丙螺氯銨，英文名稱為1-chloro-3-[12-(3-chloro-2-hydroxypropyl)-3,12-diaza-6,9-diazoniadispiro[5.2.59.26]hexadecan-3-yl]propan-2-ol,dichloride，分子式為C18H36Cl2N4O2++。
基本介紹
- 中文名：丙螺氯銨
- 化學式：C18H36Cl2N4O2++
- 分子量：411.41000
- CAS登錄號：23476-83-7
英文別名,化合物簡介,
英文別名
Prospidium chloride; Cloruro de prospidio [INN-Spanish]; Prospidii chloridum [INN-Latin]; PROSPIDIUM; 3,12-Bis(3-chloro-2-hydroxypropyl)-3,12-diaza-6,9-diazoniadispiro[5.2.5.2]hexadecane dichloride;Prospidine; Chlorure de prospidium [INN-French]; Prospidin;
化合物簡介
Prospidium chloride is a spiro compound.Definition of Prospidin: A Russian Drug, a dispiropiperazine derivative with potential cytostatic, anti-inflammatory and immune-suppressive properties. Although the exact mechanism of action of prospidin is not known, this agent was shown to interact with DNA, disrupting cell cycle at G2 phase, inhibiting phagocytic activity of monocytes and macrophages. This compound had a registration for Squamous Cell Carcinoma of the Head&Neck, reports exist about its activity in HIV-Related Kaposi Sarcoma. Prospidin has good anti-lupus activity due to its immunosuppressant effects and was also used in refractory Rheumatoid Arthritis as an anti-rheumatic drug. Usually, it has no Hematologic Toxicity. (NCI04) Prospidin is from the group; DNA Adduct Forming Agent Immunosuppressant; Other Names for Prospidin; Prospidin; 3,12-Diaza-6,9-diazoniadispiro（5.2.5）.
