基本介紹
- 中文名：陶美鳳
- 國籍：中國
- 畢業院校：武漢大學
- 職稱：研究員
研究方向,發表論文,
研究方向
1. 放線菌分化和次生代謝調控機理的比較功能基因組研究；
2. 海洋微生物藥物挖掘的新策略和新技術；
3. 微生物次生代謝途徑解析及途徑工程；
4. 抗生素生物合成中的獨特酶促反應及其反應機理；
5. 抗生素高產育種的新技術理論體系，及其在重要抗生素菌種高產最佳化的套用。
發表論文
近年發表論文( * 責任作者)：
1. Xu H, Chater KF, Deng Z, Tao M*. (2008) A cellulose synthase-like protein involved in hyphal tip growth and morphological differentiation in Streptomyces. J Bacteriol. 190(14):4971-4978.
2. Wang L, Yu Y, He X, Zhou X, Deng Z, Chater KF, Tao M*. (2007) Role of an FtsK-like protein in genetic stability in Streptomyces coelicolor A3(2). J Bacteriol. 189(6):2310-2318.
3. Li W, Ying X, Guo Y, Yu Z, Zhou X, Deng Z, Kieser H, Chater KF, Tao M*. (2006) Identification of a gene negatively affecting antibiotic production and morphological differentiation in Streptomyces coelicolor A3(2). J Bacteriol. 188(24):8368-8375.
4. Li W, Wu J, Tao W, Zhao C, Wang Y, He X, Chandra G, Zhou X, Deng Z, Chater KF, Tao M*. (2007) A genetic and bioinformatic analysis of Streptomyces coelicolor genes containing TTA codons, possible targets for regulation by a developmentally significant tRNA. FEMS Microbiol Lett. 266(1):20-28.
5. Li W, Zhou H, Tao M*. (2007) Sequences downstream of the start codon and their relations to G + C content and optimal growth temperature in prokaryotic genomes. Antonie van Leeuwenhoek 92(4): 417-427.
6. Wang L, Tao M, Wendt-Pienkowski E, Galm U, Coughlin JM, Shen B*. (2009) Functional characterization of tlmK unveiling unstable carbinolamide intermediates in the tallysomycin biosynthetic pathway. J Biol Chem. 284(13):8256-8264. (共同第一作者)
7. Tao M, Wang L, Wendt-Pienkowski E, George NP, Galm U, Zhang G, Coughlin JM, Shen B*. (2007) The tallysomycin biosynthetic gene cluster from Streptoalloteichus hindustanus E465-94 ATCC 31158 unveiling new insights into the biosynthesis of the bleomycin family of antitumor antibiotics. Mol Biosyst. 3(1):60-74。
