漆淑華

漆淑華,女,博士,現於中國科學院南海海洋研究所任職責任研究員、博士生導師。

基本介紹

  • 中文名:漆淑華
  • 國籍:中國
  • 民族:漢族
  • 職業:博士
  • 性別:女
個人信息,簡歷,獲獎及榮譽,代表論著,科研項目,

個人信息

漆淑華,責任研究員。

簡歷

曾於中國科學院昆明植物研究所植物化學國家重點實驗室獲博士學位香港科技大學博士後,加拿大不列顛哥倫比亞大學做高級訪問學者。目前主要從事海洋天然藥物化學與海洋化學生態學領域的研究,主要研究興趣是從海洋動植物和微生物中尋找有藥用開發前景的活性先導化合物、以及具有重要生態功能的小分子化合物。已從多種藥用植物、南海柳珊瑚、海藻和海洋微生物中分離鑑定了500多個單體化合物,其中包括90多個新化合物,篩選到多個具有強抗腫瘤、或抗病毒藥用活性先導化合物、以及幾十個具有強抗菌、昆蟲拒食性、抗海洋生物污損活性小分子化合物。主持了國家863計畫、國家自然科學基金等10多項國家、省部級科研項目;近年來發表了60多篇研究論文,其中40多篇國際SCI論文,做為第一發明人申請了9項國家發明專利(已獲授權5項),參與編寫兩部專著,參與獲2007年國家科技進步二等獎和2004年海南省科技進步特等獎各一項,已培養多名博士和碩士研究生。

獲獎及榮譽

2007年國家科技進步二等獎,排名第五。 2004年海南省科技進步特等獎,排名第四

代表論著

1. Shu-Hua Qi, Cheng-Hai Gao, Pei-Yuan Qian, Si Zhang. Steroids from the South China Sea gorgonian Subergorgia suberosa. Nat Prod Commun
2. Shu-Hua Qi, Li Miao, Ying Xu, Si Zhang. Steroids and alkaloids from the gorgonian Isis minorbrachyblasta: Structures, cytotoxicity and antilarval activity. Helve. Chim. Acta
3. Shu-Hua Qi, Si Zhang. Steroids and Alkaloids from the South China Sea sponge Axinella sp. Journal of Asian Natural Products Research
4. Shu-Hua Qi, Guo-Chen Su, Yi-Fei Wang, Qiu-Ying Liu, Cheng-Hai Gao. Alkaloids from the South China Sea black coral Antipathes dichotoma. Chem. Pharm. Bull
5. Shu-Hua Qi, Ying Xu, Hai-Rong Xiong, Pei-Yuan Qian, Si Zhang. Antifouling and Antibacterial Compounds from a Marine Fungus Cladosporium sp. F14. World Journal of Microbiology and Biotechnology
6. Shu-Hua Qi, Si Zhang, Bei-Yuan Qian. Antifeedant and antifouling briaranes from the South China Sea gorgonian Junceella juncea. Chemistry of Natural Compounds
7. Shu-Hua Qi, Ying Xu, Hai-Rong Xiong, Pei-Yuan Qian, Si Zhang. Antibacterial and antilarval compounds from marine bacterium Pseudomonas rhizosphaerae. Annals of Microbiology
8. Shu-Hua Qi, Si Zhang, Hui Huang. Four purine alkaloids from the South China Sea gorgonian Subergorgia suberosa. J. Nat. Prod.
9. Shu-Hua Qi, Si Zhang, Bei-Yuan Qian. Antifouling and Antibacterial Compounds of the the South China Sea Gorgonians Subergorgia suberosa and Scripearia gracillis. Nat. Prod. Res
10. Shu-Hua Qi, Si Zhang, Bei-Yuan Qian. Antifeedant, antibacterial and antilarval active secondary metabolites from seagrass Enhalus acoroides. Botan. Mar.
11. Shu-Hua Qi, Si Zhang, Yi-Fei Wang. Complete 1H and 13C NMR assignments of three new polyhydroxylated sterols from the South China Sea gorgonian Subergorgia suberosa. Magn.Res.Chem
12. Shu-Hua Qi, Si Zhang, Bei-Yuan Qian, Zhi-Hui Xiao, Ming-Yi Li. Ten new antifouling briarane diterpenoids from the South China Sea gorgonian Junceella juncea. Tetrahedron
13. Shu-Hua Qi, Si Zhang, Xiang Li, Zhi-Hui Xiao. A New Cytotoxic Sesquiterpene-Alkaloid from the South China Sea gorgonian Subergorgia suberosa. J. Nat.Prod
14. Shu-Hua Qi, Si Zhang, Zhi-Hui Xiao. New Briaranes from the South China Sea Gorgonian Junceella fragilis. Helve. Chim. Acta
15. Shu-Hua Qi, Si Zhang, Zhi-Hui Xiao, Jian-She Huang. Complete 1H and 13C NMR assignments of four new steroidal glycosides from a gorgonian coral Junceella juncea. Magn. Res. Chem
16. Shu-Hua Qi, Si Zhang, Zhi-Hui Xiao, Jian-She Huang. New Briaranes from the South China Sea Gorgonian Junceella juncea. J. Nat. Prod
17. Shu-Hua Qi, Si Zhang, Jian-She Huang, Zhi-Hui Xiao. Study on the Chemical Constituents of the South China Sea gorgonian Junceella juncea. Chem. Pharm. Bull
18. Shu-Hua Qi, Si Zhang, Jian-She Huang, Zhi-Hui Xiao, Jun Wu. Glycerol Derivatives and Sterols from Sargassum parvivesiculosum. Chem. Pharm. Bull.
19. Shu-Hua Qi, Li Chen, Xiao-Dong Luo. Novel Tetranortriterpenoid Derivatives from Munronia henryi. Tetrahedron
20. Shu-Hua Qi, Da-Gang Wu, Li Chen, Yun-Bao Ma, Xiao-Dong Luo. Insect Antifeedants from Munronia henryi: Structure of Munroniamide, J. Agric. Food Chem
21. Shu-Hua Qi, Da-Gang Wu, Yun-Bao Ma, Xiao-Dong Luo, A New Tetranortriterpenoid from Dysoxylum lenticellatum. Z. Naturforsch.
22. Shu-Hua Qi, Da-Gang Wu, Yun-Bao Ma, Xiao-Dong Luo. Chemical Constituents of Ailanthus triphys (leaves). Chinese Journal of Chemistry.
23. Shu-Hua Qi, Da-Gang Wu, Yun-Bao Ma, Xiao-Dong Luo. The Chemical Constituents of Munronia henryi. Journal of Asian Natural Products Research
24. Shu-Hua Qi, Da-Gang Wu, Yun-Bao Ma, Xiao-Dong Luo. A new flavane from Carapa guianensis Aubl. (Meliaceae). Acta Botanica Sinica
25. Shu-Hua Qi, Da-Gang Wu, Si Zhang, Xiao-Dong Luo. Constituents of Carapa guianensis Aubl.( Meliaceae). Pharmacies
26. Cheng-Hai Gao,Xin-Peng Tian, Shu-Hua Qi*, Xiong-Ming Luo, Ping Wang, Si Zhang. Antibacterial and antilarval compounds from marine gorgonian-associated bacterium Bacillus amyloliquefaciens SCSIO 00856. The Journal of Antibiotics
27. Cheng-Hai Gao, Xu-Hua Nong, Shu-Hua Qi*, Xiong-Ming Luo, Si Zhang, Hai-Rong Xiong. A new nine-membered lactone from a marine fungus Cladosporium sp. F14. Chinese Chemical Letters,2010, in press.
28. Jin Yang, Shu-Hua Qi, Si Zhang. Three Polyoxygenated Steroids from the South China Sea Gorgonian Coral Subergorgia reticulate, Chinese Journal of Chemistry
29. Yun-Qi Qiu, Shu-Hua Qi, Si Zhang. New Polyoxygenated Steroids from the South China Sea Gorgonian Echinogorgia aurantiaca, Pharmazie
30. Jin Yang, Shu-Hua Qi, Si Zhang. Bebrycoside, a new steroidal glycoside from the Chinese gorgonian coral Bebryce indica. Pharmazie
31. Yun-Qi Qiu, Shu-Hua Qi, Si Zhang. Thiophene Derivatives From the Ariel Part of Pluchea indica. Heterocycles
32. Guang-Chun Gao, Shu-Hua Qi, Si Zhang. Phenolic compounds and iridoids from the stem bark of Chinese mangrove associate Catunaregam spinosa. Pharmazie
33. Xiong-Ming Luo, Shu-Hua Qi, Hao Yin, Cheng-Hai Gao, Si Zhang. Alkaloids from the Stem Bark of Micromelum falcatum. Chem. Pharm. Bull
34. Xiong-ming Luo, Shu-hua Qi, Hao Yin, Zhi-hui Xiao, Si Zhang. Micromelosides A-D, four new coumarins from the stem bark of Micromelum falcatum. Magnetic resonance in chemistry
35. Jin Yang, Si Zhang, Shu-Hua Qi. Briarane-type diterpenoids from the China gorgonian coral Subergorgia reticulate. Biochemical Systematics and Ecology

科研項目

1.國家863計畫專題課題,負責人,熱帶柳珊瑚和海草中活性先導化合物的發現與結構最佳化,2007-2010年。
2.國家973計畫重要科學前沿領域項目,子課題負責人之一,海洋微生物次生代謝的生理生態效應及其生物合成機制,2009-2014年。
3.國家自然科學基金項目,來源於兩種南海海草的高效低毒海洋防污劑的研究,2010-2012年。
4.國家自然科學基金項目,南海兩種藥用黑角珊瑚中抗腫瘤活性成分及其作用機制的研究,2009-2011年。
5.國家自然科學基金與香港研資局聯合項目,來源於海洋微生物的丁烯酸內酯和吲哚生物鹼兩類抗污損活性化合物的構效關係與作用機制(基因和蛋白水平)的研究,2010-2012年。
6.國家自然科學基金項目,南海側扁軟柳珊瑚中抗癌活性成分的研究,2006-2008年。
7.廣東省自然科學基金,負責人,南海柳珊瑚和海草中低毒抗生物污損物質的發現,2009-2011。
8.廣東省科技計畫項目,負責人,南海柳珊瑚中抗腫瘤活性成分的研究,2008-2010年。
9.廣州市重大科技專項,課題負責人,抗病毒候選藥物黃酮苷HCTHF的研究,2009-2011年。
10.廣東省自然科學基金,負責人,南海海菖蒲中殺蟲活性成分的研究,2006-2007年。
12.中科院重要方向性項目,課題負責人,熱帶海洋微生物活性化合物的研究,2007-2009年。
11.廣東省基金團隊項目,核心團隊成員,南海生物活性先導化合物及其創新藥物研究與開發,2004-2007年。

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