惠永正，男，1939年12月生，江蘇蘇州人，1962年畢業於北京大學化學系。後就職於中科院上海有機化學研究所、國家科委等。
基本介紹
- 中文名：惠永正
- 出生地：江蘇蘇州
- 出生日期：1939年12月
- 畢業院校：北京大學
- 研究領域：糖化學
人物經歷,主要工作成就,發表論文,
人物經歷
1959.9－1962.7 北京大學
惠永正圖片
惠永正圖片1962.9－ 中科院上海有機化學研究所
1982.2－1983.1 美國 University of North Carolina at Chapel Hill
1983.2－1983 12 美國 Rutgers University
1991.1－ 國家科委
主要工作成就
惠永正早期從事物理有機化學研究，系統地研究了糖澱粉及其衍生物作為宿主體系的宿主－客體化學， 隨後研究領域擴展到計算機化學和微泡體化學。近年來主要從事微泡體化學和糖化學研究，包括長鏈、多氟代長鏈化物的微泡體的性質和生物合功能模擬: 複雜寡糖的化學合成及糖綴合物中糖鏈與生物功能之間關係的研究。早年曾從事計算機化學和微環境效應研究，曾獲全國科學大會獎(1978)，中科院科學進步一等獎(1986)，國家自然科學三等獎(1988)，和中科院發明一等獎(1997)。至今共發表論文71篇。共培養碩士研究生7，博士研究生6名，合作培養博士生8名。
發表論文
1. Inter-Domain Movenment of Spin Lables in the Vesicle Monolayers of Hybride bolaamphiphiles.
B.Y.Z.Hui, Supramolecular Chem., 1995, 5, 193-195
2. Direct Facile Tetrahydrofuranylation of Alcohols in p-TsCl/NaH/THF System.
B.Y.Z.Hui, Synth. Commun., 1995,25, 2037
3. A New Highly Regioselective Reaction of Unprotected Sugars for Chemical Synthesis of -Acyl-D-glucopyranosides.
J.Xia, Y.Z.Hui, Synth. Commun., 1995, 25, 2235-2251
4. An Efficient and Stereospecific Synthesis of 1-Stearoyl-2-[(z,z,z)-9,12,15-Linolenoyl]-sn-Glycerophosphocholine and its Bioactivity.
J.Xia, Y.Z.Hui, Bioorg. Med. Chem. Lett., 1995,5(17),1919-1922
5. A New Strategy for the Stereoselective Synthesis of 2,3-Dideoxy-3-Fluoro-D-Ribofuranose Derivatives.
Z.W.Guo, B.G.Huang, W.J.Xia, Y.Z.Hui, S..Lang, Chin. J. Chem., 1995,13,363
6. Chemical Synthesis of a Commonly Occurring Saponin Trisaccharide: a -L-Rhaminosyl-(1-4)-b nosyl-(1-6)-D-Glucopyranose.
M.Z.Liu, Z.W.Guo, Y.Z.Hui, Carbonhydr. Lett., 1995, 1, 387-392
7. An Efficient and Stereospecific Synthesis of 1-Palmitoyl-2-[(z,z,z)-9,12,15-Linolenoyl]-sn-Glycerophophocholine.
J.Xia, Y.Z.Hui, Chin. Chem. Lett., 1995, 6(10), 863-866
8. A General Method for the Synthese of Ether Phospholipids with a -Linolenic Acid and Their Properties.
J.Xia, Y.Z.Hui, Bioorg. Med. Chem. Lett., 1995, 5(23), 2815-2820
9. A New Highly Regioselective Reaction of Unprotected Sugars for Chemical Synthesis of Methyl-6-D-Acyl-D-Glycopyranoside by Means of Chlorophosphoric Acid Diethyl Ester as Condensing Reagent.
J.Xia, Y.Z.Hui, Synth. Commun, 1996, 26(2), 269-278
10. A Convenient Method for Highly Selective Deprotection of Benzylidene Acetals from Sugars
J.Xia, Y.Hui, Synth. Commum., 1996, 26(5), 881-886
11. The TMSOTf-Promoted "One Pot" -Glycosidations of Peracetylated Chitobiose.
B.Q. Ouyang, Y.Z.Hui, J. Carbohydr. Chem., 1996, 15(3), 297-302
12. Chemical Synthesis of (3-SO3Na) GlcNAc b 1-3Fuc b 1-OMe: The Oligocaccharide Involved in the Cell Aggregation of the Sponge Microcina Prolifera.
Z.W.Guo, S.J.Deng, Y.Z.Hui, J. Carbohydr. Chem., 1996, 15(8), 965-974
13. A New Strategy for the Stereoselective Syntheses of C-Glycosyl Compounds of b -Pentapyranoses.
Z.W.Guo, Y.Z.Hui, Synth. Commun., 1996, 26(11), 2067-2073
14. Supramolecular Assemblies from Single-Chain Hydrocarbon Fluorocarbon Hybrid Bolaamphiphiles.
B. Y.Z.Hui, Chin. J. Chem., 1996, 14(2), 171-179
15. Structural Study on a Bioactive Fructan from the Root of Achyranthes Bidentata Blume.
B. G.Y.Tian, Y.Z.Hui, Chin. J. Chem., 1996, 13(6), 539-544
16. A One-Step Procedure for Facile, Selective Synthesis of Protected D-Glucopyranosides with Free 2-C Hydroxyl Group Starting from Peracetylated b-D-Glucopyranose.
; M.Z.Liu, H.N.Fan, Z.W.Guo, Y.Z.Hui,Chin. J. Chem., 1996, 14(2), 190-192
17. One-Step Glycosylation and Selective Deprotection of Peracetylated Monosaccharides for Facile Syntheses of Allyl Glycosides with a Free C-2 Hydroxyl Group.
M.Z.Liu, H.N.Fan, Z.W.Guo, Y.Z.Hui, Carbonhydr. Res., 1996, 290, 233-237
18. A New Reaction for One-pot, Selective Mono-O-Glycosylations of 9,10- Dihydroxyphenanthrene Under Mild Conditions.
Z.W.Guo, Y.Z.Hui, Chin.Chem.Lett., 1996, 7(5), 423-424
19. Isolation and Structure Elucidation of a Polysaccharide with Radiation-Protective Activity from Spinulina Platensis.
Z.W.Guo, Y.Z.Hui, Chin.J. Chem., 1996, 14(3), 279-285
20. A One-Step Procedure for Facile Preparation of D-Glucopyranosides with a Free 2-OH from Peracetylated b -D-Glucopyranose.
M.Z.Liu, H.N.Fan, Z.W.Guo, Y.Z.Hui,J. Carbohydr. Chem., 1996, 15(9), 1139-1145
21. The Stereospecific Synthesis of Mixed-acid Phospholipids with Polyunsaturated Fatty Acid from D-mannitol.
J. Xia, Y. Z. Hui, Tetrahedron: Asymmetry, 1997, 3, 451-485
22. Recent Progress of Saponin Research.
M.Z.Liu, Z.W.Guo, Y.Z.Hui, Natural Product Research and Development, 1997, 9(2), 81-85
23. A Facial Regioselective 1,6-O-Diacetylation Method of Methyl glycopyranosides and Their Dimethyl Phosphonates.
G.T.Zhang, Z.W.Guo, Y.Z.Hui, Synth. Commun., 1997, 27(11), 1907-1918
24. First Total Synthesis of Tricolorin A.
S., Q.Q.Ouyang, Z.W.Guo, , Y.Z.Hui, Angew. Chem. Int. Ed. Engl., 1997, 36, 2344-2346.
25. A Synthesis of Tricolorin A.
S., Q.Q.Ouyang, Z.W.Guo, Y.Z.Hui, J.Org.Chem., 1997, 62, 8400-8405.
26. Synthesis and Antitumor Activities of Diosgenyl Glycosides.
M.Z.Liu, , Z.W.Guo, Y.Z.Hui, Carbohydr. Lett., 1997, 2,423-428.
27. Conformational Analysis of Two Diosgenyl Saponins.
M.Z.Liu, , M.B.Chen, C.L.Feng, Y.Z,Hui, Chin. Chem. Lett., 1997, 8, 785-788.
28. A New Method for the Cleavage of Carbohydrate Benzylidene Acetyl by Ceric (IV) Ammonium Nitrate in CH3CN-H2O (10:1).
S., Q.Q.Ouyang, Z.W.Guo, , Y.Z.Hui, Chin. Chem. Lett., 1997, 8, 841.
29. Efficient One-Step Methyl Esterification of Carboxylic Acid and Deacetylation by BF3OEt2-MeOH.
S., Q.Q.Ouyang, Z.W.Guo, , Y.Z.Hui, Chin. Chem. Lett., 1997, 8, 843.
30. What is the Sugar Chains¡¯ Function in Saponin.
M.Z.Liu, Z.W.Guo, Y.Z.Hui, Youji Huaxue, 1997, 17, 307.
31. Recent Progress on Resin Glycoside Research.
S., Q.Q.Ouyang, Z.W.Guo, Y.Z.Hui, Youji Huaxue, 1997, 17(4), 1
