呂強，1978年4月出生，教授、博士生導師。蘇州大學紡織與工程學院教授。
基本介紹
- 中文名：呂強
- 出生日期：1978年4月
- 職業：蘇州大學紡織與工程學院教授
- 畢業院校：青島大學
人物經歷,研究方向,主要貢獻,代表性論文,科研項目,
人物經歷
本科1999年畢業於青島大學，2002年碩士研究生畢業於北京理工大學，2007年博士研究生畢業於清華大學，2007-2009年在美國Tufts大學David Kaplan研究組進行博士後研究，2009年11月進入現代絲綢國家工程實驗室（蘇州）工作至今。
現兼任中國材料研究學會理事和中國材料研究學會青年委員會理事。2009年底回國後已主持省部級以上項目5項，企業合作項目1項，其中包括國家自然科學基金面上項目1項，教育部博士點基金1項，江蘇省教育廳高校重大基礎科學項目1項，教育部歸國留學基金1項，企業合作攻關項目1項，作為學術骨幹參加973項目1項，總經費約250萬，在國內外知名刊物Biomaterials，Biomacromolecules，Acta Biomaterialia，Macromolecular Bioscience等已發表SCI研究論文36篇，申請國家發明專利8項。
研究方向
1.絲蛋白納米組裝及其性能調控的機制研究。
2.具有特異回響性的絲蛋白組裝修復材料的設計。
3.基於絲蛋白結構組裝的藥物控釋體系的設計。
4.絲蛋白調控的納米功能材料的製備。
主要貢獻
代表性論文
1.Qiang Lu*, Hesun Zhu, Cencen Zhang, Feng Zhang, Bing Zhang, David L Kaplan*, Silk-assembly mechanism and control-from thermodynamics to kinetics. Biomacromolecules,2012, 13, 826-832.
2.Feng Zhang, Baoqi Zuo,Zhihai Fan, Zonggang Xie, Qiang Lu*, Xueguang Zhang*. Mechanisms and control of silk-based electrospinning. Biomacromolecules,2012,13,798-804.
3.Xingliang He, Xiaowei Huang, Qiang Lu*, Shuling Bai*, Hesun Zhu, Nanoscale control of silks for regular hydroxyapatite formation. Progress in Natural science: Materials International(In press).
4.Aili Zhang, Yu Tu, Songbing Qin, Yan Li, Juying Zhou, Na Chen, Qiang Lu, Bingbo Zhang, Gold nanoclusters as contrast agents for fluorescent and X-ray dual-modality imaging. Journal of Colloid and Interface Science, 2012, 372, 239-244.
5.Qiang Lu*, Xiaoqin Wang, Hesun Zhu, David L Kaplan. Surface immobilization of antibody on silk fibroin through conformational transition.Acta Biomaterialia, 2011, 7, 2782-2786.
6.Qiang Lu*, Yongli Huang, Mingzhong Li, Baoqi Zuo, Shenzhou Lu, Jiannan Wang, Hesun Zhu, David L Kaplan. Silk fibroin electrogelation mechanisms. Acta Biomaterialia, 2011, 7, 2394-2400.
7.Qiang Lu*, Bing Zhang, Mingzhong Li, Baoqi Zuo, David L Kaplan, Yongli Huang, Hesun Zhu. Degradation Mechanism and control of silk fibroin, Biomacromolecules, 2011, 12, 1080-1086.
8.Qiang Lu*, Xiuli Wang, Shenzhou Lu, Mingzhong Li, David L Kaplan, Hesun Zhu, Nanofibrous architecture of silk fibroin scaffolds prepared with a mild self-assembly process, Biomaterials, 2011, 32, 1059-1067.
9.黃永利，呂強*，李明忠*，張冰，朱鶴孫，電場調控載藥絲素蛋白微球的製備，科學通報，2011，56, 1013-1018.
10.Qiang Lu, Xiaoqin Wang, Xiao Hu, Peggy Cebe, Fiorenzo Omenetto, David L Kaplan. Stabilization and release of enzymes from silk films. Macromolecular Bioscience, 2010，10， 359-368.
11.Qiang Lu, Xiaohui Zhang, Xiao Hu, David L Kaplan. Green process to prepare silk/gelatin biomaterial scaffolds. Macromolecular Bioscience, 2010, 10, 289-298.
12.Qiang Lu, Xiao Hu, Xiaoqin Wang, Jonathan A Kluge, Shenzhou Lu, Peggy Cebe, David L Kaplan. Water-insoluble silk films with silk I structure. Acta Biomaterialia, 2010, 6, 1380-1387.
13.Xiao Hu, Qiang Lu, Lin Sun, Peggy Cebe, Xiaoqin Wang, Xiaohui Zhang, David L Kaplan. Biomaterials from ultrasonication-induced silk fibroin-hyaluronic acid hydrogels. Biomacromolecules, 2010, 11, 3178-3188.
14.Gary G Leisk, Tim J Lo, Tuna Yucel, Qiang Lu, David L Kaplan. Electrogelation for protein adhesives. Advanced Materials, 2010, 21, 711-715.
15.Shenzhou Lu, Xiaoqin Wang, Qiang Lu, Xiaohui Zhang, Jonathan A Kluge, Neha Uppal, Fiorenzo Omenetto, David L Kaplan. Insoluble and flexible silk films containing glycerol. Biomacromolecules, 2010, 11, 143-150.
16.Xiaoqin Wang, Tuna Yucel, Qiang Lu, Xiao Hu, David L Kaplan. Silk nanospheres and microspheres from silk/pva blend films for drug delivery, Biomaterials, 2010, 31, 1025-1035.
17.Xiao Hu, Qiang Lu, David L Kaplan, Peggy Cebe. Microphase separation controlled β-sheet crystallization kinetics in fibrous proteins. Macromolecules, 2009, 42, 2079-2087.
18.Qiang Lu, Kun Hu, Qingling Feng, Fuzhai Cui. Growth of fibroblast and vascular smooth muscle cells in fibroin/collagen scaffold. Materials Science and Engineering C, 2009, 29, 2239-2245.
19.Shenzhou Lu, Xiaoqin Wang, Qiang Lu, Xiao Hu, Neha Uppal, Fiorenzo G Omenetto, David L Kaplan. Stabilization of enzymes in silk films.Biomacromolecules, 2009, 10, 1032-1042.
20.Qiang Lu, Qingling Feng, Kun Hu, Fuzhai Cui. Preparation of three-dimensional fibroin/collagen scaffolds in various pH conditions. Journal of Materials Science-Materials in Medicine, 2008, 19, 629-634.
21.Qiang Lv, Kun Hu, Qingling Feng, Fuzai Cui. Fibroin/collagen hybrid hydrogels with crosslinking method: preparation, properties, and cytocompatibility. Journal of Biomedical Mateirals Research Part A, 2008, 84A, 198-207.
22.Kun Hu, Fuzai Cui, Qiang Lu, Jun Ma, Qingling Feng. Preparation of fibroin/recombinant human-like collagen scaffold to promote fibroblasts compatibility. Journal of Biomedical Materials Research Part A, 2008, 84A, 483-490.
23.Qiang Lu, Kun Hu, Qingling Feng, Fuzai Cui. Preparation of insoluble fibroin/collagen films without methanol treatment and the increase of its flexibility and cytocompatibility. Journal of Applied polymer Science, 2008, 109, 1577-1584.
24.Qiang Lu, Shejia Zhang, Kun Hu, Qingling Feng, Chuanbao Cao, Fuzhai Cui. Cytocompatibility and blood compatibility of multifunctional fibroin/collagen/heparin scaffolds. Biomaterials, 2007, 28, 2306-2313.
25.Qiang Lv, Kun Hu, Qingling Feng, Fuzhai Cui, Chuanbao Cao. Preparation and characterization of PLA/fibroin composite and culture of HepG2 (human hepatocellular liver carcinoma cell line) cells. Composites Science and Technology, 2007, 67, 3023-3030.
26.K Hu, Q Lv, FZ Cui, L Xu, YP Jiao, Y Wang, QL Feng, HL Wang, LY Huang. A novel poly(L-lactide) (PLLA)/fibroin hybrid scaffold to promote hepatocyte viability and decrease macrophage responses. Journal of Bioactive and Compatible Polymers, 2007, 22, 395-410.
2.Feng Zhang, Baoqi Zuo,Zhihai Fan, Zonggang Xie, Qiang Lu*, Xueguang Zhang*. Mechanisms and control of silk-based electrospinning. Biomacromolecules,2012,13,798-804.
3.Xingliang He, Xiaowei Huang, Qiang Lu*, Shuling Bai*, Hesun Zhu, Nanoscale control of silks for regular hydroxyapatite formation. Progress in Natural science: Materials International(In press).
4.Aili Zhang, Yu Tu, Songbing Qin, Yan Li, Juying Zhou, Na Chen, Qiang Lu, Bingbo Zhang, Gold nanoclusters as contrast agents for fluorescent and X-ray dual-modality imaging. Journal of Colloid and Interface Science, 2012, 372, 239-244.
5.Qiang Lu*, Xiaoqin Wang, Hesun Zhu, David L Kaplan. Surface immobilization of antibody on silk fibroin through conformational transition.Acta Biomaterialia, 2011, 7, 2782-2786.
6.Qiang Lu*, Yongli Huang, Mingzhong Li, Baoqi Zuo, Shenzhou Lu, Jiannan Wang, Hesun Zhu, David L Kaplan. Silk fibroin electrogelation mechanisms. Acta Biomaterialia, 2011, 7, 2394-2400.
7.Qiang Lu*, Bing Zhang, Mingzhong Li, Baoqi Zuo, David L Kaplan, Yongli Huang, Hesun Zhu. Degradation Mechanism and control of silk fibroin, Biomacromolecules, 2011, 12, 1080-1086.
8.Qiang Lu*, Xiuli Wang, Shenzhou Lu, Mingzhong Li, David L Kaplan, Hesun Zhu, Nanofibrous architecture of silk fibroin scaffolds prepared with a mild self-assembly process, Biomaterials, 2011, 32, 1059-1067.
9.黃永利，呂強*，李明忠*，張冰，朱鶴孫，電場調控載藥絲素蛋白微球的製備，科學通報，2011，56, 1013-1018.
10.Qiang Lu, Xiaoqin Wang, Xiao Hu, Peggy Cebe, Fiorenzo Omenetto, David L Kaplan. Stabilization and release of enzymes from silk films. Macromolecular Bioscience, 2010，10， 359-368.
11.Qiang Lu, Xiaohui Zhang, Xiao Hu, David L Kaplan. Green process to prepare silk/gelatin biomaterial scaffolds. Macromolecular Bioscience, 2010, 10, 289-298.
12.Qiang Lu, Xiao Hu, Xiaoqin Wang, Jonathan A Kluge, Shenzhou Lu, Peggy Cebe, David L Kaplan. Water-insoluble silk films with silk I structure. Acta Biomaterialia, 2010, 6, 1380-1387.
13.Xiao Hu, Qiang Lu, Lin Sun, Peggy Cebe, Xiaoqin Wang, Xiaohui Zhang, David L Kaplan. Biomaterials from ultrasonication-induced silk fibroin-hyaluronic acid hydrogels. Biomacromolecules, 2010, 11, 3178-3188.
14.Gary G Leisk, Tim J Lo, Tuna Yucel, Qiang Lu, David L Kaplan. Electrogelation for protein adhesives. Advanced Materials, 2010, 21, 711-715.
15.Shenzhou Lu, Xiaoqin Wang, Qiang Lu, Xiaohui Zhang, Jonathan A Kluge, Neha Uppal, Fiorenzo Omenetto, David L Kaplan. Insoluble and flexible silk films containing glycerol. Biomacromolecules, 2010, 11, 143-150.
16.Xiaoqin Wang, Tuna Yucel, Qiang Lu, Xiao Hu, David L Kaplan. Silk nanospheres and microspheres from silk/pva blend films for drug delivery, Biomaterials, 2010, 31, 1025-1035.
17.Xiao Hu, Qiang Lu, David L Kaplan, Peggy Cebe. Microphase separation controlled β-sheet crystallization kinetics in fibrous proteins. Macromolecules, 2009, 42, 2079-2087.
18.Qiang Lu, Kun Hu, Qingling Feng, Fuzhai Cui. Growth of fibroblast and vascular smooth muscle cells in fibroin/collagen scaffold. Materials Science and Engineering C, 2009, 29, 2239-2245.
19.Shenzhou Lu, Xiaoqin Wang, Qiang Lu, Xiao Hu, Neha Uppal, Fiorenzo G Omenetto, David L Kaplan. Stabilization of enzymes in silk films.Biomacromolecules, 2009, 10, 1032-1042.
20.Qiang Lu, Qingling Feng, Kun Hu, Fuzhai Cui. Preparation of three-dimensional fibroin/collagen scaffolds in various pH conditions. Journal of Materials Science-Materials in Medicine, 2008, 19, 629-634.
21.Qiang Lv, Kun Hu, Qingling Feng, Fuzai Cui. Fibroin/collagen hybrid hydrogels with crosslinking method: preparation, properties, and cytocompatibility. Journal of Biomedical Mateirals Research Part A, 2008, 84A, 198-207.
22.Kun Hu, Fuzai Cui, Qiang Lu, Jun Ma, Qingling Feng. Preparation of fibroin/recombinant human-like collagen scaffold to promote fibroblasts compatibility. Journal of Biomedical Materials Research Part A, 2008, 84A, 483-490.
23.Qiang Lu, Kun Hu, Qingling Feng, Fuzai Cui. Preparation of insoluble fibroin/collagen films without methanol treatment and the increase of its flexibility and cytocompatibility. Journal of Applied polymer Science, 2008, 109, 1577-1584.
24.Qiang Lu, Shejia Zhang, Kun Hu, Qingling Feng, Chuanbao Cao, Fuzhai Cui. Cytocompatibility and blood compatibility of multifunctional fibroin/collagen/heparin scaffolds. Biomaterials, 2007, 28, 2306-2313.
25.Qiang Lv, Kun Hu, Qingling Feng, Fuzhai Cui, Chuanbao Cao. Preparation and characterization of PLA/fibroin composite and culture of HepG2 (human hepatocellular liver carcinoma cell line) cells. Composites Science and Technology, 2007, 67, 3023-3030.
26.K Hu, Q Lv, FZ Cui, L Xu, YP Jiao, Y Wang, QL Feng, HL Wang, LY Huang. A novel poly(L-lactide) (PLLA)/fibroin hybrid scaffold to promote hepatocyte viability and decrease macrophage responses. Journal of Bioactive and Compatible Polymers, 2007, 22, 395-410.
科研項目
1. 絲蛋白基肛瘺修補塞的開發（橫向項目，150萬）。
2. 絲蛋白三維微納結構的構建及其對細胞生長和分化的作用（國家自然科學基金面上項目，63萬）。
3. 具有骨誘導性的仿生功能性絲蛋白人工骨的構建（江蘇省教育廳高校基礎研究重大項目，7.5萬）。
4.納米化絲素蛋白調控碳酸鈣生物礦化的機制研究（ 教育部博士點新教師基金，3.6萬）。
5.保持生長因子活性的絲蛋白多孔支架製備和套用（教育部歸國留學人員啟動基金，4.2萬）。
6.幹細胞與絲蛋白生物材料在仿生功能性皮膚構建及其運用中的作用機制（973項目子課題，50萬，課題子方向負責人）
