基本介紹
- 中文名：戴兆來
- 學位/學歷：博士
- 職業：教師
- 專業方向：腸道及腸道微生物的營養生化
- 任職院校：中國農業大學
個人經歷,研究方向,學術成果,榮譽獎項,
個人經歷
學與工作經歷：
2015. 1 –至今
副研究員，動物營養生化實驗室，動物營養國家重點實驗室，中國農業大學動物科技學院
2013. 4 – 2014. 12
助理研究員，動物營養生化實驗室，動物營養國家重點實驗室，中國農業大學動物科技學院
2011. 3 – 2013. 4
博士後，導師：伍國耀教授，動物營養生化實驗室，動物營養國家重點實驗室，中國農業大學動物科技學院
2009. 2 – 2010. 2
國家公派，聯合培養博士生項目，合作導師：伍國耀教授，美國德州農工大學，動物科學系（Department of Animal Science, Texas A&M University）
2007. 9 – 2010. 12
博士，導師：朱偉雲教授，消化道微生物研究室，南京農業大學動物科技學院
2005. 9 – 2007. 7
碩士，導師：朱偉雲教授，消化道微生物研究室，南京農業大學動物科技學院
2001. 9 – 2005. 7
本科，動物科學專業，南京農業大學動物科技學院
研究方向
腸道及腸道微生物的營養生化
學術成果
承擔科研項目：
1. 國家重點基礎研究發展計畫（973計畫）“豬利用氮營養素的機制及營養調控”子課題：“腸道微生物與氮營養素的消化代謝”（2013CB127303），子課題骨幹，經費待撥，2015-2017
2. 國家自然科學基金青年基金：“豬腸道色氨酸利用菌調節小腸代謝色氨酸的規律及機制研究”（31301979），主持，23萬元，2014-2016
3.中國農業大學青年教師基本科研業務費：“不同蛋白源對豬腸道微生物區系及代謝胺基酸的影響及機制研究”（2014XJ001），主持，10萬元，2014-2016
4.中國博士後科學基金第五批特別資助：“細菌對小腸黏膜轉運及代謝必需胺基酸的影響及機制研究”（2012T50163），主持，15萬元，2012，結題
5.中國農業大學博士後科研創新項目：“豬小腸細菌對菜籽粕分解代謝的初步研究”（2011BH001），主持，1萬元，2011，結題
發表文章：
1.Zhaolai Dai, Zhenlong Wu, Suqin Hang, Weiyun Zhu, Guoyao Wu. Amino acid metabolism in intestinal bacteria and its potential implications for mammalian reproduction. Mol Hum Reprod. 2015, 21(5):389-409.
2.Zhaolai Dai, Zhenlong Wu, Sichao Jia, Guoyao Wu. Analysis of amino acid composition in proteins of animal tissues and foods as pre-column o-phthaldialdehyde derivatives by HPLC with fluorescence detection. J Chromatogr B Analyt Technol Biomed Life Sci. 2014, 964:116-27
3.Zhaolai Dai, Zhenlong Wu, Junjun Wang, Xiaoqiu Wang, Sichao Jia, Fuller W Bazer, Guoyao Wu. Analysis of polyamines in biological samples by HPLC involving pre-column derivatization with o-phthalaldehyde and N-acetyl-L-cysteine. Amino Acids. 2014, 46(6):1557-64
4.Zhaolai Dai, Zhenlong Wu, Ying Yang, Junjun Wang, M Carey Satterfield, Cynthia J Meininger, Fuller W Bazer, Guoyao Wu. Nitric oxide and energy metabolism in mammals. Biofactors. 2013, 39(4):383-91
5.Zhao-Lai Dai, Xi-Long Li, Peng-Bin Xi, Jing Zhang, Guoyao Wu, Wei-Yun Zhu. L-Glutamine regulates amino acid utilization by intestinal bacteria. Amino Acids. 2013, 45(3):501-12
6.Zhao-Lai Dai, Xi-Long Li, Peng-Bin Xi, Jing Zhang, Guoyao Wu, Wei-Yun Zhu. Regulatory role for L-arginine in the utilization of amino acids by pig small-intestinal bacteria. Amino Acids. 2012, 43(1):233-44
7.Zhao-Lai Dai, Xi-Long Li, Peng-Bin Xi, Jing Zhang, Guoyao Wu, Wei-Yun Zhu. Metabolism of select amino acids in bacteria from the pig small intestine. Amino Acids. 2012, 42(5):1597-608
8.Zhao-Lai Dai, Guoyao Wu, Wei-Yun Zhu. Amino acid metabolism in intestinal bacteria: links between gut ecology and host health. Front Biosci.2011, 16:1768-1786
9.Zhao-Lai Dai, Jing Zhang, Guoyao Wu, Wei-Yun Zhu. Utilization of amino acids by bacteria from the pig small intestine. Amino Acids. 2010, 39:1201–1215
10.Hao Wang, Chen Zhang, Guoyao Wu, Yuli Sun, Bin Wang, Beibei He,Zhaolai Dai, Zhenlong Wu. Glutamine enhances tight junction protein expression and modulates corticotropin-releasing factor signaling in the jejunum of weanling piglets. J Nutr. 2015, 145(1):25-31.
11.Weiwei Wang, Zhenlong Wu, Gang Lin, Sendi Hu, Bin Wang,Zhaolai Dai, Guoyao Wu. Glycine stimulates protein synthesis and inhibits oxidative stress in pig small intestinal epithelial cells. J Nutr. 2014, 144(10):1540-8.
12.Yu-xiang Yang,Zhao-lai Dai, Wei-yun Zhu. Important impacts of intestinal bacteria on utilization of dietary amino acids in pigs. Amino Acids. 2014, 46(11):2489-501
13.Weiwei Wang,Zhaolai Dai, Zhenlong Wu, Gang Lin, Sichao Jia, Shengdi Hu, Sudath Dahanayaka, Guoyao Wu. Glycine is a nutritionally essential amino acid for maximal growth of milk-fed young pigs. Amino Acids. 2014, 46(8):2037-45.
14.Yurui Zhang,Zhaolai Dai, Guoyao Wu, Ran Zhang, Yunping Dai, Ning Li. Expression of threonine-biosynthetic genes in mammalian cells and transgenic mice. Amino Acids. 2014, 46(9):2177-88.
15.Chen Yin, Li Defa,Dai Zhaolai, Piao Xiangshu, Wu Zhenlong, Wang Bin, Zhu Yuhua, Zeng Zhikai. l-Methionine supplementation maintains the integrity and barrier function of the small-intestinal mucosa in post-weaning piglets. Amino Acids. 2014, 46(4):1131-42
16.Li X, Bazer FW, Johnson GA, Burghardt RC, Frank JW,Dai Z, Wang J, Wu Z, Shinzato I, Wu G. Dietary supplementation with L-arginine between days 14 and 25 of gestation enhances embryonic development and survival in gilts. Amino Acids. 2014, 46(2):375-84
17.Guoyao Wu, Fuller W. Bazer,Zhaolai Dai, Defa Li, JunjunWang, Zhenlong Wu. Amino acid nutrition in animals: protein synthesis and beyond. Annu Rev Anim Biosci. 2014, 2:387–417
18.Wu G, Bazer FW, Satterfield MC, Li X, Wang X, Johnson GA, Burghardt RC,Dai Z, Wang J, Wu Z. Impacts of arginine nutrition on embryonic and fetal development in mammals. Amino Acids. 2013, 45(2):241-56.
19.Wang W, Wu Z,Dai Z, Yang Y, Wang J, Wu G.Glycine metabolism in animals and humans: implications for nutrition and health. Amino Acids. 2013, 45(3):463-77.
20.Guoyao Wu, Zhenlong Wu,Zhaolai Dai, Ying Yang, Weiwei Wang, Chuang Liu, Bin Wang, Junjun Wang, Yulong Yin. Dietary requirements of “nutritionally non-essential amino acids” by animals and humans. Amino Acids. 2013, 44(4):1107-1113
21.Gang Lin, Chuang Liu, Cuiping Feng, Zhiyong Fan,Zhaolai Dai, Changhua Lai, Zhen Li, Guoyao Wu, Junjun Wang. Metabolomic analysis reveals differences in umbilical vein plasma metabolites between normal and growth-restricted fetal pigs during late gestation. J Nutr. 2012, 142(6):990-8
22.Pengbin Xi, Zongyong Jiang,Zhaolai Dai, Xilong Li, Kang Yao, Chuntian Zheng, Yingcai Lin, Junjun Wang, Guoyao Wu. Regulation of protein turnover by l-glutamine in porcine intestinal epithelial cells. J Nutr Biochem. 2012, 23(8):1012-7
榮譽獎項
2013年全國優秀博士學位論文提名論文：《豬小腸微生物胺基酸代謝的生態學分析》（作者：戴兆來，指導教師：朱偉雲）
