張慶柱，男，漢族，1956年生，山東濟寧市人，中國醫學科學院•中國協和醫科大學神經藥理學博士研究生畢業，赴日本新潟藥學和套用生命科學大學（Niigata University of Pharmacy and Applied Life Sciences）做研究工作一年。
基本介紹
- 中文名：張慶柱
- 國籍：中國
- 民族：漢族
- 出生地：山東濟寧市
- 出生日期：1956年
- 職業：教師
- 主要成就：藥理學教授，博士生導師
個人履歷,成就及榮譽,
個人履歷
成就及榮譽
發表學術論文百餘篇，10餘篇英文原著被SCI收載或引用。獲山東省科學技術進步獎、省高校優秀科研成果獎勵8項。
主編的著作和教材有《神經藥理學研究技術與方法》（人民衛生出版社，2005年3月），《基礎藥理學》（高等教育出版社，2006年6月），《書寫世界現代醫學史的巨人們-歷屆諾貝爾生理學或醫學獎獲得者的傳奇業績和人生》（中國協和醫科大學出版社，2006年6月），《分子藥理學》（高等教育出版社，2007年5月），《神經藥理學》（人民衛生出版社，2008年2月）。另外，主譯著作1部，副主編專著1部，參編著作1部，參編教材或教學參考書8本。
主要從事細胞內Ca2+調控與神經系統疾病的關係探討，以及ULMWH抗腦缺血、抗AD作用及其機制的系列研究。
近年來發表的論文和出版的著作主要有：
1. Zhi-guo ZHANG, Qing-zhu ZHANG（張慶柱）, Yan-na CHENG, Sheng-li JI, Guan-hua DU. Antagonistic effects of Ultra-Low-Molecular-Weight Heparin against cerebral ischemia/ reperfusion injury in rats. Pharmacological Research（Pharmacol Res），2007；56（4）：350-355.
2. Dakshnamurthy Selvakumar, Qing-Zhu Zhang（張慶柱），Masabiko Miyamota, Yasuhiro Furuichi, Tadazumi Komiyama. Identification and Characterization of a Neutralizing Monoclonal Antibody for the Epitope on HM-1Killer Toxin. J Biochem 2006; 139(10): 399-406.
3. Yong Cheng, Zheng Feng, Qing-Zhu Zhang（張慶柱）, Jun-tian Zhang. Beneficial Effects of Melatonin in Experimental Models of Alzheimer's Disease. Acta Pharmacol Sin 2006; 27 (2): 129-139.
4. Tadazumi Komiyama, Zhang Qingzhu（張慶柱）, Masahiko Miyamoto, Dakshnamurthy Selvakumar, and Yasuhiro Furuichi. Monoclonal Antibodies and Sandwich ELISA for Quantitation of HM-1 Killer Toxin. Biol Pharm Bull 2004; 27(5): 691-693.
5. Yao Jing-Chun, Zhang Qingzhu（張慶柱）. Inhibitory effects of melatonin on the elevation of CD45 expression induced by hypoxia in BV-2 microglia. Chin Pharmacol Toxicol 2004; 13(4): 259.
6. SUN Hua, ZHANG Qing-Zhu et al. Effects of diacetyl guan fu base A on pacemaker cells in sinoatrial node of rabbits. Acta Pharmacol Sin 2002;23(7): 627-630.
7. Wang lizan，Zhang Qingzhu et al. Anti-endotoxic shock effects of cyproheptadine in rats. Chin Med J 2002; 115(3):443-445.
8. Wang lizan，Zhang Qingzhu et al. Verapamil，cyproheptadine and anisodamine antagonized [Ca2+]i elevation induced by TNFαin a single endothelial cell. Acta Pharmacol Sin 2001;22(10): 918-922.
9. Zhang Qingzhu（張慶柱）, Zhang Juntian. Effects of melatonin on the spatial and temporal changes of [Ca2+]i in single living cell of cortical neyrons by laser scanning confocal microscopy. Chin Med J 2000; 113(6):558-562.
10. Zhang Qingzhu（張慶柱）, Zhang Juntian. Antagonistic effects of melatonin on glutamate release and neurotoxicity in cerebral cortex. Acta Pharmacol Sin 1999; 20(9): 829-834
11．張均田，張慶柱主編。《神經藥理學研究技術與方法》。第一版，北京：人民衛生出版社，2005年3月。
12．張慶柱，張均田主編。《書寫世界現代醫學史的巨人們-歷屆諾貝爾生理學或醫學獎獲得者的傳奇業績和人生》。第一版，北京：中國協和醫科大學出版社，2006年6月。
13．張慶柱主編。《基礎藥理學》。第一版，北京：高等教育出版社，2006年6月。
14．張慶柱主編。《分子藥理學》。第一版，北京：高等教育出版社。2007年5月。
15．張均田，張慶柱，張永祥主編。《神經藥理學》。第一版，北京：人民衛生出版社，2008年2月。
Professor of Pharmacology, Director of Department of Clinical Pharmacy
Faculty of Pharmaceutical Sciences, Shandong University
Institute of Pharmacology of New drugs
Faculty of Pharmaceutial Sciences, Western Campus of Shandong University
No. 7 Building, No. 44 Wenhua Xi Road
Jinan 250012, Shandong Province, P. R. China.
PROFILE
Qingzhu Zhang is the Male, the Han Nationality, born in Jinning city of Shandong province on Sept.24, 1956. B.S., graduated from major in medicine.of Qingdao Medical College in 1983. In 1999, he obtained his Ph.D. of Chinese Academy of Medical Sciences & Peking Union Medical College (CAMS & PUMC). Now, he is Prof. in Pharmacology, the tutor of Ph.D. student, and the director of Department of Clinical Pharmacy, Faculty of Pharmaceutical Sciences, Shandong University. He also is the member in Neuropharmacological Committee of the Chinese Pharmacological Society, and the member of standing council of Shandong Pharmacological Society. His research direction is Neuropharmacology, including the effects and mechanisms of melatonin, antioxidants and calcium antagonists on brain disorders or the aged diseases, especially in the relations between antagonists of inositol trisphosphate (IP3) receptor and Ca2+-modulated intracellular Ca2+ releases, and the treatment of Alzheimer’s disease. He holds the second, and third awards of Science and Technology Progressive Prizes (Government and Educational Committee of Shandong Province). 10 academic books were published, two of them in chief-in-editor. The more than 80 of academic articles (70 papers of the first author) had been published in Acta Pharmacol Sin, Chin Med J, Acta Pharm, Chin Pharmacol Toxicol etc., respectively. 10 papers of them were collected and cited in SCI.
DEGREE
Ph.D., Chinese Academy of Medical Sciences & Peking Union Medical College (CAMS & PUMC)
PRINCIPAL PUBLICATIONS
1. Zhi-guo ZHANG, Qing-zhu ZHANG（張慶柱）, Yan-na CHENG, Sheng-li JI, Guan-hua DU. Antagonistic effects of Ultra-Low-Molecular-Weight Heparin against cerebral ischemia/ reperfusion injury in rats. Pharmacological Research（Pharmacol Res），2007；56（4）：350-355.
2. Dakshnamurthy Selvakumar, Qing-Zhu Zhang（張慶柱），Masabiko Miyamota, Yasuhiro Furuichi, Tadazumi Komiyama. Identification and Characterization of a Neutralizing Monoclonal Antibody for the Epitope on HM-1Killer Toxin. J Biochem 2006; 139(10): 399-406.
3. Yong Cheng, Zheng Feng, Qing-Zhu Zhang（張慶柱）, Jun-tian Zhang. Beneficial Effects of Melatonin in Experimental Models of Alzheimer's Disease. Acta Pharmacol Sin 2006; 27 (2): 129-139.
4. Tadazumi Komiyama, Zhang Qingzhu（張慶柱）, Masahiko Miyamoto, Dakshnamurthy Selvakumar, and Yasuhiro Furuichi. Monoclonal Antibodies and Sandwich ELISA for Quantitation of HM-1 Killer Toxin. Biol Pharm Bull 2004; 27(5): 691-693.
5. Yao Jing-Chun, Zhang Qingzhu（張慶柱）. Inhibitory effects of melatonin on the elevation of CD45 expression induced by hypoxia in BV-2 microglia. Chin Pharmacol Toxicol 2004; 13(4): 259.
6. SUN Hua, ZHANG Qing-Zhu et al. Effects of diacetyl guan fu base A on pacemaker cells in sinoatrial node of rabbits. Acta Pharmacol Sin 2002;23(7): 627-630.
7. Wang lizan，Zhang Qingzhu et al. Anti-endotoxic shock effects of cyproheptadine in rats. Chin Med J 2002; 115(3):443-445.
8. Wang lizan，Zhang Qingzhu et al. Verapamil，cyproheptadine and anisodamine antagonized [Ca2+]i elevation induced by TNFαin a single endothelial cell. Acta Pharmacol Sin 2001;22(10): 918-922.
9. Zhang Qingzhu（張慶柱）, Zhang Juntian. Effects of melatonin on the spatial and temporal changes of [Ca2+]i in single living cell of cortical neyrons by laser scanning confocal microscopy. Chin Med J 2000; 113(6):558-562.
10. Zhang Qingzhu（張慶柱）, Zhang Juntian. Antagonistic effects of melatonin on glutamate release and neurotoxicity in cerebral cortex. Acta Pharmacol Sin 1999; 20(9): 829-834
11. Zhang JT and Zhang QZ. Technology and Methodology of Neuropharmacological Research. 1st ed. People’s Medical Publishing House, 2005 (Chinese reference book).
12. Zhang QZ ed. Basic Pharmacology. 1st ed. Higher Education Press, 2006 (Chinese textbook).
13. Zhang QZ and Zhang JT. The Great Masters Creating World’s Modern Medical History—The Outstanding Achievement and Legendary Life of 105 Years’ Nobel Prize Winners in Physiology or Medicine. 1st ed. Chinese Academy of Medical Sciences & Peking Union Medical College (CAMS & PUMC) Press. 2006 (A Chinese book of popular medical sciences).
14. Zhang QZ ed. Molecular Pharmacology. 1st ed. Higher Education Press, 2007 (Chinese textbook).
15. Zhang JT，Zhang QZ and Zhang YX. Neuropharmacology. 1st ed. People’s Medical Publishing House, 2008 (Chinese reference book).
