研究方向
1.微生物組研究(細菌組、真菌組、病毒組):包括自身免疫疾病、肺部疾病、消化道疾病等多種疾病,方法學探索及構建(如病毒組學、真菌組)及其在臨床疾病中的套用;
2.培養組學研究:腸道、口腔、生殖道及腫瘤相關部位的細菌及真菌的大規模分離培養,菌庫構建,及菌株相關致病功能機制探索;
3.益生菌及中草藥:益生菌的分離、益生功能挖掘及其與中草藥互作研究
工作經歷
2016-2022 大連醫科大學 微生態與病原生物學教研室 講師
2022-2024 大連醫科大學 微生態與病原生物學教研室 副教授
2024-2025 大連醫科大學 微生態與病原生物學教研室 教授
2025-至今 南方醫科大學第五附屬醫院 微生態醫學中心 教授
近三年代表論文
1.QiulongYan et al. “A genomic compendium of cultivated human gut fungi characterizesthe gut mycobiome and its relevance to common diseases.” Cell vol.187,12 (2024): 2969-2989.e24.
2.LianshaHuang et al. “A multi-kingdom collection of 33,804 reference genomes for thehuman vaginal microbiome.” Nature microbiologyvol. 9,8(2024): 2185-2200.
3.QiulongYan et al. “The Chinese gut virus catalogue reveals gut virome diversity anddisease-related viral signatures.” Genome medicine vol.17,1 30. 26 Mar. 2025.
4.XianggeTian et al. “Gut virome-wide association analysis identifies cross-populationviral signatures for inflammatory bowel disease.” Microbiome vol.12,1 130. 18 Jul. 2024.
5.WenSun et al. “A population-scale analysis of 36 gut microbiome studies revealsuniversal species signatures for common diseases.” NPJ biofilms andmicrobiomes vol. 10,1 96. 1 Oct. 2024.
6.Liu, Jianjun et al. “Integrative metagenomic and metabolomic analyses reveal the potential of gut microbiota to exacerbate acute pancreatitis.” NPJ biofilms and microbiomes vol. 10,1 29. 21 Mar. 2024.
7.Chen, Fang et al. “Meta-analysis of fecal viromes demonstrates high diagnostic potential of the gut viral signatures for colorectal cancer and adenoma risk assessment.” Journal of advanced research vol. 49 (2023): 103-114.
8.Wang, Guangyang et al. “Optimization and evaluation of viral metagenomic amplification and sequencing procedures toward a genome-level resolution of the human fecal DNA virome.” Journal of advanced research vol. 48 (2023): 75-86.
9.Chen, Chang-Ming et al. “Distinct characteristics of the gut virome in patients with osteoarthritis and gouty arthritis.” Journal of translational medicine vol. 22,1 564. 13 Jun. 2024.
10.Xing, Yida et al. “Multikingdom characterization of gut microbiota in patients with rheumatoid arthritis and rheumatoid arthritis-associated interstitial lung disease.” Journal of medical virology vol. 96,7 (2024): e29781.