沈傳來

沈傳來

沈傳來,男,東南大學醫學院教授

基本介紹

  • 中文名:沈傳來
  • 職業:教師
  • 專業方向:腫瘤的免疫生物療法研究
  • 任職院校:東南大學醫學院
個人經歷,研究方向,榮譽獎項,學術成果,

個人經歷

碩士畢業於上海第二醫科大學、上海市免疫學研究所;博士於東南大學醫學院遺傳與發育生物學系;2003-2013年間曾分別在美國紐約州立大學布法羅大學Roswell Park腫瘤研究所免疫學全紋雄系、香港中文大學生物醫學學院和澳大利亞墨爾本Monash大學生物醫學學院等地做訪問婆己臭懂學者。

研究方向

1、腫瘤的免疫生物療法研究
2、移植排斥的免疫生物療法研究
3、免疫學新技術的研究

榮譽獎項

1、獲東南大學教學優秀二等獎一次
2、獲東南大學獎教金一次
2、2012年入選江蘇省教育廳江蘇高校“青藍工程”中青年學術帶頭人培養計畫

學術成果

作為負責人目兆乎前正在主持的科研項目:
1. 國家自然科學基金面上項目:
多功能PLGA微粒式人工抗原提呈細胞對腫瘤的主動免疫治療
項目號:81372448;2014-2017年
2. 國家自拳籃淚然科學基金面上項目:
PLGA納米球吸附MHC同種抗原和負調節分子誘導皮膚移植耐受的研究
項目號糠檔拘:81172823;2012-2015年
3. 江蘇省科技支撐計畫項目:
磁性人工抗原提呈細胞微孔反應板的研製及特異性細胞免疫功能的檢測
項目號:BE2012739;2012-1015年
作為項目負責人已完成的科研項目:
1. 國家自然科學基金面上項目:
膠乳微球式人工抗原提呈細胞誘導抗腫瘤主動免疫反應的研究,
項目號:30771998;2008-2010年
2. 江蘇省科技廳社會發展項目:
HCV ISDR突變在預測干擾素治療慢性C型肝炎療效中的臨床意戒采閥懂義,記臘匙
項目號:BS2007046;2007-2010年
3.東南大學重大科研計畫引導項目:(與東南大學物理系合作課題)
基於表面增強光譜技術的醫學單分子單細胞診斷
項目號:2011-15;2011-2012年
近期的代表性論文:
1.Chuanlai Shen,Kai Cheng, Shenwei Miao, Wei Wang, Yong He, Fanyan Meng, Jianqiong Zhang. Latex bead-based artificial antigen-presenting cells induce tumor-specific CTL responses in the native T-cell repertoires and inhibit tumor growth. Immunology Letters, 2013; 150(1-2): 1-11.
2.Chuanlai Shen,Yong He, Fanyan Meng, Kai Cheng, Daoping Zhang, Fengqin Miao, Jianqiong Zhang. Characterization of MHC/peptide complexes refolded by a one-step ion-exchange chromatography.Journal of Iommunological Methods, 2011;369(1-2): 81-90.
3.Chuanlai Shen,Yong He, Kai Cheng, Daoping Zhang, Shenwei Miao, Aifeng Zhang, Fanyan Meng, Fengqin Miao, Jianqiong Zhang. Killer artificial antigen-presenting cells deplete alloantigen-specific T cells in a murine model of alloskin transplantation.Immunology Letters,2011; 138(2): 144-155.
4.Fanyan Meng,Chuanlai Shen,Fengqin Miao, Yong He, Wei Xie, Jianqiong Zhang.A novel one-step strategy for the preparation of HLA/HBc(18-27) and HLA/CEA (694-702) complexes with ion exchange chromatography.Biotechnology Letter,2010; 32(12): 1803-8.(SCI論文)
5.Fanyan Meng,Chuanlai Shen,Yong He, Fengqin Miao, Jianqiong Zhang. Cloning and expression of three peptide-linked β2-microglobulin molecules in Escherichia coli with an isocaudamer technique.Biotechnology Letter,2009; 31(6): 831-6.(SCI論文)
6.Chuanlai Shen,Jianqiong Zhang, Lingzhi Xia, Fanyan Meng, Wei Xie. Induction of tumor antigen-specific cytotoxic T cell responses in naïve mice by microspheres-based artificial antigen-presenting cell constructs.Cellular Immunology,2007; 247(1): 28-35.
7.Chuanlai Shen, Ting Hu, Ling Shen, Lei Gai, Wei Xie, Jianqiong Zhang. Mutations in ISDR of NS5Agene influenceinterferon efficacy in Chinese patients with chronic hepatitis C virus genotype 1b infection.Journal of Gastroenterology and Hepatology,2007; 22(1): 1898-903.)
8.Chuanlai Shen,Chien-Chung Chang, Jianqiong Zhang, Wei Guo, Lingzhi Xia, Fanyan Meng, Wei Xie. Structural and functional characterization of peptide-β2mfused HLA-A2/MART127-35complexes.Biochemical and Biophysical Research Communications,2006; 342: 57-65.
9.Chuanlai Shen,Chien-Chung Chang, Jianqiong Zhang, Wei Guo, Fanyan Meng, Wei Xie. Construction of HLA/peptide tetramer with peptide-linked β2 microglobulin.Journal of Microbiology and Immunology,2004; 2(4): 286-294. (中華微生物學與免疫學雜誌的英文版)
3.Chuanlai Shen,Yong He, Kai Cheng, Daoping Zhang, Shenwei Miao, Aifeng Zhang, Fanyan Meng, Fengqin Miao, Jianqiong Zhang. Killer artificial antigen-presenting cells deplete alloantigen-specific T cells in a murine model of alloskin transplantation.Immunology Letters,2011; 138(2): 144-155.
4.Fanyan Meng,Chuanlai Shen,Fengqin Miao, Yong He, Wei Xie, Jianqiong Zhang.A novel one-step strategy for the preparation of HLA/HBc(18-27) and HLA/CEA (694-702) complexes with ion exchange chromatography.Biotechnology Letter,2010; 32(12): 1803-8.(SCI論文)
5.Fanyan Meng,Chuanlai Shen,Yong He, Fengqin Miao, Jianqiong Zhang. Cloning and expression of three peptide-linked β2-microglobulin molecules in Escherichia coli with an isocaudamer technique.Biotechnology Letter,2009; 31(6): 831-6.(SCI論文)
6.Chuanlai Shen,Jianqiong Zhang, Lingzhi Xia, Fanyan Meng, Wei Xie. Induction of tumor antigen-specific cytotoxic T cell responses in naïve mice by microspheres-based artificial antigen-presenting cell constructs.Cellular Immunology,2007; 247(1): 28-35.
7.Chuanlai Shen, Ting Hu, Ling Shen, Lei Gai, Wei Xie, Jianqiong Zhang. Mutations in ISDR of NS5Agene influenceinterferon efficacy in Chinese patients with chronic hepatitis C virus genotype 1b infection.Journal of Gastroenterology and Hepatology,2007; 22(1): 1898-903.)
8.Chuanlai Shen,Chien-Chung Chang, Jianqiong Zhang, Wei Guo, Lingzhi Xia, Fanyan Meng, Wei Xie. Structural and functional characterization of peptide-β2mfused HLA-A2/MART127-35complexes.Biochemical and Biophysical Research Communications,2006; 342: 57-65.
9.Chuanlai Shen,Chien-Chung Chang, Jianqiong Zhang, Wei Guo, Fanyan Meng, Wei Xie. Construction of HLA/peptide tetramer with peptide-linked β2 microglobulin.Journal of Microbiology and Immunology,2004; 2(4): 286-294. (中華微生物學與免疫學雜誌的英文版)

相關詞條

熱門詞條

聯絡我們