袁吉鋒，男，博士，廈門大學生命科學學院，閩江學者特聘教授。
基本介紹
- 中文名：袁吉鋒
- 學位/學歷：博士
- 職業：教師
- 專業方向：合成生物學、代謝工程、基因組編輯
- 任職院校：廈門大學生命科學學院
個人經歷,研究方向,學術成果,
個人經歷
西安交通大學學士（2007）；
新加坡南洋理工大學博士（2012）；
新加坡國立大學，研究科學家（2012-2016）；
新加坡科技研究局，高級研究員（2016-2017）；
新加坡國立大學，研究員（2017-2018）；
2018年至今，廈門大學生命科學學院，閩江學者特聘教授。
研究方向
合成生物學、代謝工程、基因組編輯、生物催化與生物轉化、手性不對稱合成、天然產物與藥物合成。
學術成果
代表性論文(Selected Publications, # First author * Corresponding author)
1. Jifeng Yuan*#, Xue Chen, Pranjul Mishra, Chi-Bun Ching. Metabolically engineered budding yeast for enhanced production of isoamyl alcohol.Applied Microbiology and Biotechnology. 2017; 101(1):465-475
2. Jifeng Yuan*#, Chi-Bun Ching. Mitochondrial acetyl-CoA utilization pathway for terpenoid productions. Metabolic Engineering. 2016; 38:303-308
3. Jifeng Yuan*#, Pranjul Mishra, Chi-Bun Ching. Metabolically engineered Saccharomyces cerevisiae for branched-chain ester productions. Journal of Biotechnology. 2017; 239: 90-97
4. Wen Xu, Jifeng Yuan*#,Shuiyun Yang, Chi-Bun Ching, Jiankang Liu. Programming saposin-mediated compensatory metabolic sinks for enhancing ubiquinone productions. ACS Synth Biol. 2016; 5:1404-1411
5. Jifeng Yuan*#, Pranjul Mishra, Chi-Bun Ching. Engineering the leucine biosynthetic pathway for isoamyl alcohol production in budding yeast. Journal of Industrial Microbiology and Biotechnology. 2016; 44(1): 107-117
6. Jifeng Yuan*#, Chi-Bun Ching. Dynamic control of ERG9 expression for improved amorpha-4,11-diene production in Saccharomyces cerevisiae. Microbial cell factories. 2015; 14, 38.
7. Jifeng Yuan*#, Chi-Bun Ching. Combinatorial assembly of large biochemical pathways into yeast chromosomes for improved production of value-added compounds. ACS Synth Biol. 2015;4:23-31.
8. Jifeng Yuan*#, Chi-Bun Ching. Combinatorial engineering of mevalonate pathway for improved amorpha-4,11-diene production in budding yeast. Biotechnol Bioeng. 2014;111(3):608-17.
9. Jifeng Yuan*#, Hongcai Gao, Jianjun Sui, Hongwei Duan, Wei Ning Chen, Chi-Bun Ching. Cytotoxicity evaluation of oxidized single-walled carbon nanotubes and graphene oxide on human hepatoma HepG2 cells: An iTRAQ-coupled 2D LC-MS/MS proteome analysis. Toxicological Sciences. 2012;126(1):149-61.
10. Jifeng Yuan*#, Hongcai Gao, Chi-Bun Ching. Comparative protein profile of human HepG2 cells treated with graphene and single-walled carbon nanotubes: An iTRAQ-coupled 2D LC-MS/MS proteome analysis. Toxicology Letters. 2011:15; 207(3); 213-21.
11. Jifeng Yuan*#, Hongcai Gao, Jianjun Sui, Wei Ning Chen, Chi-Bun Ching. Cytotoxicity of single-walled carbon nanotubes on human hepatoma HepG2 cells: an iTRAQ-coupled 2D LC-MS/MS proteome analysis. Toxicology In Vitro. 2011; 25(8): 1820-7.
