胡鳳玉,女,出生於1972年12月,醫學博士/博士研究生,現任廣州醫科大學附屬市八醫院副院長、研究員。
2021年12月15日,被全國科技系統抗擊新冠肺炎疫情表彰工作領導小組辦公室擬表彰為全國科技系統抗擊新冠肺炎疫情先進個人,並予以公示。
基本介紹
人物經歷,研究方向,科研成果,
人物經歷
2003/9-2008/6,中山大學中山醫學院,病原生物學,博士;
1991/9 - 1996/7,皖南醫學院,臨床醫學,本科學士
2020/11-,廣州醫科大學附屬市八醫院,研究員,業務副院長
2014/1-2020. 10,廣州醫科大學,附屬市八醫院,副主任技師,傳染病研究所負責人
2011/11-2013/12,UNC-Chaple Hill, 醫學院傳染病系,博士後(合作導師:Stanley Lemon)
2008/7 -2011/10,廣州醫科大學,附屬市八醫院,副主任技師
2001/7-2003/8,皖南醫學院,生理學教研室,講師
1996/8-2001/6,皖南醫學院,生理學教研室,助教
研究方向
從事病毒性疾病的臨床基礎研究,主要研究方向為HIV及肝病病毒合併感染的致病機制及治療策略。
科研成果
科研項目和成果近3年來主持課題4項,撰寫相關學術論文多篇,其中一作或通訊作者SCI 論文13篇。
近3年來主持科研項目:
1. 項目類別:廣東省科技廳重點領域研發計畫項目;批准號:2020B1111330002;題目:“新冠病原現場快速檢測關鍵技術的研發”(子課題2); 研究起止年月:2020/06/01-2021/05/31;獲資助金額:150萬元,項目狀態:在研、子課題負責人
2. 項目類別:廣州市科技計畫項目;批准號:202002030028;題目:“HBV缺失突變與HIV/HBV合併感染者免疫重建延緩的關係及機制研究”; 研究起止年月:2020/04/01-2023/03/31;獲資助金額:20萬元,項目狀態:在研、課題負責人
3. 項目類別:科技部“十三.五”國家科技重大專項“愛滋病和病毒性肝炎等重大傳染病防治”項目;批准號:2017ZX10202101-001-003;題目:愛滋病綜合治療方案的最佳化及推廣套用研究(任務3);研究起止年月:2017/01-2020/12;獲資助金額:77.92萬,項目狀態:在研(因新冠疫情延期)、任務級課題負責人;
4. 項目類別:廣州市健康醫療協同創新重大專項;批准號:201704020219;題目:“性傳播疾病防控新技術研究和套用”; 研究起止年月:2017/03-2020/02;獲資助金額:35萬元,項目狀態:在研(因新冠疫情延期)、分課題負責人。
近3年主要論文:
1. Yuan Nie #, Xizi Deng# ,Yun Lan ,Linghua Li, Feng Li*, Fengyu Hu*. Comparison and Correlation of Genetic Variability of the HBV Pre-S Region in HIV/HBV Co-Infected Patients: Quasispecies Perspective. Infection and Drug Resistance 2020:13 4327–4334
2. Li L#, Liang Y#, Hu F#, Yan H, Li Y, Xie Z, Huang L, Zhao J, Wan Z, Wang H, Shui J, Cai W, Tang S. Molecular and serological characterization of SARS-CoV-2 infection among COVID-19 patients. Virology. 2020;551:26-35.
3. Hu F#, Chen F#, Ou Z#, Fan Q, Tan X, Wang Y, Pan Y, Ke B, Li L, Guan Y, Mo X, Wang J, Wang J, Luo C, Wen X, Li M, Ren P, Ke C, Li J, Lei C, Tang X, Li F. A compromised specific humoral immune response against the SARS-CoV-2 receptor-binding domain is related to viral persistence and periodic shedding in the gastrointestinal tract. Cell Mol Immunol. 2020;17(11):1119-1125
4. Lan Y, He X, Xin R, Li L, Huang X, Deng X, Tang X, Jia W, Cai W, Hu F*. Genetic Characteristics of HIV-1 CRF12_BF First Identified in Guangdong Province, China. AIDS Res Hum Retroviruses. 2021;37(2):157-161
5. Nie Y, Lan Y, Deng XZ, Li LH, Cai WP, Li F, Hu FY*. Assessing the association between platelets and immune recovery in HIV/HBV co-infected patients: A long-term cohort in Asia. Infect Genet Evol. 2020;84:104480
6. Nie Y, Deng XZ, Lan Y, Li F, Hu FY*. Pre-S Deletions are Predominant Quasispecies in HIV/HBV Infection: Quasispecies Perspective. Infect Drug Resist. 2020;13:1643-1649.
7. Lan Y, Xin R, Cai W, Deng X, Li L, Li F, Cai X, Tang X, Fan Q, Hu F*. Characteristics of drug resistance in HIV-1 CRF55_01B from ART-experienced patients in Guangdong, China. J Antimicrob Chemother. 2020;75(7):1925-1931.
8. Wan Z#, Liu J#, Hu F# (co-First author), Shui J, Li L, Wang H, Tang X, Hu C, Liang Y, Zhou Y, Cai W, Tang S. Evidence that the second human pegivirus (HPgV-2) is primarily a lymphotropic virus and can replicate independent of HCV replication.Emerg Microbes Infect. 2020;9(1):485-495
9. Weilie Chen, Yun Lan, Xiaozhen Yuan, Xilong Deng , Yueping Li , Xiaoli Cai , Liya Li , Ruiying He, Yizhou Tan, Xizi Deng , Ming Gao , Guofang Tang , Lingzhai Zhao , Jinlin Wang , Qinghong Fan , Chunyan Wen , Yuwei Tong , Yangbo Tang , Fengyu Hu* (co-Corresponding author), Feng Li*, Xiaoping Tang*. Detectable 2019-nCoV Viral RNA in Blood Is a Strong Indicator for the Further Clinical Severity . Emerg Microbes Infect, 2020,9 (1):469-473.
10. Gao M, Feng C, Ying R, Nie Y, Deng X, Zhu Y, Tang X, Guan Y, Hu F*(co-Corresponding author), Li F*. A novel one-step quantitative reverse transcription PCR assay for selective amplification of hepatitis B virus pregenomic RNA from a mixture of HBV DNA and RNA in serum. Arch Virol. 2019;164(11):2683-2690.
11. Li T, Lan Y, Li F, Li H, Deng H, Liu Y, Wang X, Han J, Jia L, Li J, Hu F* (co-Corresponding author), Li L. Characterization of Four Nearly Full-Length Genomic Sequences of HIV-1 Subtype G Identified in Guangdong Province, China. AIDS Res Hum Retroviruses. 2019;35(7):668-672
12. Jia L#, Hu F# (co-First author), Li H, Li L, Tang X, Liu Y, Deng H, Han J, Li J, Cai W. Characterization of small genomic regions of the hepatitis B virus should be performed with more caution. Virol J. 2018;15(1):188.
13. Deng H, Deng X, Liu Y, Xu Y, Lan Y, Gao M, Xu M, Gao H, Wu X, Liao B, Chen W, Zhao M, Hu F* (co-Corresponding author), Wang Z*. Naturally occurring antiviral drug resistance in HIV patients who are mono-infected or co-infected with HBV or HCV in China. J Med Virol. 2018;90(7):1246-1256.

