於斐(鄭州大學副教授)

於斐，女，1977年出生，公共衛生學院副教授、碩士生導師。研究方向：食品衛生檢驗、生物分子識別和檢測，主要從事食品中營養物質、有害物質等高通量檢測和風險評估；疾病生物標誌物識別與檢測。鄭大大學青年骨幹教師， 鄭州大學“三育人”先進個人；兼任河南省預防醫學會衛生檢測檢驗專業委員會委員，河南省營養學會會員。

基本介紹

• 中文名：於斐

基本介紹

於斐，女，1977年出生，公共衛生學院副教授、碩士生導師。鄭大大學青年骨幹教師， 鄭州大學“三育人”先進個人；主持河南省教學研究示範課程項目，主持鄭州大學 “課程思政”教育教學改革試點課程重點項目。獲得河南省自然科學優秀學術論文二等獎5項。獲得河南省教育廳科技進步二等獎1項；兼任河南省預防醫學會衛生檢測檢驗專業委員會委員，河南省營養學會會員。

教育/工作經歷

工作經歷

[1] 2019-2020，Washington State University，Voiland School of Chemical Engineering & Bioengineering 訪問學者

[2] 2017-至今， 鄭州大學，公共衛生學院，副教授

[3] 2007-2016，鄭州大學， 公共衛生學院，講師

[4] 2004-2006，鄭州大學，公共衛生學院，助教

教育經歷

[1] 2012-2016，鄭州大學，公共衛生學院流行病與衛生統計學專業，博士

[2] 2001-2004，鄭州大學，鄭州大學化學系分析化學專業，碩士

[3] 1997-2001，鄭州大學，鄭州大學化學系精細化工專業，本科

主持科研項目

[1] 國家自然科學基金青年基金項目（編號：81402721；年限：2014-2017）：新型磁蛋白納米微粒標記技術的化學發光酶聯免疫法檢測血清中DNA甲基化轉移酶1。

[2] 河南省科技重點研發與推廣項目（科技攻關）項目（編號：202102310140；年限：2020-2021）：重要肺癌標誌物—DNA甲基化關鍵酶DNMT1活性與水平同步檢測方法的構建及套用研究。

[3] 河南省教育廳科學技術研究重點項目（編號：14A330008，年限：2014-2016），一種新型的磁酶免疫增強化學發光分析技術研究。

[4] 鄭州大學青年教師基礎研究培育基金（編號：JC21838047，年限：2020-2021），基於自組裝核酸探針信號放大及免疫雜交技術同步檢測DNA甲基化轉移酶1水平和活性體系的構建及套用研究。

代表性成果

論文

[1] Lulu Song, Tiantian Ma, Fangfang Gong, Leiliang He, Yilin Wang, Qiongwen Zhang, Shuying Zhang, Yongjun Wu, Li-e Liu, Fei Yu*. A high sensitivity strategy of DNMT1 activity detection based on self-assembled nucleic acid probe signal amplification technique. Sensors and Actuators B: Chemical,2023, 385: 133610.

[2] Mimi Zhang, Fei Yu*, Yuan Xue, Lulu Song, Mengsi Du, Xing Li * and Wenjie Li. The Relationship of 25(OH)D3 with Diabetes Mellitus and the Mediation Effect of Lipid Profile in Chinese Rural Population of Henan Province. Medicina Lithunaia. 2022, 58(1): 85.

[3] Zhenzhen Wan, Fangfang Gong, Mimi Zhang, Leiliang He, Yilin Wang, Songcheng Yu, Jie Liu, Yuming Wu, Li’e Liu, Yongjun Wu, Lingbo Qu , Jiaqi Sun, Fei Yu*. Detection of the level of DNMT1 based on self-assembled probe signal amplification technique in plasma. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy，2021, 261:120020.

[4] He ST, He LL, Liu BB, Yu SC, Liu L, Tian YM, Wang J, Ding LH, Wang YL, Qu LB, Yu F*, Wu YJ*. Development of a rapid and sensitivity magnetic chemiluminescence immunoassay for DNA methyltransferase 1 in human serum. CHINESE CHEMICAL LETTERS, 2019, 30(5):1031-1034.

[5] Fei Yu, Yamin Xiong, Songcheng Yu, Leiliang He, Shanshan Niu, Yuming Wu, Jie Liu, Lingbo Qu, Li-e Liu, Yong-jun Wu. Magnetic immunoassay using CdSe/ZnS quantum dots as fluorescent probes to detect the level of DNA methyltransferase 1 in human serum sample. International Journal of Nanomedicine. 2018, 13: 429–437.

[6] Fei Yu, ChongJian Wang, Ling Wang, HongLin Jiang, Yue Ba, LingLing Cui, Yan Wang, SongCheng Yu and WenJie Li. Study and evaluation the impact of VDR variants on the risk of T2DM in Han Chinese. Journal of Diabetes. 2017, 9(3): 275–284.

[7] Fei Yu, Lingling Cui, Xing Li, et al. The genetic polymorphisms in vitamin D receptor and the risk of type 2 diabetes mellitus: an updated meta-analysis. Asia pacific Journal of Clinical Nutrition. 2016, 25(3): 614-624.

[8] Fei Yu, Songcheng Yu, Lanlan Yu，et al. Determination of residual enrofloxacin in food samples by a sensitive method of chemiluminescence enzyme immunoassay. 2014, Food Chemistry, 149: 71-75.

[9] Fei Yu，Yongjun Wu, Songcheng Yu, et al. A competitive chemiluminescence enzyme immunoassay for rapid and sensitive determination of enrofloxacin. 2012, Spectrochimica Acta Part A, 93: 164-168.

[10] Songcheng Yu, Fei Yu, Yaping Li, et al. Magnetic nanoparticles replacing microplate as immobile phase could greatly improve the sensitivity of chemiluminescence enzymatic immunoassay for deoxynivalenol. 2016, Food Control. 60: 500-504.

[11] Songcheng Yu, Fei Yu, Hongquan Zhang, et al. Optimization of condition for conjugation of enrofloxacin to enzymes in chemiluminescence enzyme immunoassay. Spectrochimica Acta Part A, 2014, 93: 47-51.

[12] Liang Yan-li, Yu Fei, YuSong-cheng , et al. Effect of the luminol signal enhancer on the chemiluminescence intensity and kinetics. 2012, Journal of Luminescence, 132: 1021–1024.

[13] Songcheng Yu, Fei Yu, Li-e Liu, Hongquan Zhang, Zhenzhong Zhang, Lingbo Qu and Yongjun Wu. Which one of the two common reporter systems is more suitable for chemiluminescent enzyme immunoassay: alkaline phosphatase or horseradish peroxidase? Luminescence, 2015, 31(3): 888-892.

[14] Li-E Liu, Fei Yu, Jindun Liu, Xiuli Han, Haoqin Zhang and Bing Zhang. Removal of Auramine O from Aqueous Solution Using Sesame Leaf: Adsorption Isotherm and Kinetic Studies. Asian Journal of Chemistry, 2013, 25(4): 1991-1998.

[15] Yan Wang, Fei Yu, Songcheng Yu, Dongdong Zhang, Jun Wang, Han Han, Hualei Sun,Yuan Xue, Yue Ba, Chongjian Wang, Wenjie Li. Triangular relationship between CYP2R1 gene polymorphism, serum25(OH)D3 levels and T2DM in a Chinese rural population. Gene. 2018: 678:172-176.