胡江苗

胡江苗,男,中國科學院大學專任教師。

基本介紹

  • 中文名:胡江苗
  • 國籍中國
  • 畢業院校:安徽中醫學院
  • 學位/學歷:博士
人物經歷,教育背景,工作經歷,研究方向,科研成果,專利成果,出版信息,科研項目,

人物經歷

教育背景

2002-09--2007-06 中國科學院研究生院 研究生學習/博士
1998-09--2002-06 安徽中醫學院 本科學習/學士

工作經歷

2007.7 – 2009.12, 中科院昆明植物所植化重點室助理研究員。
2010.1 – 今,中科院昆明植物所植化重點室副研究員。
2013年,遴選為中科院昆明植物所碩士研究生導師,。
2015年,雲南省中青年學術技術帶頭人後備人才。
2010-01~現在, 中國科學院昆明植物研究所, 副研究員
2007-07~2009-12,中國科學院昆明植物研究所, 助理研究員

研究方向

天然藥物化學
聚焦蘭科藥用植物,闡明主成分並進行活性探索與功能產品開發

科研成果

專利成果

( 1 ) 紫果西番蓮莖及葉提取物及其藥物組合物與抗抑鬱作用, 發明, 2013, 第 1 作者, 專利號: CN103040882 A
( 2 ) 一種鐵皮石斛複方製劑及其製備方法, 發明, 2017, 第 1 作者, 專利號: CN104147394A
( 3 ) 蜘蛛香環烯醚萜部位在製備N-型鈣通道抑制劑中的套用, 發明, 2015, 第 1 作者, 專利號: 201510066357.4
( 4 ) 一種山竹果殼中主要成分的製備方法及其在製藥中的套用, 發明, 2017, 第 1 作者, 專利號: CN107595922A
( 5 ) 白及屬植物中militarine部位及單體的製備方法及其套用, 發明, 2017, 第 1 作者, 專利號: CN107929544A
( 6 ) 美花石斛提取物及其在製備化妝品中的套用, 發明, 2018, 第 2 作者, 專利號: CN108042458A
( 7 ) 生物素-鬼臼毒素酯化衍生物及其藥物組合物和其製備方法與套用, 發明, 2014, 第 3 作者, 專利號: ZL2014103389435
( 8 ) 鬼臼毒素糖苷物和醯化糖苷物及其藥物組合物和其製備方法與套用, 發明, 2016, 第 3 作者, 專利號: ZL2013104952911

出版信息

發表論文
(1) Structural characterization and hypoglycemic effect via stimulating glucagon-like peptide-1 secretion of two polysaccharides from Dendrobium officinale., Carbohydrate Polymers, 2020, 通訊作者
(2) Three new compounds from the flower branch of Gastrodia elata Blume and anti-microbial activity, RSC Advances, 2020, 通訊作者
(3) Four new sesquiterpene derivatives from Dendrobium findlayanum, Chinese Journal of Natural Medicines, 2019, 通訊作者
(4) Phenolic Constituents with Antioxidative, Tyrosinase Inhibitory and Anti‑aging Activities from Dendrobium loddigesii Rolfe, Natural Products and Bioprospecting, 2019, 通訊作者
(5) Total synthesis of dryocrassin ABBA and its analogues with potential inhibitory activity against drug-resistant neuraminidases, Bioorganic & Medicinal Chemistry, 2019, 通訊作者
(6) Glucoside Derivatives of Podophyllotoxin: Synthesis, Physicochemical Properties, And Cytotoxicity, Drug Design, Development and Therapy, 2019, 通訊作者
(7) Design, Synthesis, and Biological Evaluation of Novel Biotinylated Podophyllotoxin Derivatives as Potential Antitumor Agents, Frontier Chemistry, 2019, 通訊作者
(8) Sesquiterpenoids from the roots and rhizomes of Valeriana amurensis and their effects on NGF-induced neurite outgrowth in PC12 cells, Natural Product Research, 2019, 通訊作者
(9) Synthesis and antitumor activity of camptothecin-4β-triazolopodophyllotoxin conjugates, Natural Product Research, 2019, 通訊作者
(10) 13,27-Cycloursane, ursane and oleanane triterpenoids from the leaves of Lucuma nervosa, Fitoterapia, 2019, 通訊作者
(11) Stilbenes with anti-inflammatory and cytotoxic activity from the rhizomes of Bletilla ochracea Schltr, Fitoterapia, 2018, 通訊作者
(12) Structural elucidation and antioxidant activity of an arabinogalactan from the leaves of Moringa oleifera, International journal of biological macromolecules, 2018, 通訊作者
(13) Seco-Dendrobine-Type Alkaloids and Bioactive Phenolics from Dendrobium findlayanum, Journal of Natural Products, 2018, 通訊作者
(14) Design, synthesis and structure-activity relationships of mangostin analogs as cytotoxic agents, RSC Advance, 2018, 通訊作者
(15) Triterpenoids and iridoids from Patrinia scabiosaefolia, Fitoterapia, 2017, 通訊作者
(16) Ca v 2.2 and Ca v 3.1 calcium channel inhibitors from Valeriana jatamansi Jones, RSC Advances, 2017, 通訊作者
(17) Sesquiterpene amino ether and cytotoxic phenols from Dendrobium wardianum Warner, Fitoterapia, 2017, 通訊作者
(18) Polysaccharides of Dendrobium officinale Kimura & Migo protect gastric mucosal cell against oxidative damage-induced apoptosis in vitro and in vivo, Journal of Ethnopharmacology, 2017, 通訊作者
(19) Triterpenoids and iridoids from Patrinia scabiosaefolia, Fitoterapia, 2017, 通訊作者
(20) Iridoids and bis-iridoids from Patrinia scabiosaefolia, RSC advance, 2017, 通訊作者
(21) Four new glycosides from the stems of Dendrobium fimbriatum Hook, Natural Product Research, 2017, 通訊作者
(22) Structural characterization and immunomodulating activity of polysaccharide from Dendrobium officinale, International Journal of Biological Macromolecules, 2016, 通訊作者
(23) Oleanane-type triterpene saponins from Hydrocotyle nepalensis, Fitoterapia, 2016, 通訊作者
(24) Protective effects of cycloartane triterpenoides from Passiflora edulis Sims against glutamate-induced neurotoxicity in PC12 cell, Fitoterapia, 2016, 通訊作者
(25) Volvalerine A, an unprecedented N-containing sesquiterpenoid dimer derivative from Valeriana officinalis var. latifolia, Fitoterapia, 2016, 通訊作者
(26) Iridoids and sesquiterpenoids of Valeriana stenoptera and their effects on NGF-induced neurite outgrowth in PC12 cells, Phytochemistry, 2015, 通訊作者
(27) 全丁醯糖基化鬼臼毒素修飾物及其抗腫瘤活性, Synthesis and antitumor activity of novel per-butyrylated glycosides of podophyllotoxin and its derivatives, Bioorganic Medicinal Chemistry, 2015, 通訊作者
(28) 蜘蛛香環烯醚萜與倍半萜, Iridoids and sesquiterpenoids from the roots of Valeriana jatamansi Jones, Fitoterapia, 2015, 通訊作者
(29) 全丁醯糖基化4β三唑環鬼臼毒素的設計合成與腫瘤細胞毒活性評價, Design, synthesis, and cytotoxicity of per-butyrylated glycosides of 4β-triazole-podophyllotoxin derivatives, Molecules, 2015, 通訊作者
(30) 流蘇石斛中抗腫瘤活性聯苄, Cytotoxic bibenzyl dimers from the stems of Dendrobium fimbriatum Hook, Bioorganic Medicinal Chemistry Letters, 2014, 通訊作者
(31) 兜唇石斛中5個新酚類化合物, Five new phenolic compounds from Dendrobium aphyllum, Fitoterapia, 2014, 通訊作者
(32) 鐵皮石斛中兩個新的具有神經營養作用的鐵皮石斛素, Two New dendrocandins and neurite outgrowth-promoting activity from Dendrobium officinale, Journal of Asian Natural Products Research, 2014, 通訊作者
(33) Synthesis and Anticancer Activity of Glucosylated Podophyllotoxin Derivatives Linked via 4β-Triazole Rings, Molecules, 2013, 通訊作者
(34) Nardokanshone A, a new type of sesquieterpenoid–chalcone hybrid from Nardostachys chinensis, Tetrahedron Letters, 2013, 通訊作者
(35) Inhibitory activities on nitric oxide production of stilbenoids from Pholidota yunnanensis, Journal of Asian Natural Products Research, 2013, 通訊作者
(36) C-dideoxyhexosyl flavones from the stems and leaves of Passiflora edulis Sims, Food Chemistry, 2013, 通訊作者
(37) Dendrowardols A and B, Two New Sesquiterpenoids from Dendrobium wardianum Warner, Tetrahedron Letters, 2013, 通訊作者
(38) Dendrowardol C, a novel sesquiterpenoid from Dendrobium wardianum, Natural Products and Bioprospecting, 2013, 通訊作者
(39) Chemical components of Dendrobium crepidatum and their neurite outgrowth enhancing activities, Natural Products and Bioprospecting, 2013, 通訊作者
(40) Cycloartane Triterpenoid Saponins from water soluble of Passiflora edulis Sims and their antidepressant-like effects, Journal of Ethnopharmacology, 2013, 通訊作者

科研項目

( 1 ) 雲南鐵皮石斛深加工關鍵技術研究和產業化, 參與, 省級, 2013-12--2016-11
( 2 ) 石斛總酚的套用開發研究, 主持, 研究所(學校), 2013-12--2016-11
( 3 ) 生物素及糖苷化修飾鬼臼毒素類似物抗腫瘤藥物研發, 主持, 省級, 2015-07--2018-06
( 4 ) 石斛抗衰老、美白及石斛花芳香物質研究, 主持, 院級, 2016-08--2019-08
( 5 ) 石斛的安全性和新功能的開發, 主持, 院級, 2018-01--2020-12
( 6 ) 鐵皮石斛功能組分新功效研究與套用, 主持, 省級, 2017-01--2019-12
( 7 ) 雲貴高原植物代謝物的分離及製備, 主持, 國家級, 2017-07--2020-12

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