天津大學精密儀器與光電子工程學院學院教授。
從事生物信息檢測技術及儀器領域的研究工作，包括光微流體、聲微流體、電化學感測、超聲微器件、柔性感測器、噴墨列印微製造等。近年來，系統開展了生物微流體與生物感測技術在血糖連續監測中的套用研究。
基本介紹
- 中文名：栗大超
- 外文名：Dachao Li
- 職業：教授
- 畢業院校：天津大學
個人經歷或學術經歷,主持科研項目,代表性論文,獎勵、榮譽和學術兼職,
個人經歷或學術經歷
- 2016年9月至今，天津大學，精密儀器工程系，長聘教授
- 2014年7月至今，天津大學，精密儀器工程系，教授
- 2013年11月至今，天津大學，精密儀器工程系，博士生導師
- 2006年7月至2014年6月，天津大學，精密儀器工程系，副教授
- 2006 年9月至2008年8月，美國CWRU大學，電子工程與計算機科學系，博士後
- 2004 年7月至2006 年6月，北京大學，微電子學研究院，博士後
- 2004 年4月至2006 年6月，天津大學，精密儀器工程系，講師
- 1998 年9月至2004 年3月，天津大學，精密儀器及機械專業，博士
- 1994 年9月至1998年6月，天津大學，精密儀器專業，本科
主持科研項目
1.國家自然科學基金面上項目，基於石墨烯-金納米顆粒修飾的親和型表面等離子共振微葡萄糖感測器。
2.天津市自然科學基金重點項目，金納米顆粒修飾的親和型表面等離子共振微葡萄糖感測器。
3.國家自然科學基金海外及港澳學者合作研究基金項目，用於葡萄糖連續檢測的親和型石墨烯納米感測器。
4.國家自然科學基金外國青年學者研究基金項目，Developments in Additive Microfabrication using Inkjet Printed Gold on Cylindrical Substrates。
5.國家自然科學基金面上項目，細胞間液透皮抽取式血糖連續檢測微晶片的研究。
6.國家863計畫項目子課題，微創血糖連續檢測及胰島素注入系統的研製。
7.天津市科技支撐計畫重點項目，組織液透皮抽取式人體血糖微創監測技術及儀器。
8.教育部促進與美大地區國際合作與高層次人才培養項目，基於納流控技術的連續血糖檢測方法及晶片研究。
9.國家自然科學基金青年教師基金項目，基於人體組織液透皮抽取和分析的微創血糖檢測技術。
10.教育部博士學科點青年教師基金項目，基於低頻超聲和表面等離子共振的微創血糖檢測技術。
11.天津市自然科學基金，非採血式人體血糖濃度的微創檢測技術研究。
代表性論文
代表性期刊論文
[1] Zhihua Pu, Ridong Wang, Jianwei Wu, Haixia Yu, Kexin Xu andDachao Li*, A flexible electrochemical glucose sensor with composite nanostructured surface on the working electrode, Sensors and Actuators B: Chemical, 2016, 213: 801-809
[2]Dachao Li*, Bingyu Lu, Rui Zhu, Haixia Yu, and Kexin Xu, An optofluidic system with volume measurement and surface plasmon resonance sensor for continuous glucose monitoring, Biomicrofluidics, 2016,10 (1): 011913 (10 pages)
[3] Zhihua Pu, Chongwei Zou, Ridong Wang, Xiaochen Lai, Haixia Yu, Kexin Xu, andDachao Li*, A continuous glucose monitoring device by graphene modified electrochemical sensor in microfluidic system, Biomicrofluidics,2016,10(1): 011910 (10 pages)
[4] Jianwei Wu, Ridong Wang, Haixia Yu, Guijun Li, Kexin Xu, Norman C. Tien, Robert C. Roberts,Dachao Li*, Inkjet-Printed Microelectrodes on PDMS as Biosensors for Functionalized Microfluidic Systems, Lab on a Chip, 2015, 15: 690-695
[5]Dachao Li*, Songlin Yu, Changyue Sun, Chongwei Zou, Haixia Yu, Kexin Xu, U-shaped fiber-optic ATR sensor enhanced by silver nanoparticles for continuous glucose monitoring, Biosensors and Bioelectronics, 2015,72: 370–375
[6]Dachao Li*, Jianwei Wu, Peng Wu, Yuan Lin, Yingjuan Sun, Yang Jia, Kexin Xu, Affinity Based Glucose Measurement Using Fiber Optic Surface Plasmon Resonance Sensor with Surface Modification by Borate Polymer, Sensors & Actuators B: Chemical, 2015, 215: 295-304
[7]Dachao Li*, Yanwen Sun, Songlin Yu, Changyue Sun, Haixia Yu, Kexin Xu, A single-loop fiber attenuated total reflection sensor enhanced by silver nanoparticles for continuous glucose monitoring, Sensors and Actuators B: Chemical, 2015, 220: 1033–1042
[8]Dachao Li*, Di Yang, Yang Jia, Yuan Lin, Yingjuan Sun, Haixia Yu, Kexin Xu, Glucose Affinity Measurement by Surface Plasmon Resonance with Borate Polymer Binding, Sensors and Actuators A: Physical, 2015, 222: 58-66
[9]Dachao Li*, Zhihua Pu, Wenshuai Liang, Tongkun Liu, Ridong Wang, Haixia Yu, Kexin Xu, Non-invasive Measurement of Normal Skin Impedance for Determining the Volume of the Transdermally Extracted Interstitial Fluid, Measurement, 2015, 62: 215-221
[10] Songlin Yu,Dachao Li*, Hao Chong, Changyue Sun, Haixia Yu, Kexin Xu, In Vitro Glucose Measurement Using Tunable Mid-Infrared Laser Spectroscopy Combined with Fiber-Optic Sensor, Biomedical Optics Express, 2014, 5(1): 275-286
[11]Dachao Li*, Xiaoli Zhang, Rui Zhu, Peng Wu, Haixia Yu, Kexin Xu, A Method to Detect the Mixed Petrol Interface by Refractive Index Measurement With a Fiber-Optic SPR Sensor, IEEE Sensors Journal, 2014, 14(10): 3701-3707
[12]Dachao Li*, Ridong Wang, Haixia Yu, Guoqing Li , Yue Sun, Wenshuai Liang, Kexin Xu, A Method for Measuring the Volume of Transdermally Extracted Interstitial Fluid by a Three-Electrode Skin Resistance Sensor, Sensors, 2014, 14: 7084-7095
[13] Haixia Yu,Dachao Li*, Yongjie Ji, Xiaoli Zhang, Kexin Xu, An interstitial fluid transdermal extraction chip with vacuum generator and volume sensor for continuous glucose monitoring, Key Engineering Materials, 2013, 562-565: 571-575
[14] Songlin Yu,Dachao Li*, Hao Chong, Changyue Sun, Kexin Xu, Continuous Glucose Determination Using Fiber-Based Tunable Mid-Infrared Laser Spectroscopy, Optics and Lasers in Engineering, 2014, 55: 78-83
[15] Ting Shi,Dachao Li*, Guoqing Li, Yuan Lin, Kexin Xu, Luo Lu, Development of A Fluorescent Method for Simultaneous Measurement of Glucose Concentrations in Interstitial Fluid and Blood, Measurement Science and Technology, 2013, 24(12): 125701
[16] Haixia Yu,Dachao Li*, Robert C. Roberts, Kexin Xu, Norman C. Tien, A Micro PDMS Flow Sensor Based on Time-of-Flight Measurement for Conductive Liquid, Microsystem Technologies, 2013, 19(7): 989-994
[17] Haixia Yu,Dachao Li*, Robert C. Roberts, Kexin Xu, Norman C. Tien, An Interstitial Fluid Transdermal Extraction System for Continuous Glucose Monitoring, Journal of Microelectromechanical Systems, 2012, 21(4): 917-925
[18] Haixia Yu,Dachao Li*, Robert C. Roberts, Kexin Xu, Norman C. Tien, Design, Fabrication and Testing of A Micro-Venturi Tube for Fluid Manipulation in A Microfluidic System, Journal of Micromechanics and Microengineering, 2012, 22(3) : 035010 (9pp)
[19] Haixia Yu,Dachao Li*, Robert C. Roberts, Kexin Xu, Norman C. Tien, A Time-of-Flight Flow Sensor for the Volume Measurement of Trace Amount of Interstitial Fluid, Journal of Micromechanics and Microengineering, 2012, 22(5) : 055009 (7pp)
代表性國際會議論文
[1] B. Lu, X. Lai, P. Zhang, H. Wu, and D. Li*, “Roughened Cylindrical Gold Layer With Curve Graphene Coating For Enhanced Sensitivity of Fiber SPR Sensor”, IEEE Int. Conf. Solid-State Sensors, Actuators and Microsystems (Transducers ’17), June 18-22, 2017, Kaohsiung, Taiwan.
[2] X. Lai, B. Lu, H. Wu, Z. Pu, H. Yu, andD. Li*, “A Novel Method for Generating Monodispersed Droplet Array by Inkjet-Patterned Hydrophilic Symbols for Controlled Reactions”, IEEE Int. Conf. Solid-State Sensors, Actuators and Microsystems (Transducers ’17), June 18-22, 2017, Kaohsiung, Taiwan.
[3] Z. Pu, X. Zhang, H. Wu, H. Yu, andD. Li*, “Cylindrical Electrochemical Sensor Fabricated by Rotated Inkjet Printing on Flexible Substrate for Glucose Monitoring”, IEEE Int. Conf. Solid-State Sensors, Actuators and Microsystems (Transducers ’17), June 18-22, 2017, Kaohsiung, Taiwan.
[4] Bingyu Lu, Yanwen Sun, Xiaochen Lai, Zhihua Pu, Haixia Yu, Kexin Xu andDachao Li*, Side-polished Fiber SPR Sensor with Temperature Self-compensation for Continuous Glucose Monitoring, The 29th IEEE International Conference on Micro Electro Mechanical Systems (MEMS 2016), 24-28 January, 2016, Shanghai, China.
[5] Chongwei Zou, Chengtao Sun, Haixia Yu, Kexin Xu andDachao Li*, Continuous glucose monitoring system based on enzyme colorimetry sensor and microfluidic chip, The 9th International Conference on Advanced Technologies & Treatments for Diabetes(ATTD 2016), February 3-6, 2016, Milan, Italy.
[6]Dachao Li*, Changyue Sun, Haixia Yu, Kexin Xu, Fabrication of Silver Nanoparticles on Cylindrical Surface of U-Shaped Fiber ATR Sensor by Material Reduction, The 28th IEEE International Conference on Micro Electro Mechanical Systems (MEMS 2015), January 18-22, 2015, Estoril, Portugal.
[7]Dachao Li*, Ridong Wang, Zhihua Pu, Haixia Yu, Kexin Xu, A Gold Nanoparticles-based Electrochemical Sensor in Microfluidic for Continuous Glucose Monitoring, The 8th International Conference on Advanced Technologies & Treatments for Diabetes (ATTD 2015), February 18-21, 2015, Paris, France.
[8]Dachao Li*, Jianwei Wu, Peng Wu, Yuan Lin, Yingjuan Sun, Rui Zhu, Jia Yang, Kexin Xu, Glucose Measurement Using Surface Plasmon Resonance Sensor with Affinity based Surface Modification by Borate Polymer, The 18th International Conference on Solid-State Sensors, Actuators and Microsystems (Transducers 2015), June 21-25, 2015, Alaska, USA.
[9]Dachao Li*, Haixia Yu, Songlin Yu, Peng Wu, Ting Shi, Glucose Continuous Monitoring in Interstitial Fluid by Microfluidic, The 5th International Conference on Optofluidics (Optofluidics 2015), 26-29 July, 2015, Taipei, Taiwan.
[10] Zhihua Pu, Ridong Wang, Haixia Yu, Kexin Xu,Dachao Li*, A Wearable Continuous Glucose Monitoring System with Electrochemical Sensor Modified by Graphene, The 19th International Conference on Miniaturized Systems for Chemistry and Life Science (MicroTAS 2015), October 25-29, 2015, Gyeongju, Korea.
[11] Changyue Sun, Yuzhen Cao, Yanwen Sun, Songlin Yu, Haixia Yu*,Dachao Li, Flattened Fiber ATR Sensor Enhanced by Silver Nanoparticles for Continuous Glucose Monitoring, The 19th International Conference on Miniaturized Systems for Chemistry and Life Science (MicroTAS 2015), October 25-29, 2015, Gyeongju, Korea.
[12] Chongwei Zou, Chengtao Sun, Haixia Yu, Kexin Xu,Dachao Li*, An Optofluidic System based on Enzyme Colorimetry for Continuous Glucose Monitoring, The 19th International Conference on Miniaturized Systems for Chemistry and Life Science (MicroTAS 2015), October 25-29, 2015, Gyeongju, Korea.
[13] Zhihua Pu, Ridong Wang, Haixia Yu, Kexin Xu,Dachao Li*, A Flexible Electrochemical Sensor Modified by Graphene and AuNPs for Continuous Glucose Monitoring, The 14th IEEE SENSORS Conference (IEEE Sensors 2015), November 1-4, 2015, Busan, Korea.
[14] Yanwen Sun, Changyue Sun, Songlin Yu, Haixia Yu*,Dachao Li, Single-Loop Fiber ATR Sensor Enhanced by Silver Nanoparticles for Continuous Glucose Monitoring, The 14th IEEE SENSORS Conference (IEEE Sensors 2015), November 1-4, 2015, Busan, Korea.
[15]Dachao Li*, Ridong Wang, Zhihua Pu, Haixia Yu, Kexin Xu, A Gold Nanoparticles-based Electrochemical Sensor in Microfluidic for Continuous Glucose Monitoring, Advances in Microfluidics and Nanofluidics 2014 Meeting (AMN2014), May 19 to 24, 2014,Taipei,Taiwan.
[16] Jianwei Wu, Robert C. Roberts, Norman C. Tien,Dachao Li*, Inkjet Printed Silver Patterning on PDMS to Fabricate Microelectrodes for Microfluidic Sensing, The 13th IEEE Conference on Sensors (IEEE Sensors 2014), November 2-5, 2014, Valencia, Spain.
[17] Jianwei Wu, Robert C. Roberts, Norman C. Tien,Dachao Li*, Inkjet Printed Microelectrode on PDMS for Manufacturing a Microfluidic Biosensing System, The 4th International Conference on Optofluidics (Optofluidics 2014), August 28-30, 2014, Guangzhou, China.
[18]Dachao Li*and Kexin Xu, Minimally Invasive Glucose Measurement based on Interstitial Fluid Extracted Transdermally, Biomedical Engineering Suzhou International Symposium (BMESIS 2014), April 8-10, 2014, Suzhou, China
[19] Songlin Yu,Dachao Li*, Changyue Sun, Haixia Yu, Kexin Xu , Silver-nanoparticle-enhanced bent fiber-optic ATR sensor combined with tunable mid-infrared laser for glucose measurement, 7th Asia-Pacific Conference on Transducers and Micro/Nano Technologies (APCOT 2014), June 29 – July 2, 2014, Daegu, Korea.
[20] Jianwei Wu, Robert C. Roberts, Norman C. Tien,Dachao Li*, Inkjet Printed Multimetal Microelectrodes on PDMS for Functionalized Microfluidic Systems, The 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2014), October 26-30, 2014, San Antonio, USA.
[21]Dachao Li*, Haixia Yu, Jianwei Wu, Di Yang, Yuan Lin, Qian Wang, Kexin Xu, An Optical Lab-on-a-Chip System Based on SPR Sensor for Continuous Glucose Monitoring, The 17th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2013), October 27-31, 2013, Freiburg, Germany.
[22]Dachao Li*, Haixia Yu, Xian Huang, Bing Song, Yuan Jia, Yongjie Ji, Kexin Xu, Qiao Lin, A Microfluidic System with Volume Sensor and Dielectric Glucose Sensor for Continuous Glucose Monitoring, The 17th International Conference on Solid-State Sensors, Actuators and Microsystems (Transducers 2013), June 16-20, 2013, Barcelona, Spain.
[23]Dachao Li*, Rui Zhu, Peng Wu, Jianwei Wu, Kexin Xu, Measurement of Glucose Concentration by Fiber-Optic Surface Plasmon Resonance Sensor, SPIE Photonics West 2013, February 2-7, 2013, San Francisco, USA.
[24]Dachao Li*, Yang Jia, Peng Wu, Di Yang, Bo Wang, Yuan Lin, Kexin Xu, Glucose Measurement by Surface Plasmon Resonance with Borate Polymer Binding, SPIE Photonics West 2013, February 2-7, 2013, San Francisco, USA.
[25]Dachao Li*, Ridong Wang, Hao Chong, Liu Yu, Kexin Xu, Glucose Measurement in Interstitial Fluid by Microdialysis for the Calibration of Minimally Invasive Blood Glucose Monitoring, SPIE Photonics West 2013, February 2-7, 2013, San Francisco, USA.
[26] Songlin Yu,Dachao Li*, Kexin Xu, Tunable Mid-Infrared Laser Spectroscopy for Glucose Measurement, Conference on Laser Surgery and Medicine 2012 (CLSM 2012), April 25-27, 2012, Yokohama, Japan.
[27]Dachao Li*, Peng Wu, Jia Yang, Rui Zhu, Kexin Xu, An Implantable Fiber-optic Surface Plasmon Resonance Glucose Sensor based on TFBG, Conference on laser surgery and medicine 2012 (CLSM 2012), April 25-27, 2012, Yokohama, Japan.
[28]Dachao Li*, Peng Wu, Rui Zhu, Yang Jia, Haixia Yu, Kexin Xu, Implantable Fiber-optic SPR Sensor Modified with LPFG and PAA-ran-PAAPBA for Continuous Glucose Monitoring, The 11th IEEE Sensors Conference (IEEE Sensors 2012), October 28-31, 2012, Taipei, Taiwan.
[29]Dachao Li*, Rui Zhu, Peng Wu, Yang Jia, Kexin Xu, An Implantable Fiber-Optic Surface Plasmon Resonance Glucose Sensor Based on LPFG, SPIE Photonics West 2012, January 22-26, 2012, San Francisco, USA.
[30] Ting Shi,Dachao Li*, Yongjie Ji, Guoqing Li , Kexin Xu, Modeling of Relationship between Glucose Concentration in Blood and Glucose Concentration in Interstitial Fluid, SPIE Photonics West 2012, January 22-26, 2012, San Francisco, USA.
[31] Haixia Yu,Dachao Li*, Yongjie Ji, Xiaoli Zhang, Kexin Xu, An Interstitial Fluid Transdermal Extraction Chip with Vacuum Generator and Volume Sensor for Continuous Glucose Monitoring, The 14th Annual Conference of the Chinese Society of Micro/Nano Technology ( CSMNT 2012), November 4-7, 2012, Hangzhou, China.
獎勵、榮譽和學術兼職
- 2013年入選教育部“新世紀優秀人才支持計畫；
- 2014年獲得“教育部技術發明一等獎”；
- 2015年入選天津大學“北洋青年學者支持計畫”；
- 中國高等教育學會測控技術專業委員會委員；
- 天津市攜帶型醫療電子設備企業重點實驗室學術委員會委員。
