⑴ The development of new compounds which inhibit the acute rejection using rat heart transplant model. (Active Biotech AB,Lund,Sweden2001-2004） 經費150,000美元
⑵ Tutor for the international course of microsurgery,and scientific adviser (DiLab,Lund,Sweden 2003-2006） 經費30,000美元
⑶ Initial inhibition of tissue factor signalling reduces chronic vascular changes in isogenic rat aortic transplants. (Novo Nordisk,Denmark 2003-2006） 經費60,000美元
回國後，主持的課題主要有：
⑴ 活體腎臟移植的系列研究
（廈門大學科研啟動經費 2007-2011）經費300萬人民幣
⑵ 胰島細胞和腎臟移植治療糖尿病腎病的研究
（福建省衛生科技聯合攻關項目 2008-2011）經費30萬人民幣
⑶ 抗CD40-L和抗LFA-1單抗在預防異種胰島移植排斥中的作用
（廈門市科技項目 2009-2011）經費10萬人民幣
⑷ 板藍根組酸單體抗腫瘤及抗器官移植排斥雙重作用的研究
（福建省科技重點項目2010-2013）經費15萬人民幣
專利情況
高級脂肪酸衍生物類新化合物及其製備方法和抗腫瘤用途
專利公開號：CN101475506A
專著情況
《活體供腎腎臟移植臨床規範》
作者：齊忠權 Henrik Ekberg（瑞典）
Wolters Kluwer Health Co.Ltd 於2009年12月出版
論著情況
Junjie Xia,1 Jibing Chen,2 Wei Shao,1 Tianshu Lan,1 Yongzhi Wang,1 Baiyi Xie,1 Henrik Thorlacius,3 Feng Tian,2 Ruxin Huang,4 Zhongquan Qi,Suppressing memory T cell activation induces islet allograft tolerance in alloantigen-primed mice. Transplant International. (*通訊作者）（accepted 2010）Feng Wang,JibingChen,WeiShao,Baiyi Xie,YongzhiWang,TianshuLan,HenrikThorlacius,Zhongquan Qi. Anti-CD44 Monoclonal Antibody Inhibits Heart Transplant Rejection Mediated by Alloantigen-primed CD4+Tm in Nude Mice. Transplant Immunology. (*通訊作者）（accepted 2010）Lan Tianshu,Chen Jibing,Kang Xiangpeng,Wang Feng,Wang Yongzhi,Xia Junjie,Qi Zhongquan. Pre-contact of tolerance circumstance protect the allograft from attacking by memory T cells. Scandinavian Journal of Immunology(*通訊作者）（accepted 2010）Xiangpeng Kang,Jibing Chen,Qing Qin,Feng Wang,Yongzhi Wang,Tianshu Lan,Shuo Xu,Feiyu Wang,Junjie Xia,Henrik Ekberg,Zhongquan Qi,Zhongchen Liu.Isatis tinctoria L. combined with co-stimulatory molecules blockade prolongs survival of cardiac allografts in alloantigen-primed mice. Transpl Immunol. (*通訊作者）（accepted 2010）Baiyi Xie,Jibing Chen,Feng Wang,Tianshu Lan,Yongzhi Wang,Junjie Xia,Zhi Li,Qingxiang Xie,Ruxin Huang,Zhongquan Qi. Monoclonal Antibody Treatment to Prolong the Secondary Cardiac Allograft Survival in Alloantigen-primed Mice. Scandinavian Journal of Immunology. (*通訊作者）（accepted 2010）Liang H,Liao C,Qi Z,Sha C,Xie B,Chen J,Xia J,Wang Y,Yao Q,Zhao Y. Rapamycin or tacrolimus alone fails to resist cardiac allograft accelerated rejection mediated by alloreactive CD4(+) memory T cells in mice. Transpl Immunol. 2009; [Epub ahead of print]Hua Liang,Yongxiang Zhao,Zhonggui San,Chongxian Liao,Chuang Sha,Baiyi Xie,Jibing Chen,Junjie Xia,Yongzhi Wang,Zhongquan Qi（通訊作者）. The recall alloresponse following retransplantation is more intense compared with the T cell memory-transfer model.Immunol Invest,2010 (accepted,manuscript ID: LIMM-2009-0045）Zhao Y,Zhang S,Zhou J,Wang J,Zhen M,Liu Y,Chen J,Qi Z*. The Development of a Tissue-Engineered Artery Using Decellularized Scaffold and Autologous Ovine Mesenchymal Stem Cells. Biomaterials 2009 Oct ; 31:296–307.(IF=6.6） (*通訊作者）Chen X,Shao W,Chen J,Zhang L,Corbascio M,Shi-Guang S and Qi Z*. Allotransplantation of Sulphate Glucomannan-Alginate Barium (SGA) –Microencapsulated Rat Islets for the Treatment of Diabetes Mellitus. Immunological investigation 2009 July; 38:1-11. (*通訊作者）Xie B,Chen J,Xia J,Wang Y,Liang H,Henrik E,Matthias C and Qi Z*. Combined Costimulation Blockade Inhibits Accelerated Rejection Mediated by Alloantigen-Primed Memory T cells in Mice. Immunological investigation 2009 Oct;38:1-13. (*通訊作者）Wang Y,Chen J,Qin Q,Kuang X,Xia J,Xie B,Wang F and Qi Z*. Synergistic Effects of Isatidis and Tacrolimus in the Prevention of Acute Heart Rejection in Mice. Transplantation immunology 2009 Sep;22:5-11. (*通訊作者）Eriksson T,Wallin R,Hoglund P,Roth B,Qi Z,Ostraat O,Bjorkman S. Low bioavailability of rectally administered thalidomide. Am J Health Syst Pharm.2000 ; 57⒄： 1607-10.Oderup C,Malm H,Ekberg H,Qi Z,Veress B,Ivars F,Corbascio M. Costimulation blockade-induced cardiac allograft tolerance: inhibition of T cell expansion and accumulation of intragraft cD4(+)Foxp3(+) T cells. Transplantation. 2006 15; 82⑾： 1493-500.Zhang L,Qi Z,Shan S,Wu D,Sun Y,Ekberg H. The effects of leflunomide and FK 506 on rejection of xenografts in rat-to-mouse. Scand J Immunol. 2004; 59⑶： 255-60.Zaina S,Pettersson L,Thomsen AB,Chai CM,Qi Z,Thyberg J,Nilsson J. Shortened life span,bradycardia,and hypotension in mice with targeted expression of an Igf2 transgene in smooth muscle cells. Endocrinology 2003 ; 144⑹： 2695-703. Corbascio M,Mahanty H,Osterholm C,Qi Z,Pearson TC,Larsen CP,Freise CE,Ekberg H. Anti-lymphocyte function-associated antigen-1 monoclonal antibody inhibits CD40 ligand-independent immune responses and prevents chronic vasculopathy in CD40 ligand-deficient mice. Transplantation 2002 ;74⑴：35-41.Corbascio M,Ekstrand H,Osterholm C,Qi Z,Simanaitis M,Larsen CP,Pearson TC,Riesbeck K,Ekberg H. CTLA4Ig combined with anti-LFA-1 prolongs cardiac allograft survival indefinitely. Transpl Immunol. 2002 ; 10⑴： 55-61.Österholm C,Qi Z,Ekberg J,Veress B,Pyke C,Hedner U,Ekberg H. Initial inhibition of tissue factor signalling reduces chronic vascular changes in isogenic rat aortic transplants. Am J Transplantation 2001 ; 1⑴： 29-37.Eriksson T,Wallin R,Hoglund P,Roth B,Qi Z,Ostraat O,Bjorkman S. Low bioavailability of rectally administered thalidomide. Am J Health Syst Pharm.2000 ; 57⒄： 1607-10.M Olausson,D Lukes,J Norrby,Qi Z,Ekberg H,Gannedahl G,Tufvesson G,Mjörnstedt L. Antithymocyte Globulin and Cyclosporine A are Synergistic in an Experimental Transplantation Tolerance Model in the Rat. Scand J Immunol .1999; 49⑴： 38-44.Qi Z,Tufveson G,Ekberg H. Tolerance or rejection : A delicate balance as judged by exposure of heart-transplanted rats to the immunomodulator Linomide. Scand J Immunol. 1999; 50⑷： 394-8.Qi Z,Simanaitis M,Ekberg H. Malononitrilamides and tacrolimus additively prevent acute rejection in rat cardiac allografts.Transpl Immunol. 1999; 7⑶： 169-75.Östraat Ö,Qi Z,Tufveson G,Hedlund G,Ekberg H. The effects of leflunomide and cyclosporin A on rejection of cardiac allograft in rat. Scand.J.Immuno. 1998; 48⑷： 379-88.Petersson E,Qi Z,Hedlund G,Ekberg H. Activation of donor-specific CTL in a tolerant recipient of cardiac allograft. Cell Immunol. 1998; 189⑴：19-24.Qi Z,Ekberg H. Malononitrilamides prevent and suppress allospecific antibody production. Transplant Proc. 1998 ; 30⑻： 3980. Qi Z,Ekberg H. Malononitrilamides 715 and 279 prolong rat cardiac allograft survival,reverse ongoing rejection,inhibit allospecific antibody production and interact positively with cyclosporin. Scand J Immunol. 1998; 48⑷： 379-88.Qi Z,Simanaitis M,Ekberg H. Malononitrilamides 715 and 279 prevent accelerated cardiac allograft rejection synergistically with cyclosporin A in presensitized rats. Transpl Immunol. 1998; 6⑵： 94-100.Östraat Ö,Qi Z,Olausson M,Tufveson G,Ekberg H. Mycophenolate mofetil,azathioprine and cyclophosphamide enhanced efficacy combined with cyclosporine in rat cardiac transplantation. Scand J Immunol. 1997; 45⑷： 343-8.Petersson E,Qi Z,Ekberg H,Ostraat O,Dohlsten M,Hedlund G. Activation of alloreactive natural killer cells is resistant to cyclosporine. Transplantation 1997 27; 63⑻： 1138-44.Qi Z,Riesbeck K,Östraat Ö,Tufvesson G,Ekberg H. Single dose anti-CD4 monoclonal antibody therapy for induction of tolerance to cardiac allografts in high- and low-responder rat strains. Transpl Immunol. 1997; 5⑶： 204-11.. Bjorkman S,Fyge A,Qi Z. Determination of the steady state tissue distribution of midazolam in the rat. J Pharm Sci. 1996; 85⑻： 887-9.Östraat Ö,Riesbeck K,Qi Z,Eriksson T,Schatz H,Ekberg H. Thalidomide prolonged graft survival in a rat cardiac transplant model but had no inhibitory effect on lymphocyte function in vitro. Transpl Immunol. 1996 ; 4⑵： 117-25.33. Bojrup M,Qi Z,Bjorkman S,et al. Bioavailability of cyclosporine in rats after intragastric administration: a comparative study of the L2-phase and two other lipid-based vehicles. Transpl Immunol. 1996; 4⑷： 313-7
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