龔芸(Yun Gong) 醫生是美國德克薩斯大學MD安德森癌症中心（The University of Texas MD Anderson Cancer Center, Houston, Texas,USA）病理學終身教授（Professor with Tenure）
基本介紹
- 中文名：龔芸
- 外文名：Yun Gong, M. D
- 畢業院校：浙江醫科大學 (現浙江大學醫學院)
- 學歷：醫學博士
簡介,學習及工作經歷,學術成果,學術兼職,Selected Publications,Peer-Reviewed Original Research Articles,Invited Articles,Book Chapters,Books (edited and written),Letters to the Editor,
簡介
龔芸(Yun Gong)醫生是美國德克薩斯大學MD安德森癌症中心 (The University of Texas MD Anderson Cancer Center, Houston, Texas, USA)病理學終身教授 (Professor with Tenure)。
學習及工作經歷
1979年至1984 年就讀於浙江醫科大學 (現浙江大學醫學院)醫療系, 畢業後留校在組胚教研組任助教兩年。
1986年考取該校病理專業研究生，並於1989年獲碩士學位。
1989至1990 在中科院上海細胞所從事人-鼠單抗研究。
1991年前往荷蘭, 在 Department of Molecular and Developmental Genetics, Catholic University of Nijmegen從事分子遺傳學研究。
自1994起, 先後在美國加州大學聖地亞哥分校的醫學中心以及The Scripps Research Institute從事蛋白受體與心血管疾病發病機理的研究。
1998年至2002年，在芝加哥西北大學 (Northwestern University) 接受解剖病理和臨床病理住院醫培訓。繼而在休斯頓的德克薩斯大學MD安德森癌症中心接受細胞病理學Fellowship專業培訓並留院工作至今。
學術成果
龔芸醫生的主要研究領域是細胞學診斷和發展。她也熱衷於乳腺癌生物指標的穩定性與靶向治療關係的研究以及探索與乳腺癌個性化診斷治療有關的可行性研究。迄今，已發表學術論文120篇,包括柳葉刀·腫瘤 (Lancet Oncology)，美國醫學會會刊 (JAMA)，美國 臨床腫瘤學雜誌 (Journal of Clinical Oncology) 和癌症期刊 (Cancer), 特邀綜述或評論18篇，會議摘要118篇, 獨立出書1本, 參與編寫書籍章節6部。她是MD安德森癌症中心多項乳腺癌科題的負責人或重要合作人, 參與乳腺癌基礎研究和臨床試驗課題二十餘項。她參與的炎性乳癌課題獲兩個Susan G. Komen Promise Grant資助。
學術兼職
龔芸醫生是美國加拿大病理學院 (United States and Canadian Academy of Pathology, USCAP), 美國細胞病理學協會(American Society of Cytopathology, ASC)， 美國病理學家協會(College of American Pathologists, CAP)和全美華人病理學會 (Chinese American Pathologists Association, CAPA)會員。她擔任或曾經擔任美國細胞病理學協會的Editorial Review Board和 Scientific Program Committee(學術籌劃委員會 )成員， 全美華人病理學會教育學術委員會主席，全美華人病理學會副主席。2017年2月當選為全美華人病理學會候任主席。
龔芸醫生美國國立癌症研究所(NCI)/國立衛生研究院(NIH) 科研基金評審委員會的評審，MD安得森癌症中心科研基金評審委員會 和Credentials Committee of the Medical Staff成員，她是Cancer Cytopathology, Diagnostic Cytopathology, World Journal of Clinical Oncology和 International Journal of Clinical and Experimental Pathology等雜誌的編委或執行編委成員, 是Breast Diseases: A Year Book Quarterly的客座編輯, 受邀為17個病理學或腫瘤學雜誌審稿。她組織或參與過多個在美國, 歐洲和中國召開的病理國際或國內學術會議。她連續多年被列入Marquis Who'sWho in America, Marquis Who'sWho in the World, Marquis Who'sWho in American Women和 Best Doctors in America。
Selected Publications
Peer-Reviewed Original Research Articles
1. Chen YJ, Lin CY Feng J, Cogdell D, Zhang W, Liu J, Sneige N, Gong Y, Guo M. Accuracy of EasyChip HPV Blot Genotyping Assay to Detect High-Risk HPV Genotypes in SurePath Pap Specimens. Journal of the American Society of Cytopathology. In Press.
2. Kandukuri S, Lin F, Gui L, Gong Y, Fan F, Chen L, Cai G, Liu H. Application of immunohistochemistry in undifferentiated neoplasms: a case-based approach. Arch Pathol Lab Med. In Press.
3. *Zhou H, Guo M, Gong Y. Challenge of fine needle aspiration diagnosis of angiomyolipoma: a study of 33 cases. Cancer Cytopathology. In Press.
4. Alexander A, Karakas C, Chen X, Carey J, Yi M, Bondy M, Thompson P, Cheung L, Ellis LO, Gong Y, Krishnamurthy S, Alvarez R, Ueno NT, Hunt KK, Keyomarsi K. Cyclin E Overexpression as a Biomarker for Combination Treatment Strategies in Inflammatory Breast Cancer. Oncotarget. In Press.
5. Wang H, Hoda RS, Faquin W, Rossi ED, Hotchandani N, Sun T, Pusztaszeri M, Bizzarro T, Bongiovanni M, Patel V, Jhala N, Gong Y. Fine-needle aspiration biopsy of secondary nonlymphomatous malignancies in salivary glands: A multi-institutional study of 184 cases. Cancer Cytopathol. In Press.
6. Sneige N, Hess KR, Multani AS, Gong Y, Ibrahim NK. Prognostic significance of equivocal HER2 results and clinical utility of alternative chromosome 17 genes in patients with breast cancer: a cohort study. Cancer. In Press.
7. Wang X, Reyes ME, Zhang D, Funakoshi Y, Trape AP, Gong Y, Kogawa T, Eckhardt BL, Masuda H, Pirman DA, Yang P, Reuben JM, Woodward W, Bartholomeusz C, Hortobagyi GN, Tripathy D, Ueno NT. The EGFR/COX-2/TGFβ signaling axis promotes the progression of inflammatory breast cancer through the regulation of cancer stem-like cells. Oncotarget. In Press.
8. *Leng B, Guo M, Zhao J, Gong Y. Utility and Pitfalls of GATA3 Immunocytochemistry for Diagnosis of Metastatic Breast Carcinoma and Urothelial Carcinoma on Cytology Specimens. Journal of the American Society of Cytopathology. In Press.
9. Guo M, Khanna A, Dawlett M, Patel S, Gong Y, Staerkel G. Efficacy of reflex HPV16/18 genotyping in predicting CIN3/VAIN3 in women with HPV+/Pap– results. Journal of the American Society of Cytopathology 5:31-36, 2016.
10. Kono M, Fujii T, Lyons GR, Huo L, Bassett R, Gong Y, Karuturi MS, Tripathy D, Ueno NT. Impact of androgen receptor expression in fluoxymesterone-treated estrogen receptor-positive metastatic breast cancer refractory to contemporary hormonal therapy. Breast Cancer Res Treat 160:101-09, 2016. PMID: 27663436.
11. Huo L, Wang Y, Gong Y, Krishnamurthy S, Wang J, Diao L, Liu CG, Liu X, Lin F, Symmans WF, Wei W, Zhang X, Sun L, Alvarez RH, Ueno NT, Fouad TM, Harano K, Debeb BG, Wu Y, Reuben J, Cristofanilli M, Zuo Z. MicroRNA Expression Profiling Identifies Decreased Expression of miR-205 in Inflammatory Breast Cancer. Mod Pathol 29:330-42, 2016. PMID: 26916073.
12. Arun BK, Gong Y, Liu D, Litton JK, Gutierrez-Barrera AM, Jack Lee J, Vornik L, Ibrahim NK, Cornelison T, Hortobagyi GN, Heckman-Stoddard BM, Koenig KB, Alvarez RR, Murray JL, Valero V, Lippman SM, Brown P, Sneige N. Phase I biomarker modulation study of atorvastatin in women at increased risk for breast cancer. Breast Cancer Res Treat 158:67-77, 2016. PMID: 27287781.
13. Diaz De Vivar A, Dawlett M, Wang JP, Jack A, Gong Y. Staerkel G, Guo M. Clinical performance of hybrid capture 2 HPV testing for recurrent high-grade cervical/vaginal intraepithelial neoplasm in patients with an ASC-US Pap result during long-term post-therapy follow-up monitoring. Arch Pathol Lab Med 139:219-224, 2015. PMID: 25611104.
14. Huo L, Gong Y, Guo M, Gilcrease MZ, Wu Y, Zhang H, Zhang, J, Resetkova E, Hunt KK, Deavers MT. GATA-binding protein 3 enhances the utility of gross cystic disease fluid protein-15 and mammaglobin A in triple-negative breast cancer by immunohistochemistry. Histopathol 67:245-254, 2015. PMID: 25564996.
15. Lacerda L, Debeb BG, Smith D, Larson R, Solley T, Xu W, Krishnamurthy S, Gong Y, Levy LB, Buchholz T, Ueno NT, Klopp A, Woodward WA. Mesenchymal stem cells mediate the clinical phenotype of inflammatory breast cancer in a pre-clinical model. Breast Cancer Res 17:48, 2015. PMCID: PMC4389342.
16. Tsai CJ, Li J, Gonzalez-Angulo AM, Allen PK, Woodward WA, Ueno NT, Lucci A, Krishnamurthy S, Gong Y, Yang W, Cristofanilli M, Valero V, Buchholz, TA. Outcomes after multidisciplinary treatment of inflammatory breast cancer in the era of neoadjuvant HER2-directed therapy. Am J Clin Oncol 38:242-7, 2015. PMCID: PMC3880388.
17. Mallampati S, Leng X, Ma H, Zeng J, Li J, Wang H, Lin K, Lu Y, Yang Y, Sun B, Gong Y, Lee J, Konopleva M, Andreeff M, Arlinghaus RB, Cai Z, Fang B, Shen H, Han X, Hirsch-Ginsberg CF, Gao X, Paranjape AN, Mani SA, Clise-Dwyer K, Sun X. Tyrosine kinase inhibitors induce mesenchymal stem cell-mediated resistance in BCR-ABL+ acute lymphoblastic leukemia. Blood 125:2968-2973, 2015. PMID: 25712988.
18. *Gong Y, Wang J, Huo L, Wei W, Ueno NT, Woodward WA. Aldehyde dehydrogenase 1 (ALDH1) expression in inflammatory breast cancer as measured by immunohistochemical staining. Clin Breast Cancer 14:e81-8, 2014. PMID: 24461456.
19. Woodward WA, Krishnamurthy S, Lodhi A, Xiao L, Gong Y, Cristofanilli M, Buchholz TA, Lucci A. Aldehyde dehydrogenase 1 immunohistochemical staining in primary breast cancer cells independently predicted overall survival but did not correlate with the presence of circulating or disseminated tumors cells. J Cancer 5:360-7, 2014. PMCID: PMC4007524.
20. Guo M, Khanna A, Feng J, Patel S, Zhang W, Gong Y, Huo L, Staerkel G. Analytical performance of cervista HPV 16/18 in SurePath pap specimens. Diagn Cytopathol 43:301-6, 2014. PMCID: PMC25352375.
21. Guo M, Khanna A, Dhillon J, Patel S, Feng J, Williams MD, Bell DM, Gong Y, Katz, RL, Sturgis EM, Staerkel GA. Cervista HPV assays for fine-needle aspiration specimens are a valid option for human papillomavirus testing in patients with oropharyngeal carcinoma. Cancer Cytopathol 122:96-103, 2014. PMID: 24339259.
22. Singh M, Ding Y, Zhang L, Song D, Gong Y, Adams S, Ross DS, Wang J, Gorover S, Doval DC, Shao C, He Z, Chang V, Deng FM, Zhang D, Zu R, Lee P. Distinct breast cancer subtypes in women with early-onset disease across races. Am J Cancer Res 4:337-52, 2014. PMCID: PMC4106652.
23. *Gong Y, Wei Y, Wu Y, Ueno NT, Huo L. Expression of androgen receptor in inflammatory breast cancer and its clinical relevance. Cancer 120:1775-9, 2014. PMID: 24634055.
24. Debeb B, Gong Y, Atkinson R, Sneige N, Huo L, Gonzalez-Angulo A, Hung M, Valero V, Ueno N, Woodward W. EZH2 expression correlates with locoregional recurrence after radiation in inflammatory breast cancer. J Exp Clin Cancer Res 33:58, 2014. PMID: 25051981.
25. Liu H, Shi J, Prichard JW, Gong Y, Lin F. Immunohistochemical evaluation of GATA-3 expression in ER-negative breast carcinomas. Am J Clin Pathol 141:648-55, 2014. PMID: 24713735.
26. Mallampati S, Sun B, Lu Y, Ma H, Gong Y, Wang D, Lee JS, Lin K, Sun X. Integrated genetic approaches identify the molecular mechanism of SOX4 in early B-cell development: intricate roles for RAG1/2 and CK1ε. Blood 123:4064-76, 2014. PMCID: PMC4073324.
27. Liao B, Kamiya-Matsuoka C, Gong Y, Chen M, Wolf BA, Fowler NH. Primary natural killer/T-cell lymphoma presenting as leptomeningeal disease. J Neurol Sci 343(1-2):46-50, 2014. PMID: 24880537.
28. *Clevenger J, Joseph C, Dawlett M, Guo M, Gong Y. Reliability of immunostaining using pan-melanoma cocktail, SOX10, and MITF in confirming a diagnosis of melanoma on fine-needle aspiration smears. Cancer Cytopathol 122:779-85, (Featured Article), 2014. PMID: 24954720.
29. Ma H, Mallampati S, Lu Y, Sun B, Wang E, Leng X, Gong Y, Shen H, Yin CC, Jones D, Amin HM, You MJ, Zweidler-McKay P, Ma Y, Kantarjian HM, Arlinghaus RB, Glassman A, Sun X. Sox4/Tcf711 Axis promotes progression of BCR-ABL+Acute lymphoblastic leukemia. Haematologica 99:1591-8, 2014. PMID: 24997151.
30. *Zhang YH, Liu CJ, Dawlett M, Guo M, Sun X, Gong Y. The role of SOX11 immunostaining in confirming the diagnosis of mantle cell lymphoma on fine-needle aspiration samples. Cancer Cytopathol 122:892-7, 2014. PMID: 25056830.
31. *Wang J, Katz RL, Stewart J, Landon G, Guo M, Gong Y.. Fine needle aspiration diagnosis of lymphomas with signet ring cell features: a potential pitfalls and solutions. Cancer Cytopathol 121:525-32, (Featured Article), 2013. PMID: 23536424.
32. Huo L, Zhang J, Gilcrease MZ, Gong Y, Wu Y, Zhang H, Resetkova E, Hunt KK, Deavers MT. Gross cystic disease fluid protein-15 and mammaglobin A expression determined by immunohistochemistry is of limited utility in triple-negative breast cancer. Histopathol 62:267-74, 2013. PMCID: PMC3881372.
33. Guo M, Gong Y, Wang J, Dawlett M, Patel S, Liu P, Bevers TB, Sneige N.. HPV 16/18 Genotyping Can Improve Risk Profiling in Women with Mildly Abnormal Pap Results. Cancer Cytopathol 121:79-85, 2013. PMID: 23225501.
34. Atiq M, Bhutani MS, Ross WA, Raju GS, Gong Y, Tamm EP, Javle M, Wang X, Lee JH.. Role of Endoscopic Ultrasonography in Evaluation of Metastatic Lesions to the Pancreas: A Tertiary Cancer Center Experience. Pancreas 42:516-23, 2013. PMID: 23211369.
35. Sun B, Mallampati S, Gong Y, Wang D, Lefebvre V, Sun X. Sox4 is required for the survival of pro-B cells. J Immunol 190:2080-89, 2013. PMCID: PMC3578124.
36. Krishnamurthy S, Woodward W, Yang W, Reuben JM, Tepperberg J, Ogura D, Niwa S, Huo L, Gong Y, El-Zein R, Gonzalez-Angulo AM, Chavez Mac Gregor M, Alvarez R, Lucci A, Valero V, Ueno NT. Status of the anaplastic lymphoma kinase (ALK) gene in inflammatory breast carcinoma. SpringerPlus 2:409, 2013. PMCID: PMC3797914.
37. Wang X, Saso H, Iwamoto T, Xia W, Gong Y, Pusztai L, Woodward WA, Reuben JM, Warner SL, Bearss DJ, Hortobagyi GN, Hung MC, Ueno NT. Tazarotene-induced gene 1 promotes tumorigenicity and invasiveness of inflammatory breast cancer through receptor tyrosine kinase axl. Cancer Res 73:6516-25, 2013. PMID: 24014597.
38. Li X, Deavers MT, Guo M, Liu P, Gong Y, Albarracin CT, Middleton LP, Huo L.. The effect of prolonged cold ischemia time on estrogen receptor immunohistochemistry in breast cancer. Mod Pathol 26:71-8, 2013. PMCID: PMC3881416.
39. Zhao L, Gong Y, Wang J, Dawlett M, Huo L, Caraway NP, Guo M. Ultrasound-guided fine-needle aspiration biopsy of thyroid bed lesions from patients with thyroidectomy for thyroid carcinomas. Cancer Cytopathol 121:101-7, 2013. PMID: 22605565.
40. Yang Y, Mallampati S, Sun B, Zhang J, Kim SB, Lee JS, Gong Y, Cai Z, Sun X. Wnt pathway contributes to the protection by bone marrow stromal cells of acute lymphoblastic leukemia cells and is a potential therapeutic target. Cancer Lett 333:9-17, 2013. PMCID: PMC3880833.
41. Zhang J, Li G, Li Z, Yu X, Zheng Y, Jin K, Wang H, Gong Y, Sun X, Teng X, Cao J, Teng L. Estrogen-independent effects of ER-α36 in ER-negative breast cancer. Steroids 77:666-73, 2012. PMID: 22402113.
42. Atiq M, Bhutani MS, Bektas M, Lee JE, Gong Y, Tamm EP, Shah CP, Ross WA, Yao J, Raju GS, Wang X, Lee JH.. EUS-FNA for Pancreatic Neuroendocrine Tumors - A tertiary cancer center experience. Dig Dis Sci 57:791-800, 2012. PMID: 21964743.
43. *Kundu UR, Guo M, Landon G, Wu Y, Sneige N, Gong Y. Fine needle aspiration cytology of sclerosing adenosis of the breast: a retrospective review of cytologic features in conjunction with corresponding histologic features and radiologic findings. Am J Clin Pathol 138:96-102, 2012. PMID: 22706864.
44. Niikura N, Liu J, Hayashi N, Mittendorf EA, Gong Y, Palla SL, Tokuda Y, Gonzalez-Angulo AM, Hortobagyi GN, Ueno NT.. Loss of HER2 expression in metastatic sites of HER2-overexpressing primary breast tumors. J Clin Oncol 30:593-9, 2012. PMCID: PMC3295557.
45. Alvarez RH, Gong Y, Ueno NT, Alizadeh PA, Hortobagyi GN, Valero V. Metastasis in the Breast Mimicking Inflammatory Breast Cancer. J Clin Oncol 30:e202-6, 2012. PMID: 22734030.
46. Atiq M, Gong Y, Raju GS, Lee JH.. Pancreatic endocrine microadenomatosis in a patient with oculo-facio-cardio-dental syndrome (OFCD). Pancreas 41:327-29, 2012. PMID: 22343980.
47. Zhao Q, Rashid A, Gong Y, Katz MH, Lee JE, Wolf R. Balachandran A, Varadhachary GR, Pisters PWT, Wang H, Gomez HF, Abbruzzese JL, Fleming JB, Wang H.. Pathologic Complete Response to Neoadjuvant Therapy in Patients with Pancreatic Ductal Adenocarcinoma Is Associated with Better Prognosis. Ann Diagn Pathol 16:29-37, 2012. PMCID: PMC3832988.
48. Sneige N, Thomison JB, Malpica A, Gong Y, Ensor J, Silva EG. Peritoneal washing cytologic analysis of ovarian serous tumors of low malignant potential to detect peritoneal implants and predict clinical outcome. Cancer Cytopathol 120:238-44, 2012. PMCID: PMC3867290.
49. Kurian EM, Dawlett M, Wang J, Gong Y, Guo M.. The triage efficacy of fine needle aspiration biopsy for follicular variant of papillary thyroid carcinoma using the Bethesda reporting guidelines. Diagn Cytopathol 40:E69-73, 2012. PMID: 21538966.
50. Arias-Pulido H, Chaher N, Gong Y, Qualls C, Vargas J, Royce M.. Tumor stroma vascular endothelial growth factor A is predictive of poor outcome in inflammatory breast cancer. BMC Cancer 12:298, 2012. PMCID: PMC3474178.
51. Antic T, Gong Y, Sneige N.. Tumor type and single-cell/mesothelial-like cell pattern of breast carcinoma metastases in pleural and peritoneal effusions. Diagn Cytopathol 40:311-15, 2012. PMID: 21104845.
52. *Zhao L, Guo M, Sneige N, Gong Y.. Value of PAX8 and WT1 immunostaining in confirming the ovarian origin of metastatic carcinoma in serous effusion specimens. Am J Clin Pathol 137:304-9, 2012. PMID: 22261458.
53. Hatzis C, Pusztai, L Valero V, Booser DJ, Esserman L, Lluch A, Vidaurre T, Holmes F, Souchon E, Martin M, Cotrina J, Gomez H, Hubbard R, Ferrer-Lozano J, Dyer R, Buxton M, Gong Y, Wu Y, Ibrahim N, Andreopoulou E, Ueno N, Hunt K, Yang W, Nazario A, DeMichele A, O'Shaughnessy J, Hortobagyi GN, and Symmans WF.. A genomic predictor of response and survival following taxane-anthracycline chemotherapy for invasive breast cancer. JAMA (Journal of the American Medical Association) 305:1873-881, 2011. PMID: 21558518.
54. Iwamoto T, Bianchini G, Qi Y, Cristofanilli M, Lucci A, Woodward WA, Reuben JM, Matsuoka J, Gong Y, Krishnamurthy S, Valero V, Hortobagyi GN, Robertson F, Symmans WF, Pusztai L, Ueno NT.. Different gene expressions are associated with the different molecular subtypes of inflammatory breast cancer. Breast Cancer Res Treat 125:785-95, 2011. PMID: 21153052.
55. Billah S, Stewart J, Staerkel G, Chen S, Gong Y, Guo M.. EGFR and KRAS mutations in lung carcinoma: Molecular testing by using cytology specimens. Cancer Cytopathol 119:111-17, 2011. PMID: 21400670.
56. Guo M, Warriage I, Mutyala B, Patel S, Lin E, Gong Y, Sneige N.. Evaluation of p16 immunostaining to predict high-grade cervical intraepithelial neoplasia in women with Pap results of atypical squamous cells of undetermined significance. Diagn Cytopathol 39:482-88, 2011. PMID: 20607682.
57. Han J, Baik N, Kim KH, Yang JM, Han GW, Gong Y, Jardi M, Castellino FJ, Felez J, Parmer RJ, Miles LA.. Monoclonal antibodies detect receptor-induced binding sites in glu-plasminogen. Blood 118:1653-62, 2011. PMCID: PMC3156051.
58. *Gong Y, Huo L, Liu P, Sneige N, Sun X, Ueno NT, Lucci A, Buchholz TA, Valero V, Cristofanilli M.. Polycomb group protein EZH2 is frequently expressed in inflammatory breast cancer and is predictive of worse clinical outcome. Cancer 117:5476-84, 2011. PMID: 21713757.
59. Ergin AB, Cristofanilli M, Daw H, Tahan G, Gong Y.. Recurrent granulomatous mastitis mimicking inflammatory breast cancer. BMJ Case Rep Jan 2011:bcr0720103156, 2011. PMCID: PMC3062046.
60. *Gong Y, Han EY, Guo M, Pusztai L, Sneige N.. Stability of estrogen receptor status in breast carcinoma: a comparison between primary and metastatic tumors with regard to disease course and intervening systemic therapy. Cancer 117:705-13, 2011. PMID: 20939012.
61. *Xiao C, Gong Y, Han EY, Gonzalez-Angulo AM, Sneige N.. Stability of HER2-positive status in breast carcinoma: a comparison between primary and paired metastatic tumors with regard to the possible impact of intervening trastuzumab treatment. Ann Oncol 22:1547-53, 2011. PMID: 21239403.
62. Xiao L, Wang Y, Gong Y, Guo C.. The TMPRSS2-ERG Gene Fusion in Metastatic Prostate Cancers: A Study of Fine Needle Aspiration Specimens. Zhonghua Bing Li Xue Za Zhi (In Chinese) 40:392-96, 2011. PMID: 21914348.
63. Li J, Gonzalez-Angulo AM, Allen PK, Yu TK, Woodward WA, Ueno NT, Lucci A, Krishnamurthy S, Gong Y, Bondy ML, Yang W, Willey JS, Cristofanilli M, Valero V, Buchholz TA.. Triple-Negative/Basal Subtype Predicts Poor Overall Survival and High Locoregional Relapse in Inflammatory Breast Cancer. Oncologist 16:1675-83, 2011. PMCID: PMC3248766.
64. Dawood S, Gong Y, Broglio K, Buchholz TA, Woodward W, Lucci A, Valero V, Gonzalez-Angulo AM, Hortobagyi GN, Cristofanilli M. Trastuzumab in primary inflammatory breast Cancer (IBC): high pathological response rates and improved outcome. Breast J e-pub, 7/2010. PMCID: PMC3097300.
65. Tabchy A, Valero V, Vidaurre T, Lluch A, Gomez H, Martin M, Qi Y, Barajas-Figueroa L, Souchon E, Coutant C, Doimi FD, Ibrahim NK, Gong Y, Hortobagyi GN, Hess K, Symmans WF, Pusztai L.. Evaluation of the performance of a 30-gene paclitaxel, 5-fluroruracil, doxorubicin and cyclophosphamide (T/FAC) chemotherapy response predictor in a randomized clinical trial in breast cancer. Clin Cancer Res 16:5351-61, 2010. PMID: 20829329.
66. Arias-Pulido H, Gong Y (co-first author), Joste N, Lomo L, Lee S, Verschraegen C, Lara J, Prossnitz E, Cristofanilli M, Royce M.. GPR30 and estrogen receptor expression: new insights into hormone dependence of inflammatory breast cancer. Breast Cancer Res Treat 123:51-8, 2010. PMCID: PMC2904403.
67. *Xiao C, Gong Y, Fu L.. Research and clinical management of inflammatory breast carcinoma: Current status and future direction. Chin J Breast Dis 4:22-5, 2010. PMID: 20193452.
68. Gu F, Ma Y, Fan Y, Lang R, Ding T, Hao X, Gong Y, Kobayashi H, Fang Z, Fu L.. Synovial sarcoma individual chemotherapy directed by collagen gel droplet embedded culture drug sensitivity test: A case report. Oncology Letters 1:885-88, 2010. PMCID: PMC3436474.
69. *Gong Y, Sweet W, Duh YJ, Greenfield L, Fang Y, Zhao J, Tarco E, Symmans WF, Isola J, Sneige N. Chromogenic in situ hybridization (CISH) is a reliable method for detecting HER2 gene status in breast cancer: a multicenter study using conventional scoring criteria and the new ASCO/CAP recommendations. Am J Clin Pathol 131:490-97, 2009. PMID: 19289584.
70. Pusztai L, Jeong J, Gong Y, Ross J, Kim C, Hortobagyi GN, Paik S, Symmans WF. Evaluation of Microtubule-Associated Protein-Tau Expression As a Prognostic and Predictive Marker in the NSABP-B 28 Randomized Clinical Trial. J Clin Oncol 27:4287-92, 2009. PMCID: PMC2744271.
71. Ge Y, Sneige N, Eltorky MA, Wang Z, Lin E, Gong Y, Guo M. Immunohistochemical characterization of subtypes of male breast carcinoma. Breast Cancer Res 14;11:R28, 2009. PMCID: PMC2716496.
72. *Payne M, Staerkel G, Gong Y. Indeterminate diagnosis in fine-needle aspiration of the pancreas: reasons and clinical implications. Diagn Cytopathol 37:21-9, 2009. PMID: 18973122.
73. *Gong Y, Sweet W, Duh YJ, Greenfield L, Tarco E, Trivedi S, Symmans WF, Isola J, Sneige N. Performance of chromogenic in situ hybridization on testing HER2 status in breast carcinomas with chromosome 17 polysomy and equivocal (2+) HercepTest: a study of two institutions using conventional and the new ASCO/CAP scoring criteria. Am J Clin Pathol 132:228-36, 2009. PMID: 19605817.
74. *Piao Y, Guo M, Gong Y. Diagnostic challenges of metastatic spindle cell melanoma on fine-needle aspiration specimens. Cancer 114:94-101, 2008. PMID: 18260089.
75. Guo M, Gong Y, Deavers M, Silva EG, Jan YJ, Cogdell DE, Luthra R, Lin E, Lai HC, Zhang W, Sneige N. Evaluation of a commercialized in situ hybridization assay for detecting human papillomavirus DNA in tissue specimens from patients with cervical intraepithelial neoplasia and cervical carcinoma. J Clin Microbiol 46:274-80, 2008. PMCID: PMC2224284.
76. *Angeles R, Gong Y,. Fine-needle aspiration of a subcutaneous gouty tophus. Diagn Cytopathol 36:494-95, 2008. PMID: 18528887.
77. Guo M, Lin CY, Gong Y, Cogdell DE, Zhang W, Lin E, Sneige N. Human papillomavirus genotyping for the eight oncogenic types can improve specificity of HPV testing in women with mildly abnormal pap results. Mod Pathol 21:1037-43, 2008. PMID: 18500260.
78. Uzquiano MC, Prieto VG, Nash JW, Ivan DS, Gong Y, Lazar AJ, Diwan AH. Metastatic basal cell carcinoma exhibits reduced actin expression. Mod Pathol 21:540-43, 2008. PMID: 18223552.
79. Dawood S, Broglio K, Gong Y, Yang WT, Cristofanilli M, Kau SW, Meric FB, Buchholz TA, Hortobagyi GN, Gonzalez-Angulo A. Prognostic significance of HER2 status in women with inflammatory breast cancer. Cancer 112:1905-11, 2008. PMID: 18300243.
80. Arun B, Logan C, Broglio K, Yin C, Valero V, Kuerer H, Meric-Bernstam F, Gong Y, Browne D, Hortobagyi GN, Sneige N. Comparison of ductal lavage and random periareolar fine-needle aspiration as tissue acquisition methods in early breast cancer prevention trials. Clin Cancer Res 13:4943-48, 2007. PMID: 17699874.
81. *Gong Y, Yan K, Lin F, Anderson K, Sotiriou C, Andre F, Holmes FA, Valero V, Booser D, Pippen JE, Vukelja S, Gomez H, Mejia J, Barajas LJ, Hess KR, Sneige N, Hortobagyi GN, Pusztai L, Symmans WF. Determination of estrogen-receptor status and ERBB2 status of breast carcinoma: a gene-expression profiling study. Lancet Oncol 8:203-11, (Press Release), 2007. PMID: 17329190.
82. Cabioglu N, Gong Y (co-first author), Islam R, Broglio KR, Sneige N, Sahin A, Gonzalez-Angulo AM, Morandi P, Bucana C, Hortobagyi GN, Cristofanilli M. Expression of growth factor and chemokine receptors: new insights in the biology of inflammatory breast cancer. Ann Oncol 18:1021-29, 2007. PMID: 17351259.
83. *Gong Y, Joseph T, Sneige N. Author reply to used immunostains on cell-transferred cytologic specimens. Cancer 108:135-36, 2006. PMID: 15852338.
84. Sneige N, Liu B, Yin G, Gong Y, Arun BK. Correlation of cytologic findings and chromosomal instability detected by fluorescence in situ hybridization in breast fine-needle aspiration specimens from women at high risk for breast cancer. Mod Pathol 19:622-29, 2006. PMID: 16528376.
85. Gonzalez-Angulo AM, Guarneri V, Gong Y, Cristofanilli M, Morales-Vasquez F, Sneige N, Hortobagyi G, Esteva FJ. Downregulation of the cyclin-dependent kinase inhibitor p27kip1 might correlate with poor disease-free and overall survival in inflammatory breast cancer. Clin Breast Cancer 7:326-30, 2006. PMID: 17092400.
86. *Alrahwan D, Staerkel G, Gong Y. Fine needle aspiration cytology of a metastatic duct carcinoma of the prostate: a case report. Acta Cytol 50:469-72, 2006. PMID: 16901017.
87. *Gong Y, Sun X. Fine-needle aspiration of a presacral myelolipoma. Diagn Cytopathol 34:29-30, 2006. PMID: 16355397.
88. *Ren R, Guo M, Sneige N, Moran CA, Gong Y. Fine-needle aspiration of adrenal cortical carcinoma: cytologic spectrum and diagnostic challenges. Am J Clin Pathol 126:389-98, 2006. PMID: 16880150.
89. *Huang P, Staerkel G, Sneige N, Gong Y. Fine-needle aspiration of pancreatic serous cystadenoma: cytologic features and diagnostic pitfalls. Cancer 108:239-49, 2006. PMID: 16691573.
90. *Gong Y, Caraway N, Stewart J, Staerkel G. Metastatic ductal adenocarcinoma of the prostate: cytologic features and clinical findings. Am J Clin Pathol 126:302-9, 2006. PMID: 16891207.
91. Anderson K, Hess KR, Kapoor M, Tirrell S, Courtemanche J, Wang B, Wu Y, Gong Y, Hortobagyi GN, Symmans WF, Pusztai L. Reproducibility of gene expression signature-based predictions in replicate experiments. Clin Cancer Res 12:1721-27, 2006. PMID: 16551855.
92. *Gong Y, Sneige N, Guo M, Hicks ME, Moran CA. Transthoracic fine-needle aspiration vs concurrent core needle biopsy in diagnosis of intrathoracic lesions: a retrospective comparison of diagnostic accuracy. Am J Clin Pathol 125:438-44, 2006. PMID: 16613349.
93. Gong Y, Booser DJ, Sneige N. Comparison of HER-2 status determined by fluorescence in situ hybridization in primary and metastatic breast carcinoma. Cancer 103:1763-69, 2005. PMID: 15786420.
94. *Gong Y, Sun X, Huo L, Wiley EL, Rao MS. Expression of cell adhesion molecules, CD44s and E-cadherin, and microvessel density in invasive micropapillary carcinoma of the breast. Histopathol 46:24-30, 2005. PMID: 15656882.
95. *Gong Y, Jalali M, Staerkel G. Fine needle aspiration cytology of a thyroid metastasis of metaplastic breast carcinoma: a case report. Acta Cytol 49:327-30, 2005. PMID: 15966298.
96. *Gong Y, Ren R, Ordonez NG, Sun X, Sneige N. Fine needle aspiration cytology of well-differentiated papillary mesothelioma: a case report. Acta Cytol 49:537-42, 2005. PMID: 16334033.
97. *Ren R, Sun X, Staerkel G, Sneige N, Gong Y. Fine-needle aspiration cytology of a liver metastasis of follicular dendritic cell sarcoma. Diagn Cytopathol 32:38-43, 2005. PMID: 15584048.
98. Gong Y, Krishnamurthy S. Fine-needle aspiration of an unusual case of poorly differentiated insular carcinoma of the thyroid. Diagn Cytopathol 32:103-7, 2005. PMID: 15637672.
99. Gong Y, Gilcrease M, Sneige N. Reliability of chromogenic in situ hybridization for detecting HER-2 gene status in breast cancer: comparison with fluorescence in situ hybridization and assessment of interobserver reproducibility. Mod Pathol 18:1015-21, 2005. PMID: 15861212.
100.*Gong Y, Joseph T, Sneige N. Validation of commonly used immunostains on cell-transferred cytologic specimens. Cancer 105:158-64, 2005. PMID: 15852338.
101.Kidwai N, Gong Y, Sun X, Deshpande CG, Yeldandi A, Rao MS, Badve S. Expression of androgen receptor and prostate-specific antigen in male breast carcinoma. Breast Cancer Res 6:R18-23, 2004. PMID: 14680496.
102.Gong Y, Symmans WF, Krishnamurthy S, Patel S, Sneige N. Optimal fixation conditions for immunocytochemical analysis of estrogen receptor in cytologic specimens of breast carcinoma. Cancer 102:34-40, 2004. PMID: 14968416.
103.Sun X, Peterson LC, Gong Y, Traynor AE, Nelson BP. Post-transplant plasma cell myeloma and polymorphic post-transplant lymphoproliferative disorder with monoclonal serum protein occurring in solid organ transplant recipients. Mod Pathol 17:389-94, 2004. PMID: 14976525.
104.Miles LA, Castellino FJ, Gong Y. Critical role for conversion of glu-plasminogen to lys-plasminogen for optimal stimulation of plasminogen activation on cell surfaces. Trends Cardiovasc Med 13:21-30, 2003. PMID: 12554097.
105.Zhang L, Gong Y, Grella DK, Castellino FJ, Miles LA. Endogenous plasmin converts glu-plasminogen to lys-plasminogen on the monocytoid cell surface. J Thromb Haemost 1:1264-70, 2003. PMID: 12871329.
106.Gong Y, Caraway N, Gu J, Zaidi T, Fernandez R, Sun X, Huh YO, Katz RL. Evaluation of interphase fluorescence in situ hybridization for the t(14;18)(q32;q21) translocation in the diagnosis of follicular lymphoma on fine-needle aspirates: a comparison with flow cytometry immunophenotyping. Cancer 99:385-93, 2003. PMID: 14681948.
107.Gong Y, Sun X, Michael CW, Attal S, Williamson BA, Bedrossian CW. Immunocytochemistry of serous effusion specimens: a comparison of ThinPrep vs cell block. Diagn Cytopathol 28:1-5, 2003. PMID: 12508174.
108.Sun X, Gong Y, Pins MR. Pathologic quiz case: a paratesticular mass in a 55-year-old man. Arch Pathol Lab Med 127:e111-12, 2003. PMID: 12562270.
109.Gong Y, DeFrias DVS, Nayar R. Pitfalls in fine needle aspiration cytology of extraadrenal paraganglioma. A report of 2 cases. Acta Cytol 47:1082-86, 2003. PMID: 14674085.
110.Gong Y, Sun X, Haines GK III, Pins MR. Renal cell carcinoma, chromophobe type, with collecting duct carcinoma and sarcomatoid components. Arch Pathol Lab Med 127:e38-40, 2003. PMID: 12562294.
111.Sun X, Gong Y, Talamonti MS, Rao MS. Expression of cell adhesion molecules, CD44s and E-cadherin, and microvessel density in carcinoid tumors. Mod Pathol 15:1333-38, 2002. PMID: 12481015.
112.Sun X, Gong Y, Rao MS, Badve S. Loss of BRCA1 expression in sporadic male breast carcinoma. Breast Cancer Res Treat 71:1-7, 2002. PMID: 11859870.
113.Gong Y, Chao J, Bauer B, Sun X, Chou PM. Primary cutaneous alveolar rhabdomyosarcoma of perineum. Arch Pathol Lab Med 126:982-84, 2002. PMID: 12171502.
114.Gong Y, Kim SO, Grella DK, Castellino FJ, Miles LA. Conversion of glu-plasminogen to lys-plasminogen is necessary for optimal stimulation of plasminogen activation on the endothelial cell surface. J Biol Chem 276:19078-83, 2001. PMID: 11264290.
115.Parmer RJ, Mahata M, Gong Y, Mahata SK, Jiang Q, O'Connor DT, Xi XP, Miles LA,. Processing of chromogranin A by plasmin provides a novel mechanism for regulating catecholamine secretion. J Clin Invest 106:907-15, 2000. PMID: 11018079.
116.Parmer RJ, Mahata SK, Jiang Q, Taupenot L, Gong Y, Mahata M, O'Connor DT, Miles LA,. Tissue plasminogen activator and chromaffin cell function. Adv Exp Med Biol 482:179-92, 2000. PMID: 11192579.
117.Gong Y, Xu Y. Effects of cadmium on macrophage-mediated cytotoxicity toward tumor cells. Zhejiang Medical Journal (In Chinese) 13:3-6, 1991.
118.Gong Y. Effects of cadmium on macrophage. J. Environ Health (In Chinese) 6:42-45, 1989.
Invited Articles
1. *Gong Y. Commentary on “Lack of CD151/integrin a3b1 complex is predictive of poor outcome in node-negative lobular breast carcinoma: opposing roles of CD151 in invasive lobular and ductal breast cancers”. Breast Disease: A Year Book Quarterly 27(2), 2016.
2. *Gong Y. Commentary on “Histologic Grade Remains a Prognostic Factor for Breast Cancer Regardless of the Number of Positive Lymph Nodes and Tumor Size--A Study of 161 708 Cases of Breast Cancer From the SEER Program”. Breast Disease: A Year Book Quarterly 26(1), 2015.
3. *Gong Y. Commentary on "High TFAP2C/low CD44 expression is associated with an increased rate of pathologic complete response following neoadjuvant chemotherapy in breast cancer". Breast Diseases: A Year Book Quarterly 25(2), 2014.
4. *Gong Y. Commentary on "Accurate and rapid novel genetic diagnosis for detection of sentinel lymph node metastasis in breast cancer patient". Breast Diseases: A Year Book Quarterly 24(1), 2013.
5. *Zheng J, Gong Y. Fine needle aspiration of pancreatic lesions: diagnostic features and pitfalls. Chin J Dig Endosc 30:421-23, 2013.
6. Zhang S and Gong Y. From Cytomorphology to Molecular Pathology: Maximizing the Value of Cytology of Lymphoproliferative Disorders and Soft Tissue Tumors. Am J Clin Pathol 140:454-67, 2013. PMID: 24045541.
7. *Gong Y.. Significance of biomarker discordance in breast cancer from the pathologist's perspective. Cancer Biomarkers 12:207-18, 2013. PMID: 23735941.
8. *Gong Y. Commentary on "Assessment of Ki67 in Breast Cancer: Recommendations from the International Ki67 in Breast Cancer Working Group". Breast Diseases: A Year Book Quarterly 23(3), 2012.
9. *Gong Y. Commentary on "In situ immune response after neoadjuvant chemotherapy for breast cancer predicts survival". Breast Diseases: A Year Book Quarterly 23(4), 2012.
10. *Gong Y. Commentary on "Intrinsic breast tumor subtypes, race, and long-term survival in the Carolina breast cancer study". Breast Diseases: A Year Book Quarterly 22(3), 2011.
11. *Kundu U, Gong Y. Malignant Mixed Mullerian Tumor with a Lung Metastasis: Fine Needle Aspiration Cytology and Histology Correlation. Pathology Case Reviews 16:90-93, 2011.
12. *Cheng Y, Gong Y. Diagnostic pitfalls of an inguinal endometriosis sampled via fine-needle aspiration. Cytopathol 37:113-23, 2009.
13. *Gong Y, Xiao C, Fu L. HER2 testing: Current issues and future directions. Chin J Pathol 38:795-99, 2009.
14. *Gong Y. Pathology aspect of inflammatory breast cancer: part 2. Biologic insights into its aggressive phenotype. Semin Oncol 35:33-40, 2008. PMID: 18308144.
15. *Gong Y, Symmans WF, Pusztai L. Gene expression microarrays provide new prognostic and predictive tests for breast cancer. Pharmacogenomics 8:1359-68, 2007. PMID: 17979510.
Book Chapters
1. *Gong Y. Molecular study of breast cancer in cytology samples. In: Molecular Cytopathology. Ed(s) B. Yang, J. Rao. Springer: New York, 2016.
2. Chen YH, Gong Y. Cytopathology in the diagnosis of lymphoma. In: Cytology in Oncology, 160. Ed(s) R. Nayar. Springer: New York, 211-240, 2014. PMCID: PMC24092372.
3. Zhang X, Huang Y, Gong Y. Fine-needle aspiration of liver lesions. In: Fine Needle Aspiration Cytopathology (In Chinese). Ed(s) Zhao C, Pantanowitz L, Yang M. Beijing Scientific Publisher: Beijing, 216-46, 2014.
4. *Gong Y. Ancillary studies on Neoplastic Cytologic Specimens. In: Cytology in Oncology. Ed(s) R. Nayar. Springer: New York, 13-29, 2013.
5. *Gong Y. Breast Cancer: Pathology, Cytology and Core Needle Biopsy methods for diagnosis (Chapter 2). In: Breast and Gynecological Cancers: An Integrated Approach for Screening and Early Diagnosis in Developing Countries. Ed(s) Mahesh K. Shetty. Springer: New York, 19-37, 2013.
6. Miles LA, Andronicos NM, Felez J, Grella DK, Castellino FJ, Gong Y. The role of Lys-plasminogen in cell-mediated plasmin production. In: Plasminogen: Structure, Activation and Regulation. Ed(s) :DM Waisman. Kluwer Academic/Plenum Publishers, New York, pp 1-17, 2003.
Books (edited and written)
1. *Gong Y. Ed(s) Y. Gong. Metastatic Neoplasms in Fine-Needle Aspiration Cytology: Diagnostic Tips and Traps. Springer: New York, 2016.
Letters to the Editor
1. *Wang J, Gong Y.. Metastatic Papillary Thyroid Carcinoma in the Thigh with Unusual Cytologic Features. Diagn Cytopathol 42:278-79, 2014. PMID: 23007921.
2. *Zhao XR, Gong Y.. Fine needle aspiration diagnosis of an early onset post-transplant lymphoproliferative disorder. Diagn Cytopathol 39:788-90, 2011. PMID: 21919218.
3. *Angeles R, Gong Y. Fine-needle aspiration cytology of a rheumatoid arthritis-associated interstitial lung disease. Diagn Cytopathol 36:686-88, 2008. PMID: 18677753.
4. *Angeles R, Gong Y.. Seminal vesicle epithelium: a source of diagnostic dilemma in fine-needle aspiration specimen. Diagn Cytopathol 36:923-24, 2008. PMID: 18855908.
5. *Ren R, Gong Y. Fine-needle aspiration of a parathyroid hyperplasia with unusual clinical and cytologic presentation. Diagn Cytopathol 35:250-51, 2007. PMID: 17351936.
