周永昌(香港乳腺癌專家)

周永昌(香港乳腺癌專家)

周永昌,香港乳腺癌專家。

基本介紹

  • 中文名:周永昌
  • 外文名:Louis Wing-Cheong Chow
  • 國籍:中國
  • 性別:男
人物經歷,學習經歷,工作簡歷,主要貢獻,獲獎記錄,

人物經歷

學習經歷

1984年5月M.B.B.S(香港大學)。
1999年12月M.S. (香港大學)。
1984年畢業於香港大學醫學院,其後到美國紐約斯隆凱特琳紀念癌症中心、耶魯大學和南加州大學深造。回 港後,任職於香港大學外科學系,並在港大取得外科學臨床碩士。

工作簡歷

1995年到2005年:香港大學乳腺外科主任
1997年到2005年:香港大學副教授。
1999年到2000年:亞洲乳癌協會主席
2000年到2001年:香港大學醫學院副院長
2000年:成立港大內首間孫志新中醫藥實驗室,並擔任主任一職。
2001年:與現任香港特別行政區食物與衛生局局長高永文醫生等人創立香港中西醫結合會
2001年到2005年:香港東華醫院外科部-洪祖杭乳腺中心主任
2003年:邀請世界各地專家在香港創立“癌轉譯研究組織(00TR)”,擔任行政總監,主要致力於乳腺癌分子治療方法、乳腺癌抗藥性的機制、化學、內分泌和重要的預防方法之研究。至今,癌轉譯研究組織(OOTR)仍然不斷的在乳腺癌治療手段與新藥的使用上開拓非常前沿的臨床試驗和轉化研究。
2005年:周永昌教授成立仁康醫療乳腺綜合診治中心(UNIMED)。仁康擁有多位經驗豐富的醫護專才,並累積多年乳腺疾病治理經驗,配合先進設備,為病人提供更全面的專業服務。醫護團隊方面包括:婦科、內外專科、整形外科、物理治療及科研部門,設有數碼乳房造影檢查、立體定位組織抽取檢查及骨質密度測試等。仁康醫療無復能針對個別病況以進行藥物及術前治療,提供全面的專業諮詢及治療後的富康跟進服務,不論生理或心理上都可得到周全的照顧。
職稱
癌轉譯研究組織(OOTR)執行總監
周永昌
香港仁康醫療乳腺綜合診治中心醫務總監
香港聖德肋撒醫院乳腺診斷治療中心總監
日本東北大學名譽教授
澳門科技大學特聘教授
澳門鏡湖醫院顧問醫生
第三軍醫大學西南醫院客座教授
寧夏醫科大學名譽教授
江西南昌三院客座教授
前任香港醫學專科學院名譽教授、亞洲乳癌協會主席、香港大學李嘉誠醫學院名譽臨床教授

主要貢獻

周永昌教授在擔任香港大學醫療中心乳腺外科主任和香港華東醫院外科部-洪祖杭乳腺中心主任其間,成功引進乳癌微創檢查和切除技術,用於治療兩院的乳腺癌病人;他還把前哨淋巴結組織活檢技術引入香港醫療界,用作診斷乳腺癌在體內轉移的情況;同時,他首次把該技術轉移到豬身體上,用作教導香港各大醫院的主任級醫生,成功開辦兩次學習班,為前哨淋巴結組織活檢技術用於香港乳腺癌病人奠定了堅實的基礎。另外, 他還把人類乳腺葉狀囊肉瘤植入裸鼠體內,並成功分離和培養出細胞株。
周永昌教授在擔任香港大學醫學院副院長期間,與學校同仁把美國哈弗大學的“問題導向學習”(Problem-based learning)的方法經改良後套用於港大醫學院,使得醫學院學生更能靈活學習艱澀的醫學知識,至今香港大學全部都採用此方法教學。
除了在臨床及教學上的工作,他還曾擔任外科學系的教育和訓練中心副主任,並出任多項外科院士考試和博士生的考官。
由於卓越的研究經驗,他的研究項目獲得香港大學和香港政府的多項研究經費,並獲聘於數個國際臨床研究中心的首席研究員。發表學術論為140餘篇。
2010年之後文章發表
The Breast Cancer Working Group presentation was divided into three sections: the epidemiology, pathology and treatment of breast cancer
Toi M, Ohashi Y, Seow A, Moriya T, Tse G, Sasano H, Park BW, Chow LW, Laudico AV, Yip CH, Ueno E, Ishiguro H, Bando H. Jpn J Clin Oncol. 2010 Sep;40 Suppl 1:i13-18...[10-12-31]
國際乳腺癌臨床研究現狀及展望
葉潤燊, 周永昌. 2010第六屆全國乳腺癌重慶論壇論文集, pages 5-9...[10-12-31]
Epigenetic change in E-cadherin and COX-2 to predict chronic periodontitis
Loo WT, Jin L, Cheung MN, Wang M, Chow LW. J Trans Med. 2010; Nov 4;8:110 ...[10-11-4]
Curcumin potentiates the pro-apoptotic effects of sulindac sulfone in colorectal cancer
Giladi N , Kazanov D, Shpitz B, Aroch I, Kraus S and Arber N. Expert Opin Investig Drugs. Apr 2010;19 Suppl 1: S117-124...[10-4-30]
Pharmacogenetics in breast cancer: focus on hormone therapy, taxanes, trastuzumab and bevacizumab
Longo R , D'Andrea M, Sarmiento R and Gasparini G. Expert Opin Investig Drugs. Apr 2010;19 Suppl 1: S41-50...[10-4-30]
Combination of radiological and biochemical methods to assess bone mineral density of mandible in fully edentulous patients after chemotherapy: a 5-year prospective study
Loo WTY , Jin LJ, Cheung MNB, Chow LWC, Wang M. Expert Opin Investig Drugs. Apr 2010;19 Suppl 1: S109-S115...[10-4-30]
Rhodiola algida improves chemotherapy-induced oral mucositis in breast cancer patients
Loo WTY , Jin LJ, Chow LWC, Cheung MNB, Wang M. Expert Opin Investig Drugs. 2010;19 Suppl 1: S91-100...[10-4-30]
Evolution of endocrine adjuvant therapy for early breast cancer
Per Eystein Lønning. Expert Opin Investig Drugs. 2010;19 Suppl 1: S19-30...[10-4-30]
Gene expression profiles as an additional tool to conventional predictive factors to assist in management of early endocrine responsive breast cancer
Chow LWC. Expert Opin Investig Drugs. 2010;19 Suppl 1: S13-S17....[10-4-30]
Combat against cancer with science and medicine
Chow LWC and Toi M. Expert Opin Investig Drugs. 2010;19 Suppl 1: S3-4....[10-4-30]
Evaluation of the psychological and biological changes of patients diagnosed with benign and malignant breast tumor
Bai LJ, Liu Q, Wang M, Loo WT, Cheng RW, Chow LW, Cheung MN, Wei KY, Yip AY, Ng EL. Int J Biol Markers. 2012 Nov 23:0. doi: 10.5301/JBM.2012.9936 ...[13-1-9]
Correlation of epigenetic change and identification of risk factors for oral submucous fibrosis
Xu C, Zhao J, Loo WT, Hao L, Wang M, Cheung MN, Dou Y, Yip AY, Ng EL, Chow LW, Liu Q. Int J Biol Markers. 2012 Nov 23:0. doi: 10.5301/JBM.2012.9937 ...[13-1-9]
The clinical trials of the Organisation for Oncology and Translational Research (OOTR)
Chow LW, Toi M. Int J Biol Markers. 2012 Dec 14:0. doi: 10.5301/JBM.2012.10371 ...[13-1-9]
Prevention of oncological diseases: primary and secondary prevention
Chow LW, Yip AY, Ng EL. Int J Biol Markers. 2012 Dec 14:0. doi: 10.5301/JBM.2012.10370 ...[13-1-9]
Methods of early detection – Would clinical breast examination and breast ultrasonography a good alternative to mammography?
Adrian Y.S. Yip, W.P. Chu, Louis W.C. Chow, Wings T.Y. Loo, Eleanor Y.Y. Ong, Wincy Chan. Chin J Breast Dis (Electronic Edition), December 2011, Vol.5, No.6, Pages 646-659...[11-12-31]
Selected Special Lectures of OOTR 7th Annual Conference, 2011
This page is supported by an educational grant from GSK...[11-12-14]
Year in review in Asia - The major Asian trials published in 2011 on Breast Cancer
Louis W.C. Chow, Adrian Y.S. Yip, Wai-pui Chu, Eleanor Y.Y. Ong. The Journal of Japan Society of Clinical Oncology, Volume 46, Number 3, 13 Sep 2011, Pages 1176-1181...[11-10-27]
Translational research to realize the full potential of novel agents - an opportunity for vinflunine?
Yip AYS, Ong EYY, Chow LWC. Expert Opinion on Drug Safety. 2011 Sep 30 online...[11-9-30]
乳腺癌個體化新輔助治療及輔助手段的套用
周 永昌,魯慶榮,葉潤燊. 中國臨床腫瘤學進展2011 (The 14th Annual Meeting of Chinese Society of Clinical Oncology (CSCO) Educational Book, Sep 2011, Article 37)...[11-9-19]
Racial differences in acute toxicities of neoadjuvant or adjuvant chemotherapy in patients with early-stage breast cancer
Han HS, Reis IM, Zhao W, Kuroi K, Toi M, Suzuki E, Syme R, Chow LWC, Yip AYS, Glück S. Eur J Cancer. 2011 Jul 7...[11-7-7]
Bone metabolism and quality-of-life of postmenopausal women with invasive breast cancer receiving neoadjuvant hormonal therapy: Sub-analyses from celecoxib anti-aromatase neoadjuvant (CAAN) trial
Louis W.C. Chow, Adrian Y.S. Yip, W.P. Chu, Wings T.Y. Loo, and Masakazu Toi. The Journal of Steroid Biochemistry and Molecular Biology, Volume 125, Issues 1-2, May 2011, Pages 112-119...[11-5-1]
Application of biomarkers in sentinel lymph node biopsy for the management of breast cancer
Qing Liu,Wings Tjing Yung Loo,Adrian Yun San Yip,Louis Wing Cheong Chow,Elizabeth Lam Yan Ng,Mary Ngan Bing Cheung. Chin J Breast Dis( Electronic Edition),December 2012,Vol. 6,No. 6...[12-12-31]
Preoperative systemic therapy in locoregional management of early breast cancer: highlights from the Kyoto Breast Cancer Consensus Conference
Toi M, Benson JR, Winer EP, Forbes JF, von Minckwitz G, Golshan M, Robertson JF, Sasano H, Cole BF, Chow LW, Pegram MD, Han W, Huang CS, Ikeda T, Kanao S, Lee ES, Noguchi S, Ohno S, Partridge AH, Rouzier R, Tozaki M, Sugie T, Yamauchi A, Inamoto T. Breast Cancer Res Treat. 2012 Nov 11 ...[12-11-16]
具抗藥性乳腺癌病人的組合性用藥治療方案及其療效和監察的探討
Louis W.C. CHOW, Adrian Y.S. YIP, Qing LIU, Wings T.Y. LOO. The 15th Annual Meeting of Chinese Society of Clinical Oncology (CSCO) Educational Book中國臨床腫瘤學進展2012, pages 240-242 ...[12-9-20]
國際乳腺癌臨床研究現狀及展望
周永昌,魯慶榮. 實用乳腺病學, pages 5-24...[12-9-1]
LMTK3 is implicated in endocrine resistance via multiple signaling pathways
Stebbing J, Filipovic A, Lit LC, Blighe K, Grothey A, Xu Y, Miki Y, Chow LW, Coombes RC, Sasano H, Shaw JA, Giamas G. Oncogene. 2012 Aug 6. doi: 10.1038/onc.2012.343. ...[12-8-6]
New therapies in HER2-positive breast cancer: A major step towards a cure of the disease?
Awada A, Bozovic-Spasojevic I, Chow L. Cancer Treat Rev. 2012Aug; 38(5): 494-504...[12-8-1]
Predictions of the pathological response to neoadjuvant chemotherapy in patients with primary breast cancer using a data mining technique
Takada M, Sugimoto M, Ohno S, Kuroi S, Sato N, Bando H, Masuda N, Iwata H, Kondo M, Ssano H, Chow LW, Inamoto T, Naito Y, Tomita M, Toi M. Breast Cancer Res Treat. Jun 2012...[12-6-12]
Aromatase inhibitor treatment of breast cancer cells increases the expression of let-7f, a microRNA targeting CYP19A1
Yukiko Shibahara,Yasuhiro Miki,Yoshiaki Onodera,Shuko Hata,Monica SM Chan,Christopher CP Yiu,Tjing Y Loo,Yasuhiro Nakamura,Jun-ichi Akahira,Takanori Ishida,Keiko Abe,Hisashi Hirakawa,Louis WC Chow,Takashi Suzuki,Noriaki Ouchi,Hironobu Sasano. The Journal of Pathology, 30 Apr 2012...[12-4-30]
Effect of Sanguisorba officinalis L on breast cancer growth and angiogenesis
ZhiYu Wang, Wings TY Loo, Neng Wang, Louis WC Chow, Dongmei Wang, Feng Han, Xiao Zheng, Jian-Ping Chen. Expert Opinion on Therapeutic Targets, March 2012, Vol. 16, No. S1, Pages S79-S89...[12-3-30]
Understanding Intratumor Heterogeneity
Louis Wing-cheong Chow. The 16th Annual Meeting of Chinese Society of Clinical Oncology (CSCO) Educational Book中國臨床腫瘤學進展2013, pages 505-508...[13-9-26]
Estrogen-receptor antagonist in a premenopausal patient with metastatic breast cancer
Chi-Kei Lam, Louis Wing-cheong Chow. Oncology Tribune, May-Jun 2013, P.15-17...[13-6-30]
Status of oral ulcerative mucositis and biomarkers to monitor posttraumatic stress disorder effects in breast cancer patients
Loo WT, Liu Q, Yip MC, Wang M, Chow LW, Cheung MN, Yip AY, Ng EL. Int J Biol Markers2013 Jun 28;28(2):e168-73...[13-6-28]
New developments in breast cancer prognosis: molecular 
predictors of treatment response and survival
Foo EM, Boost MV, Wong AS,Loo WT,Chow LW, Chow CY. Int J Biol Markers2013 Jun 28;28(2):e131-40...[13-6-28]
Association of cytokines, high sensitive C-reactive protein, VEGF and beta-defensin-1 gene polymorphisms and their protein expressions with chronic periodontitis in the Chinese population
Tian Y, Li JL, Hao L, Yue Y, Wang M, Loo WT, Cheung MN,Chow LW, Liu Q, Yip AY, Ng EL, Chow CY, Chow2 CY. Int J Biol Markers 2013 Apr 23;28(1):e100-e107...[13-4-23]
Application of interleukin-1 genes and proteins to monitor the status of chronic periodontitis
Hao L, Li JL, Yue Y, Tian Y, Wang M, Loo WT, Cheung MN,Chow LW, Liu Q, Yip AY, Ng EL. Int J Biol Markers 2013 Apr 23;28(1):e92-9...[13-4-23]
Acceptable cardiac safety profile of neoadjuvant 5-fluorouracil, epirubicin, cyclophosphamide and celecoxib (FEC-C) for breast cancer: a subanalysis of biomarkers for cardiac injury
Chow LW, Loo WT, Yip AY, Ng EL. Int J Biol Markers2013 Apr 23;28(1):e92-9...[13-4-23]
Concurrent celecoxib with 5-fluorouracil/epirubicin/cyclophosphamide followed by docetaxel for stages II - III invasive breast cancer: the OOTR-N001 study
Chow LW, Tung SY, Ng TY, Im SA, Lee MH, Yip AY, Toi M, Glück S. Expert Opin Investig Drugs. 2013 Mar;22(3):299-307 ...[13-3-1]
Randomized Phase III Placebo-Controlled Trial of Letrozole Plus Oral Temsirolimus As First-Line Endocrine Therapy in Postmenopausal Women With Locally Advanced or Metastatic Breast Cancer
Antonio C. Wolff, Ann A. Lazar, Igor Bondarenko, August M. Garin, Stephen Brincat, Louis Chow, Yan Sun, Zora Neskovic-Konstantinovic, Rodrigo C. Guimaraes, Pierre Fumoleau, Arlene Chan, Soulef Hachemi, Andrew Strahs, Maria Cincotta, Anna Berkenblit, Mizue Krygowski, Lih Lisa Kang, Laurence Moore, Daniel F. Hayes. J Clin Oncol. 2013 Jan 10;31(2):195-202. doi: 10.1200/JCO.2011.38.3331 ...[13-1-13]
Changes of tumor infiltrating lymphocyte subtypes before and after neoadjuvant endocrine therapy in estrogen receptor-positive breast cancer patients - an immunohistochemical study of cd8+ and foxp3+ using double immunostaining with correlation to the pat
Chan MS, Wang L, Felizola SJ, Ueno T, Toi M, Loo W, Chow LW, Suzuki T, Sasano H. Int J Biol Markers. 2012 Dec 19:0. doi: 10.5301/JBM.2012.10439 ...[13-1-10]
Evaluation of the psychological and biological changes of patients diagnosed with benign and malignant breast tumor
Bai LJ, Liu Q, Wang M, Loo WT, Cheng RW, Chow LW, Cheung MN, Wei KY, Yip AY, Ng EL. Int J Biol Markers. 2012 Nov 23:0. doi: 10.5301/JBM.2012.9936 ...[13-1-9]
Correlation of epigenetic change and identification of risk factors for oral submucous fibrosis
Xu C, Zhao J, Loo WT, Hao L, Wang M, Cheung MN, Dou Y, Yip AY, Ng EL, Chow LW, Liu Q. Int J Biol Markers. 2012 Nov 23:0. doi: 10.5301/JBM.2012.9937 ...[13-1-9]
The clinical trials of the Organisation for Oncology and Translational Research (OOTR)
Chow LW, Toi M. Int J Biol Markers. 2012 Dec 14:0. doi: 10.5301/JBM.2012.10371 ...[13-1-9]
Prevention of oncological diseases: primary and secondary prevention
Chow LW, Yip AY, Ng EL. Int J Biol Markers. 2012 Dec 14:0. doi: 10.5301/JBM.2012.10370 ...[13-1-9]

獲獎記錄

2012年,他獲得中華醫學會乳腺癌專業委員會頒發的“金顯宅乳腺癌研究紀念獎”,為港澳地區目前唯一獲得此榮譽的專家。

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