鄧正玉

鄧正玉,中國科學技術大學生物醫學工程特任研究員,博士生導師。

人物經歷,研究方向,學術論文,

人物經歷

工作經歷:
2024/07-,中國科大蘇州高等研究院,特任研究員
2021/3-2024/06,加拿大西安大略大學 (University of Western Ontario),博士後,導師:Elizabeth R. Gillies
2017/6-2019/09,湖南大學,博士後, 導師:譚蔚泓 院士
學習經歷:
2011/09-2017/03,中國科學技術大學高分子科學與工程系,博士,導師:劉世勇 教授
2007/09-2011/06,西北工業大學套用化學系,學士

研究方向

智慧型生物材料,精密高分子,生物正交化學

學術論文

1.Deng, Z.; Liang, X.; Gillies, E. R.* "Click to Self-immolation: A “Click” Functionalization Strategy towards Triggerable Self-Immolative Homopolymers and Block Copolymers", Angew. Chem. Int. Ed. 2024, 63, e202317063 (Hot Paper).
2.Tan, J.; Deng, Z.; Song, C.; Xu J.; Zhang, Y.; Yu, Y.; Hu, J.*; Liu, S.* "Coordinating External and Built-In Triggers for Tunable Degradation of Polymeric Nanoparticles via Cycle Amplification", J. Am. Chem. Soc. 2021, 143, 13738 (Equal first author).
3.Yang, Q.; Deng, Z.; Wang, D.; He, J.; Zhang, D.; Tan, Y.; Peng, T.; Wang, X. Q.*; Tan, W.* "Conjugating Aptamer and Mitomycin C with Reductant-Responsive Linker Leading to Synergistically Enhanced Anticancer Effect", J. Am. Chem. Soc. 2020, 142, 2532 (Equal first author).
4.Deng, Z.; Yuan, S.; Xu, X. R.; Liang, H.; Liu, S.* "Reduction-Triggered Transformation of Disulfide-Containing Micelles at Chemically Tunable Rates", Angew. Chem. Int. Ed. 2018, 57, 8896.
5.Deng, Z.; Qian, Y.; Yu, Y.; Liu, G.; Hu, J.; Zhang, G.; Liu, S.* "Engineering Intracellular Delivery Nanocarriers and Nanoreactors from Oxidation-Responsive Polymersomes via Synchronized Bilayer Cross-Linking and Permeabilizing Inside Live Cells", J. Am. Chem. Soc. 2016, 138, 10452 (ESI Highly Cited Papers).
6.Deng, Z.; Gillies, E. R.* "Emerging Trends in the Chemistry of End-to-End Depolymerization", JACS Au 2023, 3, 2436.
7.Shi, Q.; Deng, Z.; Hou, M.; Hu X.*; Liu S.* "Engineering precise sequence-defined polymers for advanced functions", Prog. Polym. Sci. 2023, 141, 101677 (Equal first author).

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