基本介紹
- 中文名：崔京南
- 畢業院校：日本岡山大學
- 性別：男
- 職稱：教授，博士生導師
崔京南：男，大連理工大學、精細化工國家重點實驗室，教授，博士生導師
個人簡介
1978-1982年：畢業於東北電力學院、電廠化學專業，學士學位；
1992-1995年：畢業於日本岡山大學、套用化學專業，碩士學位；
1995-1998年：畢業於日本岡山大學、合成有機化學專業，博士學位；
1999-2006年：大連理工大學、精細化工國家重點實驗室，副教授；
2006-2007年：瑞典皇家工學院，化學系，訪問學者；
2007年--至今：大連理工大學、精細化工國家重點實驗室，教授，博士生導師
1992-1995年：畢業於日本岡山大學、套用化學專業，碩士學位；
1995-1998年：畢業於日本岡山大學、合成有機化學專業，博士學位；
1999-2006年：大連理工大學、精細化工國家重點實驗室，副教授；
2006-2007年：瑞典皇家工學院，化學系，訪問學者；
2007年--至今：大連理工大學、精細化工國家重點實驗室，教授，博士生導師
社會兼職
（1）J. Org. Chem.; （2）Tetrahedron Lett.; （3）Bioorg. Med. Chem.; （4）Int. J. Mol. Sci. 等學術期刊審稿人。
研究領域（研究課題）
1）芳香雜環化學和光化學；
2）生物酶催化合成有機化學
出版著作和論文
(31) A highly selective fluorescent ESIPT probe for the detection of human carboxylesterase 2 and its biological applications,
Lei Feng, Zhao-ming Liu, Guang-bo Ge, Xia Lv, Jie Hou, Jing Ning, Jing-nan Cui, Ling Yang.
Biosensors and Bioelectronics, 2015, 65, 9-15.
(30) A ratiometric fluorescent sensor for highly selective detection of human carboxylesterase 2 and its application in living cells.
Zhao-ming Liu, Lei Feng, Jie Hou, Xia Lv, Jing Ning, Guang-bo Ge, Ke-wei Wang, Jing-nan Cui, Ling Yang.
Sensors and Actuators B: Chemical. 2014, 205: 151–157.
(29) A highly selective long-wavelength fluorescent probe for human carboxylesterase 2 and its biomedical applications,
Lei Feng, Zhao-ming Liu, Guang-bo Ge, Liang Xu, Xia Lv, Jing Ning, Jie Hou, Jing-nan Cui, Ling Yang.
Chem. Commun., 2014, 50, 14519-14522.
(28) Quantitatively Mapping Cellular Viscosity with Detailed Organelle Information via a Designed PET Fluorescent Probe,
Tianyu Liu, Xiaogang Liu, David R. Spring, Xuhong Qian, Jingnan Cui, Zhaochao Xu,
Scientific Reports, 2014, DOI: 10.1038/srep05418.
(27) A highly selective ratiometric fluorescent probe for invitro monitoring and cellular imaging of human carboxylesterase1,
Liu ZM, Feng L, Ge GB, Lv X, Hou J, Cao YF, Cui JN, Yang L.
Biosensors and Bioelectronics, 2014, 57, 30–35.
(26) A red emission fluorescent probe for hydrogen sulfide and its application in living cells imaging，
Tao Chen, Yi Zheng, Zhaochao Xu*, Miao Zhao, Yongnan Xu, Jingnan Cui*，
Tetrahedron Letter，2013, 54, 2980-2982
(25) A Lysosome-Targetable Fluorescent Probe for Imaging Hydrogen Sulfide in Living Cells,
Tianyu Liu, Zhaochao Xu,* David R. Spring,* Jingnan Cui*,
Org. Lett., 2013, 15, 2310-2313.
(24) A two-photon fluorescent probe for imaging hydrogen sulfide in living cells,
Tianyu Liu, Xinfu Zhang, Qinglong Qiao, Chunyan Zou, Lei Feng, Jingnan Cui,* Zhaochao Xu,*
Dyes and Pigments, 2013, 99, 537-542.
(23) Rational design of fluorescent viscosity sensors by the principle of photoinduced electron transfer,
Zhiyong Wu, Jingnan Cui*, Xuhong Qian*,
Tetrahedron Lett., 2013, 54, 2575–2578.
(22) A fluorescent and colorimetric chemosensor for nitric oxide based on 1,8-naphthalimide,
Min Wang, Zhaochao Xu,* Xu Wang, Jingnan Cui,*
Dye and Pigments, 2013, 96, 333-337.
(21) A 4-aminonaphthalimide based environmentally sensitive fluorescence probe,
Zhi-Yong Wu, Jing-Nan Cui, Xu-Hong Qian, Tian-Yu Liu,
Chinese Chemical Letters. 2013, 24(5), 359-361.
(20) Novel acenaphthopyrazine derivatives as antitumor agents against MCF-7 cells: Molecular synthesis, optical properties, and DNA-binding studies,
Junling Xing, Jingnan Cui,* Shuang Wang, Jin Gao, Zhichao Zhang,
Monatsh Chem, 2012, 143, 243-250.
(19) A ratiometric and exclusively selective Cu-II fluorescent probe based on internal charge transfer (ICT),
Xiufu Chen, Jingyun Wang, Jingnan Cui,* Zhaochao Xu, Xiaojun Peng,*
?Tetrahedron, 2011, 67,?4869-4873.
(18) Zn2+-Triggered Amide Tautomerization Produces a Highly Zn2+-Selective, Cell-Permeable, and Ratiometric Fluorescent Sensor
Zhaochao Xu,* Kyung-Hwa Baek, Ha Na Kim, Jingnan Cui, Xuhong Qian, David R. Spring, Injae Shin,* ,Juyoung Yoon*
J. Am. Chem. Soc. 2010, 132, 601.
(17) A new class of organic dyes based on acenaphthopyrazine for dye-sensitized solar cells, Z. Kong, H. Zhou, J. Cui, T. Ma, X. Yang, L. Sun,
J. Photochem. Photobio. A: Chem. 2010, 213, 152-157.
(16) Preparation of chiral trans-5-substituted-acenaphthene-1,2-diols by baker’s yeast-mediated reduction of 5-substituted-acenaphthylene-1,2-diones,
L. Wang, X. Wang, J. Cui, W. Ren, N. Meng, X. Qian,
Tetrahedron: Asymmetry, 2010, 21, 825-830.
(15) Design, Synthesis and Bioactivity of Vinylnitro-cyano Neonicotinoids as Potential Insecticides,
K. Wang, X. Qian, J. Cui,
Monatsh. Chem. 2010, 141, 1117.
(14) One step from nitro to oxime: a convenient preparation of unsaturated oximes by the reduction of the corresponding vinylnitro compounds
Kewei Wang, Jingnan Cui, Xuhong Qian,*
Tetrahedron, 2009, 65, 10377.
(13) Novel acenaphtho[1,2-b]pyrrole-carboxylic acid family: synthesis, cytotoxicity, DNA-binding and cell cycle evaluation,
Lijuan Xie, Yi Xiao, Fang Wang, Yufang Xu, Xuhong Qian,* Rong Zhang, Jingnan Cui,* Jianwen Liu*
Bioorg. Med. Chem. 2009, 17, 7615.
(12) Synthesis of new amonafide analogues via coupling reaction and their cytotoxic evaluation and DNA-binding studies,
Lijuan Xie, Yufang Xu, Fang Wang, Jianwen Liu, Xuhong Qian,* Jingnan Cui *
Bioorg. Med. Chem. 2009, 17, 804.
(11) Novel Angular Furoquinolinones Bearing Flexible Chains as Antitumor Agents: Synthesis, Cytotoxic Evaluation and DNA-Binding Studies,
Lijuan Xie, Xuhong Qian,* Jingnan Cui,* Yi Xiao, Kewei Wang, Peichun Wu, Liying Cong
Bioorg. Med. Chem. 2008, 16, 8713.
(10) A Ratiometric and Highly Selective Fluorescent Sensor for Cadmium under Physiological pH Range: a New Strategy to Discriminate Cadmium from Zinc,
Chunliang Lu, Zhaochao Xu, Jingnan Cui,* Rong Zhang, Xuhong Qian;*
J. Org. Chem. 2007, 72，3554-3557.
(9) Molecular design, chemical synthesis, and biological evaluation of ‘4-1’ pentacyclic arylimidazonaphthalimides,
Feng Li, Jingnan Cui,* Lianying Guo, Xuhong Qian,* Weimin Ren, Kewei Wang, Fengyu Liu,
Boorg. Med. Chem. 2007, 15, 5114-51221.
(8) Baker’s yeast-mediated enantioselective reduction of substituted fluorenones,
Feng Li, Jingnan Cui,* Xuhong Qian,* Weimin Ren, Xingyong Wang
Chem. Commun., 2006, 865-867.
(7) Exploiting the deprotonation mechanism for the design of ratiometric and colorimetric Zn2+ fluorescent chemosensor with a large red-shift in emission,
Zhaochao Xu, Xuhong Qian,* Jingnan Cui,* Rong Zhang
Tetrahedron, 2006, 62, 100117-10122.
(6) Detecting Hg2+ ions with an ICT fluorescent sensor molecule: Remarkable emission spectra shift and unique selectivity,
Jiaobing Wang, Xuhong Qian,* Jingnan Cui
J. Org. Chem. 2006, 71, 4308-4311.
(5) Highly chemoselective reduction of aromatic nitro compounds to the corresponding hydroxylamines catalysed by plant cells from grape (Vitis vinifera L.),
Feng Li, Jingnan Cui,* Xuhong Qian,* Rong Zhang, Yi Xiao,
Chem. Commun., 2005, 1901-1903.
(4) A Colorimetric and Ratiometric Fluorescent Chemosensor With a Large Red-shift in Emission: Cu(II)-Only Sensing by Deprotonation of Secondary Amines as Receptor Conjugated to Naphthalimide Fluorophore,
Zhaochao Xu, Xuhong Qian,* Jingnan Cui,*
Org. Lett. 2005, 3029-3032.
(3) A Ratiometric and Selective Fluorescent Sensor for CuII Based on Internal Charge Transfer (ICT) ,
Zhaochao Xu, Yi Xiao, Xuhong Qian,* Jingnan Cui,* Dawei Cui,
Org. Lett. 2005, 889-892.
(2)A New Class of Long-Wavelength Fluorophores: Strong Red Fluorescence, Convenient Synthesis and Easy Derivation，
Yi Xiao, Fengyu Liu, Xuhong Qian,* Jingnan Cui,
Chem. Commun. 2005, 239-241.
(1) A novel strategy for the preparation of arylhydroxylamines: chemoselective reduction of aromatic nitro compounds using bakers’ yeast，
Feng Li, Jingnan Cui,* Xuhong Qian,* Rong Zhang,
Chem. Commun., 2004, 2338-2339.
Xiufu Chen, Jingyun Wang, Jingnan Cui,* Zhaochao Xu, Xiaojun Peng,*
?Tetrahedron, 2011, 67,?4869-4873.
(18) Zn2+-Triggered Amide Tautomerization Produces a Highly Zn2+-Selective, Cell-Permeable, and Ratiometric Fluorescent Sensor
Zhaochao Xu,* Kyung-Hwa Baek, Ha Na Kim, Jingnan Cui, Xuhong Qian, David R. Spring, Injae Shin,* ,Juyoung Yoon*
J. Am. Chem. Soc. 2010, 132, 601.
(17) A new class of organic dyes based on acenaphthopyrazine for dye-sensitized solar cells, Z. Kong, H. Zhou, J. Cui, T. Ma, X. Yang, L. Sun,
J. Photochem. Photobio. A: Chem. 2010, 213, 152-157.
(16) Preparation of chiral trans-5-substituted-acenaphthene-1,2-diols by baker’s yeast-mediated reduction of 5-substituted-acenaphthylene-1,2-diones,
L. Wang, X. Wang, J. Cui, W. Ren, N. Meng, X. Qian,
Tetrahedron: Asymmetry, 2010, 21, 825-830.
(15) Design, Synthesis and Bioactivity of Vinylnitro-cyano Neonicotinoids as Potential Insecticides,
K. Wang, X. Qian, J. Cui,
Monatsh. Chem. 2010, 141, 1117.
(14) One step from nitro to oxime: a convenient preparation of unsaturated oximes by the reduction of the corresponding vinylnitro compounds
Kewei Wang, Jingnan Cui, Xuhong Qian,*
Tetrahedron, 2009, 65, 10377.
(13) Novel acenaphtho[1,2-b]pyrrole-carboxylic acid family: synthesis, cytotoxicity, DNA-binding and cell cycle evaluation,
Lijuan Xie, Yi Xiao, Fang Wang, Yufang Xu, Xuhong Qian,* Rong Zhang, Jingnan Cui,* Jianwen Liu*
Bioorg. Med. Chem. 2009, 17, 7615.
(12) Synthesis of new amonafide analogues via coupling reaction and their cytotoxic evaluation and DNA-binding studies,
Lijuan Xie, Yufang Xu, Fang Wang, Jianwen Liu, Xuhong Qian,* Jingnan Cui *
Bioorg. Med. Chem. 2009, 17, 804.
(11) Novel Angular Furoquinolinones Bearing Flexible Chains as Antitumor Agents: Synthesis, Cytotoxic Evaluation and DNA-Binding Studies,
Lijuan Xie, Xuhong Qian,* Jingnan Cui,* Yi Xiao, Kewei Wang, Peichun Wu, Liying Cong
Bioorg. Med. Chem. 2008, 16, 8713.
(10) A Ratiometric and Highly Selective Fluorescent Sensor for Cadmium under Physiological pH Range: a New Strategy to Discriminate Cadmium from Zinc,
Chunliang Lu, Zhaochao Xu, Jingnan Cui,* Rong Zhang, Xuhong Qian;*
J. Org. Chem. 2007, 72，3554-3557.
(9) Molecular design, chemical synthesis, and biological evaluation of ‘4-1’ pentacyclic arylimidazonaphthalimides,
Feng Li, Jingnan Cui,* Lianying Guo, Xuhong Qian,* Weimin Ren, Kewei Wang, Fengyu Liu,
Boorg. Med. Chem. 2007, 15, 5114-51221.
(8) Baker’s yeast-mediated enantioselective reduction of substituted fluorenones,
Feng Li, Jingnan Cui,* Xuhong Qian,* Weimin Ren, Xingyong Wang
Chem. Commun., 2006, 865-867.
(7) Exploiting the deprotonation mechanism for the design of ratiometric and colorimetric Zn2+ fluorescent chemosensor with a large red-shift in emission,
Zhaochao Xu, Xuhong Qian,* Jingnan Cui,* Rong Zhang
Tetrahedron, 2006, 62, 100117-10122.
(6) Detecting Hg2+ ions with an ICT fluorescent sensor molecule: Remarkable emission spectra shift and unique selectivity,
Jiaobing Wang, Xuhong Qian,* Jingnan Cui
J. Org. Chem. 2006, 71, 4308-4311.
(5) Highly chemoselective reduction of aromatic nitro compounds to the corresponding hydroxylamines catalysed by plant cells from grape (Vitis vinifera L.),
Feng Li, Jingnan Cui,* Xuhong Qian,* Rong Zhang, Yi Xiao,
Chem. Commun., 2005, 1901-1903.
(4) A Colorimetric and Ratiometric Fluorescent Chemosensor With a Large Red-shift in Emission: Cu(II)-Only Sensing by Deprotonation of Secondary Amines as Receptor Conjugated to Naphthalimide Fluorophore,
Zhaochao Xu, Xuhong Qian,* Jingnan Cui,*
Org. Lett. 2005, 3029-3032.
(3) A Ratiometric and Selective Fluorescent Sensor for CuII Based on Internal Charge Transfer (ICT) ,
Zhaochao Xu, Yi Xiao, Xuhong Qian,* Jingnan Cui,* Dawei Cui,
Org. Lett. 2005, 889-892.
(2)A New Class of Long-Wavelength Fluorophores: Strong Red Fluorescence, Convenient Synthesis and Easy Derivation，
Yi Xiao, Fengyu Liu, Xuhong Qian,* Jingnan Cui,
Chem. Commun. 2005, 239-241.
(1) A novel strategy for the preparation of arylhydroxylamines: chemoselective reduction of aromatic nitro compounds using bakers’ yeast，
Feng Li, Jingnan Cui,* Xuhong Qian,* Rong Zhang,
Chem. Commun., 2004, 2338-2339.
作成果（獎勵、專利等）
獎勵：
（1）國家技術發明二等獎，2006年，大幅面數碼噴墨染料及其套用，彭孝軍、崔京南、張 蓉、王力成、樊江麗、王力軍；
（2）上海市自然科學一等獎，2008年，生物功能色素及螢光分子感測器，錢旭紅、肖 義、崔京南、徐玉芳；
專利：
（9）一種染料型中性墨水及其製備方法，ZL201310324975.5；
（8）一種以苊並吡嗪為母體的高靈敏性螢光探針、製備及套用，201210095991.7；
（7）一類鄰二氰基苊並吡嗪化合物及其抗腫瘤套用，ZL200910012748.2。
（6）手性2-羥基苊酮類化合物的製備方法，ZL200810033015.2；
（5）芳雜環基咪唑並萘醯亞胺類化合物及其套用，ZL200610046227.5；
（4）提高噴頭使用壽命的噴墨染料,ZL200510045835.X；
（3）4,5-雙取代-1,8-萘醯亞胺類化合物及其套用，ZL200410082745.3；
（2）水基噴墨染料，ZL03111517.9；
（1）一種萘醯亞胺螢光染料及其製備和套用，ZL201310160611.8;
