個人經歷
受教育經歷
2001/09 – 2007/02,湖南大學,化學化工學院,博士
1998/09 – 2001/06,南華大學,化學化工學院,本科
研究工作經歷
2007/06–2009/08,
美國馬里蘭大學,美國食品與藥物管理局(FDA),博士後
2011/01–2013/02, 中南大學,化學化工學院分析科學系,副教授
2013年3月聘為中南大學“升華學者”特聘教授。
研究方向
主要科研方向:生物納米材料製備與套用
(1) 將生物納米材料,如碳納米材料、
金屬納米材料、螢光納米材料等套用於血清中生物標誌物(腫瘤標誌物、DNA、miRNA)檢測,用於疾病早期診斷。
(2) 將製備的生物納米材料用於抗菌及腫瘤治療。
學術成果
主要科研業績
多年來一直從事生物納米材料、生物感測、微流控晶片等領域相關研究工作。在納米材料合成,修飾以及生物分析檢測方面具有較豐富的經驗。以第一作者或通訊作者在《Analytical Chemistry》,《Chemical Communications》,《Biomaterials》, 《Lab-on-a-chip》、《Biosensors Bioelectronics》等雜誌發表SCI學術論文100餘篇。其中影響因子在5以上的有27篇,影響因子在7以上的有5篇,包括《Analytical Chemistry》10篇,《Chemical Communications》2篇,《Biomaterials》5篇,《Lab-on-a-chip》2篇,《Biosensors Bioelectronics》16篇,論文總共被引用1500餘次,個人H因子為23。
主要論文:
(1)Electrochemical Detection of Circulating Tumor Cells Based on DNA Generated Electrochemical Current and Rolling Circle Amplification,Analytical Chemistry,2019,91, 11614−11619.
(2)Biomimetic Mineralization Guided One-Pot Preparation of Gold clusters Anchored Two-Dimensional MnO2 Nanosheets for Fluorometric/Magnetic Bimodal Sensing, Analytical Chemistry,2018, 90, 2926−2932.
(3)Polycytosine DNA Electric-Current-Generated Immunosensor for Electrochemical Detection of Human Epidermal Growth Factor Receptor 2 (HER2),Analytical Chemistry,2018, 90, 4764−4769.
(4)Self-Assembled DNA Generated Electric Current Biosensor for HER2 Analysis, Analytical Chemistry,2017, 89, 10264−10269
(5)DNA Generated Electric Current Biosensor,Analytical Chemistry.2017, 89, 2547−2552
(6)Dual signal amplification electrochemical biosensor for monitoring the activity and inhibition of the Alzheimer related protease β-secretase (BACE1),Analytical. Chemistry.2016, 88, 10559-10565
(7) Silver Nanoclusters-Based Fluorescence Assay of Protein Kinase Activity and Inhibition, Anal. Chem.2015, 87, 693−698
(8) Electrochemical biosensing platform using hydrogel prepared from ferrocene modified amino acid as highly efficient immobilization matrix. Analytical Chemistry, 2014, 86, 973-976.
(9)When protein-based biomineralization meets hydrothermal synthesis: the nanostructures of the
as-prepared materials are independent of the protein types, Chem. Commun.,2015,51, 17076--17079
(10) Carbon Nanotubes based Enhanced Chemiluminescence (CNT-ECL) Immunodetection of Staphylococcal Enterotoxin B (SEB) in Food, Anal.Chem., 2008, 80, 8532-8537.
(11) Electrical percolation biological semiconductor, Anal. Chem.,2010, 82, 3567-3572.
(12) Point-of-care immunosensor for the detection of cancer biomarker based on percolated graphene thin film, Chem.Commun. 2010, 5796-5798.