男，博士，清華大學副研究員，1993-1997年武漢大學生命科學學院，生物化學學士，1997-2000年湖北省醫藥工業研究所，藥理學研究實習員；2000-2006年中國科學院生物物理研究所，生物物理學博士；2006-2010年普林斯頓大學，分子生物學系博士後；2010-至今清華大學醫學院副研究員。
基本介紹
- 中文名：嚴漢池
- 畢業院校：武漢大學
- 研究方向：膜蛋白結構生物學
- 職稱：副研究員
研究方向,發表論文,
研究方向
膜蛋白結構生物學，運姜乎犁紋用以簽煮訂只X-射線晶體學為主的結講催催構生物學手段結合生民朽甩物化轎煉學、生物物理學等其它方法研究與生命活動或疾病發生相關的重要膜蛋白的結構與功能; 藥物研發宙局埋相關的藥理學及毒理學鍵協樂研究。
發表論文
1. Feng L1, Yan H1, Wu Z1, Yan N, Wang Z, Jeffrey PD, Shi Y. Structure of a Site-2 Protease Family Intramembrane Metalloprotease Science. 2007; 318:1608-12. (1 equal contributions)
2. Wu Z, Yan N, Feng L, Oberstein A, Yan H, Baker RP, Gu L, Jeffrey PD, Urban S& Shi Y. Structural analysis of a rhomboid family intramembrane protease reveals a gating mechanism for substrate entry. Nat Struct Mol Biol. 2006; 13:1084-91.
3. Yan H1, Zhang P1, Wang C, Liu Z, and Chang W. Two lutein molecules in LHCII have different conformations and functions: Insights into the molecular mechanism of thermal dissipation in plants. Biochem Biophys Res Commun. 2007; 355:457-463. (1 equal contributions)
4. Liu Z, Yan H, Wang K, Kuang T, Zhang J, Gui L, An X & Chang W. Crystal structure of spinach major light-harvesting complex at 2.72 Å resolution. Nature. 2004; 428:287-292. (Highlighted Cover-Story Article)
5. Pan J, Li J, Qiu Y, Ling S, Yan H. Experimental Study on Pharmacodynamical of Zhitongan Xunxiji. Lishizhen Medicine And Materia Medica Research. 2006; 17(7):1163-1165.
6. Pan J, Li J, Qiu Y, Yan H, Ling S. The safety evaluation of erythromycin stinoprate. Chinese Journal of New Drugs. 2006; 15 (4):276-280.
7. Pan J, Li J, Qiu Y, Yan H, Ling S. A Toxicological Study of Doxepin Hydrochloride Cream in Animals. Herald of Medicine. 2006; 25(2):99-101.
8. Pan J, Li J, Qiu Y, Yan H, Ling S. Acute Toxicity Study of Erythromycin Propionate-N-acetylcysteinate. Journal of Mathematical Medicine. 2006; 19(2):176-177.
9. Pan J, Li J, Qiu Y, Yan H, Ling S. Study on the Teratogenicity of Erythromycin Propionate-N-Acetylcysteinate in Rats. Carcinogenesis, Teratogenesis and Mutagenesis. 2006; 18(1): 32-34.
10. Pan J, Li J, Qiu Y, Yan H, Ling S. The anti-itching and anti-hypersensitivity effects of Doxepin hydrochloride cream. Chinese Pharmacological Bulletin. 2005; 21(12):1505-1508.
11. Pan J, Li J, Qiu Y, Yan H, Ling S. Long-term toxicity of Doxepin Hydrochloride Cream in rabbits. Practical Journal of Medicine & Pharmacy. 2005; 22(10):904-906.
12. Pan J, Li J, Qiu Y, Yan H, Ling S. Long-term toxicity of erythromycin propionate-N-acetylcysteinate in rats. Chinese Journal of New Drugs. 2005; 14 (9):1133-1135.
13. Qiu Y, Cao J, Wang D, Yan H, Ling S, Zhou S, Xu Q. Tissue Residues of Sarafloxacin Hydrochloride in Broiler Chickens. Chinese Journal of Veterinary Science. 2005; 21:515-518.
14. Qiu Y, Wang D, Zhou S, Cao J, Cai Q, Li T, Wang X, Zhou Z, Yan H, Ling S. Comparative Pharmacokinetics of Metabolite of Albendazole Oxide and Albendazole in Sheep Body. Journal of Huazhong Agricultural University. 2000; 19:461-464.
15.Cao J, Qiu Y, Wang D, Zhou L, Zhou S, Xu Q, Yan H, Jiang M. Pharmacokinetics of sarafloxacin hydrochloride in chickens after intravenous and oral administration. Journal of Huazhong Agricultural University. 1999; 18:248-251.
7. Pan J, Li J, Qiu Y, Yan H, Ling S. A Toxicological Study of Doxepin Hydrochloride Cream in Animals. Herald of Medicine. 2006; 25(2):99-101.
8. Pan J, Li J, Qiu Y, Yan H, Ling S. Acute Toxicity Study of Erythromycin Propionate-N-acetylcysteinate. Journal of Mathematical Medicine. 2006; 19(2):176-177.
9. Pan J, Li J, Qiu Y, Yan H, Ling S. Study on the Teratogenicity of Erythromycin Propionate-N-Acetylcysteinate in Rats. Carcinogenesis, Teratogenesis and Mutagenesis. 2006; 18(1): 32-34.
10. Pan J, Li J, Qiu Y, Yan H, Ling S. The anti-itching and anti-hypersensitivity effects of Doxepin hydrochloride cream. Chinese Pharmacological Bulletin. 2005; 21(12):1505-1508.
11. Pan J, Li J, Qiu Y, Yan H, Ling S. Long-term toxicity of Doxepin Hydrochloride Cream in rabbits. Practical Journal of Medicine & Pharmacy. 2005; 22(10):904-906.
12. Pan J, Li J, Qiu Y, Yan H, Ling S. Long-term toxicity of erythromycin propionate-N-acetylcysteinate in rats. Chinese Journal of New Drugs. 2005; 14 (9):1133-1135.
13. Qiu Y, Cao J, Wang D, Yan H, Ling S, Zhou S, Xu Q. Tissue Residues of Sarafloxacin Hydrochloride in Broiler Chickens. Chinese Journal of Veterinary Science. 2005; 21:515-518.
14. Qiu Y, Wang D, Zhou S, Cao J, Cai Q, Li T, Wang X, Zhou Z, Yan H, Ling S. Comparative Pharmacokinetics of Metabolite of Albendazole Oxide and Albendazole in Sheep Body. Journal of Huazhong Agricultural University. 2000; 19:461-464.
15.Cao J, Qiu Y, Wang D, Zhou L, Zhou S, Xu Q, Yan H, Jiang M. Pharmacokinetics of sarafloxacin hydrochloride in chickens after intravenous and oral administration. Journal of Huazhong Agricultural University. 1999; 18:248-251.
