李家柱，男，漢族，1982年4月出生，教授，碩士研究生導師。研究領域主要是功能有機分子設計與合成，主要針對卟啉、葉綠素a、BODIPY及其它含吡咯雜環衍生物進行設計合成，改善其光物理學和電化學性質，以期作為光敏劑套用於腫瘤光動力治療（PDT）、染料敏化太陽能電池（DSSC）、離子識別或超分子組裝等領域研究。
基本介紹
- 中文名：李家柱
- 國籍：中國
- 民族：漢族
- 出生日期：1982年4月
- 性別：男
- 學位/學歷：博士
教育經歷,工作經歷,科研項目,代表論文,獲獎情況,
教育經歷
2000/09–2004/07，煙臺大學，生物技術，理學學士
2004/09–2007/07，煙臺大學，藥物化學，醫學碩士
2007/09–2012/02，Inje University（韓國），納米工學，工學博士
2012/03–2013/02，Yonsei University（韓國），博士後
工作經歷
2013/03–2016/08，煙臺大學，化學化工學院，講師
2016/09–至 今，煙臺大學，化學化工學院，副教授
2016/06–至 今，煙臺大學，化學化工學院，碩士研究生導師
2017/09–至 今，煙臺大學，化學化工學院，有機化學教研室主任
科研項目
（1）基於葉綠素氧化反應的β-取代D-π-A型二氫卟吩光敏染料的設計、合成與光伏性能（山東省自然科學基金），2015.07-2017.07，13.0萬，主持
（2）具有電子給體-π共軛系統-電子受體（D-π-A）結構的新穎葉綠素類二氫卟吩光敏染料的分子設計、合成及其光伏性能研究（教育部留學回國人員科研啟動基金），2015.05，3.5萬，主持
（3）用於直接凝固注模成型工藝的氮化矽粉體表面改性方法與機理研究（國家自然科學基金），2015.01-2018.12，80萬，參與
（4）功能染料、乳液及助劑的研發（企業橫向），2018.10-2020.12，50.0萬，主持
代表論文
（1）Xin Ren, Xiaodong Li, Ze Yang*, Xin Wang, Jianjiang He, Kun Wang, Jungang Yin*,Jiazhu Li*, Changshui Huang*, Tailoring Acetylenic Bonds in Graphdiyne for Advanced Lithium Storage,ACS Sustainable Chem. Eng.,2020, 8(7), 2614−2621.
（2）Zhen Zhang*, Ziqiang Qin, Wenxu Chang,Jiazhu Li*, Ruoqian Fan, Xing Wu, Rongrong Guo, Xiangqi Xie, Lanxin Zhou, Nickel-Catalyzed Decarboxylative Cyclization of Isatoic Anhydrides with Carbodiimides: Synthesis of 2,3-Dihydroquinazolin-4(1H)-ones,Adv. Synth. Catal.,2020, 362, 2864-2869.
（3）Hongwei Wang*,†, Silong Sun*, Wenyang Ge*, Lanfei Zhao*, Bingqian Hou*, Kai Wang*, Zhongfan Lyu*, Liyang Chen, Shoushen Xu, Jun Guo, Min Li, Peisen Su, Xuefeng Li, Guiping Wang, Cunyao Bo, Xiaojian Fang, Wenwen Zhuang, Xinxin Cheng, Jianwen Wu, Luhao Dong, Wuying Chen, Wen Li, Guilian Xiao, Jinxiao Zhao, Yongchao Hao, Ying Xu, Yu Gao, Wenjing Liu, Yanhe Liu, Huayan Yin,Jiazhu Li, Xiang Li, Yan Zhao, Xiaoqian Wang, Fei Ni, Xin Ma, Anfei Li, Steven S. Xu, Guihua Bai, Eviatar Nevo, Caixia Gao, Herbert Ohm, Lingrang Kong†, Horizontal gene transfer of Fhb7 from fungus underlies Fusarium head blight resistance in wheat,Science,2020, 368, 844.
（4）Jian Wang, Xiangmin Wang, Zhong Zheng, Jihua Ma, Xu Wang, Woo Kyoung Lee, Young Key Shim, Il Yoon*, Jinchun Chen*,Jiazhu Li*, Efficient Metal-Free Synthesis of Dihydro[1,3]oxazines Assisted by Intramolecular Hydrogen Bonding,Bull. Korean Chem. Soc.,2020, 41(9), 884–887.
（5）Huiqiang Wu, Xiangmin Wang, Yang Liu, Yu Zhao, Xinyue Wang, Woo Kyoung Lee, Young Key Shim, Il Yoon*, Xinming Xu*, andJiazhu Li*, Efficient Synthesis of Long-wavelength Absorbing Cyanochlorophyll a Derivatives via Stereoselective Horner–Wadsworth–Emmons Reaction,Bull. Korean Chem. Soc.,2020, 41(5), 504-512.
（6）Yang Liu, Huiqiang Wu, Xiao Zhang, Qiang Pan, Xiangmin Wang, Wei Peng, Jungang Yin, Guizhi Li*,Jiazhu Li*, Jinjun Wang*, Regioselective reactions of methyl pyropheophorbide a with formaldehyde based on hydroxymethylation,Chem. Pap.,2018, 72, 1389-1398.
（7）Jiazhu Li*, Nailiang He, Yang Liu, Ziping Zhang, Xiao Zhang, Xueying Han, Yunyun Gai, Yongming Liu, Jungang Yin* and Jinjun Wang*, Synthesis and photophysical properties of novel pyridine fused chlorophyll a derivatives,Dyes Pigments,2017, 146, 189-198.
（8）Na Gao,Jia-Zhu Li*, Yan-Long Li, Zhen Wang, Jin-Jun Wang*, A facile synthesis of cyano-chlorins related to chlorophyll from formyl (pyro)-pheophorbide-a by a tandem transformation of the aldehyde into a nitrile group,Chin. Chem. Lett.,2016, 27(5): 789-794.
（9）Jiazhu Li, Yang Liu, Xi-Sen Xu, Yan-Long Li, Shan-Guo Zhang, Il Yoon, Young Key Shim, Jin-Jun Wang* and Jun-Gang Yin*, Highly efficient synthesis of novel methyl 13-methylene mesopyropheophorbide a and its stereoselective Michael addition reaction,Org. Biomol. Chem.,2015, 13(7): 1992-1995.
（10）Jiazhu Li*, Xin Zhang, Yang Liu, Il Yoon, Dong-Kyoo Kim, Jun-Gang Yin, Jin-Jun Wang, Young Key Shim*, Synthesis, optical properties and preliminary in vitro photodynamic effect of pyridyl and quinoxalyl substituted chlorins,Bioorg. Med. Chem.,2015, 23(8):1684-1690.
（11）Jiazhu Li, Peng Zhang, Nan-Nan Yao, Li-Li Zhao, Jin-Jun Wang*, Young Key Shim*, Convenient peripheral aroyloxylation reactions of porphyrins and chlorophyll-a-based chlorins with benzoyl peroxide,Tetrahedron Lett., 2014, 55(5): 1086-1089.
（12）Il Yoon, Dorjnamjin Demberelnyamba,Jia Zhu Li, Young Key Shim, Ionic Liquid-Based Chlorins and Type III Mechanism of Photodynamic Therapy (PDT), inHandbooks of Porphyrin Science, eds. Karl M. Kadish, Kevin M. Smith and Roger Guilard, World Scientific Publishing Co. Pte. Ltd., Singapore,2014, Vol. 33, pp. 167-224. (Invited Chapter)
（13）Sudip Kumar Ghosh, Masatoshi Ishida,Jiazhu Li, Won-Young Cha, Vincent Lynch, Dongho Kim*, Jonathan L. Sessler*, Synthesis and anion binding studies of o-phenylene- vinylene-bridged tetrapyrrolic macrocycle as an expanded analogue of calix[4]pyrrole,Chem. Commun.,2014, 50: 3753-3756.
（14）Il Yoon, Jung Hwa Kim,Jia Zhu Li, Woo Kyoung Lee*, Young Key Shim*, Efficient photosensitization by a chlorin-polyoxometalate supramolecular complex,Inorg. Chem.,2014, 53(1): 3-5.
（15）IL Yoon,Jia Zhu Li, Young Key Shim*, Advance in Photosensitizers and Light Delivery for Photodynamic Therapy,Clin. Endosc.,2013, 46: 7-23.
（16）Jia Zhu Li, Jin Jun Wang, Il Yoon, Bing Cun Cui, Young Key Shim*, Synthesis of novel long wavelength cationic chlorins via stereoselective aldol-like condensation,Bioorg. Med. Chem. Lett.,2012, 22: 1846-1849.
（17）Jia Zhu Li, Li Li, Jung Hwa Kim, Bing Cun Cui, Jin Jun Wang and Young Key Shim*, Efficient synthesis and in vitro photodynamic anticancer study of new purpurinimide- hydrazone conjugates.J. Porphyr. Phthalocyan.,2011, 15(4): 264-270.
（18）Jia Zhu Li, Bing Cun Cui, Jin Jun Wang and Young Key Shim*, Aldol-like carbon-carbon condensation for pyridyl substituted chlorins.Bull. Korean Chem. Soc., 2011, 32(7): 2465-2468.
（19）李家柱,劉萬卉,李付國,王進軍,索有瑞,劉永軍*,氫氧化鋰存在下(焦)脫鎂葉綠酸-a甲酯的空氣重排反應,有機化學,2007, 27(12): 1594-1599.
獲獎情況
（1）煙臺大學第七屆青年教師教學競賽一等獎，2017
（2）第一屆“煙臺大學教學質量獎”，2017
（3）第二屆“煙臺大學教學質量獎”，2018
（4）2019年煙臺大學優秀本科畢業論文指導教師
（5）2020年煙臺大學優秀本科畢業論文指導教師
