人物經歷
教育經歷
2016/09-2021/06:蘇州大學,功能納米與軟物質研究院,材料科學與工程,碩博連讀
2012/09-2016/06:浙江理工大學,啟新學院,材料科學與工程,本科
工作經歷
2024/07-至今:蘇州大學,功能納米與軟物質研究院,副教授
2021/07-2024/06:蘇州大學,功能納米與軟物質研究院,博士後
研究方向
1、生物活性納米材料的設計製備及腫瘤診療一體化研究
個人榮譽
1、入選蘇州大學“優秀青年學者”(2024)
2、入選江蘇省卓越博士後計畫(2022)
主持項目
1、國家自然科學基金委員會,青年基金項目(主持)
2、中國博士後科學基金會,第3批特別資助(主持)
3、中國博士後科學基金會,第70批面上資助(主持)
研究領域
1、生物活性納米材料的設計製備及腫瘤診療一體化研究
2、活性材料調控腫瘤免疫微環境放大免疫治療等研究
3、活性微球的設計構建及肝癌介入栓塞治療等研究
代表性研究成果
主要研究方向是探索設計構建一系列多功能生物活性納米材料用於調控腫瘤微環境增效腫瘤治療,具有豐富的材料合成、表征和生物套用的能力和經驗,在增效腫瘤氣體治療、聲動力治療、光熱治療、化動力治療及免疫治療等方面開展了一系列較為系統的工作,取得了具有一定國際影響力的研究成果,至今以第一作者/通訊作者共發表學術論文19篇,其中IF>10的論文15篇,其中包括Nat. Commun.、Chem、Angew. Chem. Int. Ed.、Adv. Mater.、ACS Nano、Nano Today、Nano Lett.、Adv. Funct. Mater.、Chem. Eng. J.等工材領域知名期刊。
代表性論文
1. Chen L, Cheng S, Lu S, Gao X, Gong F*, Shi J, Han Z, Wang Y, Yang X, Zhou X*, Cheng L*. Bioactive calcium hydride-driving “triple” hydrogen/alkaline/calcium therapy for efficient treatment of osteomyelitis. Small, 2024, 2306315.
2. Wang Y, Gong F*, Han Z, Lei H, Zou Y, Cheng S, Yang X, Wang T, Wang L, Yang N, Liu Z, Cheng L*. Oxygen-deficient molybdenum oxide nanosensitizers for ultrasound-enhanced cancer metalloimmunotherapy. Angew. Chem. Int. Ed., 2023, 135, e202215467.
3. Wei K, Gong F*, Wu J, Tang W, Liao F, Han Z, Pei Z, Lei H, Wang L, Shao M, Liu Z, Cheng L*. Orally administered silicon hydrogen nanomaterials as target therapy to treat intestinal diseases. ACS Nano, 2023, 17, 21539-21552.
4. Gong F, Xu J, Liu B, Yang N, Cheng L*, Huang P, Wang C, Chen Q, Ni C*, Liu Z*. Nanoscale CaH2 materials for synergistic hydrogen-immune cancer therapy. Chem, 2022, 8, 268-286.
5. Hou L, Gong F*, Han Z, Wang Y, Yang Y, Cheng S, Yang N, Liu Z, Cheng L*. HXV2O5 nanocatalysts combined with ultrasound for triple amplification of oxidative stress to enhance cancer catalytic therapy. Angew. Chem. Int. Ed., 2022, 61, e202208849.
6. Gong F, Yang N, Xu J, Yang X, Wei K, Hou L, Liu B, Zhao H, Liu Z, Cheng L*. Calcium hydride-based dressing to promote wound healing. Adv. Healthcare Mater., 2022, 12, 2201771.
7. Zhou Z, Gong F*, Zhang P, Wang X, Zhang R, Xia W, Gao X, Zhou X*, Cheng L*. Natural product curcumin-based coordination nanoparticles for treating osteoarthritis via targeting Nrf2 and blocking NLRP3 inflammasome. Nano Res., 2022, 15, 3338-3345.
8. Hou L, Gong F*, Liu B, Yang X, Chen L, Li G, Gong Y, Liang C, Yang N, Shen X, Liu Z, Cheng L*. Orally administered titanium carbide nanosheets as anti-inflammatory therapy for colitis. Theranostics, 2022, 12, 3834-3846.
9. Gong F, Cheng L*, Yang N, Gong Y, Ni Y, Bai S, Wang X, Chen M, Chen Q, Liu Z*. Preparation of TiH1.924 nanodots by liquid-phase exfoliation for enhanced sonodynamic cancer therapy. Nat. Commun., 2020, 11, 3712.
10. Gong F, Chen M, Yang N, Dong Z, Tian L, Hao Y, Zhuo M, Liu Z, Chen Q*, Cheng L*. Bimetallic oxide FeWOX nanosheets as multifunctional cascade bioreactors for tumor microenvironment-modulation and enhanced multimodal cancer therapy Adv. Funct. Mater., 2020, 30, 2002753.
11. Gong F, Yang N, Wang Y, Zhuo M, Zhao Q*, Wang S, Li Y, Liu Z, Chen Q, Cheng L*. Oxygen-deficient bimetallic oxide FeWOX nanosheets as peroxidase-like nanozyme for sensing cancer via photoacoustic imaging Small, 2020, 16, 2003496.
12. Gong F, Yang N, Wang X, Zhao Q, Chen Q, Liu Z, Cheng L*. Tumor microenvironment-responsive intelligent nanoplatforms for cancer theranostics Nano Today, 2020, 32, 100851.
13. Gong F, Cheng L*, Yang N, Betzer O, Feng L, Zhou Q, Li Y, Chen R, Popovtzer R, Liu Z*. Ultrasmall oxygen-deficient bimetallic oxide MnWOX nanoparticles for depletion of endogenous GSH and enhanced sonodynamic cancer therapy. Adv. Mater., 2019, 31, 1900730.
14. Gong F, Cheng L*, Yang N, Jin Q, Tian L, Wang M, Li Y, Liu Z*. Bimetallic oxide MnMoOX nanorods for in vivo photoacoustic imaging of GSH and tumor-specific photothermal therapy Nano Lett., 2018, 18, 6037-6044.
15. Gong F, Chen J, Han X, Zhao J, Wang M, Feng L, Li Y, Liu Z, Cheng L*. Core-shell TaOx@MnO2 nanoparticles as a nano-radiosensitizer for effective cancer radiotherapy J. Mater. Chem. B, 2018, 6, 2250-2257.
16. Gong F, Luo L, Yao Y*, Dai D, Lu W, Chen W. Drastic rate acceleration driven by synergistic effects: key role of persistent free radicals coupled with ascorbic acid in decomposition of organic contaminants by ferric citrate Chem. Eng. J., 2016, 304, 440-447.
17. Gong F, Wang L, Li D, Zhou F, Yao Y*, Lu W, Huang S, Chen W. An effective heterogeneous iron-based catalyst to activate peroxymonosulfate for organic contaminants removal Chem. Eng. J., 2015, 267, 102-110.