胃飢餓素(ghrelin)是胃內產生的一種肽，它能夠調節食慾、進食和身體構成。
基本介紹
- 中文名：胃飢餓素
- 外文名：ghrelin
- 解釋：一種肽
- 性質：能夠調節食慾、進食和身體構成
- 產生場所：胃
概述,生理作用,
概述
Ghrelin is a hormone produced mainly by P/D1 cells lining the fundus of the human stomach and epsilon cells of the pancreas that stimulates hunger. Ghrelin levels increase before meals and decrease after meals. It is considered the counterpart of the hormone leptin, produced by adipose tissue, which induces satiation when present at higher levels. In some bariatric procedures, the level of ghrelin is reduced in patients, thus causing satiation before it would normally occur.
Ghrelin是一種激素，主要由人胃底部的P / D1細胞和胰腺的ε細胞產生，刺激飢餓。飯前Ghrelin水平升高，飯後降低。它被認為是由脂肪組織產生的激素瘦素的對應物，當以較高水平存在時誘導飽食。在一些減肥手術中，患者的胃飢餓素水平降低，因此在正常情況發生之前引起飽腹感。
生理作用
Ghrelin plays a significant role in neurotrophy, particularly in the hippocampus, and is essential for cognitive adaptation to changing environments and the process of learning. Recently, ghrelin has been shown to activate the endothelial isoform of nitric oxide synthase in a pathway that depends on various kinases including Akt.
胃飢餓素在神經營養中具有重要的作用，尤其是在海馬體中，而這（胃飢餓素）對認識（人）對環境改變的適應和學習能力的進程具有重要的作用。最近，胃飢餓素被認為能通過包括Akt在內的多種激酶的一條通路激活一氧化氮合成酶的內皮同種型。
