郭瑋煒

郭瑋煒，博士，南開大學化學學院研究員、博士生導師。

基本介紹

• 中文名：郭瑋煒
• 國籍：中國
• 民族：漢
• 出生地：山西長治
• 畢業院校：中科院長春應化所電分析國家重點實驗室
• 學位/學歷：博士
• 職業：教師
• 專業方向：智慧型生化分析
• 職務：研究員
• 任職院校：南開大學

研究領域

智慧型生化分析

功能DNA水凝膠

螢光納米探針

DNA納米技術

個人經歷

1999.09-2003.07 吉林大學化學學院 理學學士

2004.09-2010.07 中科院長春應化所電分析國家重點實驗室 理學博士 （導師：汪爾康院士）

2010.08-2011.10 中科院長春應化所電分析國家重點實驗室 研究助理

2011.11-2015.11 以色列耶路撒冷希伯來大學 化學所 博士後 （合作導師：Itamar Willner 教授）

2015.11至今南開大學化學學院 研究員 博士生導師

榮譽獎項

2015年 南開大學百名青年學術帶頭人培養計畫

2019年 第四批國家“萬人計畫”青年拔尖人才

學術成果

郭瑋煒研究員致力於發展智慧型的生化分析方法和感測裝置，集中研究具備多功能可編碼的DNA感測材料包括DNA水凝膠與納米結構等感測材料及結合納米簇、量子點和功能二維結構等的複合功能感測材料的設計、調控及相關基礎科學問題，建立和發展針對不同類型生化分析目標的分離檢測新原理與新方法，進而發展智慧型的生化分析試紙與晶片、穿戴式生化感測器和植入式診療一體化系統，目前已經取得了一系列創新研究成果，發表SCI論文40餘篇，總引用次數超過2400次，H-index為 27。其中，以第一(共同第一)或通訊作者發表SCI論文20餘篇，包括2篇《J. Am. Chem. Soc.》，2篇《Angew. Chem. Int. Ed.》，3篇《Adv. Mater.》，2篇《Adv. Funct. Mater.》，2篇《Small》，1篇《Chem. Sci.》等高影響力SCI收錄學術雜誌論文，最高單篇他引超過380次，多篇學術論文被評為ESI高被引論文(Highly Cited Papers)。此外，擔任中文核心期刊《分析試驗室》編委（第五屆），及擔任Angew. Chem. Int. Ed., Adv. Mater., Chem. Sci., ACS Nano, ACA等Wiley/ACS/RSC/Elsevier出版社旗下十多個業界公認的國際頂級或高水平學術期刊的獨立通訊評審人和仲裁評審。目前，已先後主持國家自然科學基金青年與面上項目、天津市自然科學基金重點項目以及南開大學百青項目等多項。

Selected Publications:

(1) Fengyun Li, Danya Lyu, Shuo Liu, Weiwei Guo*, DNA Hydrogels and Microgels for Biosensing and Biomedical Applications, Adv. Mater. 2019,

(2) Chunyan Wang, Fengyun Li, Yanhui Bi, Weiwei Guo*, Reversible Modulation of Two-Dimensional Photonic Crystals with a Responsive Shape-Memory DNA Hydrogel Film, Adv. Mater. Interfaces 2019,

(3) Danya Lyu, Jing Li, Xiaowen Wang, Weiwei Guo*, and Erkang Wang*, Cationic Polyelectrolyte Modified Fluorescent DNA-Silver Nanoclusters for Rapid Bioimaging with Enhanced Emission and Higher Stability, Anal. Chem. 2019,

(4) Yanhui Bi, Cuiyan Han, Weiwei Guo*, Smart DNA Hydrogels for Biosensing Applications, Sci Sin Chim, 2019,

(5) Fengyun Li, Qi Gao, Mingjie Yang, Weiwei Guo*, Regulation of Catalytic DNA Activities with Thermosensitive Gold Nanoparticle Surfaces, Langmuir, 2018,

(6) Shuo Liu, Weiwei Guo*, Anti-Biofouling and Healable Materials: Preparation, Mechanisms, and Biomedical Applications, Adv. Funct. Mater. 2018,

(7) Jingrun Ran, Weiwei Guo*, Hailong Wang, Bicheng Zhu, Jiaguo Yu, Shi-Zhang Qiao*, Metal-Free 2D/2D Phosphorene/g-C3N4 Van der Waals Heterojunction for Highly Enhanced Visible-Light Photocatalytic H2 Production, Adv. Mater. 2018,

(8) Shanshan Chen, Danya Lyu, Tao Ling, Weiwei Guo*, Reversible Modulation of CsPbBr3 Perovskite Nanocrystal/gold Nanoparticle Heterostructures, Chem. Commun. 2018,

(9) Jingtao Wang(#), Pingping Chen(#), Benbing Shi, Weiwei Guo*, Mietek Jaroniec, Shi-Zhang Qiao*, Regularly Channeled Lamellar Membrane for Unparalleled Water and Organics Permeation, Angew. Chem. Int. Ed. 2018,

(10) Fengyun Li, Chunyan Wang, and Weiwei Guo*, Multifunctional Poly-N-Isopropylacrylamide/DNAzyme Microgels as Highly Efficient and Recyclable Catalysts for Biosensing, Adv. Funct. Mater. 2018,

(11) Danya Lyu, Shanshan Chen, Weiwei Guo*, Liposome Crosslinked Polyacrylamide/DNA Hydrogel: a Smart Controlled-Release System for Small Molecular Payloads, Small 2018,

(12) Weiwei Guo(#), Chun-Hua Lu(#), Ron Orbach, Fuan Wang, Xiu-Juan Qi, Alessandro Cecconello, Dror Seliktar, Itamar, Willner*, pH-Stimulated DNA Hydrogels Exhibiting Shape-Memory Properties, Adv. Mater., 2015,

(13) Chun-hua Lu(#), Weiwei Guo (#), Yuwei Hu, Xiu-Juan Qi, Itamar Willner*, Multi-Triggered Shape-Memory Acrylamide-DNA Hydrogels, J. Am. Chem. Soc., 2015,

(14) Weiwei Guo(#), Chun-Hua Lu(#), Xiu-Juan Qi, Ron Orbach, Michael Fadeev, Huang-Hao Yang, Itamar Willner*, Switchable Bifunctional Stimuli-Triggered Poly-N-Isopropylacrylamide/DNA Hydrogels, Angew. Chem. In. Ed. 2014,

(15) Weiwei Guo, Jipei Yuan, Qingzhe Dong, Erkang Wang*, Highly sequence-dependent formation of fluorescent silver nanoclusters in hybridized DNA duplexes for single nucleotide mutation identification, J. Am. Chem. Soc., 2010,

(16) Chun-hua Lu(#), Weiwei Guo (#), Xiu-Juan Qi, Avner Neubauer, Yossi Paltiel, Itamar, Willner*, Hemin-G-quadruplex-crosslinked poly-N-isopropylacrylamide hydrogel: a catalytic matrix for the deposition of conductive polyaniline, Chem. Sci. 2015,

(17) Weiwei Guo(#), Ron Orbach(#), Iris Mironi-Harpaz, Dror Seliktar, Itamar Willner*, Fluorescent DNA hydrogels composed of nucleic Acid-stabilized silver nanoclusters, Small, 2013,

(18) Weiwei Guo(#), Xiu-Juan Qi(#), Ron Orbach, Chun-hua Lu, Lina Freage, Iris Mironi-Harpaz, Dror Seliktar, Huang-Hao Yang, Itamar Willner, Chem. Commun., 2014,

(19) Ron Orbach(#), Weiwei Guo(#), Fuan Wang, Oleg Lioubashevski, Itamar Willner*, Self-Assembly of Luminescent Ag Nanocluster-Functionalized Nanowires, Langmuir, 2013,

(20) Weiwei Guo, Jipei Yuan, Erkang Wang*, Oligonucleotide-stabilized Ag nanoclusters as novel fluorescence probes for the highly selective and sensitive determination of Hg2+ ion, Chem. Commun., 2009,