蔡翠芳(瀋陽藥科大學藥學院副教授)

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蔡翠芳,女,山東省慶雲縣人,是瀋陽藥科大學藥學院副教授。

基本介紹

人物經歷,主講課程,主要貢獻,獲獎記錄,

人物經歷

1995年畢業於華東理工大學,獲化學製藥專業學士學位。
2001年畢業於瀋陽藥科大學,獲藥劑學碩士學位。
2005年獲得德意志學術交流中心(DAAD)獎學金,在德國馬爾堡大學(Philipps Universität of Marburg, Germany)從事博士課題的研究,在2007年9月畢業獲德國藥學博士學位。

主講課程

講授生命科學與技術基地班《藥劑學》(雙語授課)及《藥劑學實驗》(雙語授課);講授藥學(英語班)《藥劑學》課程(雙語授課)及專業英語(藥劑學部分)。
目前指導本科專題生多名,碩士研究生5人,協助指導博士研究生1人。

主要貢獻

博士課題的研究內容為可降解聚合物微球及納米粒的蛋白輸送研究。近年來參加了多項課題的研究,主持瀋陽藥科大學回國人員科學研究啟動項目,參與德國國家自然科學基金課題及企業研究課題的研究工作,多次參加國內外學術會議並做大會報告。主要從事非口服緩控釋製劑的研究,特別是可降解聚合物微球及納米粒的蛋白輸送研究。
代表論著
近幾年,在國內、外發表研究論文10餘篇,參編教材、專著5本。
代表性著作
1. 國家執業藥師資格考試藥劑學過關全攻略,遼寧科學技術出版社,2008(副主編)。
2. 製劑工藝放大,化學工業出版社,2009(參編)。
3. 專業英語(藥劑學部分),瀋陽藥科大學教材建設委員會,2009(主編)。
4. 藥劑學實驗(英語版),瀋陽藥科大學教材建設委員會,2009(參編)。
5. 英漢藥劑學辭彙, 瀋陽藥科大學教材建設委員會,2009(參編)。
代表性論文:
1. C. Cai, Bakowsky U, Rytting E, Schaper AK, Kissel T. Charged nanoparticles as protein delivery systems: A feasibility study using lysozyme as model protein. Eur J Pharm Biopharm 2008, 69(1):31-42.
2. C. Cai, S. Mao, O. Germershaus, A. Schaper, E. Rytting, D. Chen, and T. Kissel. Influence of morphology and drug distribution on the release process of FITC-dextran loaded microspheres prepared with different types of PLGA. J. Microencapsulation 2009, 26(4): 334-345.
3. C. Chen, D. Han, C. Cai,, X. Tang An overview of liposome lyophilization and its future potential. Journal of Controlled Release 2010, 142(3): 299-311.
4. S. Mao, J. Xu, C. Cai, O. Germershaus, A. Schaper, and T. Kissel. Effect of WOW process parameters on morphology and burst release of FITC-dextran loaded PLGA microspheres. Int. J. Pharm. 2007, 334 (1-2):137-48.
5. X. Wang, X. Xie, C. Cai, E. Rytting, T. Steele,† and T. Kissel Biodegradable Branched Polyesters Poly(vinyl sulfonate-covinyl alcohol)-graft Poly(D,L-lactic-coglycolic acid) as a Negatively Charged Polyelectrolyte Platform for Drug Delivery: Synthesis and Characterization Macromolecules, 41 (8), 2791–2799, 2008
6. C. Cai, Hellwig M., Bakowsky U., Rytting E., and Kissel T. A facile method to prepare protein loaded nanoparticles. Controlled Release Society German Chapter Annual Meeting in Freiburg, March 2007, Germany. 2007, 3.22-3.23
7. C. Cai, Sitterberg J., Rytting E., Schaper A., and Kissel T. A facile method to prepare protein loaded nanocarrier with a layer-by-layer nanostructure. The 3th Materialforschungstag Mittelhessen, 6 July 2007, Germany
8. C. Cai, Germershaus O., Mao S., Schaper A., and Kissel T. Influence of porosity and PLGA polymer nature on the release behavior of FITC-dextran loaded PLGA microspheres. Controlled Release Society German Chapter Annual Meeting in Freiburg, March 2007, Germany. 3.22-3.23
9. S. Mao, J. Xu, C. Cai, O. Germershaus, A. Schaper, T.Kissel. Influence of process parameters on the internal morphology of FITC-dextran loaded PLGA microspheres. CRS Meeting in Jena, February 2006, Germany.
10. 蔡翠芳 鄒梅娟 唐星李積軍. 醋酸地塞米松聚乳酸-羥基乙酸共聚物緩釋微球含量和體外釋放度測定. 中國藥劑學雜誌 2008 6 (3): 72-76。
11. 蔡翠芳,唐 星,李積軍 川芎中阿魏酸的提取純化工藝,瀋陽藥科大學學報 2008 25 (01): 70-72。

1. C. Cai, Bakowsky U, Rytting E, Schaper AK, Kissel T. Charged nanoparticles as protein delivery systems: A feasibility study using lysozyme as model protein. Eur J Pharm Biopharm 2008, 69(1):31-42.
2. C. Cai, S. Mao, O. Germershaus, A. Schaper, E. Rytting, D. Chen, and T. Kissel. Influence of morphology and drug distribution on the release process of FITC-dextran loaded microspheres prepared with different types of PLGA. J. Microencapsulation 2009, 26(4): 334-345.
3. C.Chen, D.Han, C.Cai,, XingTang An overview of liposome lyophilization and its future potential Journal of Controlled Release xxx(2009)xxx–xxx(article in press)
4. S. Mao, J. Xu, C. Cai, O. Germershaus, A. Schaper, and T. Kissel. Effect of WOW process parameters on morphology and burst release of FITC-dextran loaded PLGA microspheres. Int. J. Pharm. 2007, 334 (1-2):137-48.
5. X. Wang, X. Xie, C. Cai, E. Rytting, T. Steele,† and T. Kissel Biodegradable Branched Polyesters Poly(vinyl sulfonate-covinyl alcohol)-graft Poly(D,L-lactic-coglycolic acid) as a Negatively Charged Polyelectrolyte Platform for Drug Delivery: Synthesis and Characterization Macromolecules, 41 (8), 2791–2799, 2008.
6. Zhao M, Su M, Lin X, Luo Y, He H, Cai C, Tang X. Evaluation of docetaxel-loaded intravenous lipid emulsion: pharmacokinetics, tissue distribution, antitumor activity, safety and toxicity. Pharm Res. 2010,27(8):1687-702.
7. Yang R, Gao RC, Cai CF, Xu H, Li F, He HB, Tang X. Preparation of gel-core-solid lipid nanoparticle: a novel way to improve the encapsulation of protein and peptide. Chem Pharm Bull. 2010, 58(9):1195-202.
8. C. Cai, Hellwig M., Bakowsky U., Rytting E., and Kissel T. A facile method to prepare protein loaded nanoparticles. Controlled Release Society German Chapter Annual Meeting in Freiburg, March 2007, Germany. 2007, 3.22-3.23。
9. C. Cai, Sitterberg J., Rytting E., Schaper A., and Kissel T. A facile method to prepare protein loaded nanocarrier with a layer-by-layer nanostructure. The 3th Materialforschungstag Mittelhessen, 6 July 2007, Germany 。
10. C. Cai, Germershaus O., Mao S., Schaper A., and Kissel T. Influence of porosity and PLGA polymer nature on the release behavior of FITC-dextran loaded PLGA microspheres. Controlled Release Society German Chapter Annual Meeting in Freiburg, March 2007, Germany. 3.22-3.23。
11. S. Mao, J. Xu, C. Cai, O. Germershaus, A. Schaper, T.Kissel. Influence of process parameters on the internal morphology of FITC-dextran loaded PLGA microspheres. CRS Meeting in Jena, February 2006, Germany. 。
12. 蔡翠芳 鄒梅娟 唐星 李積軍. 醋酸地塞米松聚乳酸-羥基乙酸共聚物緩釋微球含量和體外釋放度測定. 中國藥劑學雜誌 2008 6 (3): 72-76。
13. 蔡翠芳,唐 星,李積軍 川芎中阿魏酸的提取純化工藝 瀋陽藥科大學學報 2008 25 (01): 70-72。

獲獎記錄

所參與的項目微粒型系列口服緩釋製劑研製獲2009年瀋陽市科技進步二等獎。

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