peptides是一個英語單詞,詞性為名詞,譯為“多肽類;縮氨酸”等。多肽是由胺基酸通過醯胺鍵連線形成的化合物,分子量一般小於10kDa或少於40個胺基酸,廣泛參與生物體內系統調節。根據生理功能可分為多肽激素、免疫活性肽、抗菌多肽和抗病毒多肽等類別。多肽組指生物樣本中全部內源性多肽組份,多肽組學則系統性研究其成分、功能及變化規律。
多肽藥物因其活性顯著、毒性低等優勢成為研發熱點,口服司美格魯肽通過SNAC保護劑實現胃部吸收並於2019年獲FDA批准。深度學習技術(如RFpeptides)可精準設計環肽結構以提升靶點結合能力。全球多肽新藥臨床階段達463個,中國占75個;FDA於2023年發布多肽藥物臨床藥理學指南。《Peptides》期刊專注於多肽研究,2015年刊文探討蛻皮抑制激素對甲殼動物基因表達的調控作用。
基本介紹
- 外文名:peptides
- 詞性:名詞
- 類型:英語單詞
單詞釋義
- n. 多肽類;[生化] 縮氨酸
短語搭配
雙語例句
- Some proteins are produced with transit peptides. 一些蛋白質的生產過境肽。
- Copper peptides. Copper peptides improve the healing of wound. 含銅的肽類物質增強傷口癒合。
- The initial uptake of the native protein peptides is in the mouth. 在最初的天然蛋白肽的吸收是在嘴裡。
- DNA, Proteins, And Peptides Could Help Construct New Nanoscale electronics. 蛋白質和肽能幫助我們構建嶄新的納米尺度電子學。
- Structure of antimicrobial peptides is closely related to their bioactivity. 抗菌肽的結構組成與其生物活性密切相關。
- This was a far more powerful rate than using the drug without added peptides. 比起使用沒加多肽的藥物是非常強勁的速度了。
- Polyclonal antibody preparation against the peptides of NDRG family proteins. 抗人ndrg家族寡肽的多克隆抗體製備。
- In the future, antimicrobial peptides will take up the battle against pathogens. 將來,抗微生物肽將占據對抗病原體的市場。
- The disease is caused by the accumulation in the brain of molecules known as peptides. 這個疾病是由一種肽狀分子在大腦中的累積沉澱而引起的。
- This is, however, unlikely to occur for peptides with a high affinity for the cell surface. 然而,這種作用對於和細胞表面有高親和力的多肽是不太可能發生的。
- The enzyme armoury is sufficient to degrade most proteins to small peptides and amino acids. 這一酶庫足以將大多數蛋白質降解成短肽和胺基酸。
- Emory University scientists have discovered that simple peptides can organize into bi-layer membranes. 埃默里大學的科學家們發現,簡單的肽可以組織成雙向層膜。
- Here these designer lipid-like peptides may play a key role in improving effective drug delivery systems. 而類脂多肽將在提高藥物輸送系統效率方面起到重要作用。
- Objective To investigate the effects of several vasoactive peptides on the development of restenosis. 目的研究血管活性肽在血管再狹窄形成中的作用。
- So if we are giving the patients these peptides every day, it needs a lot of grant to do the research. 所以如果我們每天給患者進行注射,那將需要相當大的經費來進行這一研究。
- For the study, the researchers extracted proteins known as peptides from white cells in alligator blood. 在這項研究中,研究人員從鱷魚血的白細胞中提取出被稱為肽的蛋白質。
- Some claim that nutrients like copper peptides, biotin, folic acid, and others may help support healthy hair. 有人聲稱,如銅肽,生物素,葉酸的營養素等可能有助於健康的頭髮。
- The genes which determined the structures of certain proteins (peptides) was called as structural genes. 結構基因指決定某種多肽鏈(蛋白質)或酶分子結構的基因。
- “Forget about all the technical issues of making mirror ribosomes, mirror peptides, and mirror DNA, ” he says. “要產生鏡像核糖體、鏡像多肽和鏡像DNA,拋開技術層面不談,”斯佐斯塔克說。
- This method provides an excellent way for high expression of antimicrobial peptides when fused with EDDIE. 以EDDIE為融合蛋白是在大腸桿菌中高效表達抗菌肽的一種好方法。
- The group has previously shown that alpha-helical peptides can be imitated by something called a alpha-hairpin turn. 小組之前證明α螺旋多肽能被α髮夾旋轉限制。
- "Peptide molecular medicine is a very hot area, and this concept of stapled peptides is a new area of great promise," he said. 肽類藥物是個非常熱門的領域。釘肽的概念是一個有巨大潛力的新領域。
- DXY: I found from your publications that the research have been done in humans, so is there any of these peptides in clinical trial? 丁香園:從您的出版物來看,您的研究是以人為研究對象的,那么這些肽是否有套用在臨床試驗上?
- They detailed their findings in the report on the impact of integrating short surfactant-like designer peptides in lipidic nanostructures. 小組主要研究了將類似表面活性劑的短鏈多肽結合到脂類納米結構之後對後者的影響。
- However, the purification of antimicrobial peptides have not yet been finished, it will be carried on in our laboratory in the future. 由於時間所限,拮抗蛋白的純化、測序工作尚未完成,在以後的時間裡,本實驗室還將繼續這方面的研究。
- When the researchers tested the peptides out on bacteria, viruses, and fungi, some of them turned out to be very powerful germ killers. 當研究人員拿細菌、病毒和真菌來測試這些抗菌肽時,他們發現其中有些抗菌肽是威力極強的殺菌劑。
- These two kinds of multi - peptides 'regulating effect on blood vessel tension may have major influences on essential hypertension (EH). 這兩種多肽對血管張力的調節作用可能對原發性高血壓(EH)的發病有著重要影響。

