江賜忠

江賜忠，男，1974年生，福建人，美國愛荷華州州立大學博士，同濟大學生命科學與技術學院，博士生導師，科技部973重大專項首席科學家，同濟大學轉化醫學高等研究院教授，課題組組長。

基本介紹

• 中文名：江賜忠
• 畢業院校：美國愛荷華州州立大學
• 學位/學歷：博士
• 專業方向：生物信息學，基因組學，表觀遺傳組學
• 職務：同濟大學轉化醫學高等研究院課題組組長

研究方向

(1) 核小體重排和染色質結構變化對果蠅胚胎髮育的影響
(2) 核小體排列分布及其在基因調控中的作用
(3) 組蛋白修飾在核小體重排中的作用機理
(4) 核小體定位序列的識別，DNA序列變化對染色質結構的影響
(5) 分子進化學

人物經歷

1995 年畢業於天津南開大學，獲學士學位。1998年畢業於天津南開大學，獲碩士學位。2004年畢業於美國愛荷華州州立大學，獲遺傳學博士學位，並輔修生物信 息學和計算機科學。畢業後先後在美國冷泉港實驗室、維吉尼亞聯邦大學、賓夕法尼亞州州立大學進行博士後研究。2009年應聘為同濟大學特聘教授。

代表文章

1. Jiang, C and Pugh BF. (2009) A compiled and systematic reference map of nucleosome positions across the Saccharomyces genome. Genome Biology, 10:R109

2. Koerber RT, Rhee HS, Jiang C, Pugh BF. (2009) Interaction of transcriptional regulators with specific nucleosomes across the Saccharomyces genome. Mol Cell.35(6):889-902

3. Jiang, C and Pugh BF. (2009) Nucleosome positioning and gene regulation: advances through genomics. Nature Reviews Genetics, 10(3):161-72 Cover Story

4. Mavrich TN, Jiang C(Co-first author), Ioshikhes IP, Li X, Venters BJ, Zanton SJ, Tomsho LP, Qi J, Glaser RL, Schuster SC, Gilmour DS, Albert I, Pugh BF. (2008) Nucleosome organization in the Drosophila genome. Nature, 453(7193):358-62 Article

5. Mavrich, TN, Ioshikhes, IP, Venters, BJ, Jiang, C, Tomsho, LP, Qi, J, Schuster, SC, Albert, I, and Pugh, BF (2008) A barrier nucleosome model for statistical positioning of nucleosomes throughout the yeast genome. Genome Research, 18(7):1073-83

6. Albert I, Wachi S, Jiang C, Pugh BF. (2008) GeneTrack - a genomic data processing and visualization framework. Bioinformatics. 24(10):1305-6

7. Lee C, Li X, Hechmer A, Eisen M, Biggin MD, Venters BJ, Jiang C, Li J, Pugh BF, Gilmour DS. (2008) NELF and GAGA factor are linked to promoter proximal pausing at many genes in Drosophila. Mol Cell Biol.28(10):3290-300

8. Kuo PH, Kalsi G, Prescott CA, Hodgkinson CA, Goldman D, van den Oord EJ, Alexander J, Jiang C, Sullivan PF, Patterson DG, Walsh D, Kendler KS, Riley BP. (2008) Association of ADH and ALDH Genes with Alcohol Dependence in the Irish Affected Sib Pair Study of Alcohol Dependence (IASPSAD) Sample. Alcoholism: Clinical and Experimental Research. 32(5):785-95

9. Zhao, Z and Jiang, C (2007) Methylation-Dependent Transition Rates Are Dependent on Local Sequence Lengths and Genomic Regions. Mol Biol Evol.,24(1):23-5

10. Jiang, C, Han, L, Su, B, Li, WH and Zhao, Z (2007) Features and Trend of Loss of Promoter-Associated CpG Islands in the Human and Mouse Genomes. Mol Biol Evol.24(9):1991-2000

11. Jiang, C, Xuan, Z, Zhao, F, and Zhang, MQ (2007) TRED: a Transcriptional Regulatory Element Database, new entries and other development. Nucleic Acids Res.,35: D137-D140

12. Seo, D, Jiang, C and Zhao, Z (2006) A novel statistical method to estimate the effective SNP size in vertebrate genomes and categorized genomic regions. BMC Genomics,7(1):329

13. Boddu, J, Jiang, C, Sangar, V, Olson, T, Peterson, T, and Chopra, S (2006) Comparative structural and functional characterization of sorghum and maize duplications containing orthologous Myb transcription regulators of 3-deoxyflavonoid biosynthesis. Plant Molecular Biology, 60(2):185-99

14. Jiang, C and Zhao, Z (2006) Directionality of point mutation and 5-methylcytosine deamination rates in the chimpanzee genome. BMC Genomics,7(1):316

15. Jiang, C and Zhao, Z (2006) Mutational spectrum in the recent human genome inferred by single nucleotide polymorphisms. Genomics,88(5):527-34

16. Jiang, C, Gu, X, and Peterson, T (2004) Identification of conserved gene structures and carboxy-terminal motifs in the Myb gene family of Arabidopsis and Oryza sativa L. ssp. indica. Genome Biology, 5(7): R46

17. Jiang, C, Gu, J, Chopra , S, Gu, X, and Peterson, T (2004) Ordered Origin of the Typical Two- and Three-Repeat Myb Genes. Gene, 326: 13-22

18. Jiang, C, Song, WQ, Li, XL, and Chen, RY (1998) Studies on microdissection and microcloning of the rye chromosome 1R. Acta Botanica Sinica, 40(11): 988-993