《Cancer Biology》是由美國學者Raymond W. Ruddon編著、英國牛津大學出版社於2007年3月出版的學術專著，屬於基礎醫學與分子生物學領域的專業文獻。該書基於1995年第三版框架更新，延續了作者對癌症生物學機制的系統性研究。
全書以細胞與分子生物學視角為核心，解析正常細胞惡性轉化的病理機制，包括癌細胞侵襲宿主組織、轉移擴散的動態過程及腫瘤微環境調控作用。通過整合實驗數據與理論模型，梳理癌症研究領域的關鍵科學問題，同時結合腫瘤免疫學、基因靶向治療等臨床套用，呈現基礎研究與臨床實踐的關聯性。書中包含544頁學術論述，附有示意圖及截至成書時的前沿參考文獻。
基本介紹
- 外文名：Cancer Biology
- 作者：Ruddon, Raymond W.
- 出版社：Oxford Univ Pr
- ISBN：9780195175448
內容簡介
A thorough yet concise account of cancer biology, this book emphasises the cellular and molecular mechanisms involved in the transformation of normal into malignant cells, the invasiveness of cancer cells into host tissues, and the metastatic spread of cancer cells in the host organism. It also defines the fundamental pathophysiological changes that occur in tumour tissue and in the host animal or patient. The approach throughout the book is to discuss the historical development of a field, citing the key experimental advances to the present day, and to evaluate the current evidence that best supports or rules out concepts of the molecular and cellular mechanisms regulating cancer cell behaviour. For all the areas of fundamental cancer research, an effort has been made to relate basic research findings to the clinical disease states. The book is well illustrated with schematic diagrams and actual research data to demonstrate points made in the text, and there is an extensive, up-to-date bibliography.
