段新瑞

段新瑞，博士，現任職於陝西師範大學化學化工學院教授。

基本介紹

• 中文名：段新瑞
• 畢業院校：中國科學院化學研究所
• 學位/學歷：博士
• 職業：教師
• 專業方向：幹細胞識別與分離新方法等
• 任職院校：陝西師範大學化學化工學院

個人經歷

2003年7月於河北大學獲理學學士學位；2006 年7月於河北大學獲理學碩士學位；2010年7月於中國科學院化學研究所獲理學博士學位。

2022年9月，晉級為中國化學會高級會員。

研究方向

1. 幹細胞識別與分離新方法；
2. 點擊化學激活的螢光小分子探針；
3. 生物活性靜電紡絲材料。

研究手段：有機合成；點擊化學；磁性分離；代謝標記；靜電紡絲。

學術成果

至今在J. Am. Chem. Soc., Nat. Protoc., Adv. Mater., Anal. Chem., Chem. Commun., 等國際刊物發表文章40餘篇。講授課程：化學分析，儀器分析，現代分析化學（雙語），無機及分析化學，化學生物學。

論文:

2020

1. Yiqian Ren, Yao Qiang, Xinrui Duan* and Zhengping Li*,The distinct difference in azido sugar metabolic rate between neural stem cells and fibroblasts and its application for decontamination of chemically induced neural stem cells,Chemical Communications, 2020, DOI:10.1039/C9CC09362A.(Pdf);

2019

1. Yiqian Ren,Yanru Li, Xinrui Duan*, Honghong Wang, Hui Wang, Zhengping Li*, One‐Step Quantitative Single Nucleotide Polymorphism (SNP) Diagnosis By Modified Loop‐Mediated Isothermal Amplification (mLAMP),ChemistrySelect, 2019, 4, 1423-1427.

2. Zengjin Li, Hui Guo, Fangyuan Xu, Wei Tang*, Xinrui Duan*, Sensitive monitoring of RNA transcription by optical amplifcation of cationic conjugated polymersTalanta, 2019, 203, 314-321.

3.Fangyuan Xu, Mengyue Fan, Saisai Kang, XinruiDuan*,A genetically encoded fluorescent biosensor for detecting nitroreductase activity in living cancer cellsAnalytica Chimica Acta2019, 1088, 131-136.

2018

1. Fangyuan Xu, Wei Tang, Saisai Kang, Jinsheng Song,*Xinrui Duan*,A highly sensitive and photo-stable fluorescent probe for endogenousintracellular H₂O₂imaging in live cancer cellsDyes and Pigments2018, 153, 61-66.

2. Beibei Zhu, Wei Tang, Yiqian Ren, Xinrui Duan*, Chemiluminescence of conjugated-polymer nanoparticles by direct oxidation with hypochlorite,Anal. Chem.2018, 90, 13714-13722.

3. Hui Guo,‡ Mengyue Fan,‡ Zengjin Li, Wei Tang* and Xinrui Duan*, Ratiometric RNA aptamer/fluorophore complex for RNA synthesis detection,Anal. Methods, 2018, 10, 5629-5633.

4. Hui Guo, Wei Tang, Xinrui Duan*, A selective and sensitive azido near-infrared fluorescent probe for tris(2-carboxyethyl) phosphine quantitative detection and its application forE. colidetermination,Anal. Methods, 2018, 10, 5823-5826.

2017

1.Hui Wang, Honghong Wang,Xinrui Duan*, Chenghui Liu, Zhengping Li*,Digital quantitative analysis of microRNA in single cell based on ligationdependedpolymerase colony (Polony),Biosens. Bioelectron. 2017, 95, 146-151.

2.Hui Wang, Honghong Wang,Xinrui Duan*, Xiangdong Wang, Yuanyuan Sun, Zhengping Li*,Sensitive detection of mRNA by using specific cleavage-mediatedisothermal exponential amplification reaction,Sensors and Actuators B,2017, 252, 215-221.

3. Honghong Wang, Hui Wang,Xinrui Duan*,Yuanyuan Sun, Xiangdong Wang, Zhengping Li*,Highly sensitive and multiplexed quantification ofmRNA splice variants by the direct ligation of DNAprobes at the exon junction and universal PCRamplification,Chem. Sci.2017, 8, 3635-3640.

4. Mengyue Fan, Yuanyuan Zhou, Yijing Guo, Jinsheng Song*,Xinrui Duan*,Bright red fluorescent conjugated polymernanoparticles with dibenzopyran as electron donorfor cell imaging,Anal. Methods2017, 9, 3255–3259.

2016

1. Yanru Li, Lingbo Sun, Hongxia Fu,Xinrui Duan*,Facile fabrication of a 3D electrospun fibrous matby ice-templating for a tumor spheroid culture,Polym. Chem.2016, 7, 6805-6811.

2. Lingbo Sun, Hongxia Fu, Yanru Li,Xinrui Duan*; Zhengping Li*, Rapid recognition and isolation of live colon cancer stem cells by using metabolic labeling of azido sugar and magnetic beads,Anal. Chem.2016,88, 3953–3958.

2015

1. Hongxia Fu, Yanru Li, Lingbo Sun, Pan He,Xinrui Duan*,Ratiometric fluorescence azide-alkyne cycloaddition for live mammalian cell imaging,Anal. Chem.2015, 87，11332-11336.

2. Tianyu Wang, Hongxia Fu,Xinrui Duan*and Zhengping Li* An electrospun micro/nanofibrous mesh based nontoxic sensor for optical detection of high humidity,Anal. Methods2015, 7, 3676.

3. Hongxia Fu andXinrui Duan*,Highly sensitive and colorimetric detection of hydrogen sulphide by in situ formation of Ag2S@Ag nanoparticles in polyelectrolyte multilayer filmRSC advances2015, 5, 3508.

2013 & Before:

1.Xinrui Duan, Honglin Li, Hexin Chen*, Qian Wang*, Discrimination of colon cancer stem cells using noncanonical amino acid,Chem. Comm.2012,48, 9035-9037.

2.Xinrui Duan, Libing Liu, Xuli Feng, Shu Wang*, Assemblies of Conjugated Polyelectrolytes with Proteins for Controlled Protein Photoinactivation,Adv. Mater.2010, 22, 1602.

3.Xinrui Duan, Wei Yue, Libing Liu, Zhengping Li, Yuliang Li, Fuchu He, Daoben Zhu, Gangqiao Zhou*, Shu Wang*, Single nucleotide polymorphism (SNP) genotyping using cationic conjugated polymers in homogeneous solution,Nat. Protoc.2009, 4, 984-991.

4.Xinrui Duan, Zhengping Li*, Fang He, Shu Wang*, A sensitive and Homogeneous SNP Detection Using Cationic Conjugated Polymers,J. Am. Chem. Soc.2007, 129, 4154-4155.

榮譽獎勵

2010年度中國科學院院長優秀獎。曾獲得2011年度中國科學院優秀博士學位論文。