meng-Hua, Kui Li, Juha Kantanen, Zheng Feng, Bin Fan, Shu-Hong Zhao(通訊作者). 2005. Allelic variations in exon 2 of caprine MHC class II DRB3 gene in Chinese indigenous goats. Small Ruminant Res.2006, 66: 236-243
32) Uthe JJ, Stabel TJ, Zhao SH, Tuggle CK, Bearson SM. Analysis of porcine differential gene expression following challenge with Salmonella enterica serovar Choleraesuis using suppression subtractive hybridization. Veterinary Microbiology, 2006, 114: 60-71.
34) Zhang DX, Li K, Liu B, Zhu ZM, Xu XW, Zhao SH, Yerle M, Fan B. Chromosomal localization, spatio-temporal distribution and polymorphism of the porcine tripartite motif-containing 55 (TRIM55) gene. Cytogenetic and Genome Research, 2006, 114: 93B
35) Fan B, Chen SL, Liu B, Zhao SH, Yu M, Zhu MJ, Xiong TA, Li K. Genetic variations of 13 indigenous Chinese goat breeds based on Cytochrome b gene sequences. Biochemical Genetics, 2006, 44: 89-99
36) Wang HL, Wang H, Zhu ZM, Wu X, Yu M, Zhao SH, Yang SL, Li K. Full-length cDNA, molecular characterization and physical mapping of five genes from a porcine fetal cDNA library. Animal Genetics, 2006, 37: 82-4.
37) Kim JW, Zhao SH, Uthe JJ, Bearson SM, Tuggle CK. Assignment of the scavenger receptor class B, member 2 gene (SCARB2) to porcine chromosome 8q11-->q12 by somatic cell and radiation hybrid panel mapping. Cytogenetic & Genome Research, 2006, 112: 342H.
38) Wang XM, Liu B, Zhao SH, Fan B, Zhu MJ, Yu M, Xiong TA, Li K. Sequence identification, tissue distribution, mapping and polymorphism of the porcine sar1b gene. Animal Biotechnology, 2006, 17: 99-107
39) Chen S, Fan B, Liu B, Yu M, Zhao S, Zhu M, Xiong T, Li K. Genetic variations of 13 indigenous Chinese goat breeds based on cytochrome B gene sequences. Biochem Genet. 2006, 44:89-99.
40) H. L.Wang, Z. M. Zhu, H. Wang, S. L. Yang, S.H. Zhao, K. Li. Molecular characterization and association analysis of porcine CA3. Cytogenetic and Genome Research, 2006, 15: 129-133
41) Mei Yu, Max F. Rothschild, J. Yang, S.H. Zhao, K. Li. Linkage mapping of five genes on SSC12 in a Berkshire × Yorkshire cross. Archive of Animal Breeding, 2006,49: 13-18
42) Kim JW, Zhao SH, Uthe JJ, Bearson SM, Tuggle CK. Physical mapping of eight pig genes whose expression level is acutely affected by Salmonella challenge. Animal Genetics, 2005, 36: 359-62.
43) Lee S-H, Zhao S-H, Recknor J, Nettleton D, Tuggle CK. Gene expression profiling during porcine peri-implantation stage using cDNA macroarray. Molecular Reproduction and Development,2005, 71: 129-39.
44) Wu X, Zhao SH, Yu M, Zhu ZM, Wang H, Wang HL, Li K. Physical mapping of four porcine 20S proteasome core complex genes (PSMA1, PSMA2, PSMA3 and PSMA6). Cytogenetic and Genome Research, 2005, 108: 363I.
45) Li SJ, Zhao SH, Tuggle CK. Somatic cell hybrid and RH mapping of the tachykinin 3 gene to porcine chromosome 5. Animal Genetics, 2005, 36: 90-91.
46) Yu J, Liu B, Fan B, Zhu MJ, Xiong TA, Yu M, Li K, Zhao SH(通訊作者). The porcine FBXO32 gene: map assignment, SNP detection and tissue expression. Animal Genetics, 2005, 36: 451-452.
47) Zhao SH and Tuggle CK. Mapping of the porcine suppressor of cytokine signalling 3 gene to chromosome 12 using somatic cell and radiation hybrid panels. Anim. Genet. 2005 Feb;36(1):88-90.
48) Mengjin Zhu, Bang Liu, Mei Yu, Shuhong Zhao, Bin Fan, Changchun Li, Zhongzhen Peng. Comparative evaluation of loin muscle area estimated by pixel method and empirical formula method in Swine. Livestock Research for Rural Development, 2005, 17: 126.
51) Li MH, Li K, Zhao SH (通訊作者). Diversity of Chinese indigenous goat breeds: a conservation perspective. Asian-Australasian Journal of Animal Sciences. 2004, 17(5): 726-732.
52) Li SJ, Yang SH, Zhao SH, Fan B, Yu M, Wang HS, Li MH, Liu B, Xiong TA and Li K. Genetic diversity analyses of 10 indigenous Chinese pig populations based on 20 microsatellites. Journal of Animal Science, 2004, 82: 368–374.
53) Wu X, Yu M, Liu B, Zhao S.H, Yerle M, Wang Y.F, Fan B, Zhu M, Li K. Mapping of three porcine 20S proteasome genes using IMpRH panel. Cytogenetic & Genome Research,2004, 106:142E.
54) Li CC, Wang ZG, Liu B, Yang SL, Zhu ZM, Fan B, Yu M, Zhao SH and Li K. Evaluation of the genetic relationship among ten Chinese indigenous pig breeds with twenty-six microsatellite markers. Asian-Australasian Journal of Animal Sciences, 2004, 17: 441-444.
55) Zhao SH and Tuggle CK, Linkage mapping and expression analyses of a novel gene, placentally expressed transcript 1(PLET1) in the pig. Animal Genetics, 2004, 35: 72-74.
56) Zhao SH, Erickson A, Tuggle CK. Physical and linkage mapping of the lymphocyte antigen 86 (LY86) gene to porcine chromosome 7. Animaal Genetics,2004, 35: 164.
58) Fan B, Yang SL, Liu B, Yu M, Zhao SH and Li K. Characterization of the genetic diversity on natural populations of Chinese miniature pig breeds. Animal Genetics, 2003, 34: 465 –466.
59) Pan PW, Li K, Tuggle CK, Yu M, Liu B and Zhao SH(通訊作者). Sequencing, tissue distribution and mapping of the porcine homologue of physicacardiomyopathy associated 3 (CMYA3). Animal Genetics, 2003, 34: 473 –474.
60) Yang SL, Wang ZG, Liu B, Zhang GX, Zhao SH, Yu M, Fan B, Li MH, Xiong TA, Li K. Genetic variation and relationships of eighteen Chinese indigenous pig breeds. GeneticSelectionEvolution, 2003, 35: 657–671.
61) Yang J, Wang J, Kijas J, Liu B, Han H, Yu M, Yang H, Zhao S and Li K. Genetic Diversity Present Within the Near-Complete mtDNA Genome of 17 Breeds of Indigenous Chinese Pigs. Journal of Heredity, 2003, 94: 381–385.
62) Wang YF, Yu M, Yerle M, Liu B, Zhao SH, Xiong TA, Fan B and Li K. Mapping of genes encoding four ATPase and three non-ATPase components of the pig 26S proteasome. Animal Genetics, 2003, 34: 393 –395.
63) Mo DL, Liu B, Wang ZG, Zhao SH, Yu M, Fan B, Li MH, Yang SL, Zhang GX, Xiong TA and Li K. Genetic variation and relationship of seventeen Chinese indigenous pig breeds using ten serum protein loci. Asian-Australasian Journal of Animal Sciences, 2003, 16: 939-944.
64) Pan PW, Zhao SH, Yu M, Liu B, Xiong TA and Li K. Identification of differentially expressed genes in the longissimus dorsi muscle tissue between duroc and erhualian pigs by mRNA differential display.Asian-Australasian Journal of Animal Sciences, 2003,16: 1066-1070.
65) S-H. Zhao and C.K. Tuggle,Assignment1 of lymphocyte antigen 64 homolog,radioprotective 105 kDa (LY64) gene to porcine chromosome band 16q14 with somatic cell hybrids and linkage mapping. Cytogenetic & Genome Research, 2003, 101: 92B.
68) B. Liu, G Jin, S Zhao, M Yu, Z Peng, K Li, Preparation and analysis of spermatocyte meiotic pachytene bivalents of pigs for gene mapping, Cell Research, 2002, 12: 401-405.
69) M. Yu, S. Zhao, M. Yerle, B. Liu, T. Xiong and K. Li, Isolation, physical mapping and polymorphism of the porcine ferredoxin reductase (FDXR) gene, Animal Genetics, 2002, 33: 394-395.
70) B. Fan , Z.-G. Wang , Y.-J. Li , X.-L. Zhao, B. Liu , S.-H. Zhao , M. Yu, M.-H. Li , S.-L. Chen, T.-A. Xiong& K. Li*, Genetic variation analysis within and among Chinese indigenous swine populations using microsatellite markers,Animal Genetics , 2002, 33: 422-427.