余鵬(中南大學湘雅藥學院碩士研究生導師)

余鵬，博士，副教授，中南大學湘雅藥學院碩士研究生導師。2007年6月畢業於中國藥科大學藥物分析學專業，獲理學博士學位，其後至今在中南大學藥學院工作。

基本介紹

• 中文名：余鵬
• 國籍：中國
• 出生日期：1978年11月
• 畢業院校：中國藥科大學
• 學位/學歷：博士

研究方向

主要研究方向為生物分子識別的機制研究及套用開發，發表高水平學術論文300餘篇，其中以第一作者/通訊作者發表56篇，申請專利28項，已授權7項，主持及參與國家、省、市等各級科研項目22項，指導學生獲獎22項。

研究課題

1. 湖南省自然科學基金——科藥聯合基金基於核酸適配體的手性藥物拆分方法的理論可行性研究（2022JJ80105）。執行年限：2022.1-2024.12.

2. 湖南省自然科學基金項目，基於生物質譜法定量耐藥細胞轉運蛋白表達量的方法建立及其在檢測腫瘤細胞耐藥指數上的套用（2018JJ2415）。執行年限：2018.1-2020.1.

3. 2018年師生共創立項項目，癌症個體化用藥技術平台-基於人工智慧的精準給藥（2018gczd032）。執行年限：2018.11-2019.12.

發表論文

[1]Jie Y ,Xiaoling L ,Meilun C , et al.Non-immobilized GO-SELEX screening of aptamers against cyclosporine A and its application in a AuNPs colorimetric aptasensor.[J].Analytical methods : advancing methods and applications,2023, IF=3.1,JCR分區：Q2

[2]Yijie L ,Xiaoling L ,Meilun C , et al.Advances in screening, synthesis, modification, and biomedical applications of peptides and peptide aptamers.[J].BioFactors (Oxford, England),2023, IF=6.0,JCR分區：Q1

[3]Yijie L ,Jie Y ,Meilun C , et al.Recent advances in computer-aided virtual screening and docking optimization for aptamer.[J].Current topics in medicinal chemistry,2023,23(20):1985-2000.IF=3.041,JCR分區：Q1

[4]Hanbing J ,Jie Y ,Yucui H , et al.Evaluation of intracellular metabolism of methotrexate in hepatocytes and embryonic kidney cells based on Folylpolyglutamate Synthetase and gamma-Glutamyl Hydrolase expression.[J].Current drug metabolism,2023,24(2),IF=3.408,JCR分區：Q2

[5]Yucui H ,Xiaoling L ,Jie Y , et al.A label-free fluorescent aptamer sensor for testosterone based on SYBR Green I.[J].Analytical methods : advancing methods and applications,2023,15(12),IF=3.1,JCR分區：Q2

[6]Huanhuan Li, Tongji Cai, Yi Ren, Jing Huang, Hanbing Jiang, Yucui Hou, Chunhua Tang, Jie Yang, Jia Zhao，Peng Yu *. A simple unlabeled human chorionic gonadotropin biosensor based on a peptide aptamer. Analytical Methods，7 Sep 2021. doi: 10.1039/d1ay01105g. IF=2.596; JCR分區：Q2

[7]Zhonghua Ouyang , Jing Huang, Yi Ren, Huanhuan Li, Yao Ding, Ke Zhang, Lei Jiang, Peng Yu*.(2021).Studies on the intracellular accumulation process of methotrexate and its correlation with the key protein using an LC-MS/MS method: a novel way to realize prospective individualized medication.. Analytical and bioanalytical chemistry，Mar 2021, 413: 1799-1807. doi:10.1007/S00216-020-03125-2. IF=3.63; JCR分區：Q1

[8]Yi Ren, Yao Ding, Fanqi Meng, Lei Jiang, Huanhuan Li, Jing Huang, Peng Yu*, Zhaohui Qiu*. Quantification of CYP2E1 in rat liver by UPLC-MS/MS-based targeted proteomics assay: a novel approach for enzyme activity assessment. Analytical and bioanalytical chemistry，25 June 2020. doi:10.1007/s00216-020-02757-8. IF=3.637; JCR分區：Q1

[9]Huanhuan Li, Fanqi Meng, Lei Jiang, Zhaohui Qiu, Peng Yu*. Comparison of LC-MS/MS-based targeted proteomics and conventional analytical methods for monitoring breast cancer resistance protein expression. Life Sciences. 231(2019). IF= 3.448; JCR分區：Q1

[10]Lei Jiang, Fanqi Meng, Zhaohui Qiu, Ke Zhang, Yao Ding, Huanhuan Li, Yi Ren, Peng Yu*, Jie Peng. Comparison of UPLC-MS/MS-based targeted quantitation and conventional quantitative methods for the analysis of MRP1 expression in tumor cell lines. Journal of Chromatography B. 2019, 1109:10-18. IF= 2.813; JCR分區：Q2

獲批專利

1. 余鵬、江寒冰、張可、丁堯；一種預測甲氨蝶呤藥效的肽段組合物及其定量檢測方法與檢測試劑盒，2021.03.26，中國，ZL201911064881.2

2. 余鵬、李歡歡、孟凡奇、蔣蕾、任藝；甲氨蝶呤給藥方案確定方法、裝置、儲存介質及設備，2019.05.14，中國，CN109754858A

3. 余鵬、蔣蕾、孟凡奇、丁堯；用於FPGS和GGH蛋白表達量檢測的特徵性多肽及其套用，2021.03.26，中國，ZL201910711103.1

4. 余鵬、蔣蕾、孟凡奇；一種估算齊多夫定藥時曲線下面積的方法，2020.01.10，中國，CN110675961A