熊鵬，中國科學技術大學生物醫學工程特任研究員、博士生導師。
人物經歷,研究方向,學術論文,
人物經歷
2023/03-至今，中國科大蘇州高等研究院，特任研究員
2021/05-2023/03，上海智峪生物科技有限公司，CTO
2018/05-2021/05，澳大利亞格里菲斯大學，博士後
2016/08-2018/05，中國科學技術大學，博士後
2015/06-2016/06，美國密西根大學，博士後
研究方向
1.RNA三維結構預測
2.蛋白質設計
3.功能RNA分子設計及蛋白質核酸相互作用設計
獲獎及榮譽情況
2022年結構預測大賽CASP15 RNA組第一名
學術論文
1.Peng Xiong*, Meng Wang*, Xiaoqun Zhou, Tongchuan Zhang, Jiahai Zhang, Quan Chen, and Haiyan Liu. "Protein design with a comprehensive statistical energy function and boosted by experimental selection for foldability." Nature communications 5 (2014).
2.Xiaoqun Zhou, Peng Xiong, Meng Wang, Rongsheng Ma, Jiahai Zhang, Quan Chen, and Haiyan Liu. "Proteins of well-defined structures can be designed without backbone readjustment by a statistical model." Journal of Structural Biology 196, no. 3 (2016): 350-357
3. Peng Xiong, Chengxin Zhang, Wei Zheng, and Yang Zhang. "BindProfX: Assessing mutation-induced binding affinity change by protein interface profiles with pseudo counts." Journal of Molecular Biology (2016).
4. Peng Xiong, Quan Chen, and Haiyan Liu. "Computational Protein Design Under a Given Backbone Structure with the ABACUS Statistical Energy Function." Methods Mol Biol1529, 217-226 (2017).
5. Peng Xiong, Xiuhong Hu, Bin Huang, Jiahai Zhang, Quan Chen, and Haiyan Liu. "Increasing the efficiency and accuracy of the ABACUS protein sequence design method." Bioinformatics 36, no. 1 (2020).
6. Zhe Zhang*, Peng Xiong*, Tongchuan Zhang, Junfeng Wang, Jian Zhan and Yaoqi Zhou, Accurate inference of the full base-pairing structure of RNA by deep mutational scanning and covariation-induced deviation of activity, Nucleic Acid Research (2020).
7. Peng Xiong , Ruibo Wu, Jian Zhan and Yaoqi Zhou. Pairing a high-resolution statistical potential with a nucleobase-centric sampling algorithm for improving RNA model refinement, Nature Communications (2021).
