同濟大學附屬東方醫院主治醫師，同濟大學碩士生及本科生導師
基本介紹
- 中文名：梁淑靜
- 國籍：中國
- 民族：漢族
- 臨床職稱：主治醫師
- 執業地點：上海市東方醫院
人物經歷,研究方向,科研概況,科研成果,
人物經歷
上海市東方醫院 主治醫師
研究方向
乳腺癌等免疫治療及納米材料在其治療中的套用
科研概況
目前已參與多項生物納米及腫瘤免疫相關領域相關研究工作，掌握乳腺癌及其它腫瘤免疫治療及納米材料套用領域的最新研究進展，熟悉免疫細胞的分離培養，掌握小鼠乳腺原位荷瘤鼠模型的建立，及分子生物學實驗等技術。本課題申請者承擔國家自然科學基金、浦東新區衛計委衛生科研青年項目及優秀青年人才培養行動計畫等多項科研課題，已在納米生物醫學相關領域SCI及核心期刊雜誌發表文獻數篇。協助培養多名碩士生及博士生。具備臨床及科研工作的能力及基礎。
科研成果
1. Shujing Liang, Chao Li, Chunlei Zhang, etc.CD44v6 Monoclonal Antibody-Conjugated Gold Nanostars for Targeted Photoacoustic Imaging and Plasmonic Photothermal Therapy of Gastric Cancer Stem-like Cells [J]. Theranostic, 2015, 5(9): 970-984.(IF:8.854)
2. Yonglin Lu, Yain Ma, Chan Feng, Donglei Zhu, Jie Liu, Lv Chen, Shujing Liang, Chunyan Dong. Co-delivery of Cyclopamine and Doxorubicin Mediated by Bovine Serum Albumin Nanoparticles Reverses Doxorubicin Resistance in Breast Cancer by Down-regulating P-glycoprotein Expression [J]. J Cancer, 2019,10(10):2357-2368. (IF:3.182)
3. Chao Li, Shujing Liang, Chunlei Zhang, Yanlei Liu, Meng Yang, Jingpu Zhang, Xiao Zhi, Fei Pan, Daxiang Cui. Allogenic dendritic cell and tumor cell fused vaccine for targeted imaging and enhanced immunotherapeutic efficacy of gastric cancer [J]. Biomaterial, 2015, 54, 177-187.(IF: 8.557 )
4. Chao Li, Ji Yang, Can Wang, Shujing Liang, Fei Pan, Chunlei Zhang, Feng Chen, Hualin Fu, Kan Wang and Daxiang Cui. BRCAA1 antibody-and Her2 antibody-conjugated amphiphilic polymer engineered CdSe/ZnS quantum dots for targeted imaging of gastric cancer[J]. Nanoscale Res Lett, 2014, 9, 1-13. (IF:2.779)
5. Zhang C, Li C, Liu Y, Jingpu Zhang, Chenchen Bao, Shujing Liang, Qing Wang, Yao Yang, Hualin Fu, Kan Wang, and Daxiang Cui. Gold Nanoclusters‐Based Nanoprobes for Simultaneous Fluorescence Imaging and Targeted Photodynamic Therapy with Superior Penetration and Retention Behavior in Tumors[J]. Advanced Functional Materials, 2015, 25, 1314–1325 (IF:11.805)
6. Liang Xu, Xiaobo Wu, Chun Hu, Zhiying Zhang, Le Zhang, Shujing Liang, Yingchun Xu, Fengchun Zhang. A meta-analysis of combination therapy versus single-agent therapy in anthracycline- and taxane-pretreated metastatic breast cancer: results from nine randomized Phase III trials. Onco Targets Ther. 2016, Jul 4;9:4061-74(IF:2.272).
7. Liang Xu, Le Zhang, Chun Hu, Shujing Liang, Xiaochun Fei, Ningning Yan, Yanyun Zhang, Fengchun Zhang. WNT pathway inhibitor pyrvinium pamoate inhibits the self-renewal and metastasis of breast cancer stem cells. Int J Oncol. 2016 Mar;48(3):1175-86(IF: 2.371).
8. Chun Hu, Liang Xu, Shujing Liang, Zhiying Zhang, Yanyun Zhang, Fengchun Zhang. Lentivirus-mediated shRNA targeting Nanog inhibits cell proliferation and attenuates cancer stem cell activities in breast cancer. J Drug Target. 2016;24(5):422-32(IF:2.821).
9. 梁淑靜，徐麗敏等.疣狀表皮發育不良的共聚焦雷射掃描顯微鏡下表現[J]. 中國皮膚性病學雜誌，2011,25(3):231-233.2
9. 梁淑靜，徐麗敏等. 扁平苔蘚的共聚焦雷射掃描顯微鏡特徵表現[J].臨床皮膚科雜誌，2011,40（3）：139-141.
