楊雲鋒

楊雲鋒

楊雲鋒,清華大學環境學院研究員,環境模擬與污染控制國家重點聯合實驗室研究員。出生地江西吉安。無黨派。廣東省第十三屆人民代表大會代表。

基本介紹

  • 中文名:楊雲鋒
  • 出生地:江西吉安
  • 職業:研究員
  • 性別:男
基本信息,個人簡歷,教育背景,工作履歷,研究領域,科學類,工程類,代表性成果,研究概況,獎勵與榮譽,學術成果,

基本信息

楊雲鋒,清華大學環境學院研究員,環境模擬與污染控制國家重點聯合實驗室研究員。無黨派。
通訊地址:清華大學環境節能樓925室

個人簡歷

教育背景

1996.08 – 2003.01 美國Albert Einstein College of Medicine生物專業,博士
2000.01 – 2002.05 美國City University of New York計算機專業,碩士 (第二學位)
1991.09 – 1996.07 中國科大生物系,學士

工作履歷

2011.01-至今 清華大學環境學院,研究員
2010.09-2011.01 清華大學環境科學與工程系,研究員
2006.03-2010.09 美國橡樹嶺國家實驗室生命科學部,研究員(staff scientist)
2006.08-2009.12 美國DENISON大學,兼職教授(part-time professor)
2003.02-2006.03 美國橡樹嶺國家實驗室環境科學部,博士後

研究領域

科學類

與全球氣候變化相關的環境微生物群落結構、多樣性、功能的解析和調控
生物功能基因網路的構建和解析

工程類

套用環境微生物的油氣礦藏勘探新技術
污水、固廢處理處置的微生物過程研究
生物能源、污染場地生物修復的微生物資源開發和基因工程改造

代表性成果

2003 年在美國愛因斯坦醫學院獲微生物學博士學位後開始進入環境微生物學領域。2003-2010年,在美國橡樹嶺國家實驗室系統開展了可用於污染環境生物清理和生物能源的環境微生物基因組學和基因工程學的研究。在此期間,作為科研項目負責人(PI)領導了一個由博士後、技術員和交換學生組成的實驗室,並任美國能源部生物能源中心微生物基因工程課題負責人。與美國工程院院士James Liao 教授作為聯合團隊共同負責人,製造了世界上第一個纖維素-異丁醇轉化細菌(該類細菌在自然界尚未發現),該項成就於2011 年3 月獲時任美國能源部部長朱棣文的書面肯定,並被白宮網站和數十家國際媒體報導。
2010年9月全職回國,致力於通過基因組學和基因工程技術來研究氣候變化對我國土壤微生物多樣性的影響,建立了以基因組學和基因工程學為主要技術手段,以微生物為研究對象,以關鍵環境問題的基礎科研為特色的研究思路,取得了一系列具有一定創新性和國際影響的研究成果,在The ISME Journal(《自然》出版集團刊物)、Global change biology、Environmental microbiolgoy等期刊發表多篇學術論文。2012 年以來獲國家自然科學基金委面上、重點項目、科技部973、863等項目、住建部水專項等項目資助。2013年獲“清華大學環境學院科研先進個人”榮譽,2014年獲清華大學青年學者最高獎“學術新人獎”。

研究概況

近年主持或者參與主持的科研項目:
1. 城市污水高含固污泥高效厭氧消化裝備開發與工程示範子課題(住建部水專項,2013-2016)
2. 碳循環關鍵過程及其與氣候系統耦合的研究子課題(科技部973項目,2013-2017)
3. 凍土帶天然氣水合物微生物勘查技術子課題(科技部863項目,2012-2015)
4. 環境多因子對溫帶草原土壤微生物群落結構的影響(國家基金委面上項目,2012-2015)
5. 基於宏基因組學技術的工程系統微生物群落特徵研究(國家重點實驗室自主項目,2011-2013)
6.能源部生物能源中心梭菌遺傳工程項目(美國能源部GTL項目, 2007 – 2012)
7. 楊樹–微生物相互作用項目,分離微生物和遺傳工程開發子課題(美國能源部GTL項目2009 – 2012)
8. 土壤微生物分布、轉移過程中細胞膠結的定量分析子課題 (美國能源部ERSP exploratory項目2010 – 2011)
9.對重金屬污染的地下水中分離和篩選功能微生物項目,分離微生物子課題(美國能源部ERSP項目,2007 – 2010)
10. 系統生物學方法理解植物抗旱性機理項目,功能基因組學分析和生物網路構建子課題(美國橡樹嶺國家實驗室LDRD項目,2007 – 2010)
11. 合成氣-醇類轉換細菌的遺傳工程開發(美國橡樹嶺國家實驗室LDRD項目,2007 – 2010)
12. 食品生產過程中檢測沙門氏菌的新型技術(Mars, Inc. 資助項目和美國橡樹嶺國家實驗室Seed money項目2009 – 2010)
13. Shewanella Federation 還原金屬分子機制子課題(美國能源部GTL項目,2006 – 2008)
14. 生物能源梭菌的遺傳工程開發(美國橡樹嶺國家實驗室Seed money項目, 2006 – 2007)

獎勵與榮譽

1.清華大學環境學院科研先進個人(2013)
2. 清華大學"學術新人獎" (2014)
3.2018年8月3日,根據《國家傑出青年科學基金項目管理辦法》的有關規定,國家自然科學基金委員會將2018年度國家傑出青年科學基金建議資助項目申請人名單予以公布,楊雲鋒在名單之中。

學術成果

發表文章
近五年論文引用次數800餘次。
1.M. Zhao, K. Xue, F. Wang, S. Liu, S. Bai, B. Sun, J. Zhou and Y. Yang* (2014), Microbial mediation of biogeochemical cycles revealed by simulation of global changes with soil transplant and cropping, The ISME Journal, doi: 10.1038/ismej.2014.46
2.S Liu, F Wang, K Xue, B Sun, Y Zhang, Z He, JD Van Nostrand, J Zhou, Y Yang* (2014), The interactive effects of soil transplant into colder regions and cropping on soil microbiology and biogeochemistry, Environmental Microbiology, doi:10.1111/1462-2920.12398
3.H Chu, S Wang, H Yue, Q Lin, Y Hu, X Li, J Zhou, Y Yang* (2014), Contrasting soil microbial community functional structures in two major landscapes of the Tibetan alpine meadow, MicrobiologyOpen, accepted
4.Y Gao, S Wang, D Xu, H Yu, L Wu, Q Lin, Y Hu, X Li, Z He, Y Deng, J Zhou, Y Yang* (2014), GeoChip as a Metagenomics Tool to Analyze the Microbial Gene Diversity along an Elevation Gradient, Genomics Data, accepted
5.M Zhao, F Wang, Shanshan Liu, K Xue, Y Liang, S Bai, Z He, JDV Nostrand, J Zhou, Y Yang*, B Sun* (2014), GeoChip profiling of microbial community in response to global changes simulated by soil transplant and cropping, Genomics Data, accepted
6.Y. Sun, Y. Shen, P. Liang, J. Zhou, Y. Yang*, Xia Huang* (2014), The remarkable linkages between microbial functional potentials and wastewater constituents in large-scale operational membrane bioreactors for the municipal wastewater treatment, Water research 56, 162-171
7.Y Yang*, Y Gao, S Wang, D Xu, H Yu, L Wu, Q Lin, Y Hu, X Li, Z He, Y Deng, J Zhou (2014), The microbial gene diversity along an elevation gradient of the Tibetan grassland, The ISME Journal 8 (2), 430-440
8.J. Zhou, Y. Deng, P. Zhang, K. Xue, Y. Liang, JDV Nostrand, Y. Yang, Z. He, L. Wu, D. Stahl, T. Hazen, J. Tiedje, A. Arkin (2014), Stochasticity, succession, and environmental perturbations in a fluidic ecosystem, Proceedings of the National Academy of Sciences 111 (9), E836-E845
9.X Wang, Y Xia, X Wen, Y Yang, J Zhou (2014), Microbial Community Functional Structures in Wastewater Treatment Plants as Characterized by GeoChip, PLoS One 9(3): e93422
10.Y Zhang, J Cong, H Lu, C Yang, Y Yang, J Zhou, D Li (2014), An Integrated Study to Analyze Soil Microbial Community Structure and Metabolic Potential in Two Forest Types, PLoS One 9(4): e93773
11.Y Li, T Xu, T Tschaplinski, N Engle, Y Yang, D Graham, Z He, J Zhou (2014), Improvement of cellulose catabolism in Clostridium cellulolyticum by sporulation abolishment and carbon alleviation, Biotechnology for Biofuels 7 (1), 25
12.Y Xia, X Wang, X Wen, K Ding, J Zhou, Y Yang, Y Zhang (2014), Overall functional gene diversity of microbial communities in three full-scale activated sludge bioreactors, Appl. Microbiol. Biotechnol, accepted.
13.Y Yang*, J Chen, D Qiu, J Zhou (2013), Roles of UndA and MtrC of Shewanella putrefaciens W3-18-1 in iron reduction, BMC microbiology 13 (1), 267
14.X Sun, Y Gao and Y Yang* (2013), Recent advancement in microbial environmental research using metagenomics tools,Biodiversity Science, 21 (4): 393–400
15.Y Yang* (2013), Omics breakthroughs for environmental microbiology, Microbiology China 40 (1), 18-33
16.Y Yang*, L. Wu, Q. Lin, M. Yuan, D. Xu, H. Yu, Y. Hu, J. Duan, X. Li, Z. He, K. Xue, J. Nostrand, S. Wang and J. Zhou (2013), Responses of the functional structure of soil microbial community to livestock grazing in the Tibetan alpine grassland, Global Change Biology 19(2), 637–648
17.D Qiu, H Wei, Q Tu, Y Yang, M Xie, J Chen, MH Pinkerton, Y Liang, Z He, J Zhou (2013) Combined genomics and experimental analyses of respiratory characteristics of Shewanella putrefaciens W3-18-1, Applied and environmental microbiology 79 (17), 5250-5257
18.G Mohr, W Hong, J Zhang, G Cui, Y Yang, Q Cui, Y Liu and AM Lambowitz (2013), A Targetron System for Gene Targeting in Thermophiles and Its Application in Clostridium thermocellum, PloS one 8 (7), e69032
19.J Zhou, Y Jiang, Y Deng, Z Shi, B Zhou, K Xue, L Wu, Z He and Y Yang (2013), Random Sampling Process Leads to Overestimation of β-Diversity of Microbial Communities, mBio 4 (3)
20.J Zhou, W Liu, Y Deng, YH Jiang, K Xue, Z He, JD Van Nostrand, L Wu, Y Yang and A. Wang (2013), Stochastic Assembly Leads to Alternative Communities with Distinct Functions in a Bioreactor Microbial Community, mBio 4 (2)
21.Y Zhang, Z Lu, S Liu, Y Yang, Z He, Z Ren, J Zhou and D Li (2013), Geochip-based analysis of microbial communities in alpine meadow soils in the Qinghai-Tibetan plateau, BMC microbiology 13 (1), 72
22.Y. Deng, Y. Jiang, Y. Yang, Z. He, F. Luo and J. Zhou (2012), Molecular ecological network analyses, BMC Bioinformatics 13:113
23.Y. Li, T. Tschaplinski, N. Engle, C. Hamilton, M. Rodriguez, J. Liao, C. Schadt, A. Guss, Y. Yang and D. Graham (2012), Combined inactivation of the Clostridium cellulolyticum lactate and malate dehydrogenase genes substantially increases ethanol yield from cellulose and switchgrass fermentations, Biotechnology for Biofuels 5:2-2
24.J Lin, J Zuo, R Ji, X Chen, F Liu, K Wang, Y Yang (2012), Methanogenic community dynamics in anaerobic co-digestion of fruit and vegetable waste and food waste, Journal of Environmental Sciences 24 (7), 1288-1294
25.J. Zhou, L. Wu, Y. Deng, X. Zhi, Y. Jiang, Q. Tu, J. Xie, J. D. Van Nostrand, Z. He and Y. Yang (2011), Reproducibility and Quantitation of Amplicon Sequencing-based Detection. The ISME Journal 5: 1303-1313
26.W. Higashide, Y. Li, Y. Yang and J. Liao (2011), Metabolic Engineering of Clostridium cellulolyticum for Production of Isobutanol from Cellulose, Applied and Environmental Microbiology 77(8): 2727-2733
27.J. Zhou, Y. Deng, F. Luo, Z. He and Y. Yang (2011) Phylogenetic Molecular Ecological Network of Soil Microbial Communities in Response to Elevated CO2, mBio 2(4): e00122-11
28.Y. Yang*, L. A. McCue, A. B. Parsons, S. Feng and J. Zhou (2010), The tricarboxylic acid cycle in Shewanella oneidensis is independent of Fur and RyhB control. BMC Microbiology 10:264
29.C. Hemme, Y. Yang, J. Zhou et al., Sequencing of Multiple Clostridial Genomes Related to Biomass Conversion and Biofuel Production (2010). J. Bacteriol. 192(24): 6494-6496
30.H. Gao, S. Barua, Y. Liang, L. Wu, Y. Dong, S. Reed, J. Chen, D. Culley, D. Kennedy, Y. Yang, Z. He, K. Nealson, J. Fredrickson, J. Tiedje, M. Romine, J. Zhou (2010), Impacts of Shewanella oneidensis c-type cytochromes on aerobic and anaerobic respiration, Microbial Biotechnology 3(4): 455-466
31.X. Zhang, Z. Zhang, Z. Zhu, N. Sathitsuksanoh, Y. Yang and P. Zhang (2010), A Highly-Active Family 48 Cellobiohydrolase from Clostridium phytofermentans ISDg: Heterologous Expression in Escherichia coli and Bacillus subtilis, Characterization, and Processivity. Appl. Microbiol. Biotechnol 86(2):525-533
32.Y. Yang*, D. P. Harris, F. Luo, W. Xiong, M. Joachimiak, L. Wu, P. Dehal, J. Jacobsen, Z. Yang, A. V. Palumbo, A. P. Arkin and J. Zhou (2009), Snapshot of Iron Response in Shewanella oneidensis by Gene Network Reconstruction, BMC Genomics 10:131
33.Y. Yang* (2009) Use of Genomic DNA as Reference in DNA Microarrays, Micro and Nano Technologies in Bioanalysis, 439-450
34.Y. Yang*, M. Zhu, L. Wu and J. Zhou (2008) Assessment of Data Processing to Improve Reliability of Microarray Experiments Using Genomic DNA Reference, BMC Genomics 9(S2):S5.
35.Y. Yang*, D. P. Harris, F. Luo, L. Wu, A. B. Parsons, A. V. Palumbo and J. Zhou (2008) Physiological and Transcriptomic Analyses to Characterize the Function of Fur and Iron Response in Shewanella oneidensis, BMC Genomics 9(S1):S11.
36.F. Luo, Y. Yang, J. Zhong, H. Gao, L. Khan, D. K. Thompson and J. Zhou (2007) Constructing Gene Co-expression Networks and Predicting Functions of Unknown Genes by Random Matrix Theory, BMC Bioinformatics 8:299. (co-first author)
37.F. Luo, Y. Yang, C. Chen, R. Chang, J. Zhou and R. Scheuermann (2007) Modular Organization of Protein Interaction Networks, Bioinformatics 23(2):207-214.
38.Y. Yang*, M. Zhu, L Wu, J Zhou (2007) Biostatistical Considerations of the Use of Genomic DNA Reference in Microarrays, Bioinformatics and Bioengineering 7: 593-600
39.M. Zhu, Q. Wu, Y. Yang and J. Zhou (2006) A New Approach to Identify Functional Modules Using Random Matrix Theory, Annual IEEE Symposium on Computational Intelligence in Bioinformatics and Computational Biology 1:117-123.

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