黃佳穎(廣州醫科大學生命科學學院教授)

黃佳穎(廣州醫科大學生命科學學院教授)

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黃佳穎,女,博士研究生,現任廣州醫科大學生命科學學院教授,博士生導師,南山學者。

基本介紹

人物經歷,工作經歷,研究方向,期刊論文,

人物經歷

2011-2015 華南師範大學生命科學學院,生命科學勷勤創新班,理學學士
2014-2015 深圳華大基因創新班,聯合培養學生
2015-2021 北京大學生命科學學院,生物技術,理學博士
2019-2020 美國羅格斯新澤西州立大學,國家公派聯培博士研究生

工作經歷

2021-2023 中國科學院遺傳與發育生物學研究所,博士後
2023- 廣州醫科大學生命科學學院,教授

研究方向

圍繞多種基因編輯新工具進行大數據挖掘,並進行理性突變和改造,以套用需求為導向,最佳化編輯工具,實現對疾病模型的創製以及致病位點的精準編輯。

期刊論文

1. Huang, J.#, Lin, Q.#, Fei, H.#, He, Z.#, Xu, H., Li, Y., Qu, K., Han, P., Gao, Q., Li, B., Liu, G., Zhang, L., Hu, J., Zhang, R., Zuo, E., Luo, Y., Ran, Y., Qiu, J.L., Zhao, K.T.*, and Gao, C.* (2023). Discovery of deaminase functions by structure-based protein clustering. Cell 186, 3182-3195. (2023年度中國科學十大進展; Best of Cell 2023; Highlighted by Trends in Plant Science; Highlighted by Science Bulletin; Selected by F1000Prime)
2. Huang, J.#, Dong, J.*, & Qu, L. J.* (2021). From birth to function: Male gametophyte development in flowering plants. Curr. Opin. Plant Biol. 63, 102118.
3. Valliyodan, B.#, Qiu, D.#, Patil, G.#, Zeng, P.#, Huang, J.#, Dai, L.#, Chen, C., Li, Y., Joshi, T., Song, L., Vuong, T. D., Musket, T. A., Xu, D., Shannon, J. G., Cheng, S., Liu, X.*, & Nguyen, H. T.* (2016). Landscape of genomic diversity and trait discovery in soybean. Sci. Rep. 6, 23598.
4. Shi, Y.#, Huang, J., Sun, T., Wang, X., Zhu, C., Ai, Y., and Gu, H.* (2017). The precise regulation of different COR genes by individual CBF transcription factors in Arabidopsis thaliana. J. Integr. Plant Biol. 59, 118-133.
5. Sun, Y.#, Huang, J., Zhong, S., Gu, H., He, S.*, and Qu, L.-J.* (2018). Novel DYW-type pentatricopeptide repeat (PPR) protein BLX controls mitochondrial RNA editing and splicing essential for early seed development of Arabidopsis. J. Genet. Genomics 45, 155-168.
6. Iorizzo, M.#, Ellison, S., Senalik, D., Zeng, P., Satapoomin, P., Huang, J., Bowman, M., Iovene, M., Sanseverino, W., Cavagnaro, P., Yildiz, M., Macko-Podgórni, A., Moranska, E., Grzebelus, E., Grzebelus, D., Ashrafi, H., Zheng, Z., Cheng, S., Spooner, D., Van Deynze, A., and Simon, P.* (2016). A high-quality carrot genome assembly provides new insights into carotenoid accumulation and asterid genome evolution. Nat. Genet. 48, 657-666.
7. Zhang, J.#, Huang, Q.#, Zhong, S.#, Bleckmann, A., Huang, J., Guo, X., Lin, Q., Gu, H., Dong, J., Dresselhaus, T., and Qu, L.-J.* (2017). Sperm cells are passive cargo of the pollen tube in plant fertilization. Nat. Plants 3, 17079.
8. Zhong, S.#, Liu, M.#, Wang, Z.#, Huang, Q., Hou, S., Xu, Y. C., Ge, Z., Song, Z., Huang, J., Qiu, X., Shi, Y., Xiao, J., Liu, P., Guo, Y. L., Dong, J., Dresselhaus, T., Gu, H., and Qu, L.-J.* (2019). Cysteine-rich peptides promote interspecific genetic isolation in Arabidopsis. Science 364, eaau9564.
9. Yuan, R.#, Lan, J., Fang, Y., Yu, H., Zhang, J., Huang, J., and Qin, G.* (2018). The Arabidopsis USL1 controls multiple aspects of development by affecting late endosome morphology. New Phytol. 219, 1388-1405.
10. Cheng, S.#, Gutmann, B.#, Zhong, X.#, Ye, Y., Fisher, M.F., Bai, F., Castleden, I., Song, Y., Song, B., Huang, J., Liu, X., Xu, X., Lim, B. L., Bond, C.S.*, Yiu, S.M.*, Small, I.* (2016). Redefining the structural motifs that determine RNA binding and RNA editing by pentatricopeptide repeat proteins in land plants. Plant J. 85, 532-547.

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