潘榮清，Rongqing Aaron Pan，PhD，PI, 博導，國家級海外高層次青年人才，浙江大學醫學院“百人計畫”研究員，浙江大學附屬第一醫院雙聘教授。
潘榮清畢業於MD Anderson Cancer Center (ranked No.1 in Cancer Care)，之後在哈佛醫學院/Dana-Farber Cancer Institute從事博士後研究。潘博士求學期間獲得多項獎勵, 包括AAAS/Science Program for Excellence、Presidents’ Research Scholarship、Lasher and Longoria Research Award, 哈佛華人生命科學傑出研究獎、美國血液學會Abstract Achievement Award等。其科研成果已在Harvard、MD Anderson，Stanford、Memorial Sloan Kettering等20多個頂尖癌症中心進行臨床試驗，並促成FDA批准一款新藥維奈托克用於治療復發/難治白血病。
截至2023年4月，在Cell (通訊，唯一一作)，Cancer Cell（唯一一作）和Cancer Discovery (兩並一排一)、BLOOD (唯一作者)等期刊發表了研究長文。上述四篇代表作均為高被引論文，其中三篇連續多月為ESI熱點論文，其中一篇預印版+最終版累計被引~800次。上述一作代表作先後被Cell， Nat Rev Drug Disc, Science, Cancer Discovery, Cancer Cell等頂尖學術期highlighted、featured以及邀請國際專家評述，並被Dana-Farber、MD Anderson等頂尖癌症機構、國外媒體和國內中國科技部、BioArt、科學網等報導。潘榮清博士同時擔任多個主流學術期刊審稿人和一個國外癌症基金評審（2020-2023）。
基本介紹
- 中文名：潘榮清
- 外文名：Rongqing Aaron Pan
- 畢業院校：美國德克薩斯大學MD Anderson Cancer Center
- 學位：博士
- 職稱：研究員
- 博士後：哈佛醫學院 Dana-Farber Cancer Institute
研究方向,代表文章,主要成就,主要獎項,
研究方向
腫瘤免疫學與免疫治療
NK & T細胞療法
線粒體凋亡與精準靶向治療
免疫與靶向聯合療法
代表文章
Pan R* (唯一一作，通訊作者), Ryan J, Pan D, Wucherpfennig K, Letai A.Augmenting NK cell-Based Immunotherapy by Targeting Mitochondrial Apoptosis. Cell , 期刊IF(2022)=66.85
Pan R (唯一一作), Vivian R, Mu H … Andreeff M. Synthetic Lethality of Combined BCL-2 Inhibition and p53 Activation in AML: Mechanisms and Superior Antileukemic Efficacy. Cancer Cell, 期刊IF(2022)=38.59
Pan R, Hogdal L(並列一作), Benito J, …. Konopleva M, Letai A. Selective BCL-2 inhibition by ABT-199 causes on-target cell death in acute myeloid leukemia. Cancer Discovery 期刊IF(2022)=38.27
Pan R (唯一一作), Vivian R, Wei J, Konopleva M, …Andreeff M*. Inhibition of MCL-1 with the pan-BCL-2 family inhibitor (-)BI97D6 overcomes ABT-737 resistance in acute myeloid leukemia. Blood 期刊IF(2022)=25.48
Pan R (唯一一作), Wang Y, Ensar M, Ryan J,Letai A*. Dynamic BH3 Profiling as a Pharmacodynamic Biomarker for the Activity of BH3 Mimetic Coumpounds, Haematologica，In Press 期刊IF(2022)=11.05
Pan, R （唯一一作）, Zhang, J., Shen, W.L., Tao, Z.Q., Li, S.P., and Yan, X. Sequential deletion of Pichia pastoris genes by a self-excisable cassette. FEMS yeast research
Yao-Chung Liu … Pan R（共同作者） …Li Chai. Demethylation and upregulation of an oncogene post hypomethylating treatment. New England Journal of Medicine
Jiang X … Pan R（共同作者） … Carter B. Disruption of Wnt/beta-Catenin Exerts Antileukemia Activity and Synergizes with FLT3 Inhibition in FLT3-Mutant Acute Myeloid Leukemia. Clinical Cancer Research
Han L … Pan R（共同作者）… Konopleva M. Antileukemia Efficacy and Mechanisms of Action of SL-101, a Novel Anti-CD123 Antibody Conjugate, in Acute Myeloid Leukemia. Clinical Cancer Research
Qi Zhang… Pan R（共同作者）… Konopleva, M. Activation of RAS/MAPK pathway confers MCL-1 mediated acquired resistance to BCL-2 inhibitor venetoclax in acute myeloid leukemia. Signal Transduction & Targeted Tharapy
主要成就
潘榮清博士多次在美國血液協會(ASH)、美國癌症協會(AACR)、冷泉港實驗室(CSHL)和哈佛機構等學術會議做口頭和牆報報告。其工作不僅可以給癌症新療法、增強免疫治療、克服腫瘤耐藥性提供基礎理論依據，同時也具有重要臨床指導意義。例如其科研成果已在美加法意四國的DFCI/Harvard、MD Anderson，Stanford、Memorial Sloan Kettering，Princess Margaret等20多個頂尖癌症中心進行臨床試驗，並促成FDA批准一款新藥(venetoclax/ABT-199)用於治療復發/難治白血病。
截至2023年4月，在Cell (通訊，唯一一作)，腫瘤學頂刊Cancer Cell（唯一一作）和Cancer Discovery (兩並一排一)、血液頂刊BLOOD (唯一作者)等期刊發表了研究長文。其中Cell、Cancer Cell文章為潘博士從Idea到Publication自行設計並高度獨立完成的課題。上述四篇代表作均為ESI高被引論文，其中三篇連續多月為ESI熱點論文，其中一篇預印版+最終版累計被引~800次(Google Scholar截至)。上述一作代表作先後被Cell， Nat Rev Drug Disc, Science, Cancer Discovery, Cancer Cell, Science Transl Med等頂尖學術期highlighted、featured以及邀請國際專家評述，並被Dana-Farber、MD Anderson、 Ludwig Institute等頂尖癌症機構、國外眾多科學類媒體和國內的中國科技部、網易、BioArt、科學網、生物世界等報導。潘榮清博士同時擔任多個主流學術期刊審稿人和一個國外癌症基金評審（2020-2023）。
主要獎項
2023國家級高層次青年人才
2022Harvard Life Sciences Distinguished Chinese Scholar Award (哈佛華人生命科學傑出研究獎)
2022Featured Article Collection at AACR-San Diego 2022
2021The Most Impactful Papers at Cancer Discovery 10th Anniversary (10 selected from ＞1000 papers)
2020Abstract Achievement Award at American Society of Hematology(ASH) Annual Conference
2017Alfred G. Knudson, Jr. Best Dissertation Award (Finalist, 2nd place), MD Anderson Cancer Center and UThealth
2016Lasher and Longoria Graduate Student Research Award in Cancer Biology, MD Anderson Cancer Center and UTHealth
2015國務院副總理訪美留學生代表
2015Presidents’ Research Scholarship, MD Anderson Cancer Center and UT Health Science Center
2015AAAS/Science Program for Excellence in Science, American Association for the Advancement of Science (AAAS & Science Journal)
2015 Andrew Sowell-Wade Huggins Endowed Scholarship, Andrew Sowell-Wade Huggins Endowed Scholarship Fund
2015 Abstract Achievement Award, American Society of Hematology Annual Meeting
2015 GSBS Travel Award, MD Anderson Cancer Center and UT Health Sciences Center
2014 Abstract Achievement Award, American Society of Hematology Annual Meeting（ASH）
2014中國優秀留學生獎學金Chinese Government Award for Outstanding Students Abroad, Ministry of Education, China （教育部）
2014 MD Anderson Alumni and Faculty Association Graduate Student Award. Trainee Research Day, MD Anderson Cancer Center
2014 GSBS Travel Award, MD Anderson Cancer Center and UTHealth
2013 MD Anderson Alumni and Faculty Association Graduate Student Award. Trainee Research Day, MD Anderson Cancer Center
2013 GSBS Travel Award, MD Anderson Cancer Center and UTHealth，etc
多年 博士生全額獎學金，（UT MD Anderson and UTHealth Grad Schl of Biomed Science）
