須志平

須志平，女，博士，華東理工大學藥學院副教授。

基本介紹

• 中文名：須志平
• 畢業院校：南京農業大學
• 學位/學歷：博士
• 職業：教師
• 專業方向：建立多個靶標昆蟲的活體和離體篩選模型
• 任職院校：華東理工大學

個人經歷

1998.09-2002.06農學學士 南京農業大學 植物保護系

2002.09-2008.06理學博士 南京農業大學 植物保護學院 農藥系

2008.07-至今 華東理工大學 藥學院 藥物化工研究所

2015.09-2016.10訪問學者 美國Kansas State University昆蟲系

研究方向

ø農藥的生物評價及生理毒理研究：

1.針對綠色化學農藥的創製需求，建立多個靶標昆蟲的活體和離體篩選模型，進行生物活性評價和作用機制研究；

2.藉助細胞技術，利用昆蟲細胞系和急性解離昆蟲神經細胞，對新殺蟲化合物和重要殺蟲劑品種進行細胞毒理學研究；

ø殺蟲劑毒理學和害蟲抗藥性研究：

1.構建煙粉虱（CYP6CM1）和果蠅（CYP6G1）的細胞色素P450s體外表達系統，用於新型殺蟲化合物和重要殺蟲劑品種的代謝機理和互動抗性研究；

學術成果

目前在領域內相關學術期刊參與發表22篇SCI學術論文，其中以第一作者或通訊作者發表學術論文10篇。主持國家自然科學基金青年基金1項 （31501674），完成中央高校基本科研業務費專項基金和上海市優秀青年教師基金各1項，參與多項國家級研究項目。參與申請發明中國專利8項，PCT專利3項，中國專利授權3項，美國授權專利1項，加拿大授權專利1項。

發表部分論文：

[1]Zhiping Xu,Miaoqing Lu, Mingjun Yang, Wenping Xu, Jufang Gao, Yang Zhang,Yun Yang, Liming Tao. Pyrethrum-extract induced autophagy in insect cells: A new target?Pestic Biochem Physiol.2017

[2]吳勇超,須志平*,邵旭升,程家高*,李忠.環氧蟲啶對苜蓿蚜的毒力及對其體內解毒酶活性的影響[J].農藥學學報2016

[3] Ziqian Zhang, Jiayao Wu, Zhihao Shang, Chao Wang, Jiagao Cheng,Xuhong Qian, Yi Xiao,*Zhiping Xu,*and Youjun Yang*. Photocalibrated NO Release from NNitrosated Napthalimides upon One-Photon or Two-Photon Irradiation.Anal. Chem.,2016,

[4]Zhiping Xu, Lina Shi, Danping Jiang, Jiagao Cheng, Xusheng Shao*, Zhong Li. Azobenzene Modified Imidacloprid Derivatives as Photoswitchable Insecticides: Steering Molecular Activity in a Controllable Manner.Scientific Reports,2015,

[5] Baoyan Zhang,Zhiping Xu*, Yixi Zhang, Xusheng Shao, Xiaoyong Xu, Jiagao Cheng, Li Zhong. Fipronil induces apoptosis through caspase-dependent mitochondrial pathways inDrosophilaS2 cells.Pestic Biochem Physiol.2015

[6] Xin Fang, Ying Tong Di, Yu Zhang,Zhi Ping Xu, Yang Lu, Qian Qian Chen, Qi Tai Zheng, and Xiao Jiang Hao*. Unprecedented Quassinoids with Promising Biological Activity fromHarrisonia perforate.Angew. Chem. Int. Ed.2015,

[7] Ziqian Zhang, Baoyan Zhang, Xuhong Qian, Zhong Li,Zhiping Xu*, Youjun Yang*. Simultaneous Quantification of Hgand MeHgin Aqueous Media with a Single Fluorescent Probe by Multiplexing in the Time Domain.Anal. Chem.,2014,

[8] Linlin Song, Zuhai Lei, Baoyan Zhang,Zhiping Xu*,Zhong Li*and Youjun Yang*. A Zero-Background Fluorescent Probe for HgDesigned via the “Covalent-Assembly” Principle.Anal. Methods,2014,

[9] Siyuan Lu, Xusheng Shao, Zhong Li,Zhiping Xu*, Shishuai Zhao, Yinli Wu, and Xiaoyong Xu*. Design, Synthesis and Particular Biological Behaviors of Chain-opening Nitromethylene Neonicotinoids withcis-Configuration.J. Agric. Food Chem.2012,

[10] Fengyi Liu,Zhiping Xu, Yu Cheng Zhu, Fangneng Huang, Yanhua Wang, Huiling Li, Hua Li, Congfen Gao, Weijun Zhou and Jinliang Shen*. Evidence of field-evolved resistance to Cry1Ac-expressingBtcotton inHelicoverpa armigera(Lepidoptera: Noctuidae) in northern China.Pest Management Science,2010,

[11]Zhiping Xu,Fengyi Liu, Jin Chen，Fangneng Huang, David A Andow, Yanhua Wang, Yu Cheng Zhu and Jinliang Shen* . Using F₂screen to monitor frequency of resistance alleles to Bt cotton in field populations ofHelicoverpa armigera(Hübner) (Lepidoptera: Noctuidae).PestManagement Science,2009,

[12] Fengyi Liu,Zhiping Xu, Juhua Chang, Jin Chen, Fenxia Meng,Yu Cheng Zhu, Jinliang Shen*. Resistance allele frequency to Bt cotton in field populations ofHelicoverpa armigera(Hübner) (Lepidoptera: Noctuidae) in China.Journal of Economic Entomology,2008,

[13] Wang Yanhua, Gao Congfen,Xu Zhiping,Zhu Yu Chen, Lin Youwei, Dai Dejiang, Zhou Weijun, Shen Jinliang*. Buprofezin susceptibility survey, resistance selection and preliminary determination of resistance mechanism inNilaparvata lugens(Homopetra: Delphacidae).PestManagement Science,2008,

[14]Yu Cheng Zhu, Fengyi Liu,Zhiping Xu,Juhua Chang, Jinliang Shen. F₁Screening for Resistance Gene Alleles to Bt Cotton inHelicoverpa armigera: How to Differentiate S and R Genotypes.J. Entomol. Sci.2008.