汪超，蘇州大學功能納米與軟物質研究院教授、博士生導師，國家優秀青年科學基金獲得者，江蘇省特聘教授。2010年獲蘇州大學生物科學專業學士學位，2014年獲該校化學生物學專業博士學位，2015-2018年在美國北卡州立大學與教堂山分校從事博士後研究，2018年入職蘇州大學。
課題組聚焦生物材料與免疫工程交叉領域，發展通用化平台技術，設計新型工程化生物材料與智慧型遞釋系統，提出多種疾病免疫治療新策略。在Nature Nanotechnology、Science Advances、Cell Reports等期刊發表通訊作者論文40餘篇，總SCI論文100餘篇，H指數75，獲授權發明專利10項。主持國家重點研發計畫青年項目、國家自然科學基金優秀青年科學基金等項目。入選全球高被引科學家（2018-2023）、TR35 Asia Pacific（2021），獲JNB Rising Star Award（2023）。
人物經歷,研究領域,代表論文,
人物經歷
2010年獲蘇州大學生物科學專業學士學位；
2014年獲蘇州大學化學生物學專業博士學位；
研究領域
課題組長期圍繞生物材料與免疫工程交叉領域，利用工程學和材料學的技術手段，發展了一系列通用化平台技術，通過設計新型工程化生物材料、構建智慧型遞釋系統、發展創新生物技術，提出了多種疾病免疫治療技術的新策略，為解決免疫治療面臨的共性問題和挑戰提供了新的思路。迄今為止在國際學術期刊共發表SCI論文100餘篇，以通訊作者在Nature Nanotechnology、Nature Communications、Science Advances、Cell Reports等學術刊物上發表論文40餘篇，H-index 75，申請多項發明專利，授權10項，轉讓2項。作為項目負責人主持國家重點研發計畫青年項目、基金委優秀青年科學基金等。
代表論文
[19] Yue Zhang, Chenmeng Zhou, Bo Tian, Jialu Xu, Xiaoyu Wang, Huaxing Dai, Heng Wang, Fang Xu, Chao Wang*. 3D Printed Spiral Tube-like Cellulose Scaffold for Oral Delivery of Probiotics. Science Advances (2024) In press
[18] Jialu Xu, Yue Yu, Yue Zhang, Huaxing Dai, Qianyu Yang, Beilei Wang, Qingle Ma, Yitong Chen, Fang Xu, Xiaolin Shi, Zhuang Liu*, Chao Wang*. Oral administration of garlic-derived nanoparticles improves cancer immunotherapy by inducing intestinal IFNγ-producing γδ T cells, Nature Nanotechnology, 2024 Link
[17] Qingle Ma, Chenlu Yao, Yi Wu, Heng Wang, Qin Fan, Qianyu Yang, Jialu Xu, Huaxing Dai, Yue Zhang, Fang Xu, Ting Lu, Jennifer K. Dowling, Chao Wang*. Neurological Disorders after Severe Pneumonia are Associated with Translocation of Endogenous Bacteria from The Lung to The Brain. Science Advances, 9, eadi0699 (2023) Link
[16] Fang Xu, Dongpeng Jiang, Jialu Xu, Huaxing Dai, Qin Fan, Ziying Fei, Beilei Wang, Yue Zhang, Qingle Ma, Qianyu Yang, Yitong Chen, Edikan A. Ogunnaike, Jianhong Chu*, Chao Wang*. Engineering of Dendritic Cell Bispecific Extracellular Vesicles for Tumor Targeting Immunotherapy. Cell Reports, 42, 113138 (2023)
[15] Qianyu Yang, Huaxing Dai, Beilei Wang, Jialu Xu, Yue Zhang, Yitong Chen, Qingle Ma, Fang Xu, Haibo Chen, Dongdong Sun*, Chao Wang*. Nanoplastics Shape Adaptive Anticancer Immunity in the Colon in Mice. Nano Letters, 23, 3516 (2023).
[14] Qianyu Yang#, Huaxing Dai#, Ying Cheng#, Beilei Wang, Jialu Xu, Yue Zhang, Yitong Chen, Fang Xu, Qingle Ma, Fang Lin* and Chao Wang*. Oral Feeding of Nanoplastics affects Brain function of Mice by Inducing Macrophage IL-1 signal in Intestine. Cell Reports, 42, 112346 (2023).
[13] Yitong Chen, Yue Zhang, Beilei Wang, Qin Fan, Qianyu Yang, Jialu Xu, Huaxing Dai, Fang Xu, Chao Wang*. Blood Clot Scaffold Load with Liposome Vaccine and siRNAs Targeting PD-L1 and TIM-3 for Effective DC Activation and Cancer Immunotherapy. ACS Nano, 17, 760 (2023). Link
[12] Fang Xu*, Yi Wu, Qianyu Yang, Ying Cheng, Jialu Xu, Yue Zhang, Huaxing Dai, Beilei Wang, Qingle Ma, Yitong Chen, Fang Lin, Chao Wang*. Engineered extracellular vesicles with SHP2 high expression promote mitophagy for Alzheimer’s disease treatment. Advanced Materials, 2207107, (2022). Link
[11] Beilei Wang, Jinyu Bai*, Bo Tian, Hao Chen, Qianyu Yang, Yitong Chen, Jialu Xu, Yue Zhang, Huaxin Dai, Qingle Ma, Ziyin Fei, Heng Wang, Fang Xu, Xiaozhong Zhou*, Chao Wang*. Genetically Engineered Hematopoietic Stem Cells Deliver TGF-β Inhibitor to Enhance Bone Metastases Immunotherapy. Advanced Science, 2201451 (2022). Link
[10] Jialu Xu, Qingle Ma, Yue Zhang, Ziying Fei, Yifei Sun, Qin Fan, Bo Liu, Jinyu Bai, Yue Yu, Jianhong Chu*, Jingrun Chen*, Chao Wang*. Yeast-derived nanoparticles remodel the immunosuppressive microenvironment in tumor and tumor-draining lymph nodes to suppress tumor growth. Nature Communications, 13, 110 (2022). Link
[9] Huaxing Dai, Qin Fan, Ziying Fei, Qingle Ma, Qianyu Yang, Jiacheng Chu, Xuanfang Zhou, Yue Zhang, Ziliang Dong, Fang Xu, Beilei Wang, Rong Sun, Yifan Shen, Ruao Xie, Ruibin Li and Chao Wang*. Systemically Administered Silica Nanoparticles Result in Diminished T cell Response in Lung. Nano Today42, 101332 (2022). Link
[8] Qin Fan#, Huaxing Dai#, Jinyu Bai#, Jialu Xu, Qingle Ma, Ziying Fei, Xiaozhong Zhou*, Kam W. Leong*, Chao Wang*. Degradation-resistant Implanted Biomaterials Establish an Immunosuppressive Microenvironment that Induces T Cell Exhaustion by Recruiting Myeloid Cells. Fundamental Research (2022). Link
[7] Fang Xu, Ziying Fei, Huaxing Dai, Jialu Xu, Qin Fan, Shufang Shen, Yue Zhang, Qingle Ma, Jiacheng Chu, Fei Peng, Fangfang Zhou, Zhuang Liu, Chao Wang*. Mesenchymal Stem Cell-derived Extracellular Vesicles with High PD-L1 Expression for Autoimmune Diseases Treatment. Advanced Materials, 34, 2106265 (2022). Link
[6] Yue Zhang, Jialu Xu, Ziying Fei, Huaxing Dai, Qin Fan, Qianyu Yang, Yitong Chen, Beilei Wang, Chao Wang*. 3D Printing Scaffold Vaccine for Antitumor Immunity. Advanced Materials, 33, 2106768 (2021). Link
[5] Shufang Shen, Huaxing Dai, Ziying Fei, Yu Chai, Yu Hao, Qin Fan, Ziliang Dong, Yujie Zhu, Jialu Xu, Qingle Ma, Xiao Han, Ligeng Xu, Fei Peng, Zhuang Liu, Chao Wang*. Immunosuppressive Nanoparticles for Management of Immune-Related Adverse Events in Liver. ACS Nano, 5, 9111 (2021). Link
[4] Qin Fan, Qingle Ma, Jinyu Bai, Jialu Xu, Ziying Fei, Ziliang Dong, Atsushi Maruyama, Kam W. Leong, Zhuang Liu and Chao Wang*. An Implantable Blood Clot-based Immune Niche for Enhanced Cancer Vaccination. Science Advances, 6, eabb4639 (2020). Link[Biotechscope]
[3] Qingle Ma, Qin Fan, Jialu Xu, Jinyu Bai, Xiao Han, Ziliang Dong, Xiaozhong Zhou, Zhuang Liu, Zhen Gu* and Chao Wang*. Calming Cytokine Storm in Pneumonia by Targeted Delivery of TPCA-1 Using Platelet-derived Extracellular Vesicles. Matter, 3, 287 (2020). Link[Matter]
[2] Xuanfang Zhou, Zhouqi Meng*, Jialin She, Yaojia Zhang, Xuan Yi, Hailin Zhou, Jing Zhong, Ziliang Dong, Xiao Han, Muchao Chen, Qin Fan, Kai Yang and Chao Wang*. Near-Infrared Light-Responsive Nitric Oxide Delivery Platform for Enhanced Radioimmunotherapy. Nano-Micro Letters, 12, 100 (2020).
[1] Xiao Han#, Shufang Shen#, Qin Fan, Guojun Chen, Edikan Archibong, Gianpietro Dotti, Zhuang Liu*, Zhen Gu* and Chao Wang*. Red Blood Cell Derived Nanoerythrosome for Antigen Delivery with Enhanced Cancer Immunotherapy. Science Advances, 5, eaaw6870 (2019).
