藺宗是 浙江清華長三角研究院浙江省套用酶學重點實驗室課題組長。
基本介紹
- 中文名：藺宗
- 外文名：LinZong
- 國籍：中國
- 職業：博士 研究員
簡介,論文,
簡介
藺宗
博士 研究員
主要學習工作經歷：
1992-1996 南開大學生命科學院 本科
1996-2001 中科院生物物理所 博士
2001-2004 美國普林斯頓大學 博士後研究助理
2004-2011 美國普林斯頓大學 研究職員/副研究學者
2011-今
1996-2001 中科院生物物理所 博士
2001-2004 美國普林斯頓大學 博士後研究助理
2004-2011 美國普林斯頓大學 研究職員/副研究學者
2011-今
主要研究領域與方向：
使用生物化學和生物物理方法對蛋白質大分子進行結構和功能的研究，主要研究領域是蛋白質摺疊、聚合和分子伴侶的作用機制。
論文
1. N. W. Karuri, Z. Lin, H. S. Rye, J. E. Schwarzbauer, Probing the conformation of the fibronectin III1-2 domain by fluorescence resonance energy transfer, J.Biol.Chem. 284(6):3445-3452, 2009.
2. Z. Lin, D. Madan and H. S. Rye, GroEL stimulates protein folding through forced unfolding Nat. Struct. Mol. Biol. 15(3):303-311, 2008.
3. D. Madan, Z. Lin and H. S. Rye, Triggering protein folding within the GroEL-GroES chaperonin complex J.Biol.Chem. 283(46):32003-32013, 2008.
4. Z. Lin and H. S. Rye, GroEL-mediated protein folding: making the impossible, possible Crit. Rev. Biochem. Mol. Biol. (41):211–239, 2006.
5. Z. Lin and H. S. Rye, Expansion and compression of a protein folding intermediate by GroEL Mol. Cell 16 (1):23-34, 2004
6. G. Ren, Z. Lin, C. L. Tsou, and C. C. Wang, Effects of macromolecular crowding on the unfolding and the refolding of D-glyceraldehyde-3- phosphate dehydrogenase J. Protein Chem. 22 (5):431-439, 2003.
7. Z. Lin and X. M. Pan, Accurate prediction of protein secondary structural content. J. Protein Chem. 20 (3):217-220, 2001.
8. J. Li, Z. Lin, and C. C. Wang Aggregated proteins accelerate but do not increase the aggregation of D-glyceraldehyde-3-phosphate dehydrogenase - Specificity of protein aggregation J. Protein Chem. 20 (2):155-163, 2001.
9. Z. Lin, C. C. Wang, and C. L. Tsou High concentrations of D-glyceraldehyde-3-phosphate dehydrogenase stabilize the enzyme against denaturation by low concentrations of GuHCl Biochim. Biophys. Acta 1481 (2):283-288, 2000.
2. Z. Lin, D. Madan and H. S. Rye, GroEL stimulates protein folding through forced unfolding Nat. Struct. Mol. Biol. 15(3):303-311, 2008.
3. D. Madan, Z. Lin and H. S. Rye, Triggering protein folding within the GroEL-GroES chaperonin complex J.Biol.Chem. 283(46):32003-32013, 2008.
4. Z. Lin and H. S. Rye, GroEL-mediated protein folding: making the impossible, possible Crit. Rev. Biochem. Mol. Biol. (41):211–239, 2006.
5. Z. Lin and H. S. Rye, Expansion and compression of a protein folding intermediate by GroEL Mol. Cell 16 (1):23-34, 2004
6. G. Ren, Z. Lin, C. L. Tsou, and C. C. Wang, Effects of macromolecular crowding on the unfolding and the refolding of D-glyceraldehyde-3- phosphate dehydrogenase J. Protein Chem. 22 (5):431-439, 2003.
7. Z. Lin and X. M. Pan, Accurate prediction of protein secondary structural content. J. Protein Chem. 20 (3):217-220, 2001.
8. J. Li, Z. Lin, and C. C. Wang Aggregated proteins accelerate but do not increase the aggregation of D-glyceraldehyde-3-phosphate dehydrogenase - Specificity of protein aggregation J. Protein Chem. 20 (2):155-163, 2001.
9. Z. Lin, C. C. Wang, and C. L. Tsou High concentrations of D-glyceraldehyde-3-phosphate dehydrogenase stabilize the enzyme against denaturation by low concentrations of GuHCl Biochim. Biophys. Acta 1481 (2):283-288, 2000.
